Marked Regional Variation in Acute Stroke Treatment among Medicare Beneficiaries

Stroke

Volumn 46, Issue 7, 2015, Pages 1890-1896

  Skolarus, Lesli E ^a   Meurer, William J ^a,b   Shanmugasundaram, Krithika ^c   Adelman, Eric E ^a   Scott, Phillip A ^a,b   Burke, James F ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Department of Emergency Medicine ^*  (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

health services research; stroke; therapeutic thrombolysis

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

AGED; ARTICLE; BRAIN ISCHEMIA; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEMOGRAPHY; EMERGENCY HEALTH SERVICE; EMERGENCY WARD; FEMALE; FIBRINOLYTIC THERAPY; GEOGRAPHIC DISTRIBUTION; HEALTH CARE DISPARITY; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL FEE; MEDICARE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; INSURANCE; STROKE; TREATMENT OUTCOME; TRENDS; UNITED STATES; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CROSS-SECTIONAL STUDIES; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; INSURANCE BENEFITS; MALE; MEDICARE; RETROSPECTIVE STUDIES; STROKE; THROMBOLYTIC THERAPY; TREATMENT OUTCOME; UNITED STATES;

EID: 84941096867     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.115.009163     Document Type: Article

References (24)

1. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-1587.
2. Berkhemer OA, Fransen PS, Beumer D, van den Berg LA, Lingsma HF, Yoo AJ, et al; MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015;372:11-20. doi: 10.1056/NEJMoa1411587.
3. Kleindorfer D, Xu Y, Moomaw CJ, Khatri P, Adeoye O, Hornung R. US geographic distribution of rt-PA utilization by hospital for acute ischemic stroke. Stroke. 2009;40:3580-3584. doi: 10.1161/STROKEAHA.109.554626.
4. Wennberg JE, ed. Appendix on the geography of health care in the United States. http://www.dartmouthatlas.org/downloads/methods/geogappdx. pdf. Accessed January 22, 2015.
5. Wennberg JE, ed. The dartmouth atlas of health care: Data by region. http://www.dartmouthatlas.org/data/region/. Accessed June 12, 2014.
6. Adams HP Jr, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, et al; American Heart Association; American Stroke Association Stroke Council; Clinical Cardiology Council; Cardiovascular Radiology and Intervention Council; Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke. 2007;38:1655-1711. doi: 10.1161/STROKEAHA.107.181486.
7. The Joint Commision. http://www.qualitycheck.org/consumer/searchQCR.aspx. Accessed October 16, 2014.
8. Song S, Saver J. Growth of regional acute stroke systems of care in the United States in the first decade of the 21st century. Stroke. 2012;43:1975-1978. doi: 10.1161/STROKEAHA.112.657809.
9. Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Blaha MJ, et al; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics-2014 update: a report from the American Heart Association. Circulation. 2014;129:e28-e292. doi: 10.1161/01.cir.0000441139.02102.80.
10. Wardlaw JM, Murray V, Berge E, del Zoppo G, Sandercock P, Lindley RL, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet. 2012;379:2364-2372. doi: 10.1016/S0140-6736(12)60738-7.
11. Kleindorfer D, Kissela B, Schneider A, Woo D, Khoury J, Miller R, et al; Neuroscience Institute. Eligibility for recombinant tissue plasminogen activator in acute ischemic stroke: a population-based study. Stroke. 2004;35:e27-e29. doi: 10.1161/01.STR.0000109767.11426.17.
12. Tong D, Reeves MJ, Hernandez AF, Zhao X, Olson DM, Fonarow GC, et al. Times from symptom onset to hospital arrival in the Get with the Guidelines-Stroke Program 2002 to 2009: temporal trends and implications. Stroke. 2012;43:1912-1917. doi: 10.1161/STROKEAHA.111.644963.
13. Marsh DR, Schroeder DG, Dearden KA, Sternin J, Sternin M. The power of positive deviance. BMJ. 2004;329:1177-1179. doi: 10.1136/bmj.329.7475.1177.
14. Lahr MM, Luijckx GJ, Vroomen PC, van der Zee DJ, Buskens E. Proportion of patients treated with thrombolysis in a centralized versus a decentralized acute stroke care setting. Stroke. 2012;43:1336-1340. doi:10.1161/STROKEAHA.111.641795.
15. Prabhakaran S, O'Neill K, Stein-Spencer L, Walter J, Alberts MJ. Prehospital triage to primary stroke centers and rate of stroke thrombolysis. JAMA Neurol. 2013;70:1126-1132. doi: 10.1001/jamaneurol.2013.293.
16. Prabhakaran S, McNulty M, O'Neill K, Ouyang B. Intravenous thrombolysis for stroke increases over time at primary stroke centers. Stroke. 2012;43:875-877. doi: 10.1161/STROKEAHA.111.640060.
17. Lichtman JH, Allen NB, Wang Y, Watanabe E, Jones SB, Goldstein LB. Stroke patient outcomes in US hospitals before the start of the Joint Commission Primary Stroke Center certification program. Stroke. 2009;40:3574-3579. doi: 10.1161/STROKEAHA.109.561472.
18. Reeves M, Bhatt A, Jajou P, Brown M, Lisabeth L. Sex differences in the use of intravenous rt-PA thrombolysis treatment for acute ischemic stroke: a meta-analysis. Stroke. 2009;40:1743-1749. doi: 10.1161/STROKEAHA.108.543181.
19. Schwamm LH, Reeves MJ, Pan W, Smith EE, Frankel MR, Olson D, et al. Race/ethnicity, quality of care, and outcomes in ischemic stroke. Circulation. 2010;121:1492-1501. doi: 10.1161/CIRCULATIONAHA.109.881490.
20. Kleindorfer D, Lindsell CJ, Brass L, Koroshetz W, Broderick JP. National US estimates of recombinant tissue plasminogen activator use: ICD-9 codes substantially underestimate. Stroke. 2008;39:924-928. doi:10.1161/STROKEAHA.107.490375.
21. Adeoye O, Hornung R, Khatri P, Kleindorfer D. Recombinant tissuetype plasminogen activator use for ischemic stroke in the United States: a doubling of treatment rates over the course of 5 years. Stroke. 2011;42:1952-1955. doi: 10.1161/STROKEAHA.110.612358.
22. Qureshi AI, Harris-Lane P, Siddiqi F, Kirmani JF. International classification of diseases and current procedural terminology codes underestimated thrombolytic use for ischemic stroke. J Clin Epidemiol. 2006;59:856-858. doi: 10.1016/j.jclinepi.2006.01.004.
23. Lin GA, Dudley RA, Lucas FL, Malenka DJ, Vittinghoff E, Redberg RF. Frequency of stress testing to document ischemia prior to elective percutaneous coronary intervention. JAMA. 2008;300:1765-1773. doi:10.1001/jama.300.15.1765.
24. Fisher ES, Wennberg DE, Stukel TA, Gottlieb DJ, Lucas FL, Pinder EL. The implications of regional variations in Medicare spending. Part 1: the content, quality, and accessibility of care. Ann Intern Med. 2003;138:273-287.