Exosomal miRNAs from peritoneum lavage fluid as potential prognostic biomarkers of peritoneal metastasis in gastric cancer

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Tokuhisa, Motohiko ^a   Ichikawa, Yasushi ^a   Kosaka, Nobuyoshi ^b   Ochiya, Takahiro ^b   Yashiro, Masakazu ^c   Hirakawa, Kosei ^c   Kosaka, Takashi ^a   Makino, Hirochika ^a   Akiyama, Hirotoshi ^a   Kunisaki, Chikara ^a   Endo, Itaru ^a  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; MICRORNA 1202; MICRORNA 1207 5P; MICRORNA 1225 5P; MICRORNA 16; MICRORNA 21; MICRORNA 320C; MICRORNA 4270; UNCLASSIFIED DRUG; MIRN1225 MICRORNA, HUMAN; MIRN21 MICRORNA, HUMAN; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EARLY DIAGNOSIS; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MICROARRAY ANALYSIS; MIDDLE AGED; PERITONEUM LAVAGE; PERITONEUM METASTASIS; POLYMERASE CHAIN REACTION; RNA ANALYSIS; STOMACH CANCER; TUMOR VOLUME; VALIDATION PROCESS; VERY ELDERLY; ASCITES FLUID; DNA MICROARRAY; EXOSOME; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PERITONEUM TUMOR; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECONDARY; STOMACH NEOPLASMS; TUMOR CELL LINE; TUMOR RECURRENCE;

ADULT; AGED; AGED, 80 AND OVER; ASCITIC FLUID; BIOMARKERS, TUMOR; CELL LINE, TUMOR; EXOSOMES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICRORNAS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PERITONEAL LAVAGE; PERITONEAL NEOPLASMS; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS;

EID: 84941635969     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130472     Document Type: Article

References (33)

1. Carrington JC, Ambros V (2003) Role of microRNAs in plant and animal development. Science 301: 36-38. PMID: 12843372
2. Calin GA, Ferracin M, Cimmino A, Leva G, Shimizu M, Wojcik SE, et al. (2005) A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 353: 1793-1801. PMID: 16251535
3. Lorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, et al. (2005) MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65: 7065-7070. PMID: 16103053
4. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838. PMID: 15944708
5. Croce CM. (2009) Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet 10: 704-714. doi: 10.1038/nrg2634 PMID: 19763153
6. Kosaka N, Iguchi H, Yoshioka Y, Takeshita F, Matsuki Y, Ochiya T (2010) Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem 285: 1237-1248
7. Rabinowits G, Gercel-Taylor C, Day JM, Taylor DD, Kloecker GH (2009) Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer 10: 42-46. doi: 10.3816/CLC.2009.n.006 PMID: 19289371
8. Lawrie C, Gal S, Dunlop H, Pushkaran B, Liggins AP, Pulford K, et al. (2008) Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br J Haematol 141: 672-675. doi: 10.1111/j.1365-2141.2008.07077.x PMID: 18318758
9. Park N, Zhou H, Elashoff D, Henson B, Kastratovic D, Abemayor E, et al. (2009) Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection. Clin Cancer Res 15: 5473-5477 doi: 10.1158/1078-0432.CCR-09-0736 PMID: 19706812
10. Link A, Balaguer F, Shen Y, Nagasaka T, Lozano JJ, Boland CR, et al. (2010) Fecal MicroRNAs as Novel Biomarkers for Colon. Cancer Epidemiol, Biomarkers Prev 19: 1766-1774
11. Hanke M, Hoefig K, Merz H, Feller AC, Kausch I, Jocham D, et al. (2010) A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer. Urol Oncol 28: 655-661. doi: 10.1016/j.urolonc.2009.01.027 PMID: 19375957
12. Paoletti X, Oba K, Burzykowski T, Michiels S, Obashi Y, Pignon JP, et al. (2010) Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis. JAMA, J Am Med Assoc 303: 1729-1737
13. Keller S, Ridinger J, Rupp AK, Janssen JWG, Altevoqt P. (2011) Body fluid derived exosomes as a novel template for clinical diagnostics. J Transl Med 9 doi: 10.1186/1479-5876-9-86 PMID: 21651777
14. Yashiro M, Chung YS, Nishimura S, Inoue T, Sowa M (1996) Peritoneal metastatic model for human scirrhous gastric carcinoma in nude mice. Clin Exp Metastasis 14: 43-54. PMID: 8521616
15. Kosaka N, Iguchi H, Yoshioka Y, Hagiwara K, Takeshita F, Ochiya T. (2012) Competitive interactions of cancer cells and normal cells via secretory microRNAs. J Biol Chem 287: 1397-1405. doi: 10.1074/ jbc.M111.288662 PMID: 22123823
16. Maehara Y, Kabashima A, Tokunaga E, Hasuda S, Oki E, Baba H, et al. (1999) Recurrences and related characteristics of gastric cancer. Oncology 56: 322-327. PMID: 10343197
17. Tanaka Y, Kamohara H, Kinoshita K, Kurashige J, Ishimoto T, Iwatsuki M, et al. (2013) Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma. Cancer 119: 1159-1167. doi: 10.1002/cncr.27895 PMID: 23224754
18. Isobe Y, Nashimoto A, Akazawa K, Oda I, Hayashi K, Miyashiro I, et al. (2011) Gastric cancer treatment in Japan: 2008 annual report of the JGCA nationwide registry. Gastric Cancer 14: 301-316. doi: 1007/s10120-011-0085-6 PMID: 21894577
19. Lim JS, Yun MJ, Kim MJ, Hyung WJ, Park MS, Choi JY, et al. (2006) CT and PET in stomach cancer: preoperative staging and monitoring of response to therapy. Radiographics 26: 143-156. PMID: 16418249
20. Kim DW, Park SA, Kim CG. (2011) Detecting the recurrence of gastric cancer after curative resection: comparison of FDG PET/CT and contrast-enhanced abdominal CT. J Korean Med Sci 26: 875-880. doi: 10.3346/jkms.2011.26.7.875 PMID: 21738339
21. Bando E, Yonemura Y, Takeshita Y, Taniguchi K, Yasui T, Yoshimitsu Y, et al. (1999) Intraoperative lavage for cytological examination in 1,297 patients with gastric carcinoma. Am J Surg 178: 256-262. PMID: 10527450
22. Japanese Gastric Cancer Association. (2011) Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer 14: 101-112. doi: 10.1007/s10120-011-0041-5 PMID: 21573743
23. Tamura S, Fujiwara Y, Kimura Y, Fujita J, Imamura H, Kinuta M, et al. (2014) Prognostic information derived from RT-PCR analysis of peritoneal fluid in gastric cancer patients: Results from a prospective multicenter clinical trial. J Surg Oncol 109: 75-80. doi: 10.1002/jso.23472 PMID: 24155213
24. Lässer C, Alikhani VS, Ekström K, Eldh M, Paredes PT, Bossios A, et al. (2011) Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. J Transl Med 14: 9
25. Weber JA, Baxter DH, Zhang S, Huang DY, Huang KH, Lee MJ, et al. (2010) The microRNA spectrum in 12 body fluids. Clin Chem 56: 1733-1741. doi: 10.1373/clinchem.2010.147405 PMID: 20847327
26. Li QL, Bu N, Yu YC, Hua W, Xin XY. (2008) Ex vivo of experiments of human ovarian cancer ascitesderived exosomes presented by dendritic cells derived from umbilical cord blood for immunotherapy treatment. Clin Med: Oncol 2: 461-467
27. Levänen B, Bhakta N, Torregrossa P, Barbeau R, Hiltbrunner S, Pollack JL, et al. (2013) Altered micro- RNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients. J Allergy Clin Immunol 131: 894-903 doi: 10.1016/j.jaci.2012.11.039 PMID: 23333113
28. Liu J, Sun H, Wang X, Yu Q, Li S, Yu X, et al. (2014) Increased exosomal microRNA-21 and microRNA- 146a levels in the cervicovaginal lavage specimens of patients with cervical cancer. Int J Mol Sci 15: 758-773. doi: 10.3390/ijms15010758 PMID: 24406730
29. Fabbri M, Paone A, Calore F, Galli R, Gaudio E, Santhanam R, et al. (2012) MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response. Proc Natl Acad Sci U. S. A. 109: 2110-2116
30. Peinad H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, et al. (2012) Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med 18: 883-891. doi: 10.1038/nm.2753 PMID: 22635005
31. Sanyukta R, Kamilla M, Margot Z. (2013) Tumor microRNA modulates premetastatic organ cells. Neoplasia 15: 281-295. PMID: 23479506
32. Olszewski WL, Kubicka U, Tarnowski W, Bielecki K, Ziolkowska A, Wesolowska A. (2007) Activation of human peritoneal immune cells in early stages of gastric and colon cancer. Surgery 141: 212-221. PMID: 17263978
33. Li Z, Miao Z, Jin G, Li X, Li H, Lv Z, et al. (2012) βig-h3 supports gastric cancer cell adhesion, migration and proliferation in peritoneal carcinomatosis. Mol Med Rep 6: 558-564. doi: 10.3892/mmr.2012.951 PMID: 22710407