Medication adherence decision-making among adolescents and young adults with cancer

European Journal of Oncology Nursing

Volumn 20, Issue , 2015, Pages 207-214

  McGrady, Meghan E ^a   Brown, Gabriella A ^a   Pai, Ahna L H ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Adolescent; Decision making; Medication adherence; Young adult

Indexed keywords

ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT;

ADOLESCENT; ADULT; DECISION MAKING; FEMALE; HUMAN; MALE; MEDICATION COMPLIANCE; NEOPLASMS; ORAL DRUG ADMINISTRATION; PATIENT; PSYCHOLOGY; UNITED STATES; YOUNG ADULT;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; DECISION MAKING; FEMALE; HUMANS; MALE; MEDICATION ADHERENCE; MIDWESTERN UNITED STATES; NEOPLASMS; PATIENTS; YOUNG ADULT;

EID: 84941588045     PISSN: 14623889     EISSN: 15322122     Source Type: Journal    
DOI: 10.1016/j.ejon.2015.08.007     Document Type: Article

References (36)

1. Adolescent and Young Adults Oncology Progress Review Group Closing the Gap: Research and Care Imperatives for Adolescents and Young Adults with cancer 2006, available at:, (accessed 07.11.14.). http://planning.cancer.gov/library/AYAO_PRG_Report_2006_FINAL.pdf.
2. Amico K.R., Barta W., Konkle-Parker D.J., Fisher J.D., Cornman D.H., Shuper P.A., Fisher W.A. The information-motivation-behavioral skills model of ART adherence in a deep south HIV+ clinic sample. AIDS Behav. 2009, 13(1):66-75. 10.1007/s10461-007-9311-y.
3. Bhatia S., Landier W., Shangguan M., Hageman L., Schaible A.N., Carter A.R., et al. Nonadherence to oral mercaptopurine and risk of relapse in hispanic and non-hispanic white children with acute lymphoblastic leukemia: a report from the children's oncology group. J. Clin. Oncol. 2012, 30(17):2094-2101. 10.1200/jco.2011.38.9924.
4. Bleyer A. Latest estimates of survival rates of the 24 most common cancers in adolescent and young adult Americans. J. Adolesc. Young Adult Oncol. 2011, 1(1):37-42.
5. Bleyer A., O'Leary M., Barr R., Ries L. Cancer epidemiology in Older Adolescents and Young Adults 15 to 29 Years of Age, Including SEER Incidence and Survival: 1975-2000 2006, National Cancer Institute, Maryland, NIH Pub. No. 06-5767.
6. Bleyer W.A. Cancer in older adolescents and young adults: epidemiology, diagnosis, treatment, survival, and importance of clinical trials. Med. Pediatr. Oncol. 2002, 38(1):1-10.
7. Butow P., Palmer S., Pai A., Goodenough B., Luckett T., King M. Review of adherence-related issues in adolescents and young adults with cancer. J. Clin. Oncol. 2010, 28(32):4800-4809. 10.1200/jco.2009.22.2802.
8. Canner J., Alonzo T.A., Franklin J., Freyer D.R., Gamis A., Gerbing R.B. Differences in outcomes of newly diagnosed acute myeloid leukemia for adolescent/young adult and younger patients: a report from the children's oncology group. Cancer 2013, 119(23):4162-4169. 10.1002/cncr.28342.
9. Centers for Disease Control and Prevention, National Center for Health Statistics United States Cancer Statistics, 1999-2010 Mortality Request 2010, Available at:, (accessed 07/11/14.). http://wonder.cdc.gov/CancerMort-v2010.html.
10. Charmaz Grounded theory: objectivist and constructivist methods. Handbook of Qualitative Research 2000, Sage Publications, Inc, California. second ed. N.K. Denzin, Y.S. Lincoln (Eds.).
11. Corbin J., Strauss A. Basics of Qualitative Research: Techniques and Procedures for Developing Grounded Theory 2008, Sage Publications, Inc, California. third ed.
12. Diorio C., Tomlinson D., Boydell K.M., Regier D.A., Ethier M.C., Alli A., et al. Attitudes toward infection prophylaxis in pediatric oncology: a qualitative approach. PLoS One 2012, 7(10):e47815. 10.1371/journal.pone.0047815.
13. Dunne C. The place of the literature review in grounded theory research. Int. J. Soc. Res. Methodol. 2011, 14(2):111-124. 10.1080/13645579.2010.494930.
14. Festa R.S., Tamaroff M.H., Chasalow F., Lanzkowsky P. Therapeutic adherence to oral medication regimens by adolescents with cancer. I. Laboratory assessment. J. Pediatr. 1992, 120(5):807-811.
15. Fisher J.D., Fisher W.A., Amico K.R., Harman J.J. An information-motivation-behavioral skills model of adherence to antiretroviral therapy. Health Psychol. 2006, 25(4):462-473. 10.1037/0278-6133.25.4.462.
16. Holloway I., Todres L. The status of method: flexibility, consistency and coherence. Qual. Res. 2003, 3(3):345-357. 10.1177/1468794103033004.
17. Hullmann S.E., Brumley L.D., Schwartz L.A. Medical and psychosocial associates of nonadherence in adolescents with cancer. J. Pediatr. Oncol. Nurs. 2015, 32(2):103-113. 10.1177/1043454214553707.
18. Kato P.M., Cole S.W., Bradlyn A.S., Pollock B.H. A video game improves behavioral outcomes in adolescents and young adults with cancer: a randomized trial. Pediatrics 2008, 122(2):e305-317. 10.1542/peds.2007-3134.
19. Kennard B., Stewart S., Olvera R., Bawdon R., hAilin A., Lewis C., et al. Nonadherence in adolescent oncology patients: preliminary data on psychological risk factors and relationships to outcome. J. Clin. Psychol. Med. Sett. 2004, 11(1):31-39. 10.1023/B: JOCS.0000016267.21912.74.
20. Khamly K.K., Thursfield V.J., Fay M., Desai J., Toner G.C., Choong P.F., et al. Gender-specific activity of chemotherapy correlates with outcomes in chemosensitive cancers of young adulthood. Int. J. Cancer 2009, 125(2):426-431. 10.1002/ijc.24376.
21. Kok G., Schaalma H., Ruiter R.A.C., Van Empelen P., Brug J. Intervention mapping: a protocol for applying health psychology theory to prevention programmes. J. Health Psychol. 2004, 9(1):85-98. 10.1177/1359105304038379.
22. Komatsu H., Yagasaki K., Yoshimura K. Current nursing practice for patients on oral chemotherapy: a multicenter survey in Japan. BMC Res. Notes 2014, 7:259. 10.1186/1756-0500-7-259.
23. Kondryn H.J., Edmondson C.L., Hill J., Eden T.O.B. Treatment non-adherence in teenage and young adult patients with cancer. Lancet Oncol. 2011, 12:100-108. 10.1016/S1470-2045(10)70069-3.
24. Kottner J., Audige L., Brorson S., Donner A., Gajewski B.J., Hróbjartsson A., Roberts C., Shoukri M., Streiner D.L. Guidelines for reporting reliability and agreement studies were proposed. Int. J. Nurs. Stud. 2011, 49:661-671. 10.1016/j.ijnurstu.2011.01.016.
25. Morse The significance of saturation. Qual. Health Res. 1995, 5(2):147-149. 10.1177/104973239500500201.
26. National Cancer Institute at the National Institutes of Health A Snapshot of Adolescent and Young Adult Cancers 2013, available at:, (accessed: 07.11.14.). http://www.cancer.gov/researchandfunding/snapshots/adolescent-young-adult.
27. NVivo Qualitative Data Analysis Software (Version 10) 2012, QSR International Pty Ltd.
28. Quittner A.L., Modi A.C., Lemanek K.L., Ievers-Landis C.E., Rapoff M.A. Evidence-based assessment of adherence to medical treatments in pediatric psychology. J. Pediatr. Psychol. 2008, 33(9):916-936. discussion 937-918. 10.1093/jpepsy/jsm064.
29. Rohan J.M., Drotar D., Alderfer M., Donewar C.W., Ewing L., Katz E.R., Muriel A. Electronic monitoring of medication adherence in early maintenance phase treatment for pediatric leukemia nad lymphoma: identifying patterns of non-adherence. J. Pediatr. Psychol. 2015, 40(1):75-84. 10.1093/jpepsy/jst093.
30. Schwarzer Modeling health behavior change: how to predict and modify the adoption and maintenance of health behaviors. Appl. Psychol. 2008, 57(1):1-29. 10.1111/j.1464-0597.2007.00325.x.
31. Steinberg L., O'Brien L., Cauffman E., Graham S., Woolard J., Banich M. Age differences in future orientation and delay discounting. Child. Dev. 2009, 80(1):28-44.
32. Sung L., Alibhai S.M., Ethier M., Teuffel O., Cheng S., Fisman D., Regier D.A. Discrete choice experiment produced estimates of acceptable risks of therapeutic options in cancer patients with febrile neutropenia. J. Clin. Epidemiol. 2012, 65(6):627-634. 10.1016/j.jclinepi.2011.11.008.
33. Tebbi C.K., Cummings K.M., Zevon M.A., Smith L., Richards M., Mallon J. Compliance of pediatric and adolescent cancer patients. Cancer 1986, 58(5):1179-1184.
34. Wamboldt F.S., Bender B.G., Rankin A.E. Adolescent decision-making about use of inhaled asthma controller medication: results from focus groups with participants from a prior longitudinal study. J. Asthma 2011, 48(7):741-750. 10.3109/02770903.2011.598204.
35. Wu Y.P., Pai A.L. Health care provider-delivered adherence promotion interventions: a meta-analysis. Pediatrics 2014, 133(6):e1698-1707. 10.1542/peds.2013-3639.
36. Wysocki T., Harris M.A., Buckloh L.M., Mertlich D., Sobel Lochrie A., Taylor A., Sadler M., White N.H. Randomized, controlled trial of a behavioral family systems therapy for diabetes: maintenance and generalization of effects on parent-adolescent communication. Behav. Ther. 2008, 39:33-46. 10.1016/j.beth.2007.04.001.