Histologic analysis of retrieved clots in acute ischemic stroke: Correlation with stroke etiology and gradient-echo MRI

American Journal of Neuroradiology

Volumn 36, Issue 9, 2015, Pages 1756-1762

  Kim, S K ^a   Yoon, W ^a   Kim, T S ^a   Kim, H S ^a   Heo, T W ^a   Park, M S ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRIN;

ADULT; AGED; ARTICLE; ATRIAL FIBRILLATION; BLOOD CLOT; BRAIN ANGIOGRAPHY; BRAIN ATHEROSCLEROSIS; BRAIN ISCHEMIA; CARDIOEMBOLIC STROKE; CAROTID ARTERY STENTING; CEREBRAL REVASCULARIZATION; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DYSLIPIDEMIA; ENDOVASCULAR SURGERY; ERYTHROCYTE; FEMALE; GRADIENT ECHO NUCLEAR MAGNETIC RESONANCE IMAGING; HISTOPATHOLOGY; HUMAN; HYPERTENSION; LEUKOCYTE; MALE; MECHANICAL THROMBECTOMY; MIDDLE CEREBRAL ARTERY OCCLUSION; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NUCLEAR MAGNETIC RESONANCE IMAGING; SMOKING; THROMBOCYTE; THROMBUS ASPIRATION; VERY ELDERLY; ATHEROSCLEROSIS; COMPLICATION; HEART DISEASE; INTRACRANIAL EMBOLISM; MIDDLE AGED; PATHOLOGY; PROCEDURES; STROKE;

AGED; AGED, 80 AND OVER; ATHEROSCLEROSIS; BLOOD PLATELETS; ERYTHROCYTES; FEMALE; FIBRIN; HEART DISEASES; HUMANS; INTRACRANIAL EMBOLISM; LEUKOCYTES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; STROKE;

EID: 84941340808     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A4402     Document Type: Article

References (20)

1. Saver JL, Jahan R, Levy EI, et al; SWIFT Trialists. Solitaire flow restoration device versus the Merci retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial. Lancet 2012;380:1241-49
2. Nogueira RG, Lutsep HL, Gupta R, et al; TREVO 2 Trialists. Trevo versus Merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial. Lancet 2012;380:1231-40
3. Pereira VM, Gralla J, Davalos A, et al. Prospective, multicenter, single-arm study of mechanical thrombectomy using Solitaire Flow Restoration in acute ischemic stroke. Stroke 2013;44:2802-07
4. Turk AS, Frei D, Fiorella D, et al. ADAPT FAST study: a direct aspiration first pass technique for acute stroke thrombectomy. J Neurointerv Surg 2014;6:260-64
5. Kim SK, Yoon W, Moon SM, et al. Outcomes of manual aspiration thrombectomy for acute ischemic stroke refractory to stent-based thrombectomy. J Neurointerv Surg 2015;7:473-77
6. Marder VJ, Chute DJ, Starkman S, et al. Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke 2006;37:2086-93
7. Mehta BP, Nogueira RG. Should clot composition affect choice of endovascular therapy? Neurology 2012;79(suppl 1):S63-67
8. Niesten JM, van der Schaaf IC, van Dam L, et al. Histopathologic composition of cerebral thrombi of acute stroke patients is correlated with stroke subtype and thrombus attenuation. PLoS One 2014;9:e88882
9. Boeckh-Behrens T, Schubert M, Förschler A, et al. The impact of histological clot composition in embolic stroke. Clin Neuroradiol 2014 Sep 27. [Epub ahead of print]
10. Liebeskind DS, Sanossian N, YongWH,et al. CTandMRIearly vessel signs reflect clot composition in acute stroke. Stroke 2011;42: 1237-43
11. Simons N, Mitchell P, Dowling R, et al. Thrombus composition in acute ischemic stroke: a histopathological study of thrombus extracted by endovascular retrieval. J Neuroradiol 2015;42:86-92
12. Viereck J, Ruberg FL, Qiao Y, et al. MRI of atherothrombosis associated with plaque rupture. Arterioscler Thromb Vasc Biol 2005;25: 240-45
13. Adams HP Jr, Bendixen BH, Kappelle LJ, et al; TOAST Investigators. Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial. Stroke 1993;24:35-41
14. Yoon W, Jung MY, Jung SH, et al. Subarachnoid hemorrhage in a multimodal approach heavily weighted toward mechanical thrombectomy with Solitaire stent in acute stroke. Stroke 2013;44:414-19
15. Zaidat OO, Yoo AJ, Khatri P, et al; Cerebral Angiographic Revascularization Grading (CARG) Collaborators, STIR Revascularization working group, STIR Thrombolysis in Cerebral Infarction (TICI) Task Force. Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke 2013;44:2650-63
16. Rovira A, Orellana P, Alvarez-Sabin J, et al. Hyperacute ischemic stroke: middle cerebral artery susceptibility sign at echo-planar gradient-echo MR imaging. Radiology 2004;232:466-73
17. Cho KH, Kim JS, Kwon SU, et al. Significance of susceptibility vessel sign on T2-weighted gradient echo imaging for identification of stroke subtypes. Stroke 2005;36:2379-83
18. Sato Y, Ishibashi-Ueda H, Iwakiri T, et al. Thrombus components in cardioembolic and atherothrombotic strokes. Thromb Res 2012; 130:278-80
19. Sato Y, Hatakeyama K, Yamashita A, et al. Proportion of fibrin and platelets differs in thrombi on ruptured and eroded coronary atherosclerotic plaques in humans. Heart 2005;91:526-30
20. Patel MR, Edelman RR, Warach S. Detection of hyperacute primary intraparenchymal hemorrhage by magnetic resonance imaging. Stroke 1996;27:2321-24