메뉴 건너뛰기




Volumn 36, Issue 8, 2015, Pages 5943-5951

CEA serum level as early predictive marker of outcome during EGFR-TKI therapy in advanced NSCLC patients

Author keywords

Carcinoembryonic antigen; Early predictive marker; Epidermal growth factor receptor; Non small cell lung cancer

Indexed keywords

BIOLOGICAL MARKER; CARCINOEMBRYONIC ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; CARCINOEMBRYONIC ANTIGEN BINDING PROTEIN, HUMAN; CELL SURFACE RECEPTOR; EGFR PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR;

EID: 84940436258     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3269-6     Document Type: Article
Times cited : (24)

References (28)
  • 1
    • 22044445517 scopus 로고    scopus 로고
    • National cancer institute of Canada clinical trials group. Erlotinib in previously treated non-small-cell lung cancer
    • COI: 1:CAS:528:DC%2BD2MXmtFaksbo%3D, PID: 16014882
    • Shepherd FA, Rodriguez Pereira J, Ciuleanu T, Tan EH, Hirsh V, Thongprasert S, et al. National cancer institute of Canada clinical trials group. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med. 2005;353:123–32.
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Shepherd, F.A.1    Rodriguez Pereira, J.2    Ciuleanu, T.3    Tan, E.H.4    Hirsh, V.5    Thongprasert, S.6
  • 2
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • COI: 1:CAS:528:DC%2BD1MXhtVygsbfK, PID: 19692680
    • Mok TS, Wu Y-L, Thongprasert S, Yang CH, Chu DT, Saijo N, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009;361(10):947–57.
    • (2009) N Engl J Med , vol.361 , Issue.10 , pp. 947-957
    • Mok, T.S.1    Wu, Y.-L.2    Thongprasert, S.3    Yang, C.H.4    Chu, D.T.5    Saijo, N.6
  • 3
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
    • COI: 1:CAS:528:DC%2BC38XjsVCgsbk%3D, PID: 22285168
    • Rosell R, Carcereny E, Gervais R, Vergnenegre A, Massuti B, Felip E, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol. 2012;13:239–46.
    • (2012) Lancet Oncol , vol.13 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3    Vergnenegre, A.4    Massuti, B.5    Felip, E.6
  • 4
    • 22044453790 scopus 로고    scopus 로고
    • Erlotinib in lung cancer—molecular and clinical predictors of outcome
    • COI: 1:CAS:528:DC%2BD2MXmtFejt70%3D, PID: 16014883
    • Tsao MS, Sakurada A, Cutz JC, Zhu CQ, Kamel-Reid S, Squire J, et al. Erlotinib in lung cancer—molecular and clinical predictors of outcome. N Engl J Med. 2005;353:133–44.
    • (2005) N Engl J Med , vol.353 , pp. 133-144
    • Tsao, M.S.1    Sakurada, A.2    Cutz, J.C.3    Zhu, C.Q.4    Kamel-Reid, S.5    Squire, J.6
  • 5
    • 77953541527 scopus 로고    scopus 로고
    • Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled, phase III study
    • COI: 1:CAS:528:DC%2BC3cXntVCksb0%3D, PID: 20493771
    • Cappuzzo F, Ciuleanu T, Stelmakh L, Cicenas S, Szczésna A, Juhász E, et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled, phase III study. Lancet Oncol. 2010;11:521–9.
    • (2010) Lancet Oncol , vol.11 , pp. 521-529
    • Cappuzzo, F.1    Ciuleanu, T.2    Stelmakh, L.3    Cicenas, S.4    Szczésna, A.5    Juhász, E.6
  • 6
    • 0027511899 scopus 로고
    • Prostate-specific antigen as a measure of disease outcome in hormone-refractory prostatic cancer
    • COI: 1:STN:280:DyaK3s3ktVWrsA%3D%3D, PID: 7683043
    • Kelly WK, Scher HI, Mazumdar M, Vlamis V, Schwartz M, Fossa SD. Prostate-specific antigen as a measure of disease outcome in hormone-refractory prostatic cancer. J Clin Oncol. 1993;11:607–15.
    • (1993) J Clin Oncol , vol.11 , pp. 607-615
    • Kelly, W.K.1    Scher, H.I.2    Mazumdar, M.3    Vlamis, V.4    Schwartz, M.5    Fossa, S.D.6
  • 7
    • 0032978688 scopus 로고    scopus 로고
    • Comparison of standard and CA-125 response criteria in patients with epithelial ovarian cancer treated with platinum or paclitaxel
    • COI: 1:CAS:528:DyaK1MXht1Wmur0%3D, PID: 10080591
    • Bridgewater JA, Nelstrop AE, Rustin GJ, Gore ME, McGuire WP, Hoskins WJ. Comparison of standard and CA-125 response criteria in patients with epithelial ovarian cancer treated with platinum or paclitaxel. J Clin Oncol. 1999;17:501–8.
    • (1999) J Clin Oncol , vol.17 , pp. 501-508
    • Bridgewater, J.A.1    Nelstrop, A.E.2    Rustin, G.J.3    Gore, M.E.4    McGuire, W.P.5    Hoskins, W.J.6
  • 8
    • 84859435256 scopus 로고    scopus 로고
    • Carcinoembryonic antigen (CEA) as tumor marker in lung cancer
    • COI: 1:STN:280:DC%2BC38zosFykug%3D%3D, PID: 22153832
    • Grunnet M, Sorensen JB. Carcinoembryonic antigen (CEA) as tumor marker in lung cancer. Lung Cancer. 2012;76:138–43.
    • (2012) Lung Cancer , vol.76 , pp. 138-143
    • Grunnet, M.1    Sorensen, J.B.2
  • 9
    • 0032811633 scopus 로고    scopus 로고
    • CYFRA 21–1 in the early diagnosis of recurrent disease in non-small-cell lung carcinomas (NSCLC)
    • Stieber P, Zimmermann A, Reinmiedl J, Muller C, Hoffmann H, Dienemann H. CYFRA 21–1 in the early diagnosis of recurrent disease in non-small-cell lung carcinomas (NSCLC). Anticancer Res. 1999;19:665–8.
    • (1999) Anticancer Res , vol.19 , pp. 665-668
    • Stieber, P.1    Zimmermann, A.2    Reinmiedl, J.3    Muller, C.4    Hoffmann, H.5    Dienemann, H.6
  • 10
    • 3042710800 scopus 로고    scopus 로고
    • CYFRA 21–1 is a prognostic determinant in non-small-cell lung cancer: results of a meta-analysis in 2063 patients
    • PID: 15150567
    • Pujol JL, Molinier O, Ebert W, Daurès JP, Barlesi F, Buccheri G, et al. CYFRA 21–1 is a prognostic determinant in non-small-cell lung cancer: results of a meta-analysis in 2063 patients. Br J Cancer. 2004;90:2097–105.
    • (2004) Br J Cancer , vol.90 , pp. 2097-2105
    • Pujol, J.L.1    Molinier, O.2    Ebert, W.3    Daurès, J.P.4    Barlesi, F.5    Buccheri, G.6
  • 11
    • 0038666373 scopus 로고    scopus 로고
    • Serum CYFRA 21–1 in advanced stage non-small cell lung cancer: an early measure of response
    • COI: 1:CAS:528:DC%2BD3sXjsFeit74%3D, PID: 12738727
    • Vollmer RT, Govindan R, Graziano SL, Gamble G, Garst J, Kelley MJ, et al. Serum CYFRA 21–1 in advanced stage non-small cell lung cancer: an early measure of response. Clin Cancer Res. 2003;9:1728–33.
    • (2003) Clin Cancer Res , vol.9 , pp. 1728-1733
    • Vollmer, R.T.1    Govindan, R.2    Graziano, S.L.3    Gamble, G.4    Garst, J.5    Kelley, M.J.6
  • 12
    • 57649091090 scopus 로고    scopus 로고
    • Nucleosomes and CYFRA 21–1 indicate tumor response after one cycle of chemotherapy in recurrent non-small cell lung cancer
    • PID: 18571761
    • Holdenrieder S, Von Pawel J, Dankelmann E, Duell T, Faderl B, Markus A, et al. Nucleosomes and CYFRA 21–1 indicate tumor response after one cycle of chemotherapy in recurrent non-small cell lung cancer. Lung Cancer. 2008;63:128–35.
    • (2008) Lung Cancer , vol.63 , pp. 128-135
    • Holdenrieder, S.1    Von Pawel, J.2    Dankelmann, E.3    Duell, T.4    Faderl, B.5    Markus, A.6
  • 13
    • 33845570605 scopus 로고    scopus 로고
    • Decline in serum carcinoembryonic antigen and cytokeratin 19 fragment during chemotherapy predicts objective response and survival in advanced non-small-cell lung cancer
    • COI: 1:CAS:528:DC%2BD2sXovF2isg%3D%3D, PID: 17103443
    • Ardizzoni A, Cafferata MA, Tiseo M, Filiberti R, Marroni P, Grossi F, et al. Decline in serum carcinoembryonic antigen and cytokeratin 19 fragment during chemotherapy predicts objective response and survival in advanced non-small-cell lung cancer. Cancer. 2006;107:2842–9.
    • (2006) Cancer , vol.107 , pp. 2842-2849
    • Ardizzoni, A.1    Cafferata, M.A.2    Tiseo, M.3    Filiberti, R.4    Marroni, P.5    Grossi, F.6
  • 14
    • 75749153247 scopus 로고    scopus 로고
    • Predictors of gefitinib outcomes in advanced non-small cell lung cancer (NSCLC): study of a comprehensive panel of molecular markers
    • PID: 19473722
    • Tiseo M, Rossi G, Capelletti M, Sartori G, Spiritelli E, Marchioni A, et al. Predictors of gefitinib outcomes in advanced non-small cell lung cancer (NSCLC): study of a comprehensive panel of molecular markers. Lung Cancer. 2010;67:355–60.
    • (2010) Lung Cancer , vol.67 , pp. 355-360
    • Tiseo, M.1    Rossi, G.2    Capelletti, M.3    Sartori, G.4    Spiritelli, E.5    Marchioni, A.6
  • 16
    • 34447268726 scopus 로고    scopus 로고
    • Serum tumor markers as predictors for survival in advanced non-small cell lung cancer patients treated with gefitinib
    • PID: 17449138
    • Chiu CH, Shih YN, Tsai CM, Liou JL, Chen YM, Perng RP. Serum tumor markers as predictors for survival in advanced non-small cell lung cancer patients treated with gefitinib. Lung Cancer. 2007;57:213–21.
    • (2007) Lung Cancer , vol.57 , pp. 213-221
    • Chiu, C.H.1    Shih, Y.N.2    Tsai, C.M.3    Liou, J.L.4    Chen, Y.M.5    Perng, R.P.6
  • 17
    • 84902975445 scopus 로고    scopus 로고
    • Monitoring of carcinoembryonic antigen levels is predictive of EGFR mutations and efficacy of EGFR-TKI in patients with lung adenocarcinoma
    • COI: 1:CAS:528:DC%2BC2cXntlOktL0%3D
    • Zhang Y, Jin B, Shao M, Dong Y, Lou Y, Huang A, et al. Monitoring of carcinoembryonic antigen levels is predictive of EGFR mutations and efficacy of EGFR-TKI in patients with lung adenocarcinoma. Tumor Biol. 2014;35:4921–8.
    • (2014) Tumor Biol , vol.35 , pp. 4921-4928
    • Zhang, Y.1    Jin, B.2    Shao, M.3    Dong, Y.4    Lou, Y.5    Huang, A.6
  • 18
    • 13244251062 scopus 로고    scopus 로고
    • CYFRA 21–1 level predicts survival in non-small-cell lung cancer patients receiving gefitinib as third-line therapy
    • PID: 15597098
    • Barlési F, Tchouhadjian C, Doddoli C, Torre JP, Astoul P, Kleisbauer JP. CYFRA 21–1 level predicts survival in non-small-cell lung cancer patients receiving gefitinib as third-line therapy. Br J Cancer. 2005;92:13–4.
    • (2005) Br J Cancer , vol.92 , pp. 13-14
    • Barlési, F.1    Tchouhadjian, C.2    Doddoli, C.3    Torre, J.P.4    Astoul, P.5    Kleisbauer, J.P.6
  • 19
    • 20444489613 scopus 로고    scopus 로고
    • Serum carcinoembryonic antigen as a predictive marker for sensitivity to gefitinib in advanced non-small cell lung cancer
    • COI: 1:CAS:528:DC%2BD2MXltFCktrY%3D, PID: 15939264
    • Okamoto T, Nakamura T, Ikeda J, Maruyama R, Shoji F, Miyake T, et al. Serum carcinoembryonic antigen as a predictive marker for sensitivity to gefitinib in advanced non-small cell lung cancer. Eur J Cancer. 2005;41:1286–90.
    • (2005) Eur J Cancer , vol.41 , pp. 1286-1290
    • Okamoto, T.1    Nakamura, T.2    Ikeda, J.3    Maruyama, R.4    Shoji, F.5    Miyake, T.6
  • 20
    • 37048998597 scopus 로고    scopus 로고
    • Serum carcinoembryonic antigen level is associated with epidermal growth factor receptor mutations in recurrent lung adenocarcinomas
    • COI: 1:CAS:528:DC%2BD1cXitVOntw%3D%3D, PID: 17941001
    • Shoji F, Yoshino I, Yano T, Kometani T, Ohba T, Kouso H, et al. Serum carcinoembryonic antigen level is associated with epidermal growth factor receptor mutations in recurrent lung adenocarcinomas. Cancer. 2007;110:2793–8.
    • (2007) Cancer , vol.110 , pp. 2793-2798
    • Shoji, F.1    Yoshino, I.2    Yano, T.3    Kometani, T.4    Ohba, T.5    Kouso, H.6
  • 21
    • 80054743518 scopus 로고    scopus 로고
    • Soluble epidermal growth factor receptor (sEGFR) and carcinoembryonic antigen (CEA) concentration in patients with non-small cell lung cancer: correlation with survival after erlotinib and gefitinib treatment
    • COI: 1:STN:280:DC%2BC387otFOnug%3D%3D, PID: 22276032
    • Kappers I, Vollebergh MA, Van Tinteren H, Korse CM, Nieuwenhuis LL, Bonfrer JM, et al. Soluble epidermal growth factor receptor (sEGFR) and carcinoembryonic antigen (CEA) concentration in patients with non-small cell lung cancer: correlation with survival after erlotinib and gefitinib treatment. Ecancermedicalscience. 2010;4:178.
    • (2010) Ecancermedicalscience , vol.4 , pp. 178
    • Kappers, I.1    Vollebergh, M.A.2    Van Tinteren, H.3    Korse, C.M.4    Nieuwenhuis, L.L.5    Bonfrer, J.M.6
  • 22
    • 79958038844 scopus 로고    scopus 로고
    • Prognostic and predictive value of CEA and CYFRA 21–1 levels in advanced non-small cell lung cancer patients treated with gefitinib or erlotinib
    • COI: 1:CAS:528:DC%2BC3MXos1Kgtbg%3D, PID: 22977560
    • Jung M, Kim SH, Lee YJ, Hong S, Kang YA, Kim SK, et al. Prognostic and predictive value of CEA and CYFRA 21–1 levels in advanced non-small cell lung cancer patients treated with gefitinib or erlotinib. Exp Ther Med. 2011;2:685–93.
    • (2011) Exp Ther Med , vol.2 , pp. 685-693
    • Jung, M.1    Kim, S.H.2    Lee, Y.J.3    Hong, S.4    Kang, Y.A.5    Kim, S.K.6
  • 23
    • 84880923904 scopus 로고    scopus 로고
    • Cytokeratin 19 fragment predicts the efficacy of epidermal growth factor receptor-tyrosine kinase inhibitor in non-small-cell lung cancer harboring EGFR mutation
    • COI: 1:CAS:528:DC%2BC3sXpvV2qtLs%3D, PID: 23591159
    • Tanaka K, Hata A, Kaji R, Fujita S, Otoshi T, Fujimoto D, et al. Cytokeratin 19 fragment predicts the efficacy of epidermal growth factor receptor-tyrosine kinase inhibitor in non-small-cell lung cancer harboring EGFR mutation. J Thorac Oncol. 2013;8:892–8.
    • (2013) J Thorac Oncol , vol.8 , pp. 892-898
    • Tanaka, K.1    Hata, A.2    Kaji, R.3    Fujita, S.4    Otoshi, T.5    Fujimoto, D.6
  • 24
    • 84906308995 scopus 로고    scopus 로고
    • Predictive role of CEA and CYFRA 21–1 in patients with advanced-stage NSCLC treated with erlotinib
    • COI: 1:CAS:528:DC%2BC2cXhtFGrtrjN, PID: 24922695
    • Fiala O, Pesek M, Finek J, Benesova L, Minarik M, Bortlicek Z, et al. Predictive role of CEA and CYFRA 21–1 in patients with advanced-stage NSCLC treated with erlotinib. Anticancer Res. 2014;34:3205–10.
    • (2014) Anticancer Res , vol.34 , pp. 3205-3210
    • Fiala, O.1    Pesek, M.2    Finek, J.3    Benesova, L.4    Minarik, M.5    Bortlicek, Z.6
  • 25
    • 0036204655 scopus 로고    scopus 로고
    • Inhibition of endogenous carcinoembryonic antigen (CEA) increases the apoptotic rate of colon cancer cells and inhibits metastatic tumor growth
    • PID: 11964079
    • Wirth T, Soeth E, Czubayko F, Juhl H. Inhibition of endogenous carcinoembryonic antigen (CEA) increases the apoptotic rate of colon cancer cells and inhibits metastatic tumor growth. Clin Exp Metastasis. 2002;19:155–60.
    • (2002) Clin Exp Metastasis , vol.19 , pp. 155-160
    • Wirth, T.1    Soeth, E.2    Czubayko, F.3    Juhl, H.4
  • 26
    • 0034234257 scopus 로고    scopus 로고
    • Human carcinoembryonic antigen functions as a general inhibitor of anoikis
    • COI: 1:CAS:528:DC%2BD3cXkvFChs78%3D, PID: 10910050
    • Ordonez C, Screaton RA, Ilantzis C, Stanners CP. Human carcinoembryonic antigen functions as a general inhibitor of anoikis. Cancer Res. 2000;60:3419–24.
    • (2000) Cancer Res , vol.60 , pp. 3419-3424
    • Ordonez, C.1    Screaton, R.A.2    Ilantzis, C.3    Stanners, C.P.4
  • 27
    • 79955601409 scopus 로고    scopus 로고
    • Early prediction of nonprogression in advanced non–small-cell lung cancer treated with erlotinib by using [18F] Fluorodeoxyglucose and [18F]fluorothymidine positron emission tomography
    • COI: 1:CAS:528:DC%2BC3MXnslCjt74%3D, PID: 21422426
    • Zander T, Scheffler M, Nogova L, Kobe C, Engel-Riedel W, Hellmich M, et al. Early prediction of nonprogression in advanced non–small-cell lung cancer treated with erlotinib by using [18F] Fluorodeoxyglucose and [18F]fluorothymidine positron emission tomography. J Clin Oncol. 2011;29:1701–8.
    • (2011) J Clin Oncol , vol.29 , pp. 1701-1708
    • Zander, T.1    Scheffler, M.2    Nogova, L.3    Kobe, C.4    Engel-Riedel, W.5    Hellmich, M.6
  • 28
    • 84896033502 scopus 로고    scopus 로고
    • Predictive and prognostic value of early response assessment using 18FDG-PET in advanced non-small cell lung cancer patients treated with erlotinib
    • COI: 1:CAS:528:DC%2BC3sXhvValtrzL, PID: 24258456
    • Tiseo M, Ippolito M, Scarlattei M, Spadaro P, Cosentino S, Latteri F, et al. Predictive and prognostic value of early response assessment using 18FDG-PET in advanced non-small cell lung cancer patients treated with erlotinib. Cancer Chemother Pharmacol. 2014;73:299–307.
    • (2014) Cancer Chemother Pharmacol , vol.73 , pp. 299-307
    • Tiseo, M.1    Ippolito, M.2    Scarlattei, M.3    Spadaro, P.4    Cosentino, S.5    Latteri, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.