Mutations causing complex disease may under certain circumstances be protective in an epidemiological sense

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Siegert, Sabine ^a,b   Wolf, Andreas ^b   Cooper, David N ^c   Krawczak, Michael ^b   Nothnagel, Michael ^a,b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DISEASES; GENEALOGY; GENETIC ASSOCIATION; GENETIC EPIDEMIOLOGY; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; MUTATION; MUTATION RATE; PANDEMIC; PREVALENCE; RARE DISEASE; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGICAL MODEL; EPIDEMIOLOGY; GENE LOCUS; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; PENETRANCE; PHYLOGENY; RISK FACTOR;

EPIDEMIOLOGY; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MODELS, GENETIC; MUTATION; PENETRANCE; PHYLOGENY; RISK FACTORS;

EID: 84941361855     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132150     Document Type: Article

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