Human epididymis protein 4 in early diagnosis of endometrial cancer: A systematic review

Chinese Journal of Evidence-Based Medicine

Volumn 14, Issue 1, 2014, Pages 72-78

  Zhang, Jing ^a   Wang, Yu Juan ^a   Huo, Jun Ling ^a   Wang, Zan Hong ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

Diagnostic test; Endometrial cancer; Human epididymis protein 4; Meta analysis; Systematic review; Tumor marker

Indexed keywords

HUMAN EPIDIDYMIS PROTEIN 4;

DATA BASE; ENDOMETRIUM CANCER; FEMALE; HUMAN; MAJOR CLINICAL STUDY; META ANALYSIS; REVIEW; SYSTEMATIC REVIEW; UTERINE BODY DISEASE;

EID: 84940355758     PISSN: 16722531     EISSN: None     Source Type: Journal    
DOI: 10.7507/1672-2531.20140013     Document Type: Review

References (10)

1. Drapkin R, von Horsten HH, Lin Y, et al. Human epididymis protein 4HE4is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer Res, 2005, 65(6): 2162-2169.
2. Whiting P, Rutjes AW, Reitsma JB, et al. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol, 2003, 3: 25.
3. Moore RG, Brown AK, Miller MC, et al. Utility of a novel serum tumor biomarker HE4 in patients with endometrioid adenocarcinoma of the uterus. Gynecol Oncol, 2008, 110(2): 196-201.
4. Bignotti E, Ragnoli M, Zanotti L, et al. Diagnostic and prognostic impact of serum HE4 detection in endometrial carcinoma patients. Br J Cancer, 2011, 104(9): 1418-1425.
5. Angioli R, Plotti F, Capriglione S, et al. The role of novel biomarker HE4 in endometrial cancer:a case control prospective study. Tumor Biol, 2013, 34: 571-576.
6. Kirchhoff C, Habben I, Ivell R, et al. A major human epididymisspecific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors. Biol Reprod, 1991, 45(2): 350-357.
7. Bingle L, Singleton V, Bingle CD. The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms. Oncogene, 2002, 21(17): 2768-2773.
8. Hellström I, Raycraft J, Hayden-Ledbetter M, et al. The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. Cancer Res, 2003, 63(13): 3695-3700.
9. Montagnana M, Lippi G, Ruzzenente O, et al. The utility of serum human epididymis protein 4 (HE4) in patients with a pelvic mass. J Clin Lab Anal, 2009, 23(5): 331-335.
10. Galgano MT, Hampton GM, Frierson HF Jr. Comprehensive analysis of HE4 expression in normal and malignant human tissues. Mod Pathol, 2006, 19(6): 847-853.