Polypharmacy among adults aged 65 years and older in the United States: 1988â€"2010

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 70, Issue 8, 2015, Pages 989-995

  Charlesworth, Christina J ^a   Smit, Ellen ^a   Lee, David S H ^b   Alramadhan, Fatimah ^a   Odden, Michelle C ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Cardiovascular; Depression; Functional performance; Medication; Public health

Indexed keywords

AGED; EPIDEMIOLOGY; FEMALE; HUMAN; MALE; POLYPHARMACY; TIME FACTOR; UNITED STATES; VERY ELDERLY;

AGED; AGED, 80 AND OVER; FEMALE; HUMANS; MALE; POLYPHARMACY; TIME FACTORS; UNITED STATES;

EID: 84941026267     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glv013     Document Type: Review

References (28)

1. Hajjar E, Cafiero A, Hanlon J. Polypharmacy in elderly patients. Am J Geriatr Pharmacother. 2007;5:345-351. doi:10.1016/j.amjopharm. 2007.12.002
2. Gurwitz JH. Polypharmacy: a new paradigm for quality drug therapy in the elderly? Arch Intern Med. 2004;164:1957-1959. doi:10.1001/archinte.164.18.1957
3. Goulding MR. Inappropriate medication prescribing for elderly ambulatory care patients. Arch Intern Med. 2004;164:305-312. doi:10.1001/archinte.164.3.305
4. Zhan C, Sangl J, Bierman AS, et al. Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expen diture Panel Survey. JAMA. 2001;286:2823-2829. doi:10.1001/jama.286.22.2823
5. Koyama A, Steinman M, Ensrud K, Hillier TA, Yaffe K. Long-term cognitive and functional effects of potenti ally inappropriate medications in older women. J Gerontol A Biol Sci Med Sci. 2014;69:423-429. doi:10.1093/gerona/glt192
6. Maher RL, Hanlon J, Hajjar ER. Clinical consequences of polypharmacy in elderly. Expert Opin Drug Saf. 2014;13:57-65. doi:10.1517/14740338.2013.827660
7. Hilmer S, Gnjidic D. The effects of polypharmacy in older adults. Clin Pharmacol Ther. 2009;85:86-88. doi:10.1038/clpt.2008.224
8. Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med. 2003;163:2716-2724. doi:10.1001/archinte.163.22.2716
9. Gu Q, Dillon CF, Burt VL. Prescription Drug Use Continues to Increase: US Prescription Drug Data for 2007-2008. Hyattsville, MD: National Center for Health Statistics; 2010.
10. JyrkkäJ, Enlund H, Lavikainen P, Sulkava R, Hartikainen S. Association of polypharmacy with nut ritional status, functional ability and cognitive capacity over a three-year period in an elderly population. Pharmacoepidemiol Drug Saf. 2011;20:514-522. doi:10.1002/pds.2116
11. Kaufman DW, Kelly JP, Rosenberg L, Anderson TE, Mitchell AA. Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. JAMA. 2002;287:337-344. doi:10.1001/jama.287.3.337
12. CDC Patterns of Prescription Drug Use in the United States 1988-94. National Center for Health Statistics
13. Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P, Lindau ST. Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. JAMA. 2008;300:2867-2878. doi:10.1001/jama.2008.892
14. NHANES. 2009-10 Data Documentation, Codebook, and Frequencies: Prescription Medications (RXQ-RX-F), 2012. http://wwwn.cdc.gov/nchs/nhanes/2009-2010/RXQ-RX-F.htm. Accessed January 2015.
15. Johnson CL, Paulose-Ram R, Ogden CL. NHANES: Analytic Guidelines, 1999-2010. Vital & Health Statistics. 2013;2:6.
16. Osborn R, Moulds D, Squires D, Doty M, Anderson C. International survey of older adults finds shortcomings in access, coordination, and patient-centered care. Health Aff. 2014;33:2247-2255. doi:10.1377/hlthaff.2014.0947
17. Lim D, Jung K, Shi Y. National trends in the use of antidepressants between 1997 and 2009 and the role of Medicare Part D implementation. Psychiatr Serv. 2013;64:1038-1042. doi:10.1176/appi.ps.201200438
18. Donohue JM, Cevasco M, Rosenth al MB. A decade of direct-to-consumer advertising of prescription drugs. N Engl J Med. 2007;357:673-681. doi:10.1056/NEJMsa070502
19. Bromfield SG, Bowling CB, Tanner RM, et al. Trends in hypertension prevalence, awareness, treatment, and control among US adults 80 years and older, 1988-2010. J Clin Hypertens (Greenwich). 2014;16:270-276. doi:10.1111/jch.12281
20. Egan BM, Zhao Y, Axon RN. US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008. JAMA. 2010;303:2043-2050. doi:10.1001/jama.2010.650
21. Stone NJ, Robinson J, Lichtenstein AH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. November 12, 2013. doi:10.1161/01.cir.0000437738.63853.7a
22. AMDA. Choosing Wisely: Five Things Physicians and Patients Should Question.
23. Mojtabai R. Americans' attitudes toward mental health treatment seeking: 1990-2003. Psychiatr Serv. 2007;58:642-651. doi:10.1176/appi. ps.58.5.642
24. Anderson IM. Se lective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-Analysis of efficacy and tolerability. J Affect Disord. 2000;58:19-36. doi:10.1016/s0165-0327(99)00092-0
25. Peretti S, Judge R, Hindmarch I. Safety and tolerability considerations: tricyclic antidepressants vs. selective serotonin reuptake inhibitors. Acta Psychiatr Scand Suppl. 2000;403:17-25. doi:10.11 11/j.1600-0447.2000.tb10944.x
26. Chouinard G. The search for new off-label indications for antidepressant, antianxiety, antipsychotic and anticonvulsant drugs. J Psychiatry Neurosci. 2006;31:168-176.
27. Luppa M, Sikorski C, Luck T, et al. Age-And gender-specific prevalence of depression in latest-life-systematic review and meta-Analysis. J Affect Disord. 2012;136:212-221. doi:10.1016/j.jad.2 010.11.033
28. Peron EP, Gray SL, Hanlon JT. Medication use and functional status decline in older adults: a narrative review. Am J Geriatr Pharmacother. 2011;9:378-391. doi:10.1016/j.amjopharm .2011.10.002