Study of the T16189C variant and mitochondrial lineages in Tunisian and overall mediterranean region

Mitochondrial DNA

Volumn 27, Issue 2, 2016, Pages 1558-1563

  Hsouna, Sana ^a   Ben Halim, Nizar ^a   Lasram, Khaled ^a   Meiloud, Ghlana ^b   Arfa, Imen ^a   Kerkeni, Emna ^c   Romdhane, Lilia ^a   Jamoussi, Henda ^a   Bahri, Sonia ^a   Ammar, Slim Ben ^a   Abid, Abdelmajid ^a,d   Barakat, Abdelhamid ^e   Houmeida, Ahmed ^b   Abdelhak, Sonia ^a   Kefi, Rym ^a  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b Faculte des Sciences et Techniques   (Mauritania)

^c UNIVERSITY OF MONASTIR   (Tunisia)

^d Institut National de Nutrition Tunis   (Tunisia)

^e Institut Pasteur du Maroc   (Morocco)

Author keywords

Mediterranenan populations; Mitochondrial haplogroups; Principal component analysis; T16189C; Tunisia

Indexed keywords

MITOCHONDRIAL DNA;

ARTICLE; BERBER; BLOOD SAMPLING; DNA SEQUENCE; GENE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC VARIABILITY; HAPLOGROUP; HUMAN; MITOCHONDRIAL HAPLOGROUP; NORTH AFRICAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; T16189C GENE; TUNISIAN; CHEMISTRY; GENETIC VARIATION; HAPLOTYPE; PRINCIPAL COMPONENT ANALYSIS; SOUTHERN EUROPE; TUNISIA;

DNA, MITOCHONDRIAL; GENETIC VARIATION; HAPLOTYPES; HUMANS; MEDITERRANEAN REGION; PRINCIPAL COMPONENT ANALYSIS; SEQUENCE ANALYSIS, DNA; TUNISIA;

EID: 84940764911     PISSN: 19401736     EISSN: 19401744     Source Type: Journal    
DOI: 10.3109/19401736.2014.953136     Document Type: Article

References (41)

1. Alvarez-Iglesias V, Mosquera-Miguel A, Cerezo M, Quintans B, Zarrabeitia MT, Cusco I, Lareu MV, et al. (2009). New population and phylogenetic features of the internal variation within mitochondrial DNA macro-haplogroup R0. PLoS One 4:e5112.
2. Anderson S, Bankier AT, Barrell BG, de Bruijn MH, Coulson AR, Drouin J, Eperon IC, et al. (1981). Sequence and organization of the human mitochondrial genome. Nature 290:457–65.
3. Bertranpetit J, Sala J, Calafell F, Underhill PA, Moral P, Comas D. (1995). Human mitochondrial DNA variation and the origin of Basques. Ann Hum Genet 59:63–81.
4. Brakez Z, Bosch E, Izaabel H, Akhayat O, Comas D, Bertranpetit J, Calafell F. (2001). Human mitochondrial DNA sequence variation in the Moroccan population of the Souss area. Ann Hum Biol 28: 295–307.
5. Cherni L, Fernandes V, Pereira JB, Costa MD, Goios A, Frigi S, Yacoubi- Loueslati B, et al. (2009). Post-last glacial maximum expansion from Iberia to North Africa revealed by fine characterization of mtDNA H haplogroup in Tunisia. Am J Phys Anthropol 139:253–60.
6. Corte-Real HB, Macaulay VA, Richards MB, Hariti G, Issad MS, Cambon-Thomsen A, Papiha S, et al. (1996). Genetic diversity in the Iberian Peninsula determined from mitochondrial sequence analysis. Ann Hum Genet 60:331–50.
7. Coudray C, Olivieri A, Achilli A, Pala M, Melhaoui M, Cherkaoui M, El-Chennawi F, et al. (2009). The complex and diversified mitochondrial gene pool of Berber populations. Ann Hum Genet 73:196–214.
8. Di Rienzo A, Wilson AC. (1991). Branching pattern in the evolutionary tree for human mitochondrial DNA. Proc Natl Acad Sci USA 88: 1597–601.
9. Dubut V, Chollet L, Murail P, Cartault F, Beraud-Colomb E, Serre M, Mogentale-Profizi N. (2004). mtDNA polymorphisms in five French groups: Importance of regional sampling. Eur J Hum Genet 12: 293–300.
10. Ennafaa H, Fregel R, Khodjet-El-Khil H, Gonzalez AM, Mahmoudi HA, Cabrera VM, Larruga JM, et al. (2011). Mitochondrial DNA and Y-chromosome microstructure in Tunisia. J Hum Genet 56:734–41.
11. Fadhlaoui-Zid K, Plaza S, Calafell F, Ben Amor M, Comas D, Bennamar Elgaaied A. (2004). Mitochondrial DNA heterogeneity in Tunisian Berbers. Ann Hum Genet 68:222–33.
12. Fadhlaoui-Zid K, Rodriguez-Botigue L, Naoui N, Benammar-Elgaaied A, Calafell F, Comas D. (2011). Mitochondrial DNA structure in North Africa reveals a genetic discontinuity in the Nile Valley. Am J Phys Anthropol 145:107–17.
13. Falchi A, Giovannoni L, Calo CM, Piras IS, Moral P, Paoli G, Vona G, et al. (2006). Genetic history of some western Mediterranean human isolates through mtDNA HVR1 polymorphisms. J Hum Genet 51:9–14.
14. Francalacci P, Bertranpetit J, Calafell F, Underhill PA. (1996). Sequence diversity of the control region of mitochondrial DNA in Tuscany and its implications for the peopling of Europe. Am J Phys Anthropol 100: 443–60.
15. Hsouna S, Ben Halim N, Lasram K, Arfa I, Jamoussi H, Bahri S, Ammar SB, et al. (2013). Association study of mitochondrial DNA polymorphisms with type 2 diabetes in Tunisian population. Mitochondrial DNA. [Epub ahead of print]. doi: 10.3109/19401736.2013.836508.
16. Ingman M, Kaessmann H, Paabo S, Gyllensten U. (2000). Mitochondrial genome variation and the origin of modern humans. Nature 408: 708–13.
17. Irwin J, Saunier J, Strouss K, Paintner C, Diegoli T, Sturk K, Kovatsi L, et al. (2008). Mitochondrial control region sequences from northern Greece and Greek Cypriots. Int J Legal Med 122:87–9.
18. Kefi R. (2011). Ancient DNA investigations: A review on their significance in different research fields. Int J Mod Anthrop 4:61–76.
19. Kefi R, Hsouna S, Ben Halim N, Lasram K, Romdhane L, Messai H, Abdelhak S. (2014). Phylogeny and genetic structure of Tunisians and their position within Mediterranean populations. Mitochondrial DNA. [Epub ahead of print]. doi: 10.3109/19401736.2013.879649.
20. Khodjet-el-Khil H, Fadhlaoui-Zid K, Cherni L, Phillips C, Fondevila M, Carracedo A, Ben Ammar-Elgaaied A. (2011). Genetic analysis of the SNPforID 34-plex ancestry informative SNP panel in Tunisian and Libyan populations. Forensic Sci Int Genet 5:e45–7.
21. Khogali SS, Mayosi BM, Beattie JM, McKenna WJ, Watkins H, Poulton J. (2001). A common mitochondrial DNA variant associated with susceptibility to dilated cardiomyopathy in two different populations. Lancet 357:1265–7.
22. Livesey KJ, Wimhurst VL, Carter K, Worwood M, Cadet E, Rochette J, Roberts AG, et al. (2004). The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading. J Med Genet 41:6–10.
23. Loueslati BY, Cherni L, Khodjet-Elkhil H, Ennafaa H, Pereira L, Amorim A, Ben Ayed F, et al. (2006). Islands inside an island: reproductive isolates on Jerba island. Am J Hum Biol 18:149–53.
24. Macaulay V, Richards M, Hickey E, Vega E, Cruciani F, Guida V, Scozzari R, et al. (1999). The emerging tree of West Eurasian mtDNAs: A synthesis of control-region sequences and RFLPs. Am J Hum Genet 64:232–49.
25. Meiloud G, Arfa I, Kefi R, Abdelhamid I, Veten F, Lasram K, Ben Halim N, et al. (2013). Type 2 diabetes in Mauritania: Prevalence of the undiagnosed diabetes, influence of family history and maternal effect. Prim Care Diabetes 7:19–24.
26. Mohlke KL, Jackson AU, Scott LJ, Peck EC, Suh YD, Chines PS, Watanabe RM, et al. (2005). Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns. Hum Genet 118:245–54.
27. Ottoni C, Martinez-Labarga C, Loogvali EL, Pennarun E, Achilli A, De Angelis F, Trucchi E, et al. (2009). First genetic insight into Libyan Tuaregs: A maternal perspective. Ann Hum Genet 73:438–48.
28. Park KS, Chan JC, Chuang LM, Suzuki S, Araki E, Nanjo K, Ji L, et al. (2008). A mitochondrial DNA variant at position 16189 is associated with type 2 diabetes mellitus in Asians. Diabetologia 51:602–8.
29. Picornell A, Gomez-Barbeito L, Tomas C, Castro JA, Ramon MM. (2005). Mitochondrial DNA HVRI variation in Balearic populations. Am J Phys Anthropol 128:119–30.
30. Plaza S, Calafell F, Helal A, Bouzerna N, Lefranc G, Bertranpetit J, Comas D. (2003). Joining the pillars of Hercules: mtDNA sequences show multidirectional gene flow in the western Mediterranean. Ann Hum Genet 67:312–28.
31. Poulton J, Luan J, Macaulay V, Hennings S, Mitchell J, Wareham NJ. (2002). Type 2 diabetes is associated with a common mitochondrial variant: Evidence from a population-based case-control study. Hum Mol Genet 11:1581–3.
32. Richards M, Macaulay V, Hickey E, Vega E, Sykes B, Guida V, Rengo C, et al. (2000). Tracing European founder lineages in the Near Eastern mtDNA pool. Am J Hum Genet 67:1251–76.
33. Salas A, Comas D, Lareu MV, Bertranpetit J, Carracedo A. (1998). mtDNA analysis of the Galician population: A genetic edge of European variation. Eur J Hum Genet 6:365–75.
34. Saunier JL, Irwin JA, Strouss KM, Ragab H, Sturk KA, Parsons TJ. (2009). Mitochondrial control region sequences from an Egyptian population sample. Forensic Sci Int Genet 3:e97–103.
35. Schapira AH. (2006). Mitochondrial disease. Lancet 368:70–82.
36. Stevanovitch A, Gilles A, Bouzaid E, Kefi R, Paris F, Gayraud RP, Spadoni JL, et al. (2004). Mitochondrial DNA sequence diversity in a sedentary population from Egypt. Ann Hum Genet 68:23–39.
37. Turchi C, Buscemi L, Giacchino E, Onofri V, Fendt L, Parson W, Tagliabracci A. (2009). Polymorphisms of mtDNA control region in Tunisian and Moroccan populations: an enrichment of forensic mtDNA databases with Northern Africa data. Forensic Sci Int Genet 3:166–72.
38. van Oven M, Kayser M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat 30: E386–94.
39. Varesi L, Memmi M, Cristofari MC, Mameli GE, Calo CM, Vona G. (2000). Mitochondrial control-region sequence variation in the Corsican population, France. Am J Hum Biol 12:339–51.
40. Villems R. (2011). Homo sapiens Mitochondrial DNA D-Loop HVR1 sequence. Available at: http://www.ncbi.nlm.nih.gov/nuccore (accession numbers AJ274757–AJ274942). (Accessed 22 August 2014).
41. Weng SW, Liou CW, Lin TK, Wei YH, Lee CF, Eng HL, Chen SD, et al. (2005). Association of mitochondrial deoxyribonucleic acid 16189 variant (T-4C transition) with metabolic syndrome in Chinese adults. J Clin Endocrinol Metab 90:5037–40.