Tip variant of focal segmental glomerulosclerosis: Is it truly a benign variant?

Renal Failure

Volumn 37, Issue 5, 2015, Pages 763-768

  Trivedi, Mayuri ^a,c   Pasari, Amit ^a   Chowdhury, Arpita Roy ^a   Abraham, Anila ^b   Pandey, Rajendra ^a  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^b MADRAS MEDICAL MISSION HOSPITAL   (India)

^c Department of Nephrology ^*  (India)

Author keywords

Focal segmental glomerulosclerosis; India; nephrotic syndrome; NOS variant; tip variant

Indexed keywords

CREATININE; MYCOPHENOLATE MOFETIL; STEROID; TACROLIMUS;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; FIBROSING ALVEOLITIS; FOCAL GLOMERULOSCLEROSIS; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYALINE DEGENERATION; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY BIOPSY; MALE; PRIORITY JOURNAL; PROTEINURIA; REMISSION; RETROSPECTIVE STUDY; SCLEROSIS; STEROID THERAPY; TREATMENT OUTCOME; ADOLESCENT; BIOPSY; INDIA; MIDDLE AGED; PATHOLOGY; PROGNOSIS; YOUNG ADULT;

ADOLESCENT; ADULT; BIOPSY; CREATININE; FEMALE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; IMMUNOSUPPRESSION; INDIA; MALE; MIDDLE AGED; PROGNOSIS; PROTEINURIA; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84941136134     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2015.1014755     Document Type: Article

References (24)

1. DAgati V. Pathologic classification of focal segmental glomerulosclerosis. Semin Nephrol. 2003; 23: 117-134.
2. DAgati V. The many masks of focal segmental glomerulosclerosis. Kidney Int. 1994; 46: 1223-1241.
3. Cameron JS. The enigma of focal segmental glomerulosclerosis. Kidney Int. 1996; 50 (Suppl. 57): S119-S131.
4. Haas M, Spargo BH, Coventry S. Increasing incidence of focal segmental glomerulosclerosis amongst adult nephropathies: A 20 years renal biopsy study. Am J Kidney Dis. 1995; 26: 740-750.
5. Abrantes MM, Cardoso LS, Lima EM, et al. Predictive factors for chronic kidney disease in primary focal segmental glomerulosclerosis. Pediatr Nephrol. 2006; 21: 1003-1032.
6. Chitalia VC, Wells JE, Robson RA, Searle M, Lynn KL. Predicting renal survival in primary focal segmental glomerulosclerosis from the time of presentation. Kidney Int. 1999; 56: 2236-2242.
7. DAgati VD, Fogo AB, Bruijn JA. Pathologic classification of focal segmental glomerulosclerosis: A working proposal. Am J Kidney Dis. 2004; 43: 368-382.
8. Thomas DB, Franceschini N, Hogan SL, et al. Clinical and pathologic characteristics of focal segmental glomerulosclerosis pathologic variants. Kidney Int. 2006; 69: 92-926.
9. Schwartz MM, Korbet SM, Rydell J, Borok R, Genchi R. Primary focal segmental glomerulosclerosis in adults: Prognostic value of histologic variants. Am J Kidney Dis. 1995; 25: 845-852.
10. Abrantes MM, Cardoso LS, Lima EM, et al. Clinical course of 110 children and adolescents with primary focal segmental glomerulosclerosis. Pediatr Nephrol. 2006; 21: 482-489.
11. Howie AJ, Pankhurst T, Sarioglu S, Turhan N, Adu D. Evolution of nephritic-associated focal segmental glomerulosclerosis: A clinicopathologic study. Kidney Int. 2005; 50: 1734-1746.
12. Howie AJ, Brewer DB. The glomerular tip lesion: A previously undescribed type of segmental glomerular abnormality. J Pathol. 1984; 142: 205-220.
13. Howie AJ, Lee SJ, Green NJ, et al. Different clinicopathological types of segmental sclerosing glomerular lesions in adults. Nephrol Dial Transplant. 1993; 8: 590-599.
14. Ito H, Yoshikawa N, Aozai F, et al. Twenty-seven children with focal segmental glomerulosclerosis: Correlation between the segmental location of the glomerular lesions and prognosis. Clin Nephrol. 1984; 22: 9-14.
15. Howie AJ, Brewer DB. Further studies on the glomerular tip lesion: Early and late stages and life table analysis. J Pathol. 1985; 147: 245-255.
16. Chun MJ, Korbet SM, Schwartz MM, et al. Focal segmental glomerulosclerosis in nephrotic adults: Presentation, prognosis, and response to therapy of the histologic variants. J Am Soc Nephrol. 2004; 15: 2169-2177.
17. KDIGO Clinical practice guidelines for glomerulonephritis. Kidney Int Suppl. 2012; 2: 139.
18. Dagati VD, Alster JM, Charles Jennette J, et al. Association of histological variants in FSGS clinical trial with presenting features and outcomes. Clin J Am Soc Nephrol. 2013; 8: 399-406.
19. Haas M, Yousefzadeh N. Glomerular tip lesion in minimal change nephropathy: A study of autopsies before 1950. Am J Kidney Dis. 2002; 39: 1168-1175.
20. Paik KH, Lee BH, Cho HY, et al. Primary focal segmental glomerular sclerosis in children: Clinical course and prognosis. Pediatr Nephrol. 2007; 22: 389-395.
21. Morita M, White RH, Coad NA, et al. The clinical significance of the glomerular location of segmental lesions in focal segmental glomerulosclerosis. Clin Nephrol. 1990; 33: 211-219.
22. Huppes W, Hene RJ, Kooiker CJ. The glomerular tip lesion: A distinct entity or not? J Pathol. 1988; 154: 187-190.
23. Arias LF, Franco-Alzate C, Rojas SL. Tip variant of focal glomerulosclerosis: Outcome and comparison to not otherwise specified variant. Nephrol Dial Transplant. 2011; 26: 2215-2221.
24. Stokes MB, Markowitz GS, Lin J, et al. Glomerular tip lesion: a distinct entity within the minimal change disease/focal segmental glomerulosclerosis spectrum. Kidney Int. 2004; 65: 1690-1702