Omega-3 fatty acids: A novel resort against gastrointestinal injury

European Review for Medical and Pharmacological Sciences

Volumn 18, Issue 20, 2014, Pages 3086-3090

  Ianiro, G ^a   Franceschi, F ^a   Bibbo S ^a   Gasbarrini, A ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Cyclooxygenases; Gastric barrier; Gastrointestinal injury; Omega 3 fatty acids; Prostaglandins

Indexed keywords

FISH OIL; ICOSAPENTAENOIC ACID; OMEGA 3 FATTY ACID; PROSTAGLANDIN; ANTIINFLAMMATORY AGENT;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER PREVENTION; DIGESTIVE SYSTEM INJURY; GASTRIC MUCOSA; HELICOBACTER INFECTION; HUMAN; NONHUMAN; PROSTAGLANDIN SYNTHESIS; STOMACH EPITHELIUM; STOMACH INJURY; STOMACH PROTECTION; ANIMAL; CASE CONTROL STUDY; GASTROINTESTINAL DISEASES; METABOLISM; PATHOLOGY; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; THROMBOSIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CASE-CONTROL STUDIES; EICOSAPENTAENOIC ACID; FATTY ACIDS, OMEGA-3; GASTROINTESTINAL DISEASES; HUMANS; PROSPECTIVE STUDIES; PROSTAGLANDINS; RETROSPECTIVE STUDIES; THROMBOSIS;

EID: 84941118606     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. DEFILIPPIS AP, SPERLING LS. Understanding omega-3's. Am Heart J 2006; 151: 564-570.
2. SIMOPOULOS AP. Essential fatty acids in health and chronic disease. Am J Clin Nutr 1999; 70(3 Suppl): 560S-569S.
3. EATON SB, KONNER M. Paleolithic nutrition. A consideration of its nature and current implications. N Engl J Med 1985; 312: 283-289.
4. PERK J, DE BACKER G, GOHLKE H, GRAHAM I, REINER Z, VERSCHUREN M, ALBUS C, BENLIAN P, BOYSEN G, CIFKOVA R, DEATON C, EBRAHIM S, FISHER M, GERMANO G, HOBBS R, HOES A, KARADENIZ S, MEZZANI A, PRESCOTT E, RYDEN L, SCHERER M, SYVÄNNE M, SCHOLTE OP REIMER WJ, VRINTS C, WOOD D, ZAMORANO J L, ZANNAD F; European Association for Cardiovascular Prevention & Rehabilitation (EACPR); ESC Committee for Practice Guidelines (CPG). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J 2012; 33: 1635-1701.
5. JOINT WORLD HEALTH ORGANIZATION/FOOD AND AGRICULTURE ORGANI ZATION EXPERT CONSULTATION. Diet, Nutrition and the Prevention of Chronic Disease. Accessed at http://whqlibdoc.who.int/trs/WHO-TRS-916.pdf on 18 July 2013.
6. TAKEZAKI T, INOUE M, KATAOKA H, IKEDA S, Y OSHIDA M, OHASHI Y, TAJIMA K, TOMINAGA S. Diet and lung cancer risk from a 14-year population-based prospective study in Japan: with special reference to fish consumption. Nutr Cancer 2003; 45: 160-167.
7. KATO I, AKHMEDKHANOV A, KOENIG K, TONIOLO PG, SHORE RE, RIBOLI E. Prospective study of diet and female colorectal cancer: the New York University Women's Health Study.Nutr Cancer 1997; 28: 276-281.
8. CHOWDHURY R, WARNAKULA S, KUNUTSOR S, CROWE F, WARD HA, JOHNSON L, FRANCO OH, BUTTERWORTH AS, FOROUHI NG, THOMPSON SG, KHAW KT, MOZAFFARIAN D, DANESH J, DI ANGELANTONIO E. Association of dietary, circulating, and su pplement fatty acids with coronary risk: a systematic review and meta-Analysis. Ann Intern Med 2014; 160: 398-406.
9. MACLEAN CH, NEWBERRY SJ, MOJICA WA, KHANNA P, ISSA AM, SUTTORP MJ, LIM YW, TRAINA SB, HILTON L, GARLAND R, MORTON SC. Effects of omega-3 fatty acids on cancer risk: a systematic review. JAMA 2006; 295: 403-415.
10. GASBARRINI A,D'AVERSA F,DI RIENZO T,FRANCESCHI F. Nutrients affecting gastric barrier Dig Dis 2014 32 243-248.
11. CHAN FK. COX-2 inhibition, H. pylori infection and the risk of gastrointestinal complications. Curr Pharm Des 2003; 9: 2213-2219.
12. DUBOIS RN, ABRAMSON SB, CROFFORD L, GUPTA RA, SIMON LS, VAN DE PUTTE LB, LIPSKY PE. Cyclooxygenase in biology and disease. FASEB J 1998; 12: 1063-1073.
13. HAWKEY CJ. Nonsteroidal anti-inflammatory drug gastropathy.Gastroenterology 2000; 119: 521-535.
14. LAINE L, HARPER S, SIMON T, BATH R, JOHANSON J, SCHWARTZ H, STER N S, QUAN H, BOLOGNESE J. A randomized trial comparing the effect of rofecoxib, a cyclooxygenase 2-specific inhibitor, with that of ibuprofen on the gastroduodenal mucosa of patients with osteoarthritis. Rofecoxib Osteoarthritis Endoscop y Study Group. Gastroenterology 1999; 117: 776-783.
15. CLELAND LG. Clinical and biochemical effects of dietary fish oil supplements in rheumatoid arthritis. J Rheumatol 1988; 15: 1471-1475.
16. MAROON JC, BOST JW. Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain. Surg Neurol 2006; 65: 326-331.
17. DAS UN. Interaction(s) between essential fatty acids, eicosanoids, cytokines, growth factors and free radicals-relevance to new therapeutic strategies in rheumatoid arthritis and other collagen vascular diseases. Prostaglandins Leukot E ssent Fatty Acids 1991; 44: 201-210.
18. CULP BR, BRADLEY TG, LANDS WE. Inhibition of prostaglandin biosynthesis by eicosapentaenoic acid. Prostaglandins Med 1979; 3: 269-278.
19. FISCHER S, VON SCHACKY C, SCHWEER H. Prostaglandins E3 and F3 alpha are excreted in human urine after ingestion of n-3 polyunsaturated fatty acids. Biochim Biophys Acta 1988; 963: 501-508.
20. KNAPP HR. Prostaglandins in human semen during fish oil ingestion: evidence for in vivo cyclooxygenase inhibition and appearance of novel tr ienoic compounds. Prostaglandins 1990; 39: 407-423.
21. BAG GA D, WANG L, FARIAS-EISNER R, GLASPY JA, REDDY ST. Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc Natl Acad Sci U S A 2003; 100: 1751-1756.
22. SETHI S. Inhibition of leukocyte-endothelial interactions by oxidized omega-3 fatty acids: a novel mechani sm for the anti-inflammatory effects of omega-3 fatty acids in fish oil. Redox Rep 2002; 7: 369-378.
23. HUNTER B, MCDONALD GS, GIBNEY MJ. The effects of acute and chronic administration of n-6 and n-3 polyunsaturated fatty acids on ethanol-induced gastric haemorrhage in rats. Br J Nutr 1992; 67: 501-507.
24. LEUNG FW. Prostaglandins mediate fish oil protection against ethanol-induced gastric mucosal injury in rats. Dig Dis Sci 1994; 39: 893.
25. AL-HARBI MM, ISLAM MW, AL-SHABANAH OA, ALGHARABLY NM. Effect of acute administration of fish oil (omega-3 marine triglyceride) on gastric ulceration a nd secretion induced by various ulcerogenic and necrotizing agents in rats. Food Chem Toxicol 1995; 33: 553-558.
26. BHATTACHARYA A, GHOSAL S, BHATTACHARYA SK. Effect of fish oil on offensive and def ensive factors in gastric ulceration in rats. Prostaglandins Leukot Essent Fatty Acids 2006; 74: 109-116.
27. PINEDA-PEÑ A EA, JIMÉNEZ-ANDRADE JM, CASTAÑEDA-HERNÁNDEZ G, CHÁVEZ-PIÑA AE. Docosahexa enoic acid, an omega-3 polyunsaturated acid protects against indomethacin-induced gastric injury. Eur J Pharmacol 2012; 697: 139-143.
28. YU JH, KANG SG, JUNG UY, JUN CH, KIM H. Effects of o mega-3 fatty acids on apoptosis of human gastric epithelial cells exposed to silica-immobilized glucose oxidase. Ann N Y Acad Sci 2009; 1171: 359-364
29. LUGEA A, SALAS A, GUARNER F, MALAGELADA JR. Influence of dietary fat on duodenal resistance to acid. Gut 1993; 34: 1303-1309.
30. HOLLANDER D, TARNAWSKI A. Dietary essential fatty acids and decline in peptic ulcer disease-A hypothesis. Gut 1986; 27: 239-242.
31. THOMPSON L,COCKAYNE A,SPILLER RC. Inhibitory effect of polyunsaturated fatty acids on the growth of Helicobacter pylori: a possible explanation of the effect of diet on peptic ulceration Gut 1994 35 1557-1561.
32. CORREIA M, MICHEL V, M ATOS AA, CARVALHO P, OLIVEIRA MJ, FERREIRA RM, DILLIES MA, HUERRE M, SERUCA R, FIGUEIREDO C, MACHADO JC, TOUATI E. Docosahexaenoic acid inhibits Helicobacter pylori growth in vitro and mice gastric mucosa colonizat ion. PLoS One 2012; 7: e35072.