-
1
-
-
84940474576
-
Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial
-
Normanno N, Rachiglio AM, Lambiase M et al. Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial. Ann Oncol 2015; 26: 1710-1714.
-
(2015)
Ann Oncol
, vol.26
, pp. 1710-1714
-
-
Normanno, N.1
Rachiglio, A.M.2
Lambiase, M.3
-
2
-
-
84926512812
-
Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia
-
Paguirigan AL, Smith J, Meshinchi S et al. Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia. Sci Transl Med 2015; 7: 281re2.
-
(2015)
Sci Transl Med
, vol.7
-
-
Paguirigan, A.L.1
Smith, J.2
Meshinchi, S.3
-
3
-
-
84928254065
-
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution
-
McGranahan N, Favero F, de Bruin EC et al. Clonal status of actionable driver events and the timing of mutational processes in cancer evolution. Sci Transl Med 2015; 7: 283ra54.
-
(2015)
Sci Transl Med
, vol.7
-
-
McGranahan, N.1
Favero, F.2
de Bruin, E.C.3
-
4
-
-
84920285505
-
Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions
-
Brannon AR, Vakiani E, Sylvester BE et al. Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions. Genome Biol 2014; 15: 454.
-
(2014)
Genome Biol
, vol.15
, pp. 454
-
-
Brannon, A.R.1
Vakiani, E.2
Sylvester, B.E.3
-
5
-
-
84933040790
-
Clinical acquired resistance to RAF inhibitor combinations in BRAF-mutant colorectal cancer through MAPK pathway alterations
-
Ahronian LG, Sennott EM, Van Allen EM et al. Clinical acquired resistance to RAF inhibitor combinations in BRAF-mutant colorectal cancer through MAPK pathway alterations. Cancer Discov 2015; 5: 358-367.
-
(2015)
Cancer Discov
, vol.5
, pp. 358-367
-
-
Ahronian, L.G.1
Sennott, E.M.2
Van Allen, E.M.3
-
6
-
-
84876499616
-
Low incidence of minor BRAF V600 mutation-positive subclones in primary and metastatic melanoma determined by sensitive and quantitative real-time PCR
-
Kristensen T, Clemmensen O, Hoejberg L. Low incidence of minor BRAF V600 mutation-positive subclones in primary and metastatic melanoma determined by sensitive and quantitative real-time PCR. J Mol Diagn 2013; 15: 355-361.
-
(2013)
J Mol Diagn
, vol.15
, pp. 355-361
-
-
Kristensen, T.1
Clemmensen, O.2
Hoejberg, L.3
-
7
-
-
84905867190
-
High-sensitivity BRAF mutation analysis: BRAF V600E is acquired early during tumor development but is heterogeneously distributed in a subset of papillary thyroid carcinomas
-
de Biase D, Cesari V, Visani M et al. High-sensitivity BRAF mutation analysis: BRAF V600E is acquired early during tumor development but is heterogeneously distributed in a subset of papillary thyroid carcinomas. J Clin Endocrinol Metab 2014; 99: E1530-E1538.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. E1530-E1538
-
-
de Biase, D.1
Cesari, V.2
Visani, M.3
-
8
-
-
84923952286
-
A Big Bang model of human colorectal tumor growth
-
Sottoriva A, Kang H, Ma Z et al. A Big Bang model of human colorectal tumor growth. Nat Genet 2015; 47: 209-216.
-
(2015)
Nat Genet
, vol.47
, pp. 209-216
-
-
Sottoriva, A.1
Kang, H.2
Ma, Z.3
-
9
-
-
79960435101
-
Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer
-
Molinari F, Felicioni L, Buscarino M et al. Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer. Clin Cancer Res 2011; 17: 4901-4914.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4901-4914
-
-
Molinari, F.1
Felicioni, L.2
Buscarino, M.3
-
10
-
-
84877130883
-
Effect of low-frequency KRAS mutations on the response to anti-EGFR therapy in metastatic colorectal cancer
-
Tougeron D, Lecomte T, Pagès JC et al. Effect of low-frequency KRAS mutations on the response to anti-EGFR therapy in metastatic colorectal cancer. Ann Oncol 2013; 24: 1267-1273.
-
(2013)
Ann Oncol
, vol.24
, pp. 1267-1273
-
-
Tougeron, D.1
Lecomte, T.2
Pagès, J.C.3
-
11
-
-
84929463919
-
Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy
-
Laurent-Puig P, Pekin D, Normand C et al. Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy. Clin Cancer Res 2015; 21: 1087-1097.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 1087-1097
-
-
Laurent-Puig, P.1
Pekin, D.2
Normand, C.3
-
12
-
-
84925324704
-
Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer
-
Van Cutsem E, Lenz HJ, Köhne CH et al. Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer. J Clin Oncol 2015; 33: 692-700.
-
(2015)
J Clin Oncol
, vol.33
, pp. 692-700
-
-
Van Cutsem, E.1
Lenz, H.J.2
Köhne, C.H.3
-
13
-
-
84929141867
-
Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a metaanalysis of randomized, controlled trials
-
Sorich MJ, Wiese MD, Rowland A et al. Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a metaanalysis of randomized, controlled trials. Ann Oncol 2015; 26: 13-21.
-
(2015)
Ann Oncol
, vol.26
, pp. 13-21
-
-
Sorich, M.J.1
Wiese, M.D.2
Rowland, A.3
-
14
-
-
80051965827
-
Relative abundance of EGFR mutations predicts benefit from gefitinib treatment for advanced non-small-cell lung cancer
-
Zhou Q, Zhang XC, Chen ZH et al. Relative abundance of EGFR mutations predicts benefit from gefitinib treatment for advanced non-small-cell lung cancer. J Clin Oncol 2011; 29: 3316-3321.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3316-3321
-
-
Zhou, Q.1
Zhang, X.C.2
Chen, Z.H.3
-
15
-
-
84930586776
-
Mutant allele frequency predicts the efficacy of EGFR-TKIs in lung adenocarcinoma harboring the L858R mutation
-
Ono A, Kenmotsu H, Watanabe M et al. Mutant allele frequency predicts the efficacy of EGFR-TKIs in lung adenocarcinoma harboring the L858R mutation. Ann Oncol 2014; 25: 1948-1953.
-
(2014)
Ann Oncol
, vol.25
, pp. 1948-1953
-
-
Ono, A.1
Kenmotsu, H.2
Watanabe, M.3
-
16
-
-
84925337082
-
Expanded RAS: refining the patient population
-
Atreya CE, Corcoran RB, Kopetz S. Expanded RAS: refining the patient population. J Clin Oncol 2015; 33: 682-685.
-
(2015)
J Clin Oncol
, vol.33
, pp. 682-685
-
-
Atreya, C.E.1
Corcoran, R.B.2
Kopetz, S.3
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