New insights in the pathophysiology of ovarian cancer and implications for screening and prevention

American Journal of Obstetrics and Gynecology

Volumn 213, Issue 3, 2015, Pages 262-267

  Nezhat, Farr R ^a   Apostol, Radu ^b   Nezhat, Camran ^c   Pejovic, Tanja ^d  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^c Center for Minimally Invasive and Robotic Surgery   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

endometriosis; fallopian tube; ovarian cancer; prevention; risk reducing bilateral salpingo oophorectomy; salpingectomy; screening

Indexed keywords

CANCER CLASSIFICATION; CANCER PREVENTION; CANCER SCREENING; CANCER SURGERY; CLEAR CELL CARCINOMA; CLINICAL TRIAL (TOPIC); ENDOMETRIOID CARCINOMA; ENDOMETRIOSIS; ENDOMETRIUM CARCINOMA; FEMALE; HUMAN; OVARY CANCER; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SALPINGECTOMY; UTERINE TUBE; ADENOCARCINOMA, CLEAR CELL; CANCER GRADING; CARCINOMA, ENDOMETRIOID; CLASSIFICATION; EARLY DIAGNOSIS; NEOPLASMS, CYSTIC, MUCINOUS, AND SEROUS; OVARIAN DISEASES; OVARIAN NEOPLASMS; OVARIECTOMY; PATHOLOGY; PRECANCEROUS CONDITIONS;

ADENOCARCINOMA, CLEAR CELL; CARCINOMA, ENDOMETRIOID; EARLY DETECTION OF CANCER; ENDOMETRIOSIS; FALLOPIAN TUBES; FEMALE; HUMANS; NEOPLASM GRADING; NEOPLASMS, CYSTIC, MUCINOUS, AND SEROUS; OVARIAN DISEASES; OVARIAN NEOPLASMS; OVARIECTOMY; PRECANCEROUS CONDITIONS; SALPINGECTOMY;

EID: 84940462511     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2015.03.044     Document Type: Review

References (53)

1. R. Siegel, J. Ma, Z. Zou, and A. Jemal Cancer statistics, 2014 CA Cancer J Clin 64 2014 9 29
2. T. Kalir, A. Firpo-Betancourt, and F.R. Nezhat Update on ovarian cancer pathogenesis: history, controversies, emerging issues and future impact Exp Rev Obstet Gynecol 8 2013 1 9
3. W.G. McCluggage Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis Pathology 43 2011 420 432
4. S. Buys, E. Partridge, A. Black, and et al. Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening randomized controlled trial JAMA 305 2011 2295 2303
5. A. Sharma, S. Apostolidou, M. Burnell, and et al. Risk of epithelial ovarian cancer in asymptomatic women with ultrasound-detected ovarian masses: a prospective cohort study within the UK collaborative trial of ovarian cancer screening (UKCTOCS) Ultrasound Obstet Gynecol 40 2012 338 344
6. S. Wang, L. Qiu, J.H. Lang, and et al. Clinical analysis of ovarian epithelial carcinoma with coexisting pelvic endometriosis Am J Obstet Gynecol 208 2013 413
7. L. Deligdisch, F. Penault-Llorca, P. Schlosshauer, A. Altchek, M. Peiretti, and F. Nezhat Stage I ovarian carcinoma: different clinical pathologic patterns Fertil Steril 88 2007 906 910
8. B.K. Erickson, M.G. Conner, and C.N. Landen The role of the fallopian tube in the origin of ovarian cancer Am J Obstet Gynecol 209 2013 409 414
9. J.M. Piek, P.J. van Diest, R.P. Zweemer, and et al. Dysplastic changes in prophylactically removed fallopian tubes of women predisposed to developing ovarian cancer J Pathol 195 2001 451 456
10. C.P. Crum, R. Drapkin, A. Miron, and et al. The distal fallopian tube: a new model for pelvic serous carcinogenesis Curr Opin Obstet Gynecol 109 2008 168 173
11. D.W. Kindelberger, Y. Lee, A. Miron, and et al. Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship Am J Surg Pathol 31 2007 161 169
12. C.G. Przybycin, R.J. Kurman, B.M. Ronnett, I.M. Shih, and R. Vang Are all pelvic (nonuterine) serous carcinomas of tubal origin? Am J Surg Pathol 34 2010 1407 1416
13. A.M. Karst, K. Levanon, and R. Drapkin Modeling high-grade serous ovarian carcinogenesis from the fallopian tube Proc Natl Acad Sci USA 108 2011 7547 7552
14. R.J. Kurman Origin and molecular pathogenesis of ovarian high-grade serous carcinoma Ann Oncol 24 Suppl 10 2013 x16 x21
15. F.R. Nezhat, T. Pejovic, F.M. Reis, and S.W. Guo The link between endometriosis and ovarian cancer: clinical implications Int J Gynecol Cancer 24 2014 623 628
16. R.J. Kurman, and I.M. Shih Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer - shifting the paradigm Hum Pathol 42 2011 918 931
17. F. Nezhat, C. Cohen, J. Rahaman, H. Gretz, P. Cole, and T. Kalir Comparative immunohistochemical studies of bcl-2 and p53 proteins in benign and malignant ovarian endometriotic cysts Cancer 94 2002 2935 2940
18. Cancer Genome Atlas Research Network Integrated genomic analyses of ovarian carcinoma Nature 474 2011 609 615
19. M.E. Sherman, M. Piedmonte, P.L. Mai, and et al. Pathologic findings at risk-reducing salpingo-oophorectomy: primary results from Gynecologic Oncology Group Trial GOG-0199 J Clin Oncol 32 2014 3275 3283
20. J.A. Sampson Endometrial carcinoma of ovary arising in endometrial tissue in that organ Arch Surg 10 1925 1 72
21. C.L. Pearce, C. Templeman, M.A. Rossing, and et al. Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies Lancet Oncol 7 2012 385 394
22. H.S. Kim, T.H. Kim, H.H. Chung, and Y.S. Song Risk and prognosis of ovarian cancer in women with endometriosis: a meta-analysis Br J Cancer 110 2014 1878 1890
23. F. Nezhat, M.S. Datta, V. Hanson, T. Pejovic, C. Nezhat, and C. Nezhat The relationship of endometriosis and ovarian malignancy: a review Fertil Steril 90 2008 1559 1570
24. S.M. Suryawanshi, X. Huang, R. Budiu, and et al. Complement pathway is frequently altered in endometriosis and endometriosis-associated ovarian cancer Clin Cancer Res 20 2014 6163 6174
25. B. Eskenazi, and M.L. Warner Epidemiology of endometriosis Obstet Gynecol Clin North Am 24 1997 235 258
26. R. Sainz de la Cuesta, J.H. Eichhorn, L.W. Rice, A.F. Fuller, N. Nikrui, and B.A. Goff Histologic transformation of benign endometriosis to early epithelial ovarian cancer Gynecol Oncol 7 1996 238 244
27. O. Dzatic-Smiljkovic, M. Vasiljevic, M. Djukic, R. Vugdelic, and J. Vugdelic Frequency of ovarian endometriosis in epithelial ovarian cancer patients Clin Exp Obstet Gynecol 7 2011 394 398
28. Agency for Healthcare Research and Quality Management of adnexal mass. Evidence based report/technology assessment no. 130. AHRQ Publication no. 06-E004 2006 Agency for Healthcare Research and Quality Rockville, MD
29. M.C. Lim, K.C. Chun, S.J. Shin, and et al. Clinical presentation of endometrioid epithelial ovarian cancer with concurrent endometriosis: a multicenter retrospective study Cancer Epidemiol Biomarkers Prev 19 2010 398 404
30. C. Walsh, C. Holschneider, Y. Hoang, K. Tieu, B. Karlan, and I. Cass Coexisting ovarian malignancy in young women with endometrial cancer Obstet Gynecol 106 2005 693 699
31. R.B. Ness Endometriosis and ovarian cancer: thoughts on shared pathophysiology Am J Obstet Gynecol 189 2003 280 294
32. E. Somigliana, P. Vigano, F. Parazzini, S. Stoppelli, E. Giambattista, and P. Vercellini Association between endoemetriosis and cancer: a comprehensive review and a critical analysis of clinical and epidemiological evidence Gynecol Oncol 101 2006 331 341
33. V. Beral, R. Doll, C. Hermon, R. Peto, and G. Reeves Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controls Lancet 371 2008 303 314
34. K.A. Rosenblatt, and D.B. Thomas Reduced risk of ovarian cancer in women with a tubal ligation or hysterectomy. The World Health Organization Collaborative Study of Neoplasia and Steroid Contraceptives Cancer Epidemiol Biomarkers Prev 5 1996 933 935
35. A.A. Tone, S. Salvador, S.J. Finlayson, and et al. The role of the fallopian tube in ovarian cancer Clin Adv Hematol Oncol 10 2012 296 306
36. W. Sieh, S. Salvador, V. McGuire, and et al. Tubal ligation and the risk of ovarian cancer subtypes: a pooled analysis of case control studies Int J Epidemiol 42 2013 579 589
37. M.S. Rice, S.E. Hankinson, and S.S. Tworoger Tubal ligation, hysterectomy, unilateral oophorectomy and risk of ovarian cancer in the Nurses Health Studies Fertil Steril 102 2014 192 198
38. Society of Gynecologic Oncology SGO clinical practice statement: salpingectomy for ovarian cancer prevention 2013 Society of Gynecologic Oncology Chicago, IL
39. J.N. McAlpine, G.E. Hanley, M.M. Woo, and et al. Opportunistic salpingectomy: uptake, risks, and complications of a regional initiative for ovarian cancer prevention. Ovarian Cancer Research Program of British Columbia Am J Obstet Gynecol 210 2014 471.e1 471.e11
40. A.N. Morse, C.B. Schroeder, J.F. Magrina, and et al. The risk of hydrosalpinx formation and adnexectomy following tubal ligation and subsequent hysterectomy: a historical cohort study Am J Obstet Gynecol 194 2006 1273 1276
41. H.B. Peterson, Z. Xia, J.M. Hughes, and et al. The risk of pregnancy after tubal sterilization: findings from the US Collaborative Review of Sterilization Am J Obstet Gynecol 174 1996 1161 1168
42. J. Trussell Contraceptive failure in the United States Contraception 70 2004 89 96
43. G.L. Hsieh, K. Antony, R. Masand, and M. Anderson A prospective feasibility study of postpartum distal salpingectomy Obstet Gynecol 123 Suppl 1 2014 92S
44. A.D. Findley, M.T. Siedhoff, K.A. Hobbs, and et al. Short-term effects of salpingectomy during laparoscopic hysterectomy on ovarian reserve: a pilot randomized controlled trial Fertil Steril 100 2013 1704 1708
45. M. Morelli, R. Venturella, R. Mocciaro, and et al. Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: primum non nocere Gynecol Oncol 129 2013 448 451
46. J.E. Schmidt, S.D. Hillis, P.A. Marchbanks, G. Jeng, and H.B. Peterson Requesting information about and obtaining reversal after tubal sterilization: findings from the US Collaborative Review of Sterilization Fertil Steril 74 2000 892 898
47. Y.O. Tanaka, T. Yoshizako, M. Nishida, M. Yamaguchi, K. Sugimura, and Y. Itai Ovarian carcinoma in patients with endometriosis: MR imaging findings AJR Am J Roentgenol 175 2000 1423 1430
48. M. Takeuchi, K. Matsuzaki, H. Uehara, and H. Nishitani Malignant transformation of pelvic endometriosis: MR imaging findings and pathologic correlation Radiographics 26 2006 407 417
49. F. Nezhat, C. Nezhat, C.J. Allan, D.A. Metzger, and D.L. Sears Clinical and histologic classification of endometriomas. Implications for a mechanism of pathogenesis J Reprod Med 37 1992 771 776
50. C. Nezhat, F.R. Nezhat, C.H. Nezhat, and D. Admon Treatment of ovarian endometriosis C.R. Nezhat, Endometriosis: advanced management and surgical techniques 1995 Springer-Verlag New York, NY
51. K. Koga, Y. Osuga, Takemura, M. Takemura, and Y. Taketani Recurrence of endometrioma after laparascopic excision and its prevention by medical management Front Biosci 5 2013 676 683
52. P. Vercellini, S. De Matteis, E. Somigliana, L. Buggio, M.P. Frattaruilo, and L. Fedele Long-term adjuvant therapy for the prevention of postoperative endometrioma recurrence: a systematic review and meta-analysis Acta Obstet Gynecol Scand 92 2013 8 16
53. A.S. Melin, C. Lundholm, N. Malki, M.L. Swahn, P. Sparèn, and A. Bergqvist Hormonal and surgical treatments for endometriosis and risk of epithelial ovarian cancer Acta Obstet Gynecol Scand 92 2013 546 554