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Volumn 35, Issue 35, 2015, Pages 12303-12308

Non-ionotropic NMDA receptor signaling drives activity-induced dendritic spine shrinkage

Author keywords

Dendritic spine; Glutamate uncaging; Long term depression; NMDA receptor; Structural plasticity; Two photon microscopy

Indexed keywords

DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; 2,3-DIOXO-6-NITRO-7-SULFAMOYLBENZO(F)QUINOXALINE; AMINO ACID RECEPTOR BLOCKING AGENT; CALCIUM; CALMODULIN; GREEN FLUORESCENT PROTEIN; MAGNESIUM; MYOSIN LIGHT CHAIN KINASE; QUINOXALINE DERIVATIVE;

EID: 84940903437     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4289-14.2015     Document Type: Article
Times cited : (117)

References (42)
  • 1
    • 69749094446 scopus 로고    scopus 로고
    • NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses
    • CrossRef Medline
    • Akashi K, Kakizaki T, Kamiya H, Fukaya M, Yamasaki M, Abe M, Natsume R, Watanabe M, Sakimura K (2009) NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses. J Neurosci 29:10869-10882.CrossRef Medline
    • (2009) J Neurosci , vol.29 , pp. 10869-10882
    • Akashi, K.1    Kakizaki, T.2    Kamiya, H.3    Fukaya, M.4    Yamasaki, M.5    Abe, M.6    Natsume, R.7    Watanabe, M.8    Sakimura, K.9
  • 2
    • 34447502225 scopus 로고    scopus 로고
    • Distinct structural and ionotropic roles ofNMDAreceptors in controlling spine and synapse stability
    • CrossRef Medline
    • Alvarez VA, Ridenour DA, Sabatini BL (2007) Distinct structural and iono tropic roles ofNMDAreceptors in controlling spine and synapse stability. J Neurosci 27:7365–7376.CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 7365-7376
    • Alvarez, V.A.1    Ridenour, D.A.2    Sabatini, B.L.3
  • 3
    • 84899491806 scopus 로고    scopus 로고
    • Ionotropic NMDA receptor signaling is required for the induction of long-term depression in the mouse hippocampal CA1 region
    • CrossRef Medline
    • Babiec WE, Guglietta R, Jami SA, Morishita W, Malenka RC, O’Dell TJ (2014) Ionotropic NMDA receptor signaling is required for the induction of long-term depression in the mouse hippocampal CA1 region. J Neurosci 34:5285–5290.CrossRef Medline
    • (2014) J Neurosci , vol.34 , pp. 5285-5290
    • Babiec, W.E.1    Guglietta, R.2    Jami, S.A.3    Morishita, W.4    Malenka, R.C.5    O’Dell, T.J.6
  • 4
    • 84989915513 scopus 로고    scopus 로고
    • Calcium flux-independent NMDA receptor activity is required for Abeta oligomerinduced synaptic loss
    • CrossRef Medline
    • Birnbaum JH, Bali J, Rajendran L, Nitsch RM, Tackenberg C (2015) Calcium flux-independent NMDA receptor activity is required for Abeta oligomerinduced synaptic loss. Cell Death Dis 6:e1791.CrossRef Medline
    • (2015) Cell Death Dis , vol.6
    • Birnbaum, J.H.1    Bali, J.2    Rajendran, L.3    Nitsch, R.M.4    Tackenberg, C.5
  • 5
    • 0033769568 scopus 로고    scopus 로고
    • Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses
    • CrossRef Medline
    • Bolshakov VY, Carboni L, Cobb MH, Siegelbaum SA, Belardetti F (2000) Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses. Nat Neurosci 3:1107–1112.CrossRef Medline
    • (2000) Nat Neurosci , vol.3 , pp. 1107-1112
    • Bolshakov, V.Y.1    Carboni, L.2    Cobb, M.H.3    Siegelbaum, S.A.4    Belardetti, F.5
  • 7
    • 84900558583 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of dendritic spines in the living brain
    • CrossRef Medline
    • Chen CC, Lu J, Zuo Y (2014) Spatiotemporal dynamics of dendritic spines in the living brain. Front Neuroanat 8:28. CrossRef Medline
    • (2014) Front Neuroanat , vol.8
    • Chen, C.C.1    Lu, J.2    Zuo, Y.3
  • 10
    • 0029664973 scopus 로고    scopus 로고
    • Ca2+ signaling requirements for long-term depression in the hippocampus
    • CrossRef Medline
    • Cummings JA, Mulkey RM, Nicoll RA, Malenka RC (1996) Ca2+ signaling requirements for long-term depression in the hippocampus. Neuron 16: 825–833. CrossRef Medline
    • (1996) Neuron , vol.16 , pp. 825-833
    • Cummings, J.A.1    Mulkey, R.M.2    Nicoll, R.A.3    Malenka, R.C.4
  • 12
    • 65249130551 scopus 로고    scopus 로고
    • Uncoupling dendrite growth and patterning: Single-cell knockout analysis of NMDA receptor 2B
    • CrossRef Medline
    • Espinosa JS, Wheeler DG, Tsien RW, Luo L (2009) Uncoupling dendrite growth and patterning: single-cell knockout analysis of NMDA receptor 2B. Neuron 62:205–217.CrossRef Medline
    • (2009) Neuron , vol.62 , pp. 205-217
    • Espinosa, J.S.1    Wheeler, D.G.2    Tsien, R.W.3    Luo, L.4
  • 13
    • 79955029148 scopus 로고    scopus 로고
    • NMDA receptor subunit composition controls synaptogenesis and synapse stabilization
    • CrossRef Medline
    • Gambrill AC, Barria A (2011) NMDA receptor subunit composition controls synaptogenesis and synapse stabilization. Proc Natl Acad Sci U S A 108:5855–5860.CrossRef Medline
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 5855-5860
    • Gambrill, A.C.1    Barria, A.2
  • 14
    • 80052188595 scopus 로고    scopus 로고
    • Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: Single-cell NMDA receptor subunit deletion in vivo
    • CrossRef Medline
    • Gray JA, Shi Y, Usui H, During MJ, Sakimura K, Nicoll RA (2011) Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo. Neuron 71:1085–1101.CrossRef Medline
    • (2011) Neuron , vol.71 , pp. 1085-1101
    • Gray, J.A.1    Shi, Y.2    Usui, H.3    During, M.J.4    Sakimura, K.5    Nicoll, R.A.6
  • 16
    • 69249100460 scopus 로고    scopus 로고
    • Experience-dependent structural synaptic plasticity in the mammalian brain
    • CrossRef Medline
    • Holtmaat A, Svoboda K (2009) Experience-dependent structural synaptic plasticity in the mammalian brain. Nat Rev Neurosci 10:647-658.CrossRef Medline
    • (2009) Nat Rev Neurosci , vol.10 , pp. 647-658
    • Holtmaat, A.1    Svoboda, K.2
  • 17
    • 33845411954 scopus 로고    scopus 로고
    • AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss
    • CrossRef Medline
    • Hsieh H, Boehm J, Sato C, Iwatsubo T, Tomita T, Sisodia S, Malinow R (2006) AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 52:831-843.CrossRef Medline
    • (2006) Neuron , vol.52 , pp. 831-843
    • Hsieh, H.1    Boehm, J.2    Sato, C.3    Iwatsubo, T.4    Tomita, T.5    Sisodia, S.6    Malinow, R.7
  • 18
    • 84874629526 scopus 로고    scopus 로고
    • Metabotropic NMDA receptor function is required for beta-amyloid-induced synaptic depression
    • CrossRef Medline
    • Kessels HW, Nabavi S, Malinow R (2013) Metabotropic NMDA receptor function is required for beta-amyloid-induced synaptic depression. Proc Natl Acad Sci U S A 110:4033-4038.CrossRef Medline
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 4033-4038
    • Kessels, H.W.1    Nabavi, S.2    Malinow, R.3
  • 19
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarrassment of riches
    • CrossRef Medline
    • Malenka RC, Bear MF (2004) LTP and LTD: an embarrassment of riches. Neuron 44:5–21.CrossRef Medline
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 20
    • 0028176087 scopus 로고
    • Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression
    • CrossRef Medline
    • Mulkey RM, Endo S, Shenolikar S, Malenka RC (1994) Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature 369:486–488.CrossRef Medline
    • (1994) Nature , vol.369 , pp. 486-488
    • Mulkey, R.M.1    Endo, S.2    Shenolikar, S.3    Malenka, R.C.4
  • 21
    • 84874583038 scopus 로고    scopus 로고
    • Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression
    • CrossRef Medline
    • Nabavi S, Kessels HW, Alfonso S, Aow J, Fox R, Malinow R (2013) Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression. Proc Natl Acad Sci U S A 110:4027–4032.CrossRef Medline
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 4027-4032
    • Nabavi, S.1    Kessels, H.W.2    Alfonso, S.3    Aow, J.4    Fox, R.5    Malinow, R.6
  • 22
    • 9644265305 scopus 로고    scopus 로고
    • Bidirectional activity-dependent morphological plasticity in hippocampal neurons
    • CrossRef Medline
    • Nägerl UV, Eberhorn N, Cambridge SB, Bonhoeffer T (2004) Bidirectional activity-dependent morphological plasticity in hippocampal neurons. Neuron 44:759–767.CrossRef Medline
    • (2004) Neuron , vol.44 , pp. 759-767
    • Nägerl, U.V.1    Eberhorn, N.2    Cambridge, S.B.3    Bonhoeffer, T.4
  • 23
    • 79951811640 scopus 로고    scopus 로고
    • PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity
    • CrossRef Medline
    • Nakamura Y, Wood CL, Patton AP, Jaafari N, Henley JM, Mellor JR, Hanley JG (2011) PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity. EMBO J 30:719-730.CrossRef Medline
    • (2011) EMBO J , vol.30 , pp. 719-730
    • Nakamura, Y.1    Wood, C.L.2    Patton, A.P.3    Jaafari, N.4    Henley, J.M.5    Mellor, J.R.6    Hanley, J.G.7
  • 24
    • 0029664363 scopus 로고    scopus 로고
    • Postsynaptic levels of [Ca2_]i needed to trigger LTD and LTP
    • CrossRef Medline
    • Neveu D, Zucker RS (1996) Postsynaptic levels of [Ca2_]i needed to trigger LTD and LTP. Neuron 16:619–629.CrossRef Medline
    • (1996) Neuron , vol.16 , pp. 619-629
    • Neveu, D.1    Zucker, R.S.2
  • 25
    • 84872861536 scopus 로고    scopus 로고
    • Synapse-specific and size-dependent mechanisms of spine structural plasticity accompanying synaptic weakening
    • CrossRef Medline
    • Oh WC, Hill TC, Zito K (2013) Synapse-specific and size-dependent mechanisms of spine structural plasticity accompanying synaptic weakening. Proc Natl Acad Sci U S A 110:E305–E312.CrossRef Medline
    • (2013) Proc Natl Acad Sci U S A , vol.110
    • Oh, W.C.1    Hill, T.C.2    Zito, K.3
  • 26
    • 7044267351 scopus 로고    scopus 로고
    • Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity
    • CrossRef Medline
    • Okamoto K, Nagai T, Miyawaki A, Hayashi Y (2004) Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nat Neurosci 7:1104–1112.CrossRef Medline
    • (2004) Nat Neurosci , vol.7 , pp. 1104-1112
    • Okamoto, K.1    Nagai, T.2    Miyawaki, A.3    Hayashi, Y.4
  • 27
    • 0041458603 scopus 로고    scopus 로고
    • ScanImage: Flexible software for operating laser scanning microscopes
    • CrossRef Medline
    • Pologruto TA, Sabatini BL, Svoboda K (2003) ScanImage: flexible software for operating laser scanning microscopes. Biomed Eng Online 2:13.CrossRef Medline
    • (2003) Biomed Eng Online , vol.2
    • Pologruto, T.A.1    Sabatini, B.L.2    Svoboda, K.3
  • 28
    • 40249085825 scopus 로고    scopus 로고
    • Inhibition of Arp2/3- mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis
    • CrossRef Medline
    • Rocca DL, Martin S, Jenkins EL, Hanley JG (2008) Inhibition of Arp2/3- mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis. Nat Cell Biol 10:259–271.CrossRef Medline
    • (2008) Nat Cell Biol , vol.10 , pp. 259-271
    • Rocca, D.L.1    Martin, S.2    Jenkins, E.L.3    Hanley, J.G.4
  • 30
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • CrossRef Medline
    • Stoppini L, Buchs PA, Muller D (1991) A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37:173–182.CrossRef Medline
    • (1991) J Neurosci Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 31
    • 84878635884 scopus 로고    scopus 로고
    • NMDAreceptor activation but not ion flux is required for amyloid-beta induced synaptic depression
    • CrossRef Medline
    • Tamburri A, Dudilot A, Licea S, Bourgeois C, Boehm J (2013) NMDAreceptor activation but not ion flux is required for amyloid-beta induced synaptic depression. PLoS One 8:e65350.CrossRef Medline
    • (2013) Plos One , vol.8
    • Tamburri, A.1    Dudilot, A.2    Licea, S.3    Bourgeois, C.4    Boehm, J.5
  • 32
    • 37149006927 scopus 로고    scopus 로고
    • Regulation of spine morphology and spine density by NMDA receptor signaling in vivo
    • CrossRef Medline
    • Ultanir SK, Kim JE, Hall BJ, Deerinck T, Ellisman M, Ghosh A (2007) Regulation of spine morphology and spine density by NMDA receptor signaling in vivo. Proc Natl Acad Sci U S A 104:19553–19558.CrossRef Medline
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19553-19558
    • Ultanir, S.K.1    Kim, J.E.2    Hall, B.J.3    Deerinck, T.4    Ellisman, M.5    Ghosh, A.6
  • 33
    • 0034986665 scopus 로고    scopus 로고
    • A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux
    • CrossRef Medline
    • Vissel B, Krupp JJ, Heinemann SF, Westbrook GL (2001) A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux. Nat Neurosci 4:587–596.CrossRef Medline
    • (2001) Nat Neurosci , vol.4 , pp. 587-596
    • Vissel, B.1    Krupp, J.J.2    Heinemann, S.F.3    Westbrook, G.L.4
  • 34
    • 78650720266 scopus 로고    scopus 로고
    • Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning
    • CrossRef Medline
    • Volk L, Kim CH, Takamiya K, Yu Y, Huganir RL (2010) Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning. Proc Natl Acad Sci U S A 107:21784-21789.CrossRef Medline
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 21784-21789
    • Volk, L.1    Kim, C.H.2    Takamiya, K.3    Yu, Y.4    Huganir, R.L.5
  • 35
    • 84888090888 scopus 로고    scopus 로고
    • Long-term depression triggers the selective elimination of weakly integrated synapses
    • CrossRef Medline
    • Wiegert JS, Oertner TG (2013) Long-term depression triggers the selective elimination of weakly integrated synapses. Proc Natl Acad Sci U S A 110: E4510–E4519.CrossRef Medline
    • (2013) Proc Natl Acad Sci U S A , vol.110
    • Wiegert, J.S.1    Oertner, T.G.2
  • 36
    • 80052158080 scopus 로고    scopus 로고
    • Preparation of gene gun bullets and biolistic transfection of neurons in slice culture
    • CrossRef Medline
    • Woods G, Zito K (2008) Preparation of gene gun bullets and biolistic transfection of neurons in slice culture. J Vis Exp (12).pii: 675.CrossRef Medline
    • (2008) J Vis Exp , Issue.12
    • Woods, G.1    Zito, K.2
  • 37
    • 80052161487 scopus 로고    scopus 로고
    • Loss of PSD-95 enrichment is not a prerequisite for spine retraction
    • CrossRef Medline
    • Woods GF, Oh WC, Boudewyn LC, Mikula SK, Zito K (2011) Loss of PSD-95 enrichment is not a prerequisite for spine retraction. J Neurosci 31:12129-12138.CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 12129-12138
    • Woods, G.F.1    Oh, W.C.2    Boudewyn, L.C.3    Mikula, S.K.4    Zito, K.5
  • 38
    • 10044233862 scopus 로고    scopus 로고
    • A novel Ca2+- independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons
    • CrossRef Medline
    • Yang L, Mao L, Tang Q, Samdani S, Liu Z, Wang JQ (2004) A novel Ca2+- independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons. J Neurosci 24:10846-10857.CrossRef Medline
    • (2004) J Neurosci , vol.24 , pp. 10846-10857
    • Yang, L.1    Mao, L.2    Tang, Q.3    Samdani, S.4    Liu, Z.5    Wang, J.Q.6
  • 39
    • 0033031742 scopus 로고    scopus 로고
    • Selective induction of LTP and LTD by postsynaptic [Ca 2+]i elevation
    • Medline
    • Yang SN, Tang YG, Zucker RS (1999) Selective induction of LTP and LTD by postsynaptic [Ca 2+]i elevation. J Neurophysiol 81:781–787. Medline
    • (1999) J Neurophysiol , vol.81 , pp. 781-787
    • Yang, S.N.1    Tang, Y.G.2    Zucker, R.S.3
  • 40
    • 9644278075 scopus 로고    scopus 로고
    • Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses
    • CrossRef Medline
    • Zhou Q, Homma KJ, Poo MM (2004) Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses. Neuron 44: 749–757. CrossRef Medline
    • (2004) Neuron , vol.44 , pp. 749-757
    • Zhou, Q.1    Homma, K.J.2    Poo, M.M.3
  • 41
    • 0037162696 scopus 로고    scopus 로고
    • Ras and Rap control AMPA receptor trafficking during synaptic plasticity
    • CrossRef Medline
    • Zhu JJ, Qin Y, Zhao M, Van Aelst L, Malinow R (2002) Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110:443-455. CrossRef Medline
    • (2002) Cell , vol.110 , pp. 443-455
    • Zhu, J.J.1    Qin, Y.2    Zhao, M.3    Van Aelst, L.4    Malinow, R.5
  • 42
    • 22444441508 scopus 로고    scopus 로고
    • Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex
    • CrossRef Medline
    • Zuo Y, Yang G, Kwon E, Gan WB (2005) Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex. Nature 436:261–265. CrossRef Medline
    • (2005) Nature , vol.436 , pp. 261-265
    • Zuo, Y.1    Yang, G.2    Kwon, E.3    Gan, W.B.4


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