Outcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: A prospective multicenter study

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 29, Issue 13, 2016, Pages 2186-2193

  Alan, Serdar ^a   Erdeve, Omer ^b   Cakir, Ufuk ^b   Akduman, Hasan ^b   Zenciroglu, Aysegul ^c   Akcakus, Mustafa ^d   Tunc, Turan ^e   Gokmen, Zeynel ^f   Ates, Can ^b   Atasay, Begum ^b   Arsan, Saadet ^b   Anik, A ^g   Turkmen, M K ^g   Erdogan, Y ^d   Oygur, N ^d   Kahvecioglu, D ^b   Yildiz, D ^b   Caner, I ^h   Tekgunduz, K S ^h   Kurt, A ⁱ   Yigit, Y ^j   Bilgili, G ^j   Bolat, F ^k   Cevit, O ^k   Ozlu, F ^l   Satar, M ^l   Ertugrul, S ^m   Cakir, B ⁿ   Unal, S ⁿ   Iscan, B ^o   Duman, N ^o   Ergor, S N ^p   Yalaz, M ^p   Celik, I ^q   Celik, U ^q   Hirfanoglu, I M ^r   Koc, E ^r   Sivasli, E ^s   Melekoglu, N A ^s   Kiray Bas, E ^t   Bozkaya, D ^u   Korkmaz, A ^u   Ozdemir, R ^v   Karadag, A ^v   Ozer, E ^w   Ilhan, O ^w   Mutlu, M ^x   Aslan, Y ^x   Erener Ercan, T ^y   Cetinkaya, M ^y   Sahin, O ^z   Akin, M A ^z   Okumus, N ^c   Demirel, G ^aa   Kilic, A ^aa   Turkoglu Unal, E ^ab   Bulbul, A ^ab   Takci, S ^ac   Anuk Ince, D ^ac   Ciftdemir, N A ^ad   Acunas, B ^ad   Ozkan, H ^ae   Koksal, N ^ae   Okulu, E ^af   Demir, N ^ag   Tuncer, O ^ag   Dizdar, E A ^ah   Oguz, S ^ah   Dilmen, U ^ah   more..

^a HITIT UNIVERSITY   (Turkey)

^b ANKARA UNIVERSITY   (Turkey)

^c Dr Sami Ulus Maternity and Children Training and Research Hospital   (Turkey)

^d AKDENIZ UNIVERSITY   (Turkey)

^e GULHANE SCHOOL OF MEDICINE   (Turkey)

^f KONYA TRAINING AND RESEARCH HOSPITAL   (Turkey)

^g ADNAN MENDERES UNIVERSITY   (Turkey)

^h ATATURK UNIVERSITY   (Turkey)

ⁱ Balikesir Ataturk Hospital   (Turkey)

^j CELAL BAYAR UNIVERSITY   (Turkey)

^k CUMHURIYET UNIVERSITY   (Turkey)

^l CUKUROVA UNIVERSITY   (Turkey)

^m DICLE UNIVERSITY   (Turkey)

ⁿ Ankara Children's Hematology Oncology Training and Research Hospital   (Turkey)

^o DOKUZ EYLUL UNIVERSITY   (Turkey)

^p EGE UNIVERSITY   (Turkey)

^q Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital   (Turkey)

^r GAZI UNIVERSITY   (Turkey)

^s GAZIANTEP UNIVERSITY   (Turkey)

^t Gaziantep Children's Hospital   (Turkey)

^u HACETTEPE UNIVERSITY   (Turkey)

^v INONU UNIVERSITY   (Turkey)

^w Tepecik Research and Training Hospital   (Turkey)

^x KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

^y Kanuni Sultan Suleyman Training and Research Hospital   (Turkey)

^z Kayseri Training and Research Hospital   (Turkey)

^aa Samsun Maternity and Child Health Hospital   (Turkey)

^ab Ssl Etfal Education and Research Hospital   (Turkey)

^ac GAZIOSMANPASA UNIVERSITY   (Turkey)

^ad TRAKYA UNIVERSITY   (Turkey)

^ae ULUDAG UNIVERSITY   (Turkey)

^af Emergency Department   (Turkey)

^ag YUZUNCU YIL UNIVERSITY   (Turkey)

^ah Zekai Tahir Burak Maternity Teaching Hospital   (Turkey)

more..

Author keywords

Neonatal intensive care unit; newborn; nosocomial; outbreak; respiratory syncytial virus

Indexed keywords

ACETYLCYSTEINE; ADRENALIN; CORTICOSTEROID; DORNASE ALFA; IPRATROPIUM BROMIDE; MACROLIDE; MONOCLONAL ANTIBODY; OXYGEN; PALIVIZUMAB; PYROXYLIN; SALBUTAMOL; SODIUM CHLORIDE; ANTIVIRUS AGENT;

ARTICLE; ARTIFICIAL VENTILATION; ATELECTASIS; BACTERIAL INFECTION; BODY WEIGHT; COMMUNITY ACQUIRED INFECTION; DIAGNOSTIC KIT; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HOSPITAL ADMISSION; HOSPITAL INFECTION; HOSPITAL PATIENT; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; INCIDENCE; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MULTICENTER STUDY; NEWBORN; NEWBORN INTENSIVE CARE; NEWBORN MORTALITY; NONINVASIVE VENTILATION; OXYGEN THERAPY; PREDICTIVE VALUE; PREMATURITY; PRIORITY JOURNAL; PROGNOSIS; PROPHYLAXIS; PROSPECTIVE STUDY; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SCREENING TEST; SEASONAL VARIATION; SENSITIVITY AND SPECIFICITY; TURKEY (REPUBLIC); CLINICAL TRIAL; CROSS INFECTION; EPIDEMIC; HOSPITALIZATION; INFANT; INFANT, NEWBORN, DISEASES; NEONATAL INTENSIVE CARE UNIT; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY TRACT INFECTIONS; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME; TURKEY;

ANTIVIRAL AGENTS; CROSS INFECTION; DISEASE OUTBREAKS; FEMALE; HOSPITALIZATION; HUMANS; INFANT; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; INTENSIVE CARE UNITS, NEONATAL; MALE; PALIVIZUMAB; PROGNOSIS; PROSPECTIVE STUDIES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RESPIRATORY TRACT INFECTIONS; TREATMENT OUTCOME; TURKEY;

EID: 84941242331     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2015.1079614     Document Type: Article

References (42)

1. Leader S, Kohlhase K. Recent trends in severe respiratory syncytial virus (RSV) among US infants, 1997 to 2000. J Pediatr 2003;143: 127-32.
2. Boyce TG, Mellen BG, Mitchel Jr EF, et al. Rates of hospitalization for respiratory syncytial virus infection among children in medicaid. J Pediatr 2000;137:865-70.
3. Welliver RC. Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection. J Pediatr 2003; 143:112-17.
4. Langley GF, Anderson LJ. Epidemiology and prevention of respiratory syncytial virus infections among infants and young children. Pediatr Infect Dis J 2011;30:510-5107.
5. Park HW, Lee BS, Kim AR, et al. Epidemiology of respiratory syncytial virus infection in infants born at less than thirty-five weeks of gestational age. Pediatr Infect Dis J 2012;31:99-104.
6. Turkish Neonatal Society. The seasonal variations of respiratory syncytial virus infections in Turkey: A 2-year epidemiological study. Turk J Pediatr 2012;54:216-22.
7. Bloemers BL, van Furth AM, Weijerman ME, et al. Down syndrome: A novel risk factor for respiratory syncytial virus bronchiolitis-A prospective birth-cohort study. Pediatrics 2007; 120:1076-81.
8. Weisman LE. Populations at risk for developing respiratory syncytial virus and risk factors for respiratory syncytial virus severity: infants with predisposing conditions. Pidj 2003;22: 33-7.
9. de Sierra TM, Kumar ML, Wasser TE, et al. Respiratory syncytial virus-specific immunoglobulins in preterm infants. J Pediatr 1993; 122:787-91.
10. Stein RT, Sherrill D, Morgan WJ, et al. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 1999;354:541-5.
11. Abadesso C, Almeida HI, Virella D, et al. Use of palivizumab to control an outbreak of syncytial respiratory virus in a neonatal intensive care unit. J Hosp Infect 2004;58:38-41.
12. Kurz H, Herbich K, Janata O, et al. Experience with the use of palivizumab together with infection control measures to prevent respiratory syncytial virus outbreaks in neonatal intensive care units. J Hosp Infect 2008;70:246-52.
13. Dizdar EA, Aydemir C, Erdeve O, et al. Respiratory syncytial virus outbreak defined by rapid screening in a neonatal intensive care unit. J Hosp Infect 2010;75:292-4.
14. Alan S, Okulu E, Kiliç A, et al. Palivizumab use during respiratory syncytial virus outbreak in the neonatal intensive care unit. J Hosp Infect 2012;81:292-3.
15. Alan S, Cakir U, Erdeve O, et al. Palivizumab prophylaxis during respiratory syncytial virus outbreak in the neonatal intensive care unit. Turk J Pediatr 2013;55:237-8.
16. Cox RA, Rao P, Brandon-Cox C. The use of palivizumab monoclonal antibody to control an outbreak of respiratory syncytial virus infection in a special care baby unit. J Hosp Infect 2001;48: 186-92.
17. Halasa NB, Williams JV, Wilson GJ, et al. Medical and economic impact of a respiratory syncytial virus outbreak in a neonatal intensive care unit. Pediatr Infect Dis J 2005;24:1040-4.
18. Silva Cde A, Dias L, Baltieri SR, et al. Respiratory syncytial virus outbreak in neonatal intensive care unit: impact of infection control measures plus palivizumab use. Antimicrob Resist Infect Control 2012;1:16.
19. Piedimonte G, Perez MK. Respiratory syncytial virus infection and bronchiolitis. Pediatr Rev 2014;35:519-30.
20. Nair H, Nokes DJ, Gessner BD, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: A systematic review and meta-analysis. Lancet 2010;375: 1545-55.
21. Houben ML, Bont L, Wilbrink B, et al. Clinical prediction rule for RSV bronchiolitis in healthy newborns: prognostic birth cohort study. Pediatrics 2011;127:35-41.
22. Cho HJ, Shim SY, Son DW, et al. Respiratory viruses in neonates hospitalized with acute lower respiratory tract infections. Pediatr Int 2013;55:49-53.
23. McConnochie KM, Hall CB, Walsh EE, Roghmann KJ. Variation in severity of respiratory syncytial virus infections with subtype. J Pediatr 1990;117:52-62.
24. Zhang XB, Liu LJ, Qian LL, et al. Clinical characteristics and risk factors of severe respiratory syncytial virus-associated acute lower respiratory tract infections in hospitalized infants. World J Pediatr 2014;10:360-4.
25. Arruda E, Jones MH, Escremim de Paula F, et al. The burden of single virus and viral coinfections on severe lower respiratory tract infections among preterm infants: A prospective birth cohort study in Brazil. Pediatr Infect Dis J 2014;33:997-1003.
26. Gonçalves A, Rocha G, Guimaraẽs H, et al. Value of chest radiographic pattern in RSV disease of the newborn: A multicenter retrospective cohort study. Crit Care Res Pract 2012;2012:861867.
27. Levin D, Tribuzio M, Green-Wrzesinki T, et al. Empiric antibiotics are justified for infants with respiratory syncytial virus lower respiratory tract infection presenting with respiratory failure: A prospective study and evidence review. Pediatr Crit Care Med 2010; 11:390-5.
28. Byington CL, Wilkes J, Korgenski K, Sheng X. Respiratory syncytial virus-associated mortality in hospitalized infants and young children. Pediatrics 2015;135:e24-31.
29. Thompson WW, Shay DK, Weintraub E, et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003;8289:179-86.
30. Figueras J, Carbonell X, Quero J, et al. IRIS Study Group. FLIP-2 Study: risk factors linked to respiratory syncytial virus infection requiring hospitalization in premature infants born in Spain at a gestational age of 32 to 35 weeks. Pediatr Infect Dis J 2008;27: 788-93.
31. Thorburn K, Eisenhut M, Riordan A. Mortality and morbidity of nosocomial respiratory syncytial virus (RSV) infection in ventilated children-A ten year perspective. Minerva Anestesiol 2012;78:782-9.
32. Lee YI, Peng CC, Chiu NC, et al. Risk factors associated with death in patients with severe respiratory syncytial virus infection. J Microbiol Immunol Infect 2014. [Epub ahead of print]. doi: 10.1016/j.jmii.2014.08.020.
33. Cilla G, Sarasua A, Montes M, et al. Risk factors for hospitalization due to respiratory syncytial virus infection among infants in the Basque Country, Spain. Epidemiol Infect 2006;134:506-13.
34. Lloyd PC, May L, Hoffman D, et al. The effect of birth month on the risk of respiratory syncytial virus hospitalization in the first year of life in the United States. Pediatr Infect Dis J 2014;33: 135-40.
35. Heerens AT, Marshall DD, Bose CL. Nosocomial respiratory syncytial virus: A threat in the modern neonatal intensive care unit. J Perinatol 2002;22:306-7.
36. Blanken MO, Rovers MM, Molenaar JM, et al. Dutch RSV Neonatal Network. Respiratory syncytial virus and recurrent wheeze in healthy preterm infants. N Engl J Med 2013;368:1791-9.
37. Hall CB. Nosocomial respiratory syncytial virus infections: The "Cold War" has not ended. Clin Infect Dis 2000;31:590-6.
38. Committee on Infectious Diseases from the American Academy of Pediatrics. Policy statements-Modified recommendations for use of palivizumab for prevention of respiratory syncytial virus infections. Pediatrics 2009;124:1694-701.
39. Oncel MY, Mutlu B, Kavurt S, et al. Respiratory syncytial virus prophylaxis in preterm infants: A cost-effectiveness study from Turkey. Turk J Pediatr 2012;54:344-51.
40. Oncel MY, Arayici S, Simsek GK, et al. Risk factors for hospitalization due to lower respiratory tract infection in preterm infants on palivizumab prophylaxis. Iran J Pediatr 2013;23:693-700.
41. Committee on Infectious Diseases and Bronchiolitis Guidelines Committee. Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection. Pediatrics 2014;134: 415-20.
42. Yen AB, Harrison G. Rapid antigen testing to detect respiratory syncytial virus performs well in neonates. Pediatr Infect Dis J 2011; 30:234-7.