Etiologies and Short-Term Mortality in Patients with Ultraelevated Serum Ferritin

Southern Medical Journal

Volumn 108, Issue 9, 2015, Pages 574-578

  Beer, Timothy ^a   Vadakara, Joseph ^a  

^a GEISINGER MEDICAL CENTER   (United States)

Author keywords

ferritin; hemophagocytic lymphohistiocytosis; hereditary hemochromatosis; hyperferritinemia

Indexed keywords

FERRITIN;

ADULT; AGED; ARTICLE; BLOOD TRANSFUSION; CONTROLLED STUDY; END STAGE RENAL DISEASE; FEMALE; FERRITIN BLOOD LEVEL; HEMOPHAGOCYTIC SYNDROME; HUMAN; HYPERFERRITINEMIA; INFLAMMATION; IRON OVERLOAD; LIVER INJURY; MACROPHAGE ACTIVATION SYNDROME; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASTIC SYNDROME; RETROSPECTIVE STUDY; SURVIVAL; ULTRAHYPERFERRITINEMIA; VERY ELDERLY; ACUTE LUNG INJURY; ADVERSE EFFECTS; BLOOD; CHRONIC KIDNEY FAILURE; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KIDNEY DISEASE; LIVER DISEASE; NEOPLASM; STATISTICS AND NUMERICAL DATA;

ACUTE LUNG INJURY; BLOOD TRANSFUSION; FERRITINS; HIV INFECTIONS; HUMANS; IRON OVERLOAD; KIDNEY DISEASES; KIDNEY FAILURE, CHRONIC; LIVER DISEASES; MYELODYSPLASTIC SYNDROMES; NEOPLASMS; RETROSPECTIVE STUDIES;

EID: 84940901367     PISSN: 00384348     EISSN: 15418243     Source Type: Journal    
DOI: 10.14423/SMJ.0000000000000339     Document Type: Article

References (11)

1. Theil EC,. Ferritin: structure, gene regulation, and cellular function in animals, plants, and microorganisms. Annu Rev Biochem 1987; 56: 289-315.
2. Tran TN, Eubanks SK, Schaffer KJ, Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron. Blood 1997; 90: 4979-4986.
3. Guyatt GH, Oxman AD, Ali M, Laboratory diagnosis of iron-deficiency anemia: an overview. J Gen Intern Med 1992; 7: 145-153.
4. Wish JB,. Assessing iron status: beyond serum ferritin and transferrin saturation. Clin J Am Soc Nephrol 2006; 1 (Suppl 1): S4-S8.
5. Lee MH, Means RT Jr,. Extremely elevated serum ferritin levels in a university hospital: associated diseases and clinical significance. Am J Med 1995; 98: 566-571.
6. Moore C Jr, Ormseth M, Fuchs H,. Causes and significance of markedly elevated serum ferritin levels in an academic medical center. J Clin Rheumatol 2013; 19: 324-328.
7. Crook MA, Walker PL,. Extreme hyperferritinaemia: clinical causes. J Clin Pathol 2013; 66: 438-440.
8. Kalantar-Zadeh K, Regidor DL, McAllister CJ, Time-dependent associations between iron and mortality in hemodialysis patients. J Am Soc Nephrol 2005; 16: 3070-3080.
9. Ellervik C, Marott JL, Tybjærg-Hansen A, Total and cause-specific mortality by moderately and markedly increased ferritin concentrations: general population study and metaanalysis. Clin Chem 2014; 60: 1419-1428.
10. Kalousová M, Krechler T, Jáchymová M, Ferritin as an independent mortality predictor in patients with pancreas cancer: results of a pilot study. Tumour Biol 2012; 33: 1695-1700.
11. Milman N, Pedersen LM,. The serum ferritin concentration is a significant prognostic indicator of survival in primary lung cancer. Oncol Rep 2002; 9: 193-198.