Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility

eLife

Volumn 3, Issue , 2014, Pages

  Caesar, Joseph J E ^a   Lavender, Hayley ^a   Ward, Philip N ^a   Exley, Rachel M ^a   Eaton, Jack ^a   Chittock, Emily ^a   Malik, Talat H ^a   Goiecoechea De Jorge, Elena ^a   Pickering, Matthew C ^a   Tang, Christoph M ^a   Lea, Susan M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

complement evasion; genetic susceptibility; immunology; infectious disease; microbiology; Neisseria meningitidis

Indexed keywords

BACTERIAL PROTEIN; CFHR3 PROTEIN, HUMAN; COMPLEMENT FACTOR H; PLASMA PROTEIN;

AMINO ACID SEQUENCE; BACTERIAL MENINGITIS; CHEMISTRY; GENETIC PREDISPOSITION; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; NEISSERIA MENINGITIDIS; PATHOGENICITY; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BLOOD PROTEINS; COMPLEMENT FACTOR H; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HUMANS; MENINGITIS, BACTERIAL; MOLECULAR SEQUENCE DATA; NEISSERIA MENINGITIDIS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84940955773     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.04008     Document Type: Article

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