Long-term administration of dienogest reduces recurrence after excision of endometrioma

Journal of Endometriosis

Volumn 7, Issue 2, 2015, Pages 63-67

  Ota, Yoshiaki ^a   Andou, Masaaki ^a   Yanai, Shiori ^a   Nakajima, Saori ^a   Fukuda, Mika ^a   Takano, Mizuki ^a   Kurotsuchi, Shozo ^a   Ebisawa, Keiko ^a   Hada, Tomonori ^a   Ota, Ikuko ^b  

^a General Incorporated Foundation Kurashiki Medical Center   (Japan)

^b Kurashiki Heisei Hospital   (Japan)

Author keywords

Dienogest; Endometrioma; Endometriosis; Laparoscopy; Recurrence

Indexed keywords

BAZEDOXIFENE; DIENOGEST; ESTROGEN; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ESTRADIOL; HEMOGLOBIN;

ADULT; ARTICLE; BONE DENSITY; BREAST TENDERNESS; CONTROLLED STUDY; DEPRESSION; DUAL ENERGY X RAY ABSORPTIOMETRY; ENDOMETRIUM TUMOR; FEMALE; HOT FLUSH; HUMAN; LAPAROSCOPY; MAJOR CLINICAL STUDY; METRORRHAGIA; NUCLEAR MAGNETIC RESONANCE IMAGING; RETROSPECTIVE STUDY; TRANSVAGINAL ECHOGRAPHY; TUMOR RECURRENCE; VAGINA BLEEDING; ANEMIA; BLOOD CELL COUNT; BONE TURNOVER; CANCER RECURRENCE; CONSTIPATION; FOLLOW UP; RECURRENCE RISK; WEIGHT GAIN;

EID: 84941209031     PISSN: 20359969     EISSN: 2036282X     Source Type: Journal    
DOI: 10.5301/je.5000219     Document Type: Article

References (23)

1. Giudice LC, Kao LC. Endometriosis. Lancet. 2004;364(9447): 1789-1799.
2. Liu X, Yuan L, Shen F, Zhu Z, Jiang H, Guo SW. Patterns of and risk factors for recurrence in women with ovarian endometriomas. Obstet Gynecol. 2007;109(6):1411-1420.
3. Kitajima M, Dolmans MM, Donnez O, Masuzaki H, Soares M, Donnez J. Enhanced follicular recruitment and atresia in cortex derived from ovaries with endometriomas. Fertil Steril. 2014;101(4):1031-1037.
4. Busacca M, Marana R, Caruana P, et al. Recurrence of ovarian endometrioma after laparoscopic excision. Am J Obstet Gynecol. 1999;180(3 Pt 1):519-523.
5. Saleh A, Tulandi T. Reoperation after laparoscopic treatment of ovarian endometriomas by excision and by fenestration. Fertil Steril. 1999;72(2):322-324.
6. Ghezzi F, Beretta P, Franchi M, Parissis M, Bolis P. Recurrence of ovarian endometriosis and anatomical location of the primary lesion. Fertil Steril. 2001;75(1):136-140.
7. Jones KD, Sutton CJ. Recurrence of chocolate cysts after laparoscopic ablation. J Am Assoc Gynecol Laparosc. 2002;9(3): 315-320.
8. Vercellini P, Chapron C, De Giorgi O, Consonni D, Frontino G, Crosignani PG. Coagulation or excision of ovarian endometriomas? Am J Obstet Gynecol. 2003;188(3):606-610.
9. Koga K, Takemura Y, Osuga Y, et al. Recurrence of ovarian endometrioma after laparoscopic excision. Hum Reprod. 2006;21(8):2171-2174.
10. Köhler G, Faustmann TA, Gerlinger C, Seitz C, Mueck AO. A dose-ranging study to determine the efficacy and safety of 1, 2, and 4 mg of dienogest daily for endometriosis. Int J Gynaecol Obstet. 2010;108(1):21-25.
11. Vercellini P, DE Matteis S, Somigliana E, Buggio L, Frattaruolo MP, Fedele L. Long-term adjuvant therapy for the prevention of postoperative endometrioma recurrence: a systematic review and meta-analysis. Acta Obstet Gynecol Scand. 2013;92(1):8-16.
12. Vercellini P, Eskenazi B, Consonni D, et al. Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis. Hum Reprod Update. 2011;17(2):159-170.
13. Halleen JM, Alatalo SL, Janckila AJ, Woitge HW, Seibel MJ, Väänänen HK. Serum tartrate-resistant acid phosphatase 5b is a specific and sensitive marker of bone resorption. Clin Chem. 2001;47(3):597-600.
14. Harada T, Taniguchi F. Dienogest: a new therapeutic agent for the treatment of endometriosis. Womens Health (Lond Engl). 2010;6(1):27-35.
15. Sasagawa S, Shimizu Y, Kami H, et al. Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile. Steroids. 2008;73(2):222-231.
16. Coccia ME, Rizzello F, Mariani G, Bulletti C, Palagiano A, Scarselli G. Ovarian surgery for bilateral endometriomas influences age at menopause. Hum Reprod. 2011;26(11):3000-3007.
17. Harada T, Momoeda M, Taketani Y, et al. Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis: a randomized, double-blind, multicenter, controlled trial. Fertil Steril. 2009;91(3):675-681.
18. Sasagawa S, Shimizu Y, Nagaoka T, Tokado H, Imada K, Mizuguchi K. Dienogest, a selective progestin, reduces plasma estradiol level through induction of apoptosis of granulosa cells in the ovarian dominant follicle without follicle-stimulating hormone suppression in monkeys. J Endocrinol Invest. 2008;31(7):636-641.
19. Klipping C, Duijkers I, Faustmann T, Klein SF, Schuett B. Pharmacodynamic study of four oral dosages of dienogest. Fertil Steril. 2010;94(4)(Suppl 1):S181.
20. Barbieri RL. Hormone treatment of endometriosis: the estrogen threshold hypothesis. Am J Obstet Gynecol. 1992;166(2): 740-745.
21. Momoeda M, Taketani Y. [Randomized double-blind, multicenter, parallel-group dose–response study of dienogest in patients with endometriosis] [article in Japanese]. Jpn Pharmacol Ther. 2007;35:769-783.
22. Kitawaki J, Kusuki I, Yamanaka K, Suganuma I. Maintenance therapy with dienogest following gonadotropin-releasing hormone agonist treatment for endometriosis-associated pelvic pain. Eur J Obstet Gynecol Reprod Biol. 2011;157(2): 212-216.
23. Granese R, Perino A, Calagna G, et al. Gonadotrophin-releasing hormone analogue or dienogest plus estradiol valerate to prevent pain recurrence after laparoscopic surgery for endometriosis: a multi-center randomized trial. Acta Obstet Gynecol Scand. 2015;94(6):637-645.