메뉴 건너뛰기




Volumn 13, Issue 9, 2015, Pages 1061-1064

HER2-mutated breast cancer responds to treatment with single-agent neratinib, a second-generation HER2/EGFR tyrosine kinase inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

CAPECITABINE; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FULVESTRANT; LAPATINIB; LETROZOLE; LOPERAMIDE; NAVELBINE; NERATINIB; PROGESTERONE RECEPTOR; PROTEIN MDM2; TAMOXIFEN; TRASTUZUMAB; TUMOR MARKER; ZOLEDRONIC ACID; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN; N-(4-(3-CHLORO-4-(2-PYRIDINYLMETHOXY)ANILINO)-3-CYANO-7-ETHOXY-6-QUINOLYL)-4-(DIMETHYLAMINO)-2-BUTENAMIDE; PROTEIN KINASE INHIBITOR; QUINOLINE DERIVATIVE;

EID: 84941760766     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2015.0131     Document Type: Article
Times cited : (77)

References (15)
  • 1
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumors
    • The Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumors. Nature 2012;490:61-70.
    • (2012) Nature , vol.490 , pp. 61-70
    • The Cancer Genome Atlas Network1
  • 2
    • 84873918443 scopus 로고    scopus 로고
    • Activating HER2 mutations in HER2 gene amplification negative breast cancer
    • Bose R, Kavuri SM, Searleman AC, et al. Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer Discov 2013;3:224-237.
    • (2013) Cancer Discov , vol.3 , pp. 224-237
    • Bose, R.1    Kavuri, S.M.2    Searleman, A.C.3
  • 3
    • 84865994665 scopus 로고    scopus 로고
    • Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2
    • Greulich H, Kaplan B, Mertins P, et al. Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2. Proc Natl Acad Sci U S A 2012;109:14476-14481.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 14476-14481
    • Greulich, H.1    Kaplan, B.2    Mertins, P.3
  • 4
    • 80055032877 scopus 로고    scopus 로고
    • Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib
    • Kancha RK, von Bubnoff N, Bartosch N, et al. Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib. PLoS ONE 2011;6:e26760.
    • (2011) PLoS ONE , vol.6 , pp. e26760
    • Kancha, R.K.1    Von Bubnoff, N.2    Bartosch, N.3
  • 5
    • 84886442748 scopus 로고    scopus 로고
    • Human breast cancer cells harboring a gatekeeper T798M mutation in HER2 overexpress EGFR ligands and are sensitive to dual inhibition of EGFR and HER2
    • Rexer BN, Ghosh R, Narasanna A, et al. Human breast cancer cells harboring a gatekeeper T798M mutation in HER2 overexpress EGFR ligands and are sensitive to dual inhibition of EGFR and HER2. Clin Cancer Res 2013;19:5390-5401.
    • (2013) Clin Cancer Res , vol.19 , pp. 5390-5401
    • Rexer, B.N.1    Ghosh, R.2    Narasanna, A.3
  • 6
    • 65349110371 scopus 로고    scopus 로고
    • Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: German Breast Group 26/Breast International Group 03-05 study
    • von Minckwitz G, du Bois A, Schmidt M, et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: German Breast Group 26/Breast International Group 03-05 study. J Clin Oncol 2009;27:1999-2006.
    • (2009) J Clin Oncol , vol.27 , pp. 1999-2006
    • Von Minckwitz, G.1    Du Bois, A.2    Schmidt, M.3
  • 7
    • 84905469625 scopus 로고    scopus 로고
    • Response of an ERBB2-mutated inflammatory breast carcinoma to human epidermal growth factor receptor 2-targeted therapy
    • Ali SM, Alpaugh RK, Downing SR, et al. Response of an ERBB2-mutated inflammatory breast carcinoma to human epidermal growth factor receptor 2-targeted therapy. J Clin Oncol 2014;32:e88-91.
    • (2014) J Clin Oncol , vol.32 , pp. e88-e91
    • Ali, S.M.1    Alpaugh, R.K.2    Downing, S.R.3
  • 8
    • 84878551145 scopus 로고    scopus 로고
    • Combination neratinib (HKI-272) and paclitaxel therapy in patients with HER2-positive metastatic breast cancer
    • Chow LW, Xu B, Gupta S, et al. Combination neratinib (HKI-272) and paclitaxel therapy in patients with HER2-positive metastatic breast cancer. Br J Cancer 2013;108:1985-1993.
    • (2013) Br J Cancer , vol.108 , pp. 1985-1993
    • Chow, L.W.1    Xu, B.2    Gupta, S.3
  • 9
    • 84871595073 scopus 로고    scopus 로고
    • Safety and efficacy of neratinib (HKI-272) plus vinorelbine in the treatment of patients with ErbB2-positive metastatic breast cancer pretreated with anti-HER2 therapy
    • Awada A, Dirix L, Manso Sanchez L, et al. Safety and efficacy of neratinib (HKI-272) plus vinorelbine in the treatment of patients with ErbB2-positive metastatic breast cancer pretreated with anti-HER2 therapy. Ann Oncol 2013;24:109-116.
    • (2013) Ann Oncol , vol.24 , pp. 109-116
    • Awada, A.1    Dirix, L.2    Manso Sanchez, L.3
  • 10
    • 84864778959 scopus 로고    scopus 로고
    • Safety and efficacy of neratinib in combination with capecitabine in patients with ErbB2-positive breast cancer [abstract]
    • P1-12-09
    • Saura C, Garcia-Saenz JA, Xu B, et al. Safety and efficacy of neratinib in combination with capecitabine in patients with ErbB2-positive breast cancer [abstract]. Cancer Res 2011;71(24 Suppl):Abstract P1-12-09.
    • (2011) Cancer Res , vol.71 , Issue.24
    • Saura, C.1    Garcia-Saenz, J.A.2    Xu, B.3
  • 11
    • 84894807977 scopus 로고    scopus 로고
    • Phase I study of neratinib in combination with temsirolimus in patients with human epidermal growth factor receptor 2-dependent and other solid tumors
    • Gandhi L, Bahleda R, Tolaney SM, et al. Phase I study of neratinib in combination with temsirolimus in patients with human epidermal growth factor receptor 2-dependent and other solid tumors. J Clin Oncol 2014;32:68-75.
    • (2014) J Clin Oncol , vol.32 , pp. 68-75
    • Gandhi, L.1    Bahleda, R.2    Tolaney, S.M.3
  • 12
    • 84884712921 scopus 로고    scopus 로고
    • Combined inhibition of mTORC1 with temsirolimus and HER2 with neratinib: A phase I/II study in patients with metastatic HER2-amplified or triple-negative breast cancer [abstract]
    • PD 09-08
    • Gajria D, King T, Pannu H, et al. Combined inhibition of mTORC1 with temsirolimus and HER2 with neratinib: a phase I/II study in patients with metastatic HER2-amplified or triple-negative breast cancer [abstract]. Cancer Res 2011;71(24 Suppl):Abstract PD 09-08.
    • (2011) Cancer Res , vol.71 , Issue.24
    • Gajria, D.1    King, T.2    Pannu, H.3
  • 13
    • 84890405678 scopus 로고    scopus 로고
    • Safety and efficacy of neratinib in combination with weekly paclitaxel and trastuzumab in women with metastatic HER2positive breast cancer: An NSABP Foundation Research Program phase I study
    • Jankowitz RC, Abraham J, Tan AR, et al. Safety and efficacy of neratinib in combination with weekly paclitaxel and trastuzumab in women with metastatic HER2positive breast cancer: an NSABP Foundation Research Program phase I study. Cancer Chemother Pharmacol 2013;72:1205-1212.
    • (2013) Cancer Chemother Pharmacol , vol.72 , pp. 1205-1212
    • Jankowitz, R.C.1    Abraham, J.2    Tan, A.R.3
  • 14
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • The Cancer Genome Atlas Consortium. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487:330-337.
    • (2012) Nature , vol.487 , pp. 330-337
    • The Cancer Genome Atlas Consortium1
  • 15
    • 84897022815 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of urothelial bladder carcinoma
    • The Cancer Genome Atlas Network. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 2014;507:315-322.
    • (2014) Nature , vol.507 , pp. 315-322
    • The Cancer Genome Atlas Network1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.