Relation of serum uric acid to cardiovascular disease

International Journal of Cardiology

Volumn 213, Issue , 2016, Pages 4-7

  Wu, Audrey H ^a   Gladden, James D ^b   Ahmed, Mustafa ^c   Ahmed, Ali ^c   Filippatos, Gerasimos ^d  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^d NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

Author keywords

Cardiovascular disease; Review; Uric acid

Indexed keywords

ALLOPURINOL; GLUCOSE; OXIPURINOL; URIC ACID; XANTHINE OXIDASE;

ARTICLE; ATRIAL FIBRILLATION; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CONGESTIVE CARDIOMYOPATHY; CONGESTIVE HEART FAILURE; DISEASE ASSOCIATION; DISEASE SEVERITY; DISORDERS OF CARBOHYDRATE METABOLISM; DYSLIPIDEMIA; ENZYME INHIBITION; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HUMAN; HYPERTENSION; HYPERURICEMIA; ISCHEMIC HEART DISEASE; NONHUMAN; NONISCHEMIC CARDIOMYOPATHY; OBESITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYSTOLIC HEART FAILURE; TREATMENT DURATION; TREATMENT OUTCOME; UPREGULATION; URIC ACID BLOOD LEVEL; BLOOD; CARDIOVASCULAR DISEASES; FEMALE; MALE; METABOLISM; MORTALITY; RISK FACTOR; SEVERITY OF ILLNESS INDEX;

CARDIOVASCULAR DISEASES; FEMALE; HUMANS; MALE; RISK FACTORS; SEVERITY OF ILLNESS INDEX; URIC ACID;

EID: 84940704969     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.08.110     Document Type: Article

References (58)

1. F.N. Brand, D.L. McGee, W.B. Kannel, J. Stokes III, and W.P. Castelli Hyperuricemia as a risk factor of coronary heart disease: the Framingham Study Am. J. Epidemiol. 121 1985 11 18
2. W. Rathmann, E. Funkhouser, A.R. Dyer, and J.M. Roseman Relations of hyperuricemia with the various components of the insulin resistance syndrome in young black and white adults: the CARDIA study. Coronary Artery Risk Development in Young Adults Ann. Epidemiol. 8 1998 250 261
3. J. Fang, and M.H. Alderman Serum uric acid and cardiovascular mortality the NHANES I Epidemiologic Follow-up Study, 1971-1992. National Health and Nutrition Examination Survey JAMA 283 2000 2404 2410
4. L.K. Niskanen, D.E. Laaksonen, K. Nyyssonen, and et al. Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men: a prospective cohort study Arch. Intern. Med. 164 2004 1546 1551
5. B.F. Culleton, M.G. Larson, W.B. Kannel, and D. Levy Serum uric acid and risk for cardiovascular disease and death: the Framingham Heart Study Ann. Intern. Med. 131 1999 7 13
6. A. Dobson Is raised serum uric acid a cause of cardiovascular disease or death? Lancet 354 1999 1578
7. M. Kuzuya, F. Ando, A. Iguchi, and H. Shimokata Effect of aging on serum uric acid levels: longitudinal changes in a large Japanese population group J. Gerontol. A Biol. Sci. Med. Sci. 57 2002 M660 M664
8. S.G. Wannamethee, A.G. Shaper, and P.H. Whincup Serum urate and the risk of major coronary heart disease events Heart 78 1997 147 153
9. A.L. Gaffo, J.M. Roseman, and D.R. Jacobs Jr Serum urate and its relationship with alcoholic beverage intake in men and women: findings from the Coronary Artery Risk Development in Young Adults (CARDIA) cohort Ann. Rheum. Dis. 69 2010 1965 1970
10. H.K. Choi, K. Atkinson, E.W. Karlson, W. Willett, and G. Curhan Purine-rich foods, dairy and protein intake, and the risk of gout in men N. Engl. J. Med. 350 2004 1093 1103
11. I.M. Palmer, A.E. Schutte, and H.W. Huisman Uric acid and the cardiovascular profile of African and Caucasian men J. Hum. Hypertens 24 2010 639 645
12. V.S. Voruganti, S.D. Nath, S.A. Cole, and et al. Genetics of variation in serum uric acid and cardiovascular risk factors in Mexican Americans J. Clin. Endocrinol. Metab. 94 2009 632 638
13. B.A. Charles, D. Shriner, and A. Doumatey A genome-wide association study of serum uric acid in African Americans BMC Med. Genomics 4 2011 17
14. M. Moser, and P.U. Feig Fifty years of thiazide diuretic therapy for hypertension Arch. Intern. Med. 169 2009 1851 1856
15. A. Quinones Galvan, A. Natali, S. Baldi, and et al. Effect of insulin on uric acid excretion in humans Am. J. Physiol. 268 1995 E1 E5
16. H. Sumino, S. Ichikawa, T. Kanda, T. Nakamura, and T. Sakamaki Reduction of serum uric acid by hormone replacement therapy in postmenopausal women with hyperuricaemia Lancet 354 1999 650
17. S. Watanabe, D.H. Kang, L. Feng, and et al. Uric acid, hominoid evolution, and the pathogenesis of salt-sensitivity Hypertension 40 2002 355 360
18. J.M. Hare, and R.J. Johnson Uric acid predicts clinical outcomes in heart failure: insights regarding the role of xanthine oxidase and uric acid in disease pathophysiology Circulation 107 2003 1951 1953
19. J.H. Chen, S.Y. Chuang, H.J. Chen, W.T. Yeh, and W.H. Pan Serum uric acid level as an independent risk factor for all-cause, cardiovascular, and ischemic stroke mortality: a Chinese cohort study Arthritis Rheum. 61 2009 225 232
20. S. Kivity, E. Kopel, E. Maor, and et al. Association of serum uric acid and cardiovascular disease in healthy adults Am. J. Cardiol. 111 2013 1146 1151
21. J.P. Forman, H. Choi, and G.C. Curhan Uric acid and insulin sensitivity and risk of incident hypertension Arch. Intern. Med. 169 2009 155 162
22. L.V. Franse, M. Pahor, M. Di Bari, and et al. Serum uric acid, diuretic treatment and risk of cardiovascular events in the Systolic Hypertension in the Elderly Program (SHEP) J. Hypertens. 18 2000 1149 1154
23. A. Hoieggen, M.H. Alderman, S.E. Kjeldsen, and et al. The impact of serum uric acid on cardiovascular outcomes in the LIFE study Kidney Int. 65 2004 1041 1049
24. T. Hamada, K. Ichida, M. Hosoyamada, and et al. Uricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patients Am. J. Hypertens. 21 2008 1157 1162
25. O.L. Pedersen, F.K. Jacobsen, and K. Stengaard-Pedersen Renal uric acid handling is not affected by beta-adrenoceptor blockade in normotensive subjects Eur. J. Clin. Pharmacol. 28 1985 223 224
26. I. Sihm, K. Thygesen, L.R. Krusell, and O. Lederballe Long-term renal and cardiovascular effects of antihypertensive treatment regimens based upon isradipine, perindopril and thiazide Blood Press. 9 2000 346 354
27. A.J. Reyes Cardiovascular drugs and serum uric acid Cardiovasc. Drugs Ther. 17 2003 397 414
28. A.G. Ioachimescu, D.M. Brennan, B.M. Hoar, S.L. Hazen, and B.J. Hoogwerf Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: a preventive cardiology information system (PreCIS) database cohort study Arthritis Rheum. 58 2008 623 630
29. E. Krishnan, K. Svendsen, J.D. Neaton, G. Grandits, and L.H. Kuller Long-term cardiovascular mortality among middle-aged men with gout Arch. Intern. Med. 168 2008 1104 1110
30. S. Kojima, T. Sakamoto, M. Ishihara, and et al. Prognostic usefulness of serum uric acid after acute myocardial infarction (the Japanese Acute Coronary Syndrome Study) Am. J. Cardiol. 96 2005 489 495
31. T. Killip III, and J.T. Kimball Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients Am. J. Cardiol. 20 1967 457 464
32. G. Ndrepepa, S. Braun, H.U. Haase, and et al. Prognostic value of uric acid in patients with acute coronary syndromes Am. J. Cardiol. 109 2012 1260 1265
33. O.J. Ekundayo, L.J. Dell'Italia, P.W. Sanders, and et al. Association between hyperuricemia and incident heart failure among older adults: a propensity-matched study Int. J. Cardiol. 142 2010 279 287
34. R.V. Desai, M.I. Ahmed, G.C. Fonarow, and et al. Effect of serum insulin on the association between hyperuricemia and incident heart failure Am. J. Cardiol. 106 2010 1134 1138
35. M.M. Kittleson, M.E. St John, V. Bead, and et al. Increased levels of uric acid predict haemodynamic compromise in patients with heart failure independently of B-type natriuretic peptide levels Heart 93 2007 365 367
36. W. Doehner, M. Rauchhaus, V.G. Florea, and et al. Uric acid in cachectic and noncachectic patients with chronic heart failure: relationship to leg vascular resistance Am. Heart J. 141 2001 792 799
37. S.D. Anker, F. Leyva, P.A. Poole-Wilson, W.J. Kox, J.C. Stevenson, and A.J. Coats Relation between serum uric acid and lower limb blood flow in patients with chronic heart failure Heart 78 1997 39 43
38. M. Cicoira, L. Zanolla, A. Rossi, and et al. Elevated serum uric acid levels are associated with diastolic dysfunction in patients with dilated cardiomyopathy Am. Heart J. 143 2002 1107 1111
39. W.C. Levy, D. Mozaffarian, D.T. Linker, and et al. The Seattle Heart Failure Model: prediction of survival in heart failure Circulation 113 2006 1424 1433
40. A.H. Wu, J.K. Ghali, G.W. Neuberg, C.M. O'Connor, P.E. Carson, and W.C. Levy Uric acid level and allopurinol use as risk markers of mortality and morbidity in systolic heart failure Am. Heart. J. 160 2010 928 933
41. S.D. Anker, W. Doehner, M. Rauchhaus, and et al. Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging Circulation 107 2003 1991 1997
42. G.S. Filippatos, M.I. Ahmed, J.D. Gladden, and et al. Hyperuricaemia, chronic kidney disease, and outcomes in heart failure: potential mechanistic insights from epidemiological data Eur. Heart J. 32 2011 712 720
43. L. Tamariz, S. Agarwal, E.Z. Soliman, and et al. Association of serum uric acid with incident atrial fibrillation (from the Atherosclerosis Risk in Communities [ARIC] study) Am. J. Cardiol. 108 2011 1272 1276
44. F. Valbusa, L. Bertolini, S. Bonapace, and et al. Relation of elevated serum uric acid levels to incidence of atrial fibrillation in patients with type 2 diabetes mellitus Am. J. Cardiol. 112 2013 499 504
45. L. Tamariz, F. Hernandez, A. Bush, A. Palacio, and J.M. Hare Association between serum uric acid and atrial fibrillation: a systematic review and meta-analysis Heart Rhythm 11 2014 1102 1108
46. K.P. Letsas, P. Korantzopoulos, G.S. Filippatos, C.C. Mihas, V. Markou, G. Gavrielatos, M. Efremidis, A. Sideris, and F. Kardaras Uric acid elevation in atrial fibrillation Hell. J. Cardiol. 51 2010 209 213
47. G.A. Hirsch, P.A. Bottomley, G. Gerstenblith, and R.G. Weiss Allopurinol acutely increases adenosine triphospate energy delivery in failing human hearts J. Am. Coll. Cardiol. 59 2012 802 808
48. W. Doehner, N. Schoene, M. Rauchhaus, and et al. Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies Circulation 105 2002 2619 2624
49. K. Ogino, M. Kato, and Y. Furuse Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study Circ. Heart Fail. 3 2010 73 81
50. J. George, E. Carr, J. Davies, J.J. Belch, and A. Struthers High-dose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid Circulation 114 2006 2508 2516
51. J.M. Hare, B. Mangal, J. Brown, and et al. Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study J. Am. Coll. Cardiol. 51 2008 2301 2309
52. M.M. Givertz, D.L. Mann, K.L. Lee, and et al. Xanthine oxidase inhibition for hyperuricemic heart failure patients: design and rationale of the EXACT-HF study Circ. Heart Fail. 6 2013 862 868
53. P. Higgins, M.R. Walters, H.M. Murray, and et al. Allopurinol reduces brachial and central blood pressure, and carotid intima-media thickness progression after ischaemic stroke and transient ischaemic attack: a randomised controlled trial Heart 100 2014 1085 1092
54. B.R. Szwejkowski, S.J. Gandy, S. Rekhraj, and et al. Allopurinol reduces left ventricular mass in patients with type 2 diabetes and left ventricular hypertrophy J. Am. Coll. Cardiol. 62 2013 2284 2293
55. S. Rekhraj, S.J. Gandy, B.R. Szwejkowski, and et al. High-dose allopurinol reduces left ventricular mass in patients with ischemic heart disease J. Am. Coll. Cardiol. 61 2013 926 932
56. D. Levy, R.J. Garrison, D.D. Savage, W.B. Kannel, and W.P. Castelli Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study N. Engl. J. Med. 322 1990 1561 1566
57. R.B. Devereux, K. Wachtell, E. Gerdts, and et al. Prognostic significance of left ventricular mass change during treatment of hypertension JAMA 292 2004 2350 2356
58. M. Sakabe, A. Fujiki, T. Sakamoto, Y. Nakatani, K. Mizumaki, and H. Inoue Xanthine oxidase inhibition prevents atrial fibrillation in a canine model of atrial pacing-induced left ventricular dysfunction J. Cardiovasc. Electrophysiol. 23 2012 1130 1135