Clinical features of human metapneumovirus genotypes in children with acute lower respiratory tract infection in Changsha, China

Journal of Medical Virology

Volumn 87, Issue 11, 2015, Pages 1839-1845

  Zeng, Sai Zhen ^a,b   Xiao, Ni Guang ^a   Zhong, Li Li ^a   Yu, Tian ^a   Zhang, Bing ^a   Duan, Zhao Jun ^b  

^a People's Hospital of Hunan   (China)

^b National Institute for Viral Disease Control and Prevention   (China)

Author keywords

Acute lower respiratory tract infections; Children; Clinical feature; Genotype; Human metapneumovirus

Indexed keywords

ADENOVIRIDAE; ADOLESCENT; ARTICLE; CHILD; CHINA; CLINICAL FEATURE; CORONAVIRIDAE; COUGHING; DEMOGRAPHY; FEMALE; FEVER; GENE SEQUENCE; GENOTYPE; HOSPITALIZED CHILD; HUMAN; HUMAN BOCAVIRUS; HUMAN METAPNEUMOVIRUS; HUMAN PARAINFLUENZA VIRUS 1; HUMAN PARAINFLUENZA VIRUS 2; HUMAN PARAINFLUENZA VIRUS 3; HUMAN RESPIRATORY SYNCYTIAL VIRUS; HUMAN RHINOVIRUS; INFANT; INFLUENZA A VIRUS; INFLUENZA B VIRUS; LOWER RESPIRATORY TRACT INFECTION; M GENE; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; NASOPHARYNGEAL ASPIRATION; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCREENING; VIRUS DETECTION; VIRUS GENE; WHEEZING; CLASSIFICATION; COINFECTION; DNA SEQUENCE; GENETICS; HOSPITALIZATION; ISOLATION AND PURIFICATION; METAPNEUMOVIRUS; MOLECULAR EPIDEMIOLOGY; PARAMYXOVIRIDAE INFECTIONS; PATHOLOGY; PREVALENCE; RESPIRATORY TRACT INFECTIONS; VIROLOGY;

VIRUS PROTEIN;

CHINA; COINFECTION; FEMALE; GENOTYPE; HOSPITALIZATION; HUMAN BOCAVIRUS; HUMANS; INFANT; INFANT, NEWBORN; MALE; METAPNEUMOVIRUS; MOLECULAR EPIDEMIOLOGY; PARAMYXOVIRIDAE INFECTIONS; PREVALENCE; RESPIRATORY TRACT INFECTIONS; SEQUENCE ANALYSIS, DNA; VIRAL STRUCTURAL PROTEINS;

EID: 84940606015     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.24249     Document Type: Article

References (26)

1. Agapov E, Sumino KC, Gaudreault-Keener M, Storch GA, Holtzman MJ. 2006. Genetic variability of human metapneumovirus infection: Evidence of a shift in viral genotype without a change in illness. J Infect Dis 193:396-403.
2. Apostoli P, Zicari S, Lo Presti A, Ciccozzi M, Ciotti M, Caruso A, Fiorentini S. 2012. Human metapneumovirus-associated hospital admissions over five consecutive epidemic seasons: evidence for alternating circulation of different genotypes. J Med Virol 84:511-516.
3. Bellau-Pujol S, Vabret A, Legrand L, Dina J, Gouarin S, Petitjean-Lecherbonnier J, Pozzetto B, Ginevra C, Freymuth F. 2005. Development of three multiplex RT-PCR assays for the detection of 12 respiratory RNA viruses. J Virol Methods 126:53-63.
4. Bosis S, Esposito S, Osterhaus AD, Tremolati E, Begliatti E, Tagliabue C, Corti F, Principi N, Niesters HG. 2008. Association between high nasopharyngeal viral load and disease severity in children with human metapneumovirus infection. J Clin Virol 42:286-290.
5. Cai XY, Wang Q, Lin GY, Cai ZW, Lin CX, Chen PZ, Zhou XH, Xie JC, Lu XD. 2014. Respiratory virus infections among children in South China.J. Med Virol 86:1249-1255.
6. Edwards KM, Zhu Y, Griffin MR, Weinberg GA, Hall CB, Szilagyi PG, Staat MA, Iwane M, Prill MM, Williams JV. 2013. New Vaccine Surveillance Network. Burden of human metapneumovirus infection in young children. N Engl J Med 368:633-643.
7. Fathima S, Lee BE, May-Hadford J, Mukhi S, Drews SJ. 2012. Use of an innovative web-based laboratory surveillance platform to analyze mixed infections between human metapneumovirus (hMPV) and other respiratory viruses circulating in Alberta (AB), Canada (2009-2012). Viruses 4:2754-2765.
8. Feuillet F, Lina B, Rosa-Calatrava M, Boivin G. 2012. Ten years of human metapneumovirus research. J Clin Virol 53:97-105.
9. Greensill J, McNamara PS, Dove W, Flanagan B, Smyth RL, Hart CA. 2003. Human metapneumovirus in severe respiratory syncytial virus bronchiolitis. Emerg Infect Dis. 9:372-375.
10. Hierholzer JC, Halonen PE, Dahlen PO, Bingham PG, McDonough MM. 1993. Detection of adenovirus in clinical specimens by polymerase chain reaction and liquid-phase hybridization quantitated by time-resolved fluorometry. J Clin Microbiol 31:1886-1891.
11. Huck B, Scharf G, Neumann-Haefelin D, Puppe W, Weigl J, Falcone V. 2006. Novel human metapneumovirus sublineage. Emerg Infect Dis 12:147-150.
12. Kim HR, Cho AR, Lee MK, Yun SW, Kim TH. 2012. Genotype variability and clinical features of human metapneumovirus isolated from korean children, 2007 to 2010. J Mol Diagn 14:61-64.
13. Lu G, Li J, Xie Z, Liu C, Guo L, Vernet G, Shen K, Wang J. 2013. Human metapneumovirus associated with community-acquired pneumonia in children in Beijing. China. J Med Virol 85:138-143.
14. McAdam AJ, Hasenbein ME, Feldman HA, Cole SE, Offermann JT, Riley AM, Lieu TA. 2004. Human metapneumovirus in children tested at a tertiary-care hospital. J Infect Dis 190:20-26.
15. Peiris JS, Tang WH, Chan KH, Khong PL, Guan Y, Lau YL, Chiu SS. 2003. Children with respiratory disease associated with metapneumovirus in Hong Kong. Emerg Infect Dis 9:628-633.
16. Pitoiset C, Darniot M, Huet F, Aho SL, Pothier P, Manoha C. 2010. Human metapneumovirus genotypes and severity of disease in young children (n1/4100) during a 7-year study in dijon hospital, france. J Med Virol 82:1782-1789.
17. Reiche J, Jacobsen S, Neubauer K, Hafemann S, Nitsche A, Milde J, Wolff T, Schweiger B. 2014. Human metapneumovirus: Insights from a ten-year molecular and epidemiological analysis in Germany. PLoS One 9:E88342.
18. van den Hoogen BG, de Jong JC, Groen J, Kuiken T, de Groot R, Fouchier RA, Osterhaus AD. 2001. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med 7:719-724.
19. van den Hoogen BG, van Doornum GJ, Fockens JC, Cornelissen JJ, Beyer WE, de Groot R, Osterhaus AD, Fouchier RA. 2003. Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients. J Infect Dis 188:1571-1577.
20. van den Hoogen BG, Osterhaus DM, Fouchier RA. 2004. Clinical impact and diagnosis of human metapneumovirus infection. Pediatr Infect Dis J 23:S25-S32.
21. Vicente D, Montes M, Cilla G, Perez-Yarza EG, Perez-Trallero E. 2006. Differences in clinical severity between genotype a and genotype b human metapneumovirus infection in children. Clin Infect Dis 42:111-113.
22. Wei HY, Tsao KC, Huang CG, Huang YC, Lin TY. 2013. Clinical features of different genotypes/genogroups of human metapneumovirus in hospitalized children. J Microbiol Immunol Infect 46:352-357.
23. Xiao NG, Zhang B, Xie ZP, Zhou QH, Zhang RF, Zhong LL, Ding XF, Li J, Song JR, Gao HC, Hou YD, Duan ZJ. 2013. Prevalence of human metapneumovirus in children with acute lower respiratory infection in Changsha, China. J Med Virol 85:546-553.
24. Yoko Matsuzaki, Tsutomu Itagaki, Chieko Abiko, Yoko Aoki, Asuka Suto, Katsumi Mizuta. 2008. Clinical impact of human metapneumovirus genotypes and genotype-specific seroprevalence in yamagata, Japan. J Med Virol 80:1084-1089.
25. Zhang C, Du LN, Zhang ZY, Qin X, Yang X, Liu P, Chen X, Zhao Y, Liu EM, Zhao XD. 2012. Detection and genetic diversity of human metapneumovirus in hospitalized children with acute respiratory infections in Southwest China. J Clin Microbiol 50:2714-2719.
26. Zhu RN, Qian Y, Zhao LQ, Deng J, Sun Y, Wang F, Liao B, Li Y, Huang RY. 2011. Characterization of human metapneumovirus from pediatric patients with acute respiratory infections in a 4-year period in Beijing. China. Chin Med J (Engl) 124:1623-1628.