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Volumn 10, Issue 7, 2015, Pages

Schizophrenia related variants in CACNA1C also confer risk of autism

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ARTICLE; AUTISM; CACNA1C GENE; CHILD; CONTROLLED STUDY; FEMALE; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAN CHINESE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MINOR ALLELE FREQUENCY; MUTATIONAL ANALYSIS; PATHOGENESIS; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; TIMOTHY SYNDROME; TREND STUDY; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; PRESCHOOL CHILD;

EID: 84941670441     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133247     Document Type: Article
Times cited : (56)

References (65)
  • 1
    • 0033802632 scopus 로고    scopus 로고
    • The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism
    • 11055457
    • Lord C, Risi S, Lambrecht L, Cook EH Jr, Leventhal BL, Di Lavore PC, et al. The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord. 2000;30:205-223. PMID: 11055457
    • (2000) J Autism Dev Disord. , vol.30 , pp. 205-223
    • Lord, C.1    Risi, S.2    Lambrecht, L.3    Cook, E.H.4    Leventhal, B.L.5    Di Lavore, P.C.6
  • 2
    • 0035653670 scopus 로고    scopus 로고
    • Genetics of autism: Complex aetiology for a heterogeneous disorder
    • 11733747
    • Folstein SE, Rosen-Sheidley B. Genetics of autism: complex aetiology for a heterogeneous disorder. Nat Rev Genet. 2001;2:943-955. PMID: 11733747
    • (2001) Nat Rev Genet. , vol.2 , pp. 943-955
    • Folstein, S.E.1    Rosen-Sheidley, B.2
  • 3
    • 84871298155 scopus 로고    scopus 로고
    • Common genetic variants, acting additively, are a major source of risk for autism
    • 23067556
    • Klei L, Sanders SJ, Murtha MT, Hus V, Lowe JK, Willsey AJ, et al. Common genetic variants, acting additively, are a major source of risk for autism. Mol Autism. 2012;3:9. doi: 10.1186/2040-2392-3-9 PMID: 23067556
    • (2012) Mol Autism. , vol.3 , pp. 9
    • Klei, L.1    Sanders, S.J.2    Murtha, M.T.3    Hus, V.4    Lowe, J.K.5    Willsey, A.J.6
  • 4
    • 84890022588 scopus 로고    scopus 로고
    • Independent modulation of engagement and connectivity of the facial network during affect processing by CACNA1C and ANK3 risk genes for bipolar disorder
    • 24108394
    • Dima D, Jogia J, Collier D, Vassos E, Burdick KE, Frangou S. Independent modulation of engagement and connectivity of the facial network during affect processing by CACNA1C and ANK3 risk genes for bipolar disorder. JAMA Psychiatry. 2013;70:1303-1311. doi: 10.1001/jamapsychiatry.2013.2099 PMID: 24108394
    • (2013) JAMA Psychiatry , vol.70 , pp. 1303-1311
    • Dima, D.1    Jogia, J.2    Collier, D.3    Vassos, E.4    Burdick, K.E.5    Frangou, S.6
  • 5
    • 27344432023 scopus 로고    scopus 로고
    • Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory
    • 16251435
    • Moosmang S, Haider N, Klugbauer N, Adelsberger H, Langwieser N, Muller J, et al. Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory. J Neurosci. 2005;25:9883-9892. PMID: 16251435
    • (2005) J Neurosci. , vol.25 , pp. 9883-9892
    • Moosmang, S.1    Haider, N.2    Klugbauer, N.3    Adelsberger, H.4    Langwieser, N.5    Muller, J.6
  • 6
    • 50449089356 scopus 로고    scopus 로고
    • Collaborative genomewide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
    • 18711365
    • Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, et al. Collaborative genomewide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet. 2008;40:1056-1058. doi: 10.1038/ng.209 PMID: 18711365
    • (2008) Nat Genet. , vol.40 , pp. 1056-1058
    • Ferreira, M.A.1    O'Donovan, M.C.2    Meng, Y.A.3    Jones, I.R.4    Ruderfer, D.M.5    Jones, L.6
  • 7
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls
    • 17554300
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature. 2007;447:661-678. PMID: 17554300
    • (2007) Nature , vol.447 , pp. 661-678
    • Wellcome Trust Case Control Consortium1
  • 9
    • 77954510735 scopus 로고    scopus 로고
    • The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia
    • Green EK, Grozeva D, Jones I, Jones L, Kirov G, Caesar S, et al. The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry. 2012;15:1016-1022.
    • (2012) Mol Psychiatry , vol.15 , pp. 1016-1022
    • Green, E.K.1    Grozeva, D.2    Jones, I.3    Jones, L.4    Kirov, G.5    Caesar, S.6
  • 11
    • 84878220679 scopus 로고    scopus 로고
    • Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC
    • 22614287
    • Hamshere ML, Walters JT, Smith R, Richards AL, Green E, Grozeva D, et al. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Mol Psychiatry. 2013;18:708-712. doi: 10.1038/mp. 2012.67 PMID: 22614287
    • (2013) Mol Psychiatry , vol.18 , pp. 708-712
    • Hamshere, M.L.1    Walters, J.T.2    Smith, R.3    Richards, A.L.4    Green, E.5    Grozeva, D.6
  • 12
    • 77956359560 scopus 로고    scopus 로고
    • Genetic variation in CACNA1C affects brain circuitries related to mental illness
    • 20819988
    • Bigos KL, Mattay VS, Callicott JH, Straub RE, Vakkalanka R, Kolachana B, et al. Genetic variation in CACNA1C affects brain circuitries related to mental illness. Arch Gen Psychiatry. 2010;67:939-945. doi: 10.1001/archgenpsychiatry.2010.96 PMID: 20819988
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 939-945
    • Bigos, K.L.1    Mattay, V.S.2    Callicott, J.H.3    Straub, R.E.4    Vakkalanka, R.5    Kolachana, B.6
  • 13
    • 84908021757 scopus 로고    scopus 로고
    • Replication of previous genome-wide association studies of psychiatric diseases in a large schizophrenia case-control sample from Spain
    • 25124521
    • Ivorra JL, Rivero O, Costas J, Iniesta R, Arrojo M, Ramos-Rios R, et al. Replication of previous genome-wide association studies of psychiatric diseases in a large schizophrenia case-control sample from Spain. Schizophr Res. 2014;159:107-113. doi: 10.1016/j.schres.2014.07.004 PMID: 25124521
    • (2014) Schizophr Res. , vol.159 , pp. 107-113
    • Ivorra, J.L.1    Rivero, O.2    Costas, J.3    Iniesta, R.4    Arrojo, M.5    Ramos-Rios, R.6
  • 15
    • 23244451843 scopus 로고    scopus 로고
    • Autism: A window onto the development of the social and the analytic brain
    • 16033325
    • Baron-Cohen S, Belmonte MK. Autism: a window onto the development of the social and the analytic brain. Annu Rev Neurosci. 2005;28:109-126. PMID: 16033325
    • (2005) Annu Rev Neurosci. , vol.28 , pp. 109-126
    • Baron-Cohen, S.1    Belmonte, M.K.2
  • 16
    • 77955403499 scopus 로고    scopus 로고
    • Data and clinical utility should be the drivers of changes to psychiatric classification
    • 20679271 author reply 158-159
    • Craddock N, Owen MJ. Data and clinical utility should be the drivers of changes to psychiatric classification. Br J Psychiatry. 2010;197:158; author reply 158-159. doi: 10.1192/bjp. 197.2.158 PMID: 20679271
    • (2010) Br J Psychiatry , vol.197 , pp. 158
    • Craddock, N.1    Owen, M.J.2
  • 17
    • 58949088309 scopus 로고    scopus 로고
    • Contact in the genetics of autism and schizophrenia
    • 19135727
    • Burbach JP, Van Der Zwaag B. Contact in the genetics of autism and schizophrenia. Trends Neurosci. 2009;32:69-72. doi: 10.1016/j.tins.2008.11.002 PMID: 19135727
    • (2009) Trends Neurosci. , vol.32 , pp. 69-72
    • Burbach, J.P.1    Van Der Zwaag, B.2
  • 18
    • 46449111382 scopus 로고    scopus 로고
    • Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network
    • 18417725
    • Iossifov I, Zheng T, Baron M, Gilliam TC, Rzhetsky A. Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network. Genome Res. 2008;18:1150-1162. doi: 10.1101/gr.075622.107 PMID: 18417725
    • (2008) Genome Res. , vol.18 , pp. 1150-1162
    • Iossifov, I.1    Zheng, T.2    Baron, M.3    Gilliam, T.C.4    Rzhetsky, A.5
  • 19
    • 51449115841 scopus 로고    scopus 로고
    • Variation in GABA-A subunit gene copy number in an autistic patient with mosaic 4 p duplication (p12p16)
    • 18163449
    • Kakinuma H, Ozaki M, Sato H, Takahashi H. Variation in GABA-A subunit gene copy number in an autistic patient with mosaic 4 p duplication (p12p16). Am J Med Genet B Neuropsychiatr Genet. 2008;147 B: 973-975. doi: 10.1002/ajmg.b.30663 PMID: 18163449
    • (2008) Am J Med Genet B Neuropsychiatr Genet. , vol.147 B , pp. 973-975
    • Kakinuma, H.1    Ozaki, M.2    Sato, H.3    Takahashi, H.4
  • 20
    • 38349106160 scopus 로고    scopus 로고
    • Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia
    • 17989066
    • Kirov G, Gumus D, Chen W, Norton N, Georgieva L, Sari M, et al. Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet. 2008;17:458-465. PMID: 17989066
    • (2008) Hum Mol Genet. , vol.17 , pp. 458-465
    • Kirov, G.1    Gumus, D.2    Chen, W.3    Norton, N.4    Georgieva, L.5    Sari, M.6
  • 21
    • 40749089626 scopus 로고    scopus 로고
    • Structural variation of chromosomes in autism spectrum disorder
    • 18252227
    • Marshall CR, Noor A, Vincent JB, Lionel AC, Feuk L, Skaug J, et al. Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet. 2008;82:477-488. doi: 10.1016/j.ajhg.2007. 12.009 PMID: 18252227
    • (2008) Am J Hum Genet. , vol.82 , pp. 477-488
    • Marshall, C.R.1    Noor, A.2    Vincent, J.B.3    Lionel, A.C.4    Feuk, L.5    Skaug, J.6
  • 22
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • 23453885
    • Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013;381:1371-1379. doi: 10.1016/S0140-6736 (12) 62129-1 PMID: 23453885
    • (2013) Lancet , vol.381 , pp. 1371-1379
  • 23
    • 77957130837 scopus 로고    scopus 로고
    • High-density SNP association study of the 17q21 chromosomal region linked to autism identifies CACNA1G as a novel candidate gene
    • 19455149
    • Strom SP, Stone JL, Ten Bosch JR, Merriman B, Cantor RM, Geschwind DH, et al. High-density SNP association study of the 17q21 chromosomal region linked to autism identifies CACNA1G as a novel candidate gene. Mol Psychiatry. 2010;15:996-1005. doi: 10.1038/mp. 2009.41 PMID: 19455149
    • (2010) Mol Psychiatry , vol.15 , pp. 996-1005
    • Strom, S.P.1    Stone, J.L.2    Ten Bosch, J.R.3    Merriman, B.4    Cantor, R.M.5    Geschwind, D.H.6
  • 24
    • 5344223383 scopus 로고    scopus 로고
    • Ca (V) 1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism
    • 15454078
    • Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, et al. Ca (V) 1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell. 2004;119:19-31. PMID: 15454078
    • (2004) Cell , vol.119 , pp. 19-31
    • Splawski, I.1    Timothy, K.W.2    Sharpe, L.M.3    Decher, N.4    Kumar, P.5    Bloise, R.6
  • 25
    • 67349112868 scopus 로고    scopus 로고
    • Common genetic variants on 5p14.1 associate with autism spectrum disorders
    • 19404256
    • Wang K, Zhang H, Ma D, Bucan M, Glessner JT, Abrahams BS, et al. Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature. 2009;459:528-533. doi: 10.1038/nature07999 PMID: 19404256
    • (2009) Nature , vol.459 , pp. 528-533
    • Wang, K.1    Zhang, H.2    Ma, D.3    Bucan, M.4    Glessner, J.T.5    Abrahams, B.S.6
  • 26
    • 0018944406 scopus 로고
    • Behavior checklist for identifying severely handicapped individuals with high levels of autistic behavior
    • 7430288
    • Krug DA, Arick J, Almond P. Behavior checklist for identifying severely handicapped individuals with high levels of autistic behavior. J Child Psychol Psychiatry. 1980;21:221-229. PMID: 7430288
    • (1980) J Child Psychol Psychiatry , vol.21 , pp. 221-229
    • Krug, D.A.1    Arick, J.2    Almond, P.3
  • 27
    • 0018854085 scopus 로고
    • Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS)
    • 6927682
    • Schopler E, Reichler RJ, De Vellis RF, Daly K. Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS). J Autism Dev Disord. 1980;10:91-103. PMID: 6927682
    • (1980) J Autism Dev Disord. , vol.10 , pp. 91-103
    • Schopler, E.1    Reichler, R.J.2    De Vellis, R.F.3    Daly, K.4
  • 28
    • 0035221755 scopus 로고    scopus 로고
    • Automated genotyping using the DNA MassArray technology
    • 11357675
    • Jurinke C, Van Den Boom D, Cantor CR, Koster H. Automated genotyping using the DNA MassArray technology. Methods Mol Biol. 2001;170:103-116. PMID: 11357675
    • (2001) Methods Mol Biol. , vol.170 , pp. 103-116
    • Jurinke, C.1    Van Den Boom, D.2    Cantor, C.R.3    Koster, H.4
  • 31
    • 0034054165 scopus 로고    scopus 로고
    • A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information
    • 10782012
    • Rabinowitz D, Laird N. A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered. 2000;50:211-223. PMID: 10782012
    • (2000) Hum Hered. , vol.50 , pp. 211-223
    • Rabinowitz, D.1    Laird, N.2
  • 37
    • 0028014384 scopus 로고
    • Search for mutations in the beta 1 GABAA receptor subunit gene in patients with schizophrenia
    • 8178835
    • Coon H, Sobell J, Heston L, Sommer S, Hoff M, Holik J, et al. Search for mutations in the beta 1 GABAA receptor subunit gene in patients with schizophrenia. Am J Med Genet. 1994;54:12-20. PMID: 8178835
    • (1994) Am J Med Genet. , vol.54 , pp. 12-20
    • Coon, H.1    Sobell, J.2    Heston, L.3    Sommer, S.4    Hoff, M.5    Holik, J.6
  • 38
    • 0034615152 scopus 로고    scopus 로고
    • Analysis of linkage disequilibrium in gamma-aminobutyric acid receptor subunit genes in autistic disorder
    • 10686550
    • Martin ER, Menold MM, Wolpert CM, Bass MP, Donnelly SL, Ravan SA, et al. Analysis of linkage disequilibrium in gamma-aminobutyric acid receptor subunit genes in autistic disorder. Am J Med Genet. 2000;96:43-48. PMID: 10686550
    • (2000) Am J Med Genet. , vol.96 , pp. 43-48
    • Martin, E.R.1    Menold, M.M.2    Wolpert, C.M.3    Bass, M.P.4    Donnelly, S.L.5    Ravan, S.A.6
  • 40
    • 33845889998 scopus 로고    scopus 로고
    • Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders
    • 17173049
    • Durand CM, Betancur C, Boeckers TM, Bockmann J, Chaste P, Fauchereau F, et al. Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat Genet. 2007;39:25-27. PMID: 17173049
    • (2007) Nat Genet. , vol.39 , pp. 25-27
    • Durand, C.M.1    Betancur, C.2    Boeckers, T.M.3    Bockmann, J.4    Chaste, P.5    Fauchereau, F.6
  • 41
    • 77952374703 scopus 로고    scopus 로고
    • De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia
    • 20385823
    • Gauthier J, Champagne N, Lafreniere RG, Xiong L, Spiegelman D, Brustein E, et al. De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proc Natl Acad Sci U S A. 2010;107:7863-7868. doi: 10.1073/pnas.0906232107 PMID: 20385823
    • (2010) Proc Natl Acad Sci u S A , vol.107 , pp. 7863-7868
    • Gauthier, J.1    Champagne, N.2    Lafreniere, R.G.3    Xiong, L.4    Spiegelman, D.5    Brustein, E.6
  • 42
    • 38749084216 scopus 로고    scopus 로고
    • Disruption of neurexin 1 associated with autism spectrum disorder
    • 18179900
    • Kim HG, Kishikawa S, Higgins AW, Seong IS, Donovan DJ, Shen Y, et al. Disruption of neurexin 1 associated with autism spectrum disorder. Am J Hum Genet. 2008;82:199-207. doi: 10.1016/j.ajhg. 2007.09.011 PMID: 18179900
    • (2008) Am J Hum Genet. , vol.82 , pp. 199-207
    • Kim, H.G.1    Kishikawa, S.2    Higgins, A.W.3    Seong, I.S.4    Donovan, D.J.5    Shen, Y.6
  • 43
    • 13444283651 scopus 로고    scopus 로고
    • A familybased association study and gene expression analyses of netrin-G1 and-G2 genes in schizophrenia
    • 15705354
    • Aoki-Suzuki M, Yamada K, Meerabux J, Iwayama-Shigeno Y, Ohba H, Iwamoto K, et al. A familybased association study and gene expression analyses of netrin-G1 and-G2 genes in schizophrenia. Biol Psychiatry. 2005;57:382-393. PMID: 15705354
    • (2005) Biol Psychiatry , vol.57 , pp. 382-393
    • Aoki-Suzuki, M.1    Yamada, K.2    Meerabux, J.3    Iwayama-Shigeno, Y.4    Ohba, H.5    Iwamoto, K.6
  • 44
    • 84860741138 scopus 로고    scopus 로고
    • Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
    • 22495309
    • O'Roak BJ, Vives L, Girirajan S, Karakoc E, Krumm N, Coe BP, et al. Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature. 2012;485:246-250. doi: 10. 1038/nature10989 PMID: 22495309
    • (2012) Nature , vol.485 , pp. 246-250
    • O'Roak, B.J.1    Vives, L.2    Girirajan, S.3    Karakoc, E.4    Krumm, N.5    Coe, B.P.6
  • 45
    • 77952818259 scopus 로고    scopus 로고
    • Genetic overlap between autism, schizophrenia and bipolar disorder
    • 19886976
    • Carroll LS, Owen MJ. Genetic overlap between autism, schizophrenia and bipolar disorder. Genome Med. 2009;1:102. doi: 10.1186/gm102 PMID: 19886976
    • (2009) Genome Med. , vol.1 , pp. 102
    • Carroll, L.S.1    Owen, M.J.2
  • 46
    • 69949177829 scopus 로고    scopus 로고
    • Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation
    • 19736351
    • Guilmatre A, Dubourg C, Mosca AL, Legallic S, Goldenberg A, Drouin-Garraud V, et al. Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation. Arch Gen Psychiatry. 2009;66:947-956. doi: 10.1001/archgenpsychiatry.2009.80 PMID: 19736351
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 947-956
    • Guilmatre, A.1    Dubourg, C.2    Mosca, A.L.3    Legallic, S.4    Goldenberg, A.5    Drouin-Garraud, V.6
  • 47
    • 84905042733 scopus 로고    scopus 로고
    • Excess of rare novel loss-offunction variants in synaptic genes in schizophrenia and autism spectrum disorders
    • 24126926
    • Kenny EM, Cormican P, Furlong S, Heron E, Kenny G, Fahey C, et al. Excess of rare novel loss-offunction variants in synaptic genes in schizophrenia and autism spectrum disorders. Mol Psychiatry. 2014;19:872-879. doi: 10.1038/mp. 2013.127 PMID: 24126926
    • (2014) Mol Psychiatry , vol.19 , pp. 872-879
    • Kenny, E.M.1    Cormican, P.2    Furlong, S.3    Heron, E.4    Kenny, G.5    Fahey, C.6
  • 48
    • 84883465830 scopus 로고    scopus 로고
    • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
    • 23933821
    • Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013;45:984-994. doi: 10. 1038/ng.2711 PMID: 23933821
    • (2013) Nat Genet. , vol.45 , pp. 984-994
    • Lee, S.H.1    Ripke, S.2    Neale, B.M.3    Faraone, S.V.4    Purcell, S.M.5    Perlis, R.H.6
  • 49
    • 78650856517 scopus 로고    scopus 로고
    • GCTA: A tool for genome-wide complex trait analysis
    • 21167468
    • Yang J, Lee SH, Goddard ME, Visscher PM. GCTA: a tool for genome-wide complex trait analysis. Am J Hum Genet. 2011;88:76-82. doi: 10.1016/j.ajhg.2010.11.011 PMID: 21167468
    • (2011) Am J Hum Genet. , vol.88 , pp. 76-82
    • Yang, J.1    Lee, S.H.2    Goddard, M.E.3    Visscher, P.M.4
  • 50
    • 79952315874 scopus 로고    scopus 로고
    • Is schizophrenia on the autism spectrum?
    • 21078305
    • King BH, Lord C. Is schizophrenia on the autism spectrum? Brain Res. 2011;1380:34-41. doi: 10. 1016/j.brainres.2010.11.031 PMID: 21078305
    • (2011) Brain Res. , vol.1380 , pp. 34-41
    • King, B.H.1    Lord, C.2
  • 52
    • 77957675681 scopus 로고    scopus 로고
    • Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients
    • 20398908
    • Saus E, Brunet A, Armengol L, Alonso P, Crespo JM, Fernandez-Aranda F, et al. Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. J Psychiatr Res. 2010;44:971-978. doi: 10.1016/j.jpsychires.2010.03.007 PMID: 20398908
    • (2010) J Psychiatr Res. , vol.44 , pp. 971-978
    • Saus, E.1    Brunet, A.2    Armengol, L.3    Alonso, P.4    Crespo, J.M.5    Fernandez-Aranda, F.6
  • 53
    • 84899689037 scopus 로고    scopus 로고
    • Rare mutations of CACNB2 found in autism spectrum disease-affected families alter calcium channel function
    • 24752249
    • Breitenkamp AF, Matthes J, Nass RD, Sinzig J, Lehmkuhl G, Nurnberg P, et al. Rare mutations of CACNB2 found in autism spectrum disease-affected families alter calcium channel function. PLoS One. 2014;9:e95579. doi: 10.1371/journal.pone.0095579 PMID: 24752249
    • (2014) PLoS One. , vol.9 , pp. e95579
    • Breitenkamp, A.F.1    Matthes, J.2    Nass, R.D.3    Sinzig, J.4    Lehmkuhl, G.5    Nurnberg, P.6
  • 54
    • 84883495096 scopus 로고    scopus 로고
    • Support for calcium channel gene defects in autism spectrum disorders
    • 23241247
    • Lu AT, Dai X, Martinez-Agosto JA, Cantor RM. Support for calcium channel gene defects in autism spectrum disorders. Mol Autism. 2012;3:18. doi: 10.1186/2040-2392-3-18 PMID: 23241247
    • (2012) Mol Autism. , vol.3 , pp. 18
    • Lu, A.T.1    Dai, X.2    Martinez-Agosto, J.A.3    Cantor, R.M.4
  • 56
    • 55949121591 scopus 로고    scopus 로고
    • Localization and targeting of voltage-dependent ion channels in mammalian central neurons
    • 18923186
    • Vacher H, Mohapatra DP, Trimmer JS. Localization and targeting of voltage-dependent ion channels in mammalian central neurons. Physiol Rev. 2008;88:1407-1447. doi: 10.1152/physrev. 00002.2008 PMID: 18923186
    • (2008) Physiol Rev. , vol.88 , pp. 1407-1447
    • Vacher, H.1    Mohapatra, D.P.2    Trimmer, J.S.3
  • 57
    • 84866551127 scopus 로고    scopus 로고
    • CACNA1C (Cav1.2) in the pathophysiology of psychiatric disease
    • 22705413
    • Bhat S, Dao DT, Terrillion CE, Arad M, Smith RJ, Soldatov NM, et al. CACNA1C (Cav1.2) in the pathophysiology of psychiatric disease. Prog Neurobiol. 2012;99:1-14. doi: 10.1016/j.pneurobio.2012.06. 001 PMID: 22705413
    • (2012) Prog Neurobiol. , vol.99 , pp. 1-14
    • Bhat, S.1    Dao, D.T.2    Terrillion, C.E.3    Arad, M.4    Smith, R.J.5    Soldatov, N.M.6
  • 58
    • 70749086125 scopus 로고    scopus 로고
    • Effect of CACNA1C rs1006737 on neural correlates of verbal fluency in healthy individuals
    • 19781653
    • Krug A, Nieratschker V, Markov V, Krach S, Jansen A, Zerres K, et al. Effect of CACNA1C rs1006737 on neural correlates of verbal fluency in healthy individuals. Neuroimage. 2010;49:1831-1836. doi: 10.1016/j.neuroimage.2009.09.028 PMID: 19781653
    • (2010) Neuroimage , vol.49 , pp. 1831-1836
    • Krug, A.1    Nieratschker, V.2    Markov, V.3    Krach, S.4    Jansen, A.5    Zerres, K.6
  • 60
    • 61849154748 scopus 로고    scopus 로고
    • Aberrant functional connectivity in autism: Evidence from low-frequency BOLD signal fluctuations
    • 19401185
    • Noonan SK, Haist F, Muller RA. Aberrant functional connectivity in autism: evidence from low-frequency BOLD signal fluctuations. Brain Res. 2009;1262:48-63. doi: 10.1016/j.brainres.2008.12.076 PMID: 19401185
    • (2009) Brain Res. , vol.1262 , pp. 48-63
    • Noonan, S.K.1    Haist, F.2    Muller, R.A.3
  • 61
    • 84879085072 scopus 로고    scopus 로고
    • Abnormalities in frontostriatal connectivity within language networks relate to differences in grey-matter heterogeneity in Asperger syndrome
    • 24179823
    • Radulescu E, Minati L, Ganeshan B, Harrison NA, Gray MA, Beacher FD, et al. Abnormalities in frontostriatal connectivity within language networks relate to differences in grey-matter heterogeneity in Asperger syndrome. Neuroimage Clin. 2013;2:716-726. doi: 10.1016/j.nicl.2013.05.010 PMID: 24179823
    • (2013) Neuroimage Clin. , vol.2 , pp. 716-726
    • Radulescu, E.1    Minati, L.2    Ganeshan, B.3    Harrison, N.A.4    Gray, M.A.5    Beacher, F.D.6
  • 62
    • 78649326834 scopus 로고    scopus 로고
    • White matter compromise of callosal and subcortical fiber tracts in children with autism spectrum disorder: A diffusion tensor imaging study
    • 21093776 1278 e1261-1262
    • Shukla DK, Keehn B, Lincoln AJ, Muller RA. White matter compromise of callosal and subcortical fiber tracts in children with autism spectrum disorder: a diffusion tensor imaging study. J Am Acad Child Adolesc Psychiatry. 2010;49:1269-1278, 1278 e1261-1262. doi: 10.1016/j.jaac.2010.08.018 PMID: 21093776
    • (2010) J Am Acad Child Adolesc Psychiatry , vol.49 , pp. 1269-1278
    • Shukla, D.K.1    Keehn, B.2    Lincoln, A.J.3    Muller, R.A.4
  • 63
    • 68049128346 scopus 로고    scopus 로고
    • Development of large-scale functional brain networks in children
    • 19621066
    • Supekar K, Musen M, Menon V. Development of large-scale functional brain networks in children. PLoS Biol. 2009;7:e1000157. doi: 10.1371/journal.pbio.1000157 PMID: 19621066
    • (2009) PLoS Biol. , vol.7 , pp. e1000157
    • Supekar, K.1    Musen, M.2    Menon, V.3
  • 64
    • 84894049091 scopus 로고    scopus 로고
    • Altered functional connectivity of the language network in ASD: Role of classical language areas and cerebellum
    • 24567909
    • Verly M, Verhoeven J, Zink I, Mantini D, Peeters R, Deprez S, et al. Altered functional connectivity of the language network in ASD: Role of classical language areas and cerebellum. Neuroimage Clin. 2014;4:374-382. doi: 10.1016/j.nicl.2014.01.008 PMID: 24567909
    • (2014) Neuroimage Clin. , vol.4 , pp. 374-382
    • Verly, M.1    Verhoeven, J.2    Zink, I.3    Mantini, D.4    Peeters, R.5    Deprez, S.6
  • 65
    • 84989171969 scopus 로고    scopus 로고
    • Reduced beta connectivity during emotional face processing in adolescents with autism
    • 25371811
    • Leung RC, Ye AX, Wong SM, Taylor MJ, Doesburg SM. Reduced beta connectivity during emotional face processing in adolescents with autism. Mol Autism. 2014;5:51. doi: 10.1186/2040-2392-5-51 PMID: 25371811
    • (2014) Mol Autism. , vol.5 , pp. 51
    • Leung, R.C.1    Ye, A.X.2    Wong, S.M.3    Taylor, M.J.4    Doesburg, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.