On the Mechanism of Asymmetric Epoxidation with Titanium-Tartrate Catalysts

Asymmetric Synthesis

Volumn , Issue , 1985, Pages 247-308

  Finn, M G ^a   Sharpless, K Barry ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMISTRY; SPEECH SYNTHESIS;

ASYMMETRIC EPOXIDATION;

TITANIUM;

EID: 84941216140     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-08-092493-9.50013-X     Document Type: Chapter

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177. 2 is the matrix used):.
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180. Hanson, R. M., and Sharpless, K. B., submitted for publication.
181. d. Ko, S.-Y., Hollinshead, D. M., and Sharpless, K. B., unpublished results. When the allyl alcohol epoxidation reaction mixture is treated with the effective nucleophile thiophenol (PhSH) in the presence of added Ti(OiPr)4, the epoxy alcohol is opened in situ to give 3-thiophenoxy-1,2-propanediol in 88% yield and 89% ee.
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195. 3 in solution has two five-coordinate titanium centers in each trimer unit [.
196. 2:.
197. 2:.
198. 2:.
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202. 3:.