Rose myrtle (Rhodomyrtus tomentosa) extract and its component, piceatannol, enhance the activity of DNA polymerase and suppress the inflammatory response elicited by UVB-induced DNA damage in skin cells

Molecular Medicine Reports

Volumn 12, Issue 4, 2015, Pages 5857-5864

  Shiratake, Sawako ^a   Nakahara, Tatsuo ^a   Iwahashi, Hiroyasu ^a   Onodera, Takefumi ^b   Mizushina, Yoshiyuki ^b,c  

^a Maruzen Pharmaceuticals Co Ltd   (Japan)

^b KOBE GAKUIN UNIVERSITY   (Japan)

^c SHINSHU UNIVERSITY   (Japan)

Author keywords

Anti inflammatory activity; DNA damage; DNA polymerase; Normal human epidermal keratinocytes; Piceatannol; Rose myrtle; Ultraviolet B

Indexed keywords

ANTIINFLAMMATORY AGENT; CELL ENZYME; DNA POLYMERASE; PICEATANNOL; PICEATANNOL 4' O BETRA DEXTRO GLUCOPYRANOSIDE; PLANT EXTRACT; PROSTAGLANDIN E2; PYRIMIDINE DIMER; RHODOMYRTUS TOMENTOSA EXTRACT; SKIN PROTECTIVE AGENT; UNCLASSIFIED DRUG; 3,3',4,5'-TETRAHYDROXYSTILBENE; DNA DIRECTED DNA POLYMERASE; STILBENE DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL DEATH; CELL VIABILITY; COLUMN CHROMATOGRAPHY; CONCENTRATION RESPONSE; DERMATITIS; DNA DAMAGE; DRUG CYTOTOXICITY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KERATINOCYTE; MTT ASSAY; PROTEIN SECRETION; PROTON NUCLEAR MAGNETIC RESONANCE; RADIATION INJURY; SKIN CELL; SKIN DEFECT; ULTRAVIOLET B RADIATION; ADVERSE EFFECTS; APOPTOSIS; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVATION; FRUIT; METABOLISM; RADIATION RESPONSE; ROSE; ULTRAVIOLET RADIATION;

APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DINOPROSTONE; DNA DAMAGE; DNA-DIRECTED DNA POLYMERASE; ENZYME ACTIVATION; FRUIT; HUMANS; KERATINOCYTES; PLANT EXTRACTS; ROSA; STILBENES; ULTRAVIOLET RAYS;

EID: 84940528462     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4156     Document Type: Article

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