Sleep apnea is not associated with worse outcomes in kidney transplant recipients

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Fornadi, Katalin ^a   Ronai, Katalin Zsuzsanna ^b   Turanyi, Csilla Zita ^b   Malavade, Tushar S ^c   Shapiro, Colin Michael ^c   Novak, Marta ^b,c   Mucsi, Istvan ^b,c   Molnar, Miklos Z ^d  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; COMPLICATION; FEMALE; GLOMERULUS FILTRATION RATE; GRAFT RECIPIENT; HUMAN; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; MORTALITY; PATHOLOGY; POLYSOMNOGRAPHY; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RENAL INSUFFICIENCY, CHRONIC; RISK FACTOR; SLEEP APNEA, OBSTRUCTIVE; SURVIVAL; TREATMENT OUTCOME;

ADULT; AGED; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; POLYSOMNOGRAPHY; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RENAL INSUFFICIENCY, CHRONIC; RISK FACTORS; SLEEP APNEA, OBSTRUCTIVE; SURVIVAL ANALYSIS; TRANSPLANT RECIPIENTS; TREATMENT OUTCOME;

EID: 84941352871     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep06987     Document Type: Article

References (38)

1. Young, T. et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328, 1230-1235 (1993).
2. Young, T. et al. Sleep Disordered Breathing and Mortality: Eighteen-Year Followup of the Wisconsin Sleep Cohort. Sleep 31, 1071-1078 (2008).
3. Marshall, N. S. et al. Sleep Apnea as an Independent Risk Factor for All-Cause Mortality: The Busselton Health Study. Sleep 31, 1079-1085 (2008).
4. Kim, H. C. et al. Sleep-disordered breathing and neuropsychological deficits. A population-based study. Am J Respir Crit Care Med 156, 1813-1819 (1997).
5. Reichmuth, K. J., Austin, D., Skatrud, J. B. & Young, T. Association of sleep apnea and type II diabetes: a population-based study. Am J Respir Crit Care Med 172, 1590-1595 (2005).
6. Dunai, A. et al. Cardiovascular disease and health-care utilization in snorers: a population survey. Sleep 31, 411-416 (2008).
7. Yaggi, H. K. et al. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med 353, 2034-2041 (2005).
8. Kuhlmann, U. et al. Sleep-apnea in patients with end-stage renal disease and objective results. Clin Nephrol 53, 460-466 (2000).
9. Markou, N. et al. Sleep-disordered breathing in nondialyzed patients with chronic renal failure. Lung 184, 43-49 (2006).
10. Unruh, M. L. et al. Sleep apnea in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the Sleep Heart Health Study. J Am Soc Nephrol 17, 3503-3509 (2006).
11. Molnar, M. Z. et al. Sleep apnea is associated with cardiovascular risk factors among kidney transplant patients. Clin J AmSoc Nephrol 5, 125-132, doi:10.2215/CJN.04030609 (2010).
12. Mallamaci, F. et al. Sleep disordered breathing in renal transplant patients. Am J Transplant 9, 1373-1381, doi:10.1111/j.1600-6143.2009.02653.x (2009).
13. de Oliveira Rodrigues, C. J. et al. Relationship among end-stage renal disease, hypertension, and sleep apnea in nondiabetic dialysis patients.AmJHypertens 18, 152-157, doi:10.1016/j.amjhyper.2004.08.028 (2005).
14. Kinebuchi, S. et al. Short-term use of continuous positive airway pressure ameliorates glomerular hyperfiltration in patients with obstructive sleep apnoea syndrome. Clin Sci (Lond) 107, 317-322, doi:10.1042/CS20040074 (2004).
15. Nicholl, D. D. et al. Declining kidney function increases the prevalence of sleep apnea and nocturnal hypoxia. Chest 141, 1422-1430, doi:10.1378/chest.11-1809 (2012).
16. Mirrakhimov, A. E. Decreased renal function and the prevalence of obstructive sleep apnea: more data are needed. Chest 142, 1076; author reply 1076-1077, doi:10.1378/chest.12-1410 (2012).
17. Yumino, D. et al. Nocturnal rostral fluid shift: a unifying concept for the pathogenesis of obstructive and central sleep apnea in men with heart failure. Circulation 121, 1598-1605, doi:10.1161/CIRCULATIONAHA.109.902452 (2010).
18. Friedman, O., Bradley, T. D., Chan, C. T., Parkes, R. & Logan, A. G. Relationship between overnight rostral fluid shift and obstructive sleep apnea in drug-resistant hypertension. Hypertension 56, 1077-1082, doi:10.1161/ HYPERTENSIONAHA.110.154427 (2010).
19. Witkowski, A. et al. Effects of renal sympathetic denervation on blood pressure, sleep apnea course, and glycemic control in patients with resistant hypertension and sleep apnea. Hypertension 58, 559-565, doi:10.1161/ HYPERTENSIONAHA.111.173799 (2011).
20. Tsioufis, C., Papademetriou, V., Thomopoulos, C. & Stefanadis, C. Renal denervation for sleep apnea and resistant hypertension: alternative or complementary to effective continuous positive airway pressure treatment? Hypertension 58, e191; author reply e192, doi:10.1161/ HYPERTENSIONAHA.111.181479 (2011).
21. Szentkiralyi, A. et al. High risk of obstructive sleep apnea is a risk factor of death censored graft loss in kidney transplant recipients: an observational cohort study. Sleep Med 12, 267-273, doi:10.1016/j.sleep.2010.08.012 (2011).
22. Cirignotta, F. et al. Reliability of a questionnaire screening restless legs syndrome in patients on chronic dialysis. Am J Kidney Dis 40, 302-306, doi:10.1053/ ajkd.2002.34508 (2002).
23. Zoccali, C., Mallamaci, F. & Tripepi, G. Nocturnal hypoxemia predicts incident cardiovascular complications in dialysis patients. J Am Soc Nephrol 13, 729-733 (2002).
24. Masuda, T. et al. Sleep-disordered breathing predicts cardiovascular events and mortality in hemodialysis patients. Nephrol Dial Transplant 26, 2289-2295, doi:10.1093/ndt/gfq756 (2011).
25. Ronai, K. Z. et al. Obstructive sleep apnea without excessive daytime sleepiness in kidney transplant recipients. Sleep 36 (abstract supplement), A153 (2013).
26. Roumelioti, M. E. et al. Sleep-disordered breathing and excessive daytime sleepiness in chronic kidney disease and hemodialysis. Clin J Am Soc Nephrol 6, 986-994, doi:10.2215/CJN.05720710 (2011).
27. Gooneratne, N. S. et al. Sleep disordered breathing with excessive daytime sleepiness is a risk factor for mortality in older adults. Sleep 34, 435-442 (2011).
28. Lindberg, E., Berne, C., Franklin, K. A., Svensson, M. & Janson, C. Snoring and daytime sleepiness as risk factors for hypertension and diabetes in women-a population-based study. Respir Med 101, 1283-1290, doi:10.1016/j.rmed.2006.10.015 (2007).
29. Kapur, V. K., Resnick, H. E., Gottlieb, D. J. & Sleep Heart Health Study, G. Sleep disordered breathing and hypertension: does self-reported sleepiness modify the association? Sleep 31, 1127-1132 (2008).
30. Feng, J., He,Q. Y., Zhang, X. L., Chen, B. Y.&Sleep Breath Disorder Group, S. o. R. M. Epworth Sleepiness Scale may be an indicator for blood pressure profile and prevalence of coronary artery disease and cerebrovascular disease in patients with obstructive sleep apnea. Sleep Breath 16, 31-40, doi:10.1007/s11325-011-0481-5 (2012).
31. Unruh, M. L. et al. Subjective and objective sleep quality in patients on conventional thrice-weekly hemodialysis: comparison with matched controls from the sleep heart health study. Am J Kidney Dis 52, 305-313 (2008).
32. Rechtschaffen, A.&Kales, A. (Brain Information Service/Brain Research Institute, University of California at Los Angeles, CA, USA, 1968).
33. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep 22, 667-689 (1999).
34. Nakashima, H. et al. Obstructive sleep apnoea inhibits the recovery of left ventricular function in patients with acute myocardial infarction. Eur Heart J 27, 2317-2322 (2006).
35. Hanly, P. J. & Pierratos, A. Improvement of sleep apnea in patients with chronic renal failure who undergo nocturnal hemodialysis. N Engl J Med 344, 102-107 (2001).
36. Levey AS, G. T., Kusek, J. W. et al. A simplified equation to predict glomerular filtration rate from serum creatinine (Abstr). J Am Soc Nephrol 11, 155A (2000).
37. Charlson, M. E., Pompei, P., Ales, K. L. & MacKenzie, C. R. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40, 373-383 (1987).
38. Jassal, S. V., Schaubel, D. E. & Fenton, S. S. Baseline comorbidity in kidney transplant recipients: a comparison of comorbidity indices. Am J Kidney Dis 46, 136-142 (2005).