A predictive model for blastocyst formation based on morphokinetic parameters in time-lapse monitoring of embryo development

Journal of Assisted Reproduction and Genetics

Volumn 32, Issue 4, 2015, Pages 571-579

  Milewski, Robert ^a   Kuć, Paweł ^a,b   Kuczyńska, Agnieszka ^a,b   Stankiewicz, Bożena ^b   Łukaszuk, Krzysztof ^c,d,e   Kuczyński, Waldemar ^a,b  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^b Centre for Reproductive Medicine KRIOBANK   (Poland)

^c INVICTA Fertility and Reproductive Center   (Poland)

^d MEDICAL UNIVERSITY OF GDANSK   (Poland)

^e University of Varmia and Masuria   (Poland)

Author keywords

Embryoscope; Infertility; IVF ET; Morphokinetic parameters; Time laps recordings

Indexed keywords

ADULT; BIOLOGICAL MODEL; BLASTOCYST; CYTOLOGY; EMBRYO DEVELOPMENT; FEMALE; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; PHYSIOLOGY; PROCEDURES; RETROSPECTIVE STUDY; TIME LAPSE IMAGING;

ADULT; BLASTOCYST; EMBRYONIC DEVELOPMENT; FEMALE; HUMANS; MODELS, BIOLOGICAL; RETROSPECTIVE STUDIES; SPERM INJECTIONS, INTRACYTOPLASMIC; TIME-LAPSE IMAGING;

EID: 84940363631     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-015-0440-3     Document Type: Article

References (16)

1. Milewski R, Milewska AJ, Czerniecki J, Leśniewska M, Wołczyński S. Analysis of the demographic profile of patients treated for infertility using assisted reproductive techniques in 2005–2010. Ginekol Pol. 2013;84(7):609–14.
2. Ebner T, Yaman C, Moser M, Sommergruber M, Feichtinger O, Tews G. Prognostic value of first polar body morphology on fertilization rate and embryo quality in intracytoplasmic sperm injection. Hum Reprod. 2000;15(2):427–30.
3. Scott LA, Smith S. The successful use of pronuclear embryo transfers the day following oocyte retrieval. Hum Reprod. 1998;13(4):1003–13.
4. Kuć P, Kuczyńska A, Stankiewicz B, Sieczyński P, Matysiak J, Kuczyński W. Vitrification vs. slow cooling protocol using embryos cryopreserved in the 5th or 6th day after oocyte retrieval and IVF outcomes. Folia Histochem Cytobiol. 2010;48(1):84–8.
5. Cruz M, Muñoz M, Meseguer M. Real-time imaging strategies to improve morphological assessment. In: Gardner DK, Sakkas D, Seli E, Wells D, editors. Human gametes and Preimplantation embryos. New York: Springer; 2013. p. 45–53.
6. Meseguer M, Herrero J, Tejera A, Hilligsøe KM, Ramsing NB, Remohi J. The use of morphokinetics as a predictor of embryo implantation. Hum Reprod. 2011;26(10):2658–71.
7. Basile N, Meseguer M. Time-lapse technology: evaluation of embryo quality and new markers for embryo selection. Exp Rev Obstet Gynecol. 2012;7(2):175–90.
8. Meseguer M, Rubio I, Cruz M, Basile N, Marcos J, Requena A. Embryo incubation and selection in a time-lapse monitoring system improves pregnancy outcome compared with a standard incubator: a retrospective cohort study. Fertil Steril. 2012;98(6):1481–9.
9. Wong CC, Loewke KE, Bossert NL, et al. Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Nat Biotechnol. 2010;28(10):1115–21.
10. Montag M, Liebenthron J, Köster M. Which morphological scoring system is relevant in human embryo development? Placenta. 2011;32:S252–6.
11. Lemmen JG, Agerholm I, Ziebe S. Kinetic markers of human embryo quality using time-lapse recordings of IVF/ICSI-fertilized oocytes. Reprod Biomed Online. 2008;17(3):385–91.
12. Kirkegaard K, Agerholm IE, Ingerslev HJ. Time-lapse monitoring as a tool for clinical embryo assessment. Hum Reprod. 2012;27(5):1277–85.
13. Cruz M, Gadea B, Garrido N, et al. Embryo quality, blastocyst and ongoing pregnancy rates in oocyte donation patients whose embryos were monitored by time-lapse imaging. J Assist Reprod Genet. 2011;28(7):569–73.
14. Herrero J, Meseguer M. Selection of high potential embryos using time-lapse imaging: the era of morphokinetics. Fertil Steril. 2013;99(4):1030–4.
15. Diamond MP, Willman S, Chenette P, Cedars MI. The clinical need for a method of identification of embryos destined to become a blastocyst in assisted reproductive technology cycles. J Assist Reprod Genet. 2012;29(5):391–6.
16. Cruz M, Garrido N, Herrero J, Pérez-Cano I, Muñoz M, Meseguer M. Timing of cell division in human cleavage-stage embryos is linked with blastocyst formation and quality. Reprod Biomed Online. 2012;25(4):371–81.