MicroRNA-206: Effective inhibition of gastric cancer progression through the c-Met pathway

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Zheng, Zhiqiang ^a   Yan, Dongsheng ^a,b   Chen, Xiaoyan ^a,b   Huang, He ^a   Chen, Ke ^a   Li, Guangjing ^a,b   Zhou, Linglin ^a,b   Zheng, Dandan ^a,b   Tu, Lili ^a,b   Da Dong, Xiang ^c  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b State Key Laboratory Cultivation Base and Key Laboratory of Vision Science   (China)

^c Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 4; MICRORNA; MICRORNA 206; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; RETINOBLASTOMA PROTEIN; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; CDK4 PROTEIN, HUMAN; MAPK1 PROTEIN, HUMAN; MIRN206 MICRORNA, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMALL INTERFERING RNA;

AGS CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GASTRIC CANCER CELL LINE; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; TUMOR INVASION; UPREGULATION; WESTERN BLOTTING; ADENOCARCINOMA; ANIMAL; ANTAGONISTS AND INHIBITORS; CANCER TRANSPLANTATION; CELL MOTION; DISEASE COURSE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; STOMACH TUMOR; TUMOR VOLUME;

ADENOCARCINOMA; ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 4; DISEASE PROGRESSION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, NUDE; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASM TRANSPLANTATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MET; RETINOBLASTOMA PROTEIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TUMOR BURDEN;

EID: 84941366399     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0128751     Document Type: Article

References (21)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA: a cancer journal for clinicians. 2011; 61(2):69-90. doi: 10.3322/caac.20107 PMID: 21296855.
2. Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993; 75(5):843-54. PMID: 8252621.
3. Calin GA, Croce CM. MicroRNA signatures in human cancers. Nature reviews Cancer. 2006; 6 (11):857-66. doi: 10.1038/nrc1997 PMID: 17060945.
4. He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nature reviews Genetics. 2004; 5(7):522-31. doi: 10.1038/nrg1379 PMID: 15211354.
5. Gommans WM, Berezikov E. Controlling miRNA regulation in disease. Methods in molecular biology. 2012; 822:1-18. doi: 10.1007/978-1-61779-427-8-1 PMID: 22144188.
6. Xu X, Yang X, Xing C, Zhang S, Cao J. miRNA: The nemesis of gastric cancer (Review). Oncology letters. 2013; 6(3):631-41. doi: 10.3892/ol.2013.1428 PMID: 24137382; PubMed Central PMCID: PMC3789097.
7. Shrestha S, Hsu SD, Huang WY, Huang HY, Chen W, Weng SL, et al. A systematic review of micro- RNA expression profiling studies in human gastric cancer. Cancer medicine. 2014; 3(4):878-88. doi: 10.1002/cam4.246 PMID: 24902858.
8. Ren J, Huang HJ, Gong Y, Yue S, Tang LM, Cheng SY. MicroRNA-206 suppresses gastric cancer cell growth and metastasis. Cell & bioscience. 2014; 4:26. doi: 10.1186/2045-3701-4-26 PMID: 24855559; PubMed Central PMCID: PMC4030529.
9. Yan D, Dong Xda E, Chen X, Wang L, Lu C, Wang J, et al. MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. The Journal of biological chemistry. 2009; 284(43):29596-604. doi: 10.1074/jbc.M109.020511 PMID: 19710019; PubMed Central PMCID: PMC2785592.
10. Zhang L, Liu X, Jin H, Guo X, Xia L, Chen Z, et al. miR-206 inhibits gastric cancer proliferation in part by repressing cyclinD2. Cancer letters. 2013; 332(1):94-101. doi: 10.1016/j.canlet.2013.01.023 PMID: 23348698.
11. Peng Z, Zhu Y, Wang Q, Gao J, Li Y, Li Y, et al. Prognostic significance of MET amplification and expression in gastric cancer: a systematic review with meta-analysis. PloS one. 2014; 9(1):e84502. doi: 10.1371/journal.pone.0084502 PMID: 24416238; PubMed Central PMCID: PMC3885582.
12. Yan D, Zhou X, Chen X, Hu DN, Dong XD, Wang J, et al. MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met. Investigative ophthalmology & visual science. 2009; 50(4):1559-65. doi: 10.1167/iovs.08-2681 PMID: 19029026.
13. Ueda T, Volinia S, Okumura H, Shimizu M, Taccioli C, Rossi S, et al. Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. The Lancet Oncology. 2010; 11(2):136-46. doi: 10.1016/S1470-2045(09)70343-2 PMID: 20022810.
14. Zeng Z, Wang J, Zhao L, Hu P, Zhang H, Tang X, et al. Potential role of microRNA-21 in the diagnosis of gastric cancer: a meta-analysis. PloS one. 2013; 8(9):e73278. doi: 10.1371/journal.pone.0073278 PMID: 24023850; PubMed Central PMCID: PMC3762732.
15. He XP, Shao Y, Li XL, Xu W, Chen GS, Sun HH, et al. Downregulation of miR-101 in gastric cancer correlates with cyclooxygenase-2 overexpression and tumor growth. The FEBS journal. 2012; 279 (22):4201-12. doi: 10.1111/febs.12013 PMID: 23013439.
16. Oh HK, Tan AL, Das K, Ooi CH, Deng NT, Tan IB, et al. Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer. Clinical cancer research: an official journal of the American Association for Cancer Research. 2011; 17(9):2657-67. doi: 10.1158/1078-0432. CCR-10-3152 PMID: 21415212.
17. Huang TJ, Wang JY, Lin SR, Lian ST, Hsieh JS. Overexpression of the c-met protooncogene in human gastric carcinoma-correlation to clinical features. Acta oncologica. 2001; 40(5):638-43. PMID: 11669338.
18. Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF. Met, metastasis, motility and more. Nature reviews Molecular cell biology. 2003; 4(12):915-25. doi: 10.1038/nrm1261 PMID: 14685170.
19. Sotoudeh K, Hashemi F, Madjd Z, Sadeghipour A, Molanaei S, Kalantary E. The clinicopathologic association of c-MET overexpression in Iranian gastric carcinomas; an immunohistochemical study of tissue microarrays. Diagnostic pathology. 2012; 7:57. doi: 10.1186/1746-1596-7-57 PMID: 22640970; PubMed Central PMCID: PMC3408322.
20. Parasramka MA, Dashwood WM, Wang R, Saeed HH, Williams DE, Ho E, et al. A role for low-abundance miRNAs in colon cancer: the miR-206/Kruppel-like factor 4 (KLF4) axis. Clinical epigenetics. 2012; 4(1):16. doi: 10.1186/1868-7083-4-16 PMID: 23006636; PubMed Central PMCID: PMC3506528.
21. Naito S, von Eschenbach AC, Giavazzi R, Fidler IJ. Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice. Cancer research. 1986; 46 (8):4109-15. PMID: 3731078.