A controlled antibiotic release system to prevent orthopedic-implant associated infections: An in vitro study

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 96, Issue , 2015, Pages 264-271

  Gimeno, Marina ^a   Pinczowski, Pedro ^a   Pérez, Marta ^a   Giorello, Antonella ^a   Martínez, Miguel Ángel ^a,b   Santamaría, Jesús ^a,b   Arruebo, Manuel ^a,b   Luján, Lluís ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

Antibiotic; Controlled release; Hollow steel implant; Medical device; Orthopedic surgery; Staphylococcus aureus

Indexed keywords

CEFAZOLIN; LINEZOLID; STAINLESS STEEL; ANTIINFECTIVE AGENT; DELAYED RELEASE FORMULATION; DRUG IMPLANT; POWDER; STEEL;

ARTICLE; BACTERIAL CLEARANCE; BONE PIN; DEVICE INFECTION; DRUG DIFFUSION; DRUG SOLUBILITY; HUMAN; IN VITRO STUDY; INTERNAL FIXATOR; OPEN FRACTURE; OSTEOSYNTHESIS; SUSTAINED DRUG RELEASE; ADMINISTRATION AND DOSAGE; ADVERSE EFFECTS; BONE NAIL; CHEMISTRY; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG EFFECTS; DRUG FORMULATION; DRUG IMPLANT; DRUG RELEASE; GROWTH, DEVELOPMENT AND AGING; KINETICS; MECHANICS; MICROBIOLOGY; PHARMACOLOGY; POWDER; PROSTHESIS-RELATED INFECTIONS; SOLUBILITY; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BONE NAILS; CEFAZOLIN; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG COMPOUNDING; DRUG IMPLANTS; DRUG LIBERATION; KINETICS; MECHANICAL PHENOMENA; POWDERS; PROSTHESIS-RELATED INFECTIONS; SOLUBILITY; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; STEEL;

EID: 84940474190     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.08.007     Document Type: Article

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