Respiratory viruses associated with communityacquired pneumonia in children: Matched case-control study

Thorax

Volumn 70, Issue 9, 2015, Pages 847-853

  Rhedin, Samuel ^a   Lindstrand, Ann ^b,c   Hjelmgren, Annie ^a   Ryd Rinder, Malin ^c   Öhrmalm, Lars ^a   Tolfvenstam, Thomas ^a,b   Örtqvist, Åke ^a,d   Rotzén Östlund, Maria ^a,c   Zweygberg Wirgart, Benita ^a,c   Henriques Normark, Birgitta ^a,c   Broliden, Kristina ^a   Naucler, Pontus ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d STOCKHOLM COUNTY COUNCIL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CASE CONTROL STUDY; CHILD; CHILD HEALTH CARE; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; INFANT; INFLUENZA; INFLUENZA VIRUS; MAJOR CLINICAL STUDY; MALE; METAPNEUMOVIRUS; METAPNEUMOVIRUS INFECTION; MIXED INFECTION; NASOPHARYNGEAL ASPIRATION; NONHUMAN; ONSET AGE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY VIRUS; RETROSPECTIVE STUDY; SWEDEN; VIRUS DETECTION; COMMUNITY ACQUIRED INFECTION; EPIDEMIOLOGY; PRESCHOOL CHILD; VIROLOGY; VIRUS PNEUMONIA;

CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HUMANS; INFANT; MALE; PNEUMONIA, VIRAL; REAL-TIME POLYMERASE CHAIN REACTION; SWEDEN;

EID: 84941335994     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2015-206933     Document Type: Article

References (35)

1. Walker CL, Rudan I, Liu L, et al. Global burden of childhood pneumonia and diarrhoea. Lancet 2013;381:1405-16.
2. Ruuskanen O, Lahti E, Jennings LC, et al. Viral pneumonia. Lancet 2011;377:1264-75.
3. Jain S, Williams DJ, Arnold SR, et al. Community-acquired pneumonia requiring hospitalization among US children. N Engl J Med 2015;372:835-45.
4. Lindstrand A, Bennet R, Galanis I, et al. Sinusitis and pneumonia hospitalization after introduction of pneumococcal conjugate vaccine. Pediatrics 2014;134: E1526-36.
5. Berkley JA, Munywoki P, Ngama M, et al. Viral etiology of severe pneumonia among Kenyan infants and children. JAMA 2010;303:2051-7.
6. Fry AM, Lu X, Chittaganpitch M, et al. Human bocavirus: A novel parvovirus epidemiologically associated with pneumonia requiring hospitalization in Thailand. J Infect Dis 2007;195:1038-45.
7. Mathisen M, Strand TA, Valentiner-Branth P, et al. Respiratory viruses in nepalese children with and without pneumonia: A case-control study. Pediatr Infect Dis J 2010;29:731-5.
8. Singleton RJ, Bulkow LR, Miernyk K, et al. Viral respiratory infections in hospitalized and community control children in Alaska. J Med Virol 2010;82:1282-90.
9. Wolf DG, Greenberg D, Shemer-Avni Y, et al. Association of human metapneumovirus with radiologically diagnosed community-acquired alveolar pneumonia in young children. J Pediatr 2010;156:115-20.
10. Wingerter SL, Bachur RG, Monuteaux MC, et al. Application of the world health organization criteria to predict radiographic pneumonia in a US-based pediatric emergency department. Pediatr Infect Dis J 2012;31:561-4.
11. Cherian T, Mulholland EK, Carlin JB, et al. Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies. Bull World Health Organ 2005;83:353-9.
12. Jartti T, Söderlund-Venermo M, Hedman K, et al. New molecular virus detection methods and their clinical value in lower respiratory tract infections in children. Paediatr Respir Rev 2013;14:38-45.
13. Rhedin S, Lindstrand A, Rotzén-Östlund M, et al. Clinical utility of PCR for common viruses in acute respiratory illness. Pediatrics 2014;133:e538-45.
14. Martin H, Frenzel L, Fassih N, et al. Barnhälsovård - Annual report by Stockholm County Child Health Centers. 2013.
15. International Child Health Review Collaboration. Pocket book of hospital care for children. 2nd edn. Geneva: World Health Organization, 2013.
16. Reed C, Madhi SA, Klugman KP, et al. Development of the Respiratory Index of Severity in Children (RISC) score among young children with respiratory infections in South Africa. PLoS ONE 2012;7:e27793.
17. Wikland KA, Luo ZC, Niklasson A, et al. Swedish population-based longitudinal reference values from birth to 18 years of age for height, weight and head circumference. Acta Paediatr 2002;91:739-54.
18. Tiveljung-Lindell A, Rotzén-Ostlund M, Gupta S, et al. Development and implementation of a molecular diagnostic platform for daily rapid detection of 15 respiratory viruses. J Med Virol 2009;81:167-75.
19. Nijhuis M, van Maarseveen N, Schuurman R, et al. Rapid and sensitive routine detection of all members of the genus enterovirus in different clinical specimens by real-time PCR. J Clin Microbiol 2002;40:3666-70.
20. Edwards KM, Zhu Y, Griffin MR, et al. Burden of human metapneumovirus infection in young children. N Engl J Med 2013;368:633-43.
21. Panda S, Mohakud NK, Pena L, et al. Human metapneumovirus: Review of an important respiratory pathogen. Int J Infect Dis 2014;25:45-52.
22. Williams J, Halburnt-rush LL, Ed M, et al. Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med 2004;250:443-50.
23. Kuiken T, van den Hoogen BG, van Riel D J, et al. Experimental human metapneumovirus infection of cynomolgus macaques (Macaca fascicularis) results in virus replication in ciliated epithelial cells and pneumocytes with associated lesions throughout the respiratory tract. Am J Pathol 2004;164:1893-900.
24. Virkki R, Juven T, Rikalainen H, et al. Differentiation of bacterial and viral pneumonia in children. Thorax 2002;57:438-41.
25. Deloria-Knoll M, Feikin DR, Scott JA, et al. Identification and selection of cases and controls in the Pneumonia Etiology Research for Child Health project. Clin Infect Dis 2012;54(Suppl 2):S117-23.
26. Martin ET, Fairchok MP, Kuypers J, et al. Frequent and prolonged shedding of bocavirus in young children attending daycare. J Infect Dis 2010;201: 1625-32.
27. Cowling BJ, Fang VJ, Nishiura H, et al. Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine. Clin Infect Dis 2012;54:1778-83.
28. Kalu SU, Loeffelholz M, Beck E, et al. Persistence of adenovirus nucleic acids in nasopharyngeal secretions: A diagnostic conundrum. Pediatr Infect Dis J 2010;29:746-50.
29. Do Carmo Debur M, Raboni SM, Flizikowski FBZ, et al. Immunohistochemical assessment of respiratory viruses in necropsy samples from lethal non-pandemic seasonal respiratory infections. J Clin Pathol 2010;63:930-4.
30. Juven T, Mertsola J, Waris M, et al. Etiology of community-acquired pneumonia in 254 hospitalized children. Pediatr Infect Dis J 2000;19:293-8.
31. Bogaert D, De Groot R, Hermans PWM. Streptococcus pneumoniae colonisation: The key to pneumococcal disease. Lancet Infect Dis 2004;4:144-54.
32. Weinberger DM, Klugman KP, Steiner C, et al. Association between respiratory syncytial virus activity and pneumococcal disease in infants: A time series analysis of US hospitalization data. PLoS Med 2015;12:e1001776.
33. Kukavica-Ibrulj I, Hamelin M-E, Prince G a, et al. Infection with human metapneumovirus predisposes mice to severe pneumococcal pneumonia. J Virol 2009;83:1341-9.
34. Madhi S, Ludewick H. Pneumococcal coinfection with human metapneumovirus. J Infect Dis 2006;193:1236-43.
35. Howie SR, Morris GA, Tokarz R, et al. Etiology of severe childhood pneumonia in the Gambia, west Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples. Clin Infect Dis 2014;59:682-5.