Aberrant white matter networks mediate cognitive impairment in patients with silent lacunar infarcts in basal ganglia territory

Journal of Cerebral Blood Flow and Metabolism

Volumn 35, Issue 9, 2015, Pages 1426-1434

  Tang, Jinfu ^a   Zhong, Suyu ^a   Chen, Yaojing ^a   Chen, Kewei ^a,b   Zhang, Junying ^a   Gong, Gaolang ^a   Fleisher, Adam S ^b,c   He, Yong ^a   Zhang, Zhanjun ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b BANNER ALZHEIMER S INSTITUTE   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

connectome; diffusion tensor imaging; graph theory; silent lacunar infarcts; white matter network

Indexed keywords

AGED; ARTICLE; BASAL GANGLION; BRAIN REGION; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; DISEASE ASSOCIATION; FEMALE; HUMAN; LACUNAR STROKE; MALE; NERVE CELL NETWORK; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; TRACTOGRAPHY; WHITE MATTER; BRAIN INFARCTION; COGNITION DISORDERS; COMPLICATION; FACTUAL DATABASE; MIDDLE AGED; PATHOLOGY;

AGED; BASAL GANGLIA; BRAIN INFARCTION; COGNITION DISORDERS; DATABASES, FACTUAL; FEMALE; HUMANS; MALE; MIDDLE AGED; WHITE MATTER;

EID: 84940719309     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2015.67     Document Type: Article

References (40)

1. Vermeer SE, Longstreth WT, Koudstaal PJ. Silent brain infarcts: a systematic review. Lancet Neurol 2007; 6: 611-619.
2. Arvanitakis Z, Leurgans SE, Barnes LL, Bennett DA, Schneider JA. Microinfarct pathology, dementia, and cognitive systems. Stroke 2011; 42: 722-727.
3. Heringa SM, Reijmer YD, Leemans A, Koek HL, Kappelle LJ, Biessels GJ. Multiple microbleeds are related to cerebral network disruptions in patients with early Alzheimer's disease. J Alzheimers Dis 2014; 38: 211-221.
4. Reijmer YD, Freeze WM, Leemans A, Biessels GJ. The effect of lacunar infarcts on white matter tract integrity. Stroke 2013; 44: 2019-2021.
5. Reijmer YD, Fotiadis P, Martinez-Ramirez S, Salat DH, Schultz A, Shoamanesh A et al. Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy. Brain 2015; 138: 179-188.
6. Sporns O, Tononi G, Kotter R. The human connectome: a structural description of the human brain. PLoS Comput Biol 2005; 1: e42.
7. Sporns O. Structure and function of complex brain networks. Dialogues Clin Neurosci 2013; 15: 247-262.
8. Wang L, Yu C, Chen H, Qin W, He Y, Fan F et al. Dynamic functional reorganization of the motor execution network after stroke. Brain 2010; 133(Pt 4): 1224-1238.
9. Shu N, Liang Y, Li H, Zhang J, Li X, Wang L et al. Disrupted topological organization in white matter structural networks in amnestic mild cognitive impairment: relationship to subtype. Radiology 2012; 265: 518-527.
10. Yao Z, Zhang Y, Lin L, Zhou Y, Xu C, Jiang T. Abnormal cortical networks in mild cognitive impairment and Alzheimer's disease. PLoS Comput Biol 2010; 6: e1001006.
11. Lo CY, Wang PN, Chou KH, Wang J, He Y, Lin CP. Diffusion tensor tractography reveals abnormal topological organization in structural cortical networks in Alzheimer's disease. J Neurosci 2010; 30: 16876-16885.
12. Supekar K, Menon V, Rubin D, Musen M, Greicius MD. Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. PLoS Comput Biol 2008; 4: e1000100.
13. Reijmer YD, Leemans A, Caeyenberghs K, Heringa SM, Koek HL, Biessels GJ. Disruption of cerebral networks and cognitive impairment in Alzheimer disease. Neurology 2013; 80: 1370-1377.
14. Bellebaum C, Koch B, Schwarz M, Daum I. Focal basal ganglia lesions are associated with impairments in reward-based reversal learning. Brain 2008; 131: 829-841.
15. Mayor-Dubois C, Maeder P, Zesiger P, Roulet-Perez E. Visuo-motor and cognitive procedural learning in children with basal ganglia pathology. Neuropsychologia 2010; 48: 2009-2017.
16. Talati A, Hirsch J. Functional specialization within the medial frontal gyrus for perceptual go/no-go decisions based on "what, " "when, " and "where" related information: an fMRI study. J Cogn Neurosci 2005; 17: 981-993.
17. Wardlaw JM, Smith EE, Biessels GJ, Cordonnier C, Fazekas F, Frayne R et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 2013; 12: 822-838.
18. Fisher CM. Lacunes: Small, deep cerebral infarcts. Neurology 2011; 77: 2104.
19. Wang L, Li H, Liang Y, Zhang J, Li X, Shu N et al. Amnestic mild cognitive impairment: topological reorganization of the default-mode network. Radiology 2013; 268: 501-514.
20. Cui Z, Zhong S, Xu P, He Y, Gong G. PANDA: a pipeline toolbox for analyzing brain diffusion images. Front Hum Neurosci 2013; 7: 42.
21. Leemans A, Jones DK. The B matrix must be rotated when correcting for subject motion in DTI data. Magn Reson Med 2009; 61: 1336-1349.
22. Ashburner J, Friston KJ. Unified segmentation. Neuroimage 2005; 26: 839-851.
23. Mori S, Crain BJ, Chacko V, Van Zijl P. Three dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol 1999; 45: 265-269.
24. Gong G, Rosa-Neto P, Carbonell F, Chen ZJ, He Y, Evans AC. Age-and genderrelated differences in the cortical anatomical network. J Neurosci 2009; 29: 15684-15693.
25. Achard S, Bullmore E. Efficiency and cost of economical brain functional networks. PLoS Comput Biol 2007; 3: e17.
26. Latora V, Marchiori M. Efficient behavior of small-world networks. Phys Rev Lett 2001; 87: 198701.
27. Watts DJ, Strogatz SH. Collective dynamics of 'small-world'networks. Nature 1998; 393: 440-442.
28. Maslov S, Sneppen K. Specificity and stability in topology of protein networks. Science 2002; 296: 910-913.
29. Yan C, Gong G, Wang J, Wang D, Liu D, Zhu C et al. Sex-and brain size-related small-world structural cortical networks in young adults: a DTI tractography study. Cereb Cortex 2011; 21: 449-458.
30. Chen Y, Wang J, Zhang J, Zhang T, Chen K, Fleisher A et al. Aberrant functional networks connectivity and structural atrophy in silent lacunar infarcts: relationship with cognitive impairments. J Alzheimers Dis 2014; 42: 841-850.
31. van Meer MPA, Otte WM, van der Marel K, Nijboer CH, Kavelaars A, van der Sprenkel JWB et al. Extent of bilateral neuronal network reorganization and functional recovery in relation to stroke severity. J Neurosci 2012; 32: 4495-4507.
32. Smith Y, Bevan M, Shink E, Bolam J. Microcircuitry of the direct and indirect pathways of the basal ganglia. Neuroscience 1998; 86: 353.
33. McNab F, Klingberg T. Prefrontal cortex and basal ganglia control access to working memory. Nat Neurosci 2007; 11: 103-107.
34. Denys K, Vanduffel W, Fize D, Nelissen K, Peuskens H, Van Essen D et al. The processing of visual shape in the cerebral cortex of human and nonhuman primates: a functional magnetic resonance imaging study. J Neurosci 2004; 24: 2551-2565.
35. Lee D, Quessy S. Activity in the supplementary motor area related to learning and performance during a sequential visuomotor task. J Neurophysiol 2003; 89: 1039-1056.
36. Saarinen T, Laaksonen H, Parviainen T, Salmelin R. Motor cortex dynamics in visuomotor production of speech and non-speech mouth movements. Cereb Cortex 2006; 16: 212-222.
37. Badre D, Wagner AD. Left ventrolateral prefrontal cortex and the cognitive control of memory. Neuropsychologia 2007; 45: 2883-2901.
38. Epstein R, Kanwisher N. A cortical representation of the local visual environment. Nature 1998; 392: 598-601.
39. Jones DK, Knösche TR, Turner R. White matter integrity, fiber count, and other fallacies: the do's and don'ts of diffusion MRI. Neuroimage 2013; 73: 239-254.
40. Tournier J-D, Mori S, Leemans A. Diffusion tensor imaging and beyond. Magn Reson Med 2011; 65: 1532-1556.