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Volumn 95, Issue 28, 2015, Pages 2264-2267

PTEN loss correlates with the clinical efficacy of lapatinib in HER2 positive metastatic breast cancer with trastuzumab-resistance

Author keywords

Breast neoplasms; Drug resistance; Epidermal growth factor; Receptor

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; LAPATINIB; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TRASTUZUMAB; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; QUINAZOLINE DERIVATIVE;

EID: 84940670504     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2015.28.005     Document Type: Article
Times cited : (5)

References (12)
  • 1
    • 84883325272 scopus 로고    scopus 로고
    • Personalizing the treatment oi women with early breast cancer; highlights of the Si Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013 [J]
    • Goldhirseh A, WinerEP, Coates AS, et al. Personalizing the treatment oi women with early breast cancer; highlights of the Si Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013 [J]. Ann Oncol, 2013, 24(28 ) : 2206- 2223.
    • (2013) Ann Oncol , vol.24 , Issue.28 , pp. 2206-2223
    • Goldhirseh, A.1    Winer, E.P.2    Coates, A.S.3
  • 2
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuznmah as a single agent in first-line treatment of HER2- overexpressing metastatic breast cancer[J]
    • Vogel CI., Cobleigh MA, Tripatliv D, et al. Efficacy and safety of trastuznmah as a single agent in first-line treatment of HER2- overexpressing metastatic breast cancer[J]. J Clin Oncol, 2002, 20(3) : 719-726.
    • (2002) J Clin Oncol , vol.20 , Issue.3 , pp. 719-726
    • Vogel, C.I.1    Cobleigh, M.A.2    Tripatliv, D.3
  • 3
    • 22344446208 scopus 로고    scopus 로고
    • Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positiye metastatic breast cancer administered as first-line treatment: The M77001 study group[J]
    • Marty M, Cognelti F, Maraninchi D, et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positiye metastatic breast cancer administered as first-line treatment: The M77001 study group[J]. J Clin Oncol, 2005, 23 (19): 4265-4274.
    • (2005) J Clin Oncol , vol.23 , Issue.19 , pp. 4265-4274
    • Marty, M.1    Cognelti, F.2    Maraninchi, D.3
  • 4
    • 0035869407 scopus 로고    scopus 로고
    • Bse of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2[J]
    • Slamon DJ, Leyland-Jones B, Shak S, et al. bse of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2[J], N Engl J Med, 2001, 344 ( 11 ) : 783-792.
    • (2001) N Engl J Med , vol.344 , Issue.11 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 5
    • 33646712747 scopus 로고    scopus 로고
    • Mechanisms of disease; understanding resistance to HER2-targetedtherapy in human breast cancer [J]
    • Nahta R, Yu D, Hung MC, et al. Mechanisms of disease; understanding resistance to HER2-targetedtherapy in human breast cancer [J], Nat Clin Praet Oncol, 2006, 3(5) : 269-280.
    • (2006) Nat Clin Praet Oncol , vol.3 , Issue.5 , pp. 269-280
    • Nahta, R.1    Yu, D.2    Hung, M.C.3
  • 6
    • 33845886440 scopus 로고    scopus 로고
    • Lapatinib plus capecitabine for HER2-positive advanced breast cancer [ J ]
    • Geyer CE, Korster J, Lindquist D, et al. Lapatinib plus capecitabine for HER2-positive advanced breast cancer [ J ] . N Engl J Med, 2006, 355(25) :2733-2743.
    • (2006) N Engl J Med , vol.355 , Issue.25 , pp. 2733-2743
    • Geyer, C.E.1    Korster, J.2    Lindquist, D.3
  • 7
    • 84897561243 scopus 로고    scopus 로고
    • Ki-67 index as a prognostic lactor of subsequent lapatinib-hased therapy in HER2-positive metastatic breast cancer yvith resistance to trastuzumab [ J ]
    • Bian L, Wang T, Jiang ZF, et al. Ki-67 index as a prognostic lactor of subsequent lapatinib-hased therapy in HER2-positive metastatic breast cancer yvith resistance to trastuzumab [ J ] . Cancer Biol Ther, 2014, 15(4) :365-370.
    • (2014) Cancer Biol Ther , vol.15 , Issue.4 , pp. 365-370
    • Bian, L.1    Wang, T.2    Jiang, Z.F.3
  • 8
    • 84885427821 scopus 로고    scopus 로고
    • Trastuzumab plus capecitabine vs. Lapatinib plus capecitabine in patients with trastuzumab resistance and taxane-pretreated metastatic breast cancer [ J ]
    • Bian L, Wang I, Zhang S, el al. Trastuzumab plus capecitabine vs. lapatinib plus capecitabine in patients with trastuzumab resistance and taxane-pretreated metastatic breast cancer [ J ] . Tumour Biol, 2013, 34(5). 3153-3158.
    • (2013) Tumour Biol , vol.34 , Issue.5 , pp. 3153-3158
    • Bian, L.1    Wang, I.2    Zhang, S.3
  • 9
    • 79958765919 scopus 로고    scopus 로고
    • P13K pathway activation results in low efficacy of both trastuzumab and lapatinib [J]
    • Wang L, Zhang Q, Zhang J, et al. P13K pathway activation results in low efficacy of both trastuzumab and lapatinib [J]. BMC Cancer, 2011, 11(4); 248.
    • (2011) BMC Cancer , vol.11 , Issue.4 , pp. 248
    • Wang, L.1    Zhang, Q.2    Zhang, J.3
  • 10
    • 56449111358 scopus 로고    scopus 로고
    • Phosphalidylinositol 3- kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor WP-BEZ235 [ J]
    • Eiehhorn PJ, Gill M, Scaltrili M, et al. Phosphalidylinositol 3- kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor WP-BEZ235 [ J]. Cancer Res, 2008, 68(22) : 9221-9230.
    • (2008) Cancer Res , vol.68 , Issue.22 , pp. 9221-9230
    • Eiehhorn, P.J.1    Gill, M.2    Scaltrili, M.3
  • 11
    • 33847013396 scopus 로고    scopus 로고
    • Lapatinib antitumor activity is not dependent upon phosphatase and tensin homologue deleted on chromosome 10 in ErbB2-overexpressing breast cancers [ J]
    • Xia W. Husain I, Liu L, et al. Lapatinib antitumor activity is not dependent upon phosphatase and tensin homologue deleted on chromosome 10 in ErbB2-overexpressing breast cancers [ J]. Cancer Res, 2007, 67(3); 1170-1175.
    • (2007) Cancer Res , vol.67 , Issue.3 , pp. 1170-1175
    • Xia, W.H.I.1    Liu, L.2
  • 12
    • 79951997890 scopus 로고    scopus 로고
    • Loss ol phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers [ J]
    • Dave B, Migliaccio I, Gutierrez MC, et al. Loss ol phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers [ J]. J Clin Oncol, 2011, 29(2) : 166-173.
    • (2011) J Clin Oncol , vol.29 , Issue.2 , pp. 166-173
    • Dave, B.1    Migliaccio, I.2    Gutierrez, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.