Label-Free Electrochemiluminescent Immunosensor for Detection of Carcinoembryonic Antigen Based on Nanocomposites of GO/MWCNTs-COOH/Au@CeO2

ACS Applied Materials and Interfaces

Volumn 7, Issue 34, 2015, Pages 19260-19267

  Pang, Xuehui ^a   Li, Jianxiu ^a   Zhao, Yongbei ^a   Wu, Dan ^a   Zhang, Yong ^a   Du, Bin ^a   Ma, Hongmin ^a   Wei, Qin ^a  

^a UNIVERSITY OF JINAN   (China)

Author keywords

cancer biomarker; carbon nanomaterials; electrochemiluminescence; label free immunosensor; modified electrodes

Indexed keywords

ANTIGENS; CERIUM OXIDE; GLASS MEMBRANE ELECTRODES; GOLD DEPOSITS; GOLD NANOPARTICLES; GRAPHENE; MULTIWALLED CARBON NANOTUBES (MWCN); NANOCOMPOSITES; NANOPARTICLES; SIGNAL TO NOISE RATIO; YARN;

CANCER BIOMARKERS; CARBON NANO-MATERIALS; ELECTROCHEMILUMINESCENCE; LABEL-FREE IMMUNOSENSOR; MODIFIED ELECTRODES;

IMMUNOSENSORS;

CARBON NANOTUBE; CARCINOEMBRYONIC ANTIGEN; CERIC OXIDE; CERIUM; GOLD; GRAPHITE; NANOCOMPOSITE;

BLOOD; CHEMISTRY; ELECTROCHEMICAL ANALYSIS; GENETIC PROCEDURES; HUMAN; LUMINESCENCE; PH; PROCEDURES; REPRODUCIBILITY; ULTRASTRUCTURE;

BIOSENSING TECHNIQUES; CARCINOEMBRYONIC ANTIGEN; CERIUM; ELECTROCHEMICAL TECHNIQUES; GOLD; GRAPHITE; HUMANS; HYDROGEN-ION CONCENTRATION; LUMINESCENT MEASUREMENTS; NANOCOMPOSITES; NANOTUBES, CARBON; REPRODUCIBILITY OF RESULTS;

EID: 84940859825     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b05185     Document Type: Article

References (59)

1. Ji, J.; He, L.; Shen, Y.; Hu, P.; Li, X.; Jiang, L. P.; Zhang, J. R.; Li, L. L.; Zhu, J. J. High-efficient Energy Funneling Based on Electrochemiluminescence Resonance Energy Transfer in Graded-gap Quantum Dots Bilayers for Immunoassay Anal. Chem. 2014, 86, 3284-3290 10.1021/ac500351d
2. Jie, G.; Wang, L.; Yuan, J.; Zhang, S. Versatile Electrochemiluminescence Assays for Cancer Cells Based on Dendrimer/CdSe-ZnS-quantum Dot Nanoclusters Anal. Chem. 2011, 83, 3873-3880 10.1021/ac200383z
3. Ding, C. C.; Zheng, Q.; Wang, N.; Yue, Q. An Electrochemiluminescence Strategy Based on Aptamers and Nanoparticles for the Detection of Cancer Cells Anal. Chim. Acta 2012, 756, 73-78 10.1016/j.aca.2012.10.023
4. Ding, C. C.; Wei, S.; Liu, H. Electrochemiluminescent Determination of Cancer Cells Based on Aptamers, Nanoparticles, and Magnetic Beads Chem.-Eur. J. 2012, 18, 7263-7268 10.1002/chem.201104019
5. 2+/tripropylamine While Preserving Optical Transparency of Indium Tin Oxide for Sensitive Electrochemiluminescence-based Analyses Anal. Chem. 2014, 86, 1654-1660 10.1021/ac403415m
6. Li, F.; Cui, H. A Label-free Electrochemiluminescence Aptasensor for Thrombin Based on Novel Assembly Strategy of Oligonucleotide and Luminol Functionalized Gold Nanoparticles Biosens. Bioelectron. 2013, 39, 261-267 10.1016/j.bios.2012.07.060
7. Jie, G. F.; Liu, B.; Miao, J. J.; Zhu, J. J. Electrogenerated Chemiluminescence from CdS Nanotubes and Its Sensing Application in Aqueous Solution Talanta 2007, 71, 1476-1480 10.1016/j.talanta.2006.07.029
8. Ren, T.; Xu, J. Z.; Tu, Y. F.; Xu, S.; Zhu, J. J. Electrogenerated Chemiluminescence of CdS Spherical Assemblies Electrochem. Commun. 2005, 7, 5-9 10.1016/j.elecom.2004.10.005
9. Jie, G.; Zhang, J.; Wang, D.; Cheng, C.; Chen, H. Y.; Zhu, J. J. Electrochemiluminescence Immunosensor Based on CdSe Nanocomposites Anal. Chem. 2008, 80, 4033-4039 10.1021/ac800052g
10. Liu, B.; Ren, T.; Zhang, J. R.; Chen, H. Y.; Zhu, J. J.; Burda, C. Spectroelectrochemistry of Hollow Spherical CdSe Quantum Dot Assemblies in Water Electrochem. Commun. 2007, 9, 551-557 10.1016/j.elecom.2006.10.030
11. Liu, X.; Jiang, H.; Lei, J.; Ju, H. X. Anodic Electrochemiluminescence of CdTe Quantum Dots and Its Energy Transfer for Detection of Catechol Derivatives Anal. Chem. 2007, 79, 8055-8060 10.1021/ac070927i
12. Ding, C. C.; Zhong, H.; Zhang, S. S. Ultrasensitive Flow Injection Chemiluminescence Detection of DNA Hybridization Using NanoCuS Tags Biosens. Bioelectron. 2008, 23, 1314-1318 10.1016/j.bios.2007.12.005
13. Geng, J.; Jia, X. D.; Zhu, J. J. Sonochemical Selective Synthesis of ZnO/CdS Core/shell Nanostructures and Their Optical Properties CrystEngComm 2011, 13, 193-198 10.1039/C0CE00180E
14. Kaushik, A.; Solanki, P. R.; Pandey, M.; Ahmad, S.; Malhotra, B. D. Cerium Oxide-chitosan Based Nanobiocomposite for Food Borne Mycotoxin Detection Appl. Phys. Lett. 2009, 95, 173703-3 10.1063/1.3249586
15. 2 with 1-furoylthioureas: Preconcentration and Voltammetric Behavior of Cd (II) at Carbon Paste Electrodes Modified with 3-monosubstituted and 3, 3-disubstituted Derivatives Sens. Actuators, B 2007, 120, 766-772 10.1016/j.snb.2006.03.042
16. Kaushik, A.; Solanki, P. R.; Ansari, A. A.; Ahmad, S.; Malhotra, B. D. Chitosan-iron Oxide Nanobiocomposite Based Immunosensor for Ochratoxin-A Electrochem. Commun. 2008, 10, 1364-1368 10.1016/j.elecom.2008.07.007
17. 2 Catalyst with Improved Performance for Methanol Electro-oxidation by β-cyclodextrin Carbonization Adv. Mater. 2011, 23, 3100-3104 10.1002/adma.201100040
18. Qiu, J. D.; Cui, S. G.; Liang, R. P. Hydrogen Peroxide Biosensor Based on the Direct Electrochemistry of Myoglobin Immobilized on Ceria Nanoparticles Coated with Multiwalled Carbon Nanotubesby a Hydrothermal Synthetic Method Microchim. Acta 2010, 171, 333-339 10.1007/s00604-010-0440-z
19. Saha, S.; Arya, S. K.; Singh, S.; Sreenivas, K.; Malhotra, B.; Gupta, V. Nanoporous Cerium Oxide Thin Film for Glucose Biosensor Biosens. Bioelectron. 2009, 24, 2040-2045 10.1016/j.bios.2008.10.032
20. Peng, L.; Feng, Y.; Lv, P.; Lei, D.; Shen, Y.; Li, Y.; Feng, W. Transparent, Conductive, and Flexible Multiwalled Carbon Nanotube/graphene Hybrid Electrodes with Two Three-dimensional Microstructures J. Phys. Chem. C 2012, 116, 4970-4978 10.1021/jp209180j
21. Cheng, Q.; Tang, J.; Ma, J.; Zhang, H.; Shinya, N.; Qin, L. C. Graphene and Carbon Nanotube Composite Electrodes for Supercapacitors with Ultra-high Energy Density Phys. Chem. Chem. Phys. 2011, 13, 17615-17624 10.1039/c1cp21910c
22. 2 Ternary Nanocomposites with Electrochemical Performance J. Mater. Chem. A 2014, 2, 18480-18487 10.1039/C4TA03996C
23. Rakhi, R.; Alshareef, H. Enhancement of the Energy Storage Properties of Supercapacitors Using Graphene Nanosheets Dispersed with Metal Oxide-loaded Carbon Nanotubes J. Power Sources 2011, 196, 8858-8865 10.1016/j.jpowsour.2011.06.038
24. 2-graphene-carbon Nanotube Mixture for Anode Material with Improved Rate Capacities Carbon 2011, 49, 4524-4534 10.1016/j.carbon.2011.06.059
25. 2 as High-rate Electrode Materials for Supercapacitors J. Electroanal. Chem. 2012, 684, 32-37 10.1016/j.jelechem.2012.08.024
26. Lota, G.; Fic, K.; Frackowiak, E. Carbon Nanotubes and Their Composites in Electrochemical Applications Energy Environ. Sci. 2011, 4, 1592-1605 10.1039/c0ee00470g
27. Kim, Y. T.; Tadai, K.; Mitani, T. Highly Dispersed Ruthenium Oxide Nanoparticles on Carboxylated Carbon Nanotubes for Supercapacitor Electrode Materials J. Mater. Chem. 2005, 15, 4914-4921 10.1039/b511869g
28. Jie, G.; Liu, P.; Wang, L.; Zhang, S. S. Electrochemiluminescence Immunosensor Based on Nanocomposite Film of CdS Quantum Dots-carbon Nanotubes Combined with Gold Nanoparticles-chitosan Electrochem. Commun. 2010, 12, 22-26 10.1016/j.elecom.2009.10.027
29. Tang, D.; Yuan, R.; Chai, Y. Ultrasensitive Electrochemical Immunosensor for Clinical Immunoassay Using Thionine-doped Magnetic Gold Nanospheres as Labels and Horseradish Peroxidase as Enhancer Anal. Chem. 2008, 80, 1582-1588 10.1021/ac702217m
30. Rusling, J. F.; Sotzing, G.; Papadimitrakopoulosa, F. Designing Nanomaterial-enhanced Electrochemical Immunosensors for Cancer Biomarker Proteins Bioelectrochemistry 2009, 76, 189-194 10.1016/j.bioelechem.2009.03.011
31. Li, C.; Lin, J.; Guo, Y.; Zhang, S. S. A Novel Electrochemiluminescent Reagent of Cyclometalated Iridium Complex-based DNA Biosensor and Its Application in Cancer Cell Detection Chem. Commun. 2011, 47, 4442-4444 10.1039/c1cc10544b
32. Hu, M.; Yan, J.; He, Y.; Lu, H. T.; Weng, L. X.; Song, S. P.; Fan, C. H.; Wang, L. H. Ultrasensitive, Multiplexed Detection of Cancer Biomarkers Directly in Serum by Using a Quantum Dot-Based Microfluidic Protein Chip ACS Nano 2009, 4, 488-494 10.1021/nn901404h
33. Huang, K. H. G.; Bonsall, D.; Katzourakis, A.; Thomson, E. C.; Fidler, S. J.; Main, J.; Muir, D.; Weber, J. N.; Frater, A. J.; Phillips, R. E.; Pybus, O. G.; Goulder, J. R.; Mclure, M. O.; Cooke, G. S.; Klenerman, P. B-cell Depletion Reveals a Role for Antibodies in the Control of Chronic HIV-1 Infection Nat. Commun. 2010, 1, 102 10.1038/ncomms1100
34. Naghibalhossaini, F.; Ebadi, P. Evidence for CEA Release from Human Colon Cancer Cells by an Endogenous GPI-PLD Enzyme Cancer Lett. 2006, 234, 158-167 10.1016/j.canlet.2005.03.028
35. Li, R.; Feng, F.; Chen, Z. Z.; Bai, Y. F.; Guo, F. F.; Wu, F. Y.; Zhou, G. Sensitive Detection of Carcinoembryonic Antigen Using Surface Plasmon Resonance Biosensor with Gold Nanoparticles Signal Amplification Talanta 2015, 140, 143-149 10.1016/j.talanta.2015.03.041
36. Giljohann, D. A.; Seferos, D. S.; Patel, P. C.; Millstone, J. E.; Rosi, N. L.; Mirkin, C. A. Oligonucleotide Loading Determines Cellular Uptake of DNA-modified Gold Nanoparticles Nano Lett. 2007, 7, 3818-3821 10.1021/nl072471q
37. Souza, G. R.; Christianson, D. R.; Staquicini, F. I.; Ozawa, M. G.; Snyder, E. Y.; Sidman, R. L. Networks of Gold Nanoparticles and Bacteriophage as Biological Sensors and Cell-targeting Agents Proc. Natl. Acad. Sci. U. S. A. 2006, 103, 1215-1220 10.1073/pnas.0509739103
38. Murphy, C. J.; Gole, A. M.; Stone, J. W.; Sisco, P. N.; Alkilany, A. M.; Goldsmith, E. C. Gold Nanoparticles in Biology: Beyond Toxicity to Cellular Imaging Acc. Chem. Res. 2008, 41, 1721-1730 10.1021/ar800035u
39. Marcano, D. C.; Kosynkin, D. V.; Berlin, J. M.; Sinitskii, A.; Sun, Z.; Slesarev, A.; Alemany, L. B.; Lu, W.; Tour, J. M. Improved Synthesis of Graphene Oxide ACS Nano 2010, 4, 4806-4814 10.1021/nn1006368
40. Muzzarelli, R. A.; Tanfani, F.; Scarpini, G. Chelating, Film-forming, and Coagulating Ability of the Chitosan-glucan Complex from Aspergillus Niger Industrial Wastes Biotechnol. Bioeng. 1980, 22, 885-896 10.1002/bit.260220412
41. Huang, H.; Yang, X. Chitosan Mediated Assembly of Gold Nanoparticles Multilayer Colloids Surf., A 2003, 226, 77-86 10.1016/S0927-7757(03)00382-0
42. 2-Au Junctions J. Phys.: Condens. Matter 2008, 20, 374101 10.1088/0953-8984/20/37/374101
43. Song, H. Q.; Zhu, Q.; Zheng, X. J.; Chen, X. G. One-step Synthesis of Three-dimensional Graphene/multiwalled Carbon Nanotubes/Pd Composite Hydrogels: an Efficient Recyclable Catalyst for Suzuki Coupling Reactions J. Mater. Chem. A 2015, 3, 10368-10377 10.1039/C5TA00280J
44. Chen, S.; Yeoh, W.; Liu, Q.; Wang, G. Chemical-free Synthesis of Graphene-carbon Anotube Hybrid Materials for Reversible Lithium Storage in Lithium-ion Batteries Carbon 2012, 50, 4557-4565 10.1016/j.carbon.2012.05.040
45. Zhang, J.; Zou, H.; Qing, Q.; Yang, Y.; Li, Q.; Liu, Z.; Guo, X. Y.; Du, Z. L. Effect of Chemical Oxidation on the Structure of Single-walled Carbon Nanotubes J. Phys. Chem. B 2003, 107, 3712-3718 10.1021/jp027500u
46. 2/MWCNT Nanocomposite Modified Carbon Paste Electrode for Amplified Electrochemical Sensing of Uric Acid Mater. Sci. Eng., C 2014, 36, 160-167 10.1016/j.msec.2013.12.014
47. Huang, H.; Ran, P.; Liu, Z. Impedance Sensing of Allergen-antibody Interaction on Glassy Carbon Electrode Modified by Gold Electrodeposition Bioelectrochemistry 2007, 70, 257-262 10.1016/j.bioelechem.2006.10.002
48. Yang, L.; Li, Y. AFM and Impedance Spectroscopy Characterization of the Immobilization of Antibodies on Indium-tin Oxide Electrode Through Self-assembled Monolayer of Epoxysilane and Their Capture of Escherichia Coli O157: H7 Biosens. Bioelectron. 2005, 20, 1407-1416 10.1016/j.bios.2004.06.024
49. Lu, Q.; Wei, W.; Zhou, Z. X.; Zhou, Z. X.; Zhang, Y. J.; Liu, S. Q. Electrochemiluminescence Resonance Energy Transfer Between Graphene Quantum Dots and Gold Nanoparticles for DNA Damage Detection Analyst 2014, 139, 2404-2410 10.1039/c4an00020j
50. Qian, J.; Zhang, C. Y.; Cao, X. D.; Liu, S. Q. Versatile Immunosensor Using a Quantum Dot Coated Silica Nanosphere as a Label for Signal Amplification Anal. Chem. 2010, 82, 6422-6429 10.1021/ac100558t
51. Zou, G.; Ju, H. X. Electrogenerated Chemiluminescence from a CdSe Nanocrystal Film and Its Sensing Application in Aqueous Solution Anal. Chem. 2004, 76, 6871-6876 10.1021/ac049012j
52. 2+ Anal. Chem. 2012, 84, 4754-4759 10.1021/ac300205w
53. Liu, R.; Liu, X.; Tang, Y.; Wu, L.; Hou, X.; Lv, Y. Highly Sensitive Immunoassay Based on Immunogold-silver Amplification and Inductively Coupled Plasma Mass Spectrometric Detection Anal. Chem. 2011, 83, 2330-2336 10.1021/ac103265z
54. 2 Hybrid Nanocomposite Film J. Colloid Interface Sci. 2010, 348, 108-113 10.1016/j.jcis.2010.04.012
55. Dungchai, W.; Siangproh, W.; Lin, J. M.; Chailapakul, O.; Lin, S.; Ying, X. Development of a Sensitive Micro-magnetic Chemiluminescence Enzyme Immunoassay for the Determination of Carcinoembryonic Antigen Anal. Bioanal. Chem. 2007, 387, 1965-1971 10.1007/s00216-006-0899-y
56. Cao, X.; Wang, N.; Jia, S.; Guo, L.; Li, K. Bimetallic AuPt Nanochains: Synthesis and Their Application in Eelectrochemical Immunosensor for the Detection of Carcinoembryonic Antigen Biosens. Bioelectron. 2013, 39, 226-230 10.1016/j.bios.2012.07.046
57. Huang, G.; Deng, B.; Xi, Q.; Tao, C.; Ye, L. Surface Modification of Superparamagnetic Magnetite Nanoparticles and Its Application for Detection of Anti-CEA Using Electrochemiluminescent Immunosensor Med. Chem. 2015, 5, 050-057 10.4172/2161-0444.1000242
58. Yan, J.; Song, S.; Li, B.; Zhang, Q. Z.; Huang, Q.; Zhang, H.; Fan, C. H. An On-nanoparticle Rolling-circle Amplification Platform for Ultrasensitive Protein Detection in Biological Fluids Small 2010, 6, 2520-2525 10.1002/smll.201001220
59. Hu, M.; He, Y.; Song, S.; Yan, J.; Lu, H. T.; Weng, L. X.; Wang, L. H.; Fan, C. H. DNA-bridged Bioconjugation of Fluorescent Quantum Dots for Highly Sensitive Microfluidic Protein Chips Chem. Commun. 2010, 46, 6126-6128 10.1039/c0cc01608j