Cardiac catheterization in mice to measure the pressure volume relationship: Investigating the Bowditch effect

Journal of Visualized Experiments

Volumn 2015, Issue 100, 2015, Pages

  Zhang, Bo ^a,b   Davis, Jonathan P ^a   Ziolo, Mark T ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Catheterization; Contractility; End systolic pressure volume relationship; Issue 100; Medicine; Murine; NOS1; Preload recruitable stroke work; PV loops

Indexed keywords

NEURONAL NITRIC OXIDE SYNTHASE; NOS1 PROTEIN, MOUSE;

ANIMAL; ANIMAL MODEL; DEFICIENCY; HEART; HEART CATHETERIZATION; HEART LEFT VENTRICLE FUNCTION; HEART RATE; KNOCKOUT MOUSE; MOUSE; PHYSIOLOGY; PROCEDURES;

ANIMALS; CARDIAC CATHETERIZATION; HEART; HEART RATE; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; NITRIC OXIDE SYNTHASE TYPE I; VENTRICULAR FUNCTION, LEFT;

EID: 84941248063     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/52618     Document Type: Article

References (10)

1. Janssen, P. M. Myocardial contraction-relaxation coupling. Am J Physiol Heart Circ Physiol. 299, H1741-H1749 (2010).
2. Roman, M. J., Devereux, R. B. Comparison of noninvasive measures of contractility in dilated cardiomyopathy. Echocardiography. 8, 139-150 (1991).
3. Hamlin, R. L., del Rio, C. dP/dt(max)--a measure of 'baroinometry. J Pharmacol Toxicol Methods. 66, 63-65 (2012).
4. Feneley, M. P., et al. Comparison of preload recruitable stroke work, end-systolic pressure-volume and dP/dtmax-end-diastolic volume relations as indexes of left ventricular contractile performance in patients undergoing routine cardiac catheterization. J Am Coll Cardiol. 19, 1522-1530 (1992).
5. Kass, D. A., et al. Comparative influence of load versus inotropic states on indexes of ventricular contractility: experimental and theoretical analysis based on pressure-volume relationships. Circulation. 76, 1422-1436 (1987).
6. Nemoto, S., DeFreitas, G., Mann, D. L., Carabello, B. A. Effects of changes in left ventricular contractility on indexes of contractility in mice. Am J Physiol Heart Circ Physiol. 283, H2504-H2510 (2002).
7. Ziolo, M. T., Kohr, M. J., Wang, H. Nitric oxide signaling and the regulation of myocardial function. J Mol Cell Cardiol. 45, 625-632 (2008).
8. Barouch, L. A., et al. Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature. 416, 337-339 (2002).
9. Wang, H., et al. Neuronal nitric oxide synthase signaling within cardiac myocytes targets phospholamban. Am J Physiol Cell Physiol. 294, C1566-C1575 (2008).
10. Georgakopoulos, D., et al. In vivo murine left ventricular pressure-volume relations by miniaturized conductance micromanometry. Am J Physiol. 274, H1416-H1422 (1998).