Anti-endothelin receptor type A autoantibodies in systemic lupus erythematosus-associated pulmonary arterial hypertension

Arthritis and Rheumatology

Volumn 67, Issue 9, 2015, Pages 2394-2402

  Guo, Li ^a   Li, Mengtao ^b   Chen, Yi ^a   Wang, Qian ^b   Tian, Zhuang ^b   Pan, Shuming ^a   Zeng, Xiaofeng ^b   Ye, Shuang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN RECEPTOR TYPE A ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; AUTOANTIBODY; ENDOTHELIN A RECEPTOR; MESSENGER RNA; MONOCROTALINE; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SEROTONIN TRANSPORTER; VASCULOTROPIN A;

ADULT; ARTICLE; DISEASE ASSOCIATION; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEART CATHETERIZATION; HEART RIGHT VENTRICLE HYPERTROPHY; HUMAN; IN VITRO STUDY; LUNG ANGIOGRAPHY; LUNG VASCULAR RESISTANCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY ARTERY OCCLUSION PRESSURE; PULMONARY HYPERTENSION; SLEDAI; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTOLIC BLOOD PRESSURE; VASCULAR REMODELING; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; CELL PROLIFERATION; CHEMICALLY INDUCED; COHORT ANALYSIS; COMPLICATION; CYTOLOGY; DISEASE MODEL; GENE EXPRESSION PROFILING; GENETICS; HYPERTENSION, PULMONARY; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PERMEABILITY; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADULT; ANIMALS; AUTOANTIBODIES; CELL PROLIFERATION; COHORT STUDIES; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; HYPERTENSION, PULMONARY; IN VITRO TECHNIQUES; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; MONOCROTALINE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PERMEABILITY; PROTO-ONCOGENE PROTEINS C-SIS; RATS; RECEPTOR, ENDOTHELIN A; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RNA, MESSENGER; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84940118392     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39212     Document Type: Article

References (30)

1. Chen Y, Chen GL, Zhu CQ, Lu X, Ye S, Yang CD., Severe systemic lupus erythematosus in emergency department: a retrospective single-center study from China. Clin Rheumatol 2011; 30: 1463-9.
2. Chow SL, Chandran V, Fazelzad R, Johnson SR., Prognostic factors for survival in systemic lupus erythematosus associated pulmonary hypertension. Lupus 2012; 21: 353-64.
3. Li M, Wang Q, Zhao J, Li Z, Ye Z, Li C, et al., Chinese SLE Treatment and Research group (CSTAR) registry. II. Prevalence and risk factors of pulmonary arterial hypertension in Chinese patients with systemic lupus erythematosus. Lupus 2014; 23: 1085-91.
4. Hao YJ, Jiang X, Zhou W, Wang Y, Gao L, Wang Y, et al., Connective tissue disease-associated pulmonary arterial hypertension in Chinese patients. Eur Respir J 2014. E-pub ahead of print.
5. Negi VS, Tripathy NK, Misra R, Nityanand S., Antiendothelial cell antibodies in scleroderma correlate with severe digital ischemia and pulmonary arterial hypertension. J Rheumatol 1998; 25: 462-6.
6. Li MT, Ai J, Tian Z, Fang Q, Zheng WJ, Zeng XJ, et al., Prevalence of anti-endothelial cell antibodies in patients with pulmonary arterial hypertension associated with connective tissue diseases. Chin Med Sci J 2010; 25: 27-31.
7. Riemekasten G, Philippeet A, Nather M, Slowinski T, Muller DN, Heidecke H, et al., Involvement of functional auto-antibodies against vascular receptors in systemic sclerosis. Ann Rheum Dis 2011; 70: 530-6.
8. Gunther J, Kill A, Becker MO, Heidecke H, Rademacher J, Siegert E, et al., Angiotensin receptor type 1 and endothelin receptor type A on immune cells mediate migration and the expression of IL-8 and CCL18 when stimulated by autoantibodies from systemic sclerosis patients. Arthritis Res Ther 2014; 16: R65.
9. Farber HW, Loscalzo J., Pulmonary arterial hypertension. N Engl J Med 2004; 351: 1655-65.
10. Giaid A, Yanagisawa M, Langleben D, Michel RP, Levy R, Shennib H, et al., Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med 1993; 328: 1732-9.
11. Rubens C, Ewert R, Halank M, Wensel R, Orzechowski HD, Schultheiss HP, et al., Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension. Chest 2001; 120: 1562-9.
12. Humbert M, Morrell NW, Archer SL, Stenmark KR, MacLean MR, Lang IM, et al., Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol 2004; 16: 13-24.
13. Yock PG, Popp RL., Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation. Circulation 1984; 70: 657-62.
14. Hoeper MM, Bogaard HJ, Condliffe R, Frantz R, Khanna D, Kurzyna M, et al., Definitions and diagnosis of pulmonary hypertension. J Am Coll Cardiol 2013; 25 Suppl: D42-50.
15. Hochberg MC, for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997; 40: 1725.
16. Blank M, Cohen J, Toder V, Shoenfeld Y., Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies. Proc Natl Acad Sci U S A 1991; 88: 3069-73.
17. Lee JH, Lee DS, Kim EK, Choe KH, Oh YM, Shim TS, et al., Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs. Am J Respir Crit Care Med 2005; 172: 987-93.
18. White RJ, Meoli DF, Swarthout RF, Kallop DY, Galaria II, Harvey JL, et al., Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol 2007; 293: 583-590.
19. Xi B, Wang TX, Li N, Wei OY, Zhang W, Wu JY, et al., Functional cardiotoxicity profiling and screening using the xCELLigence RTCA cardio system. J Lab Autom 2011; 16: 415-22.
20. Li XC, Milena S, Bonder CS, Hahn CN, Parsons M, Pitson SM, et al., Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1. Blood 2008; 111: 3489-97.
21. Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang DH, and the Committee on Prognosis Studies in SLE. Derivation of the SLEDAI: a disease activity index for lupus patients. Arthritis Rheum 1992; 35: 630-40.
22. Artim-Esen B, Cene E, Sahinkaya Y, Ertan S, Pehlivan O, Kamali S, et al., Cluster analysis of autoantibodies in 852 patients with systemic lupus erythematosus from a single center. J Rheumatol 2014; 41: 1304-10.
23. Li J, Leng XM, Li ZJ, Ye ZZ, Li CF, Li XF, et al., Chinese SLE treatment and research group registry. III. Association of autoantibodies with clinical manifestations in Chinese patients with systemic lupus erythematosus. J Immunol Res 2014. E-pub ahead of print.
24. Becker MO, Kill A, Kutsche M, Guenther J, Rose A, Tabeling C, et al., Vascular receptor autoantibodies in pulmonary arterial hypertension associated with systemic sclerosis. Am J Respir Crit Care Med 2014;190:808-17.
25. Gomez-Arroyo JG, Farkas L, Alhussaini AA, Farkas D, Kraskauskas D, Voelkel NF, et al., The monocrotaline model of pulmonary hypertension in perspective. Am J Physiol Lung Cell Mol Physiol 2012; 302: 363-9.
26. Rohit B, Rubin M, Paul M., Endothelial dysfunction in pulmonary hypertension. Circulation 2004; 109: 159-65.
27. Guignabert C, Raffestin B, Benferhat R, Raoul W, Zadigue P, Rideau D, et al., Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats. Circulation 2005; 111: 2812-9.
28. Schermuly RT, Dony E, Ghofrani HA, Pullamsetti S, Savai R, Roth M, et al., Reversal of experimental pulmonary hypertension by PDGF inhibition. J Clin Invest 2005; 115: 2811-21.
29. Han DD, Wang Y, Zhang XH, Liu JR, Wang HL., Fluoxetine protects against monocrotaline-induced pulmonary arterial remodeling by inhibition of hypoxia-inducible factor-1α and vascular endothelial growth factor. Can J Physiol Pharmacol 2012; 90: 445-54.
30. Polonio IB, Acencio MM, Pazetti R, Almeida FM, Canzian M, Silva BS, et al., Comparison of two experimental models of pulmonary hypertension. J Bras Pneumol 2012; 38: 452-60.