Vitamin D, serum 25(OH)D, LL-37 and polymorphisms in a canadian first nation population with endemic tuberculosis

International Journal of Circumpolar Health

Volumn 74, Issue , 2015, Pages

  Larcombe, Linda ^a   Mookherjee, Neeloffer ^a,b   Slater, Joyce ^a   Slivinski, Caroline ^a   Dantouze, Joe ^c   Singer, Matthew ^a   Whaley, Chris ^a   Denechezhe, Lizette ^c   Matyas, Sara ^a   Decter, Kate ^a   Turner Brannen, Emily ^a   Ramsey, Clare ^a   Nickerson, Peter ^a,b   Orr, Pamela ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c Northlands Denesuline First Nation   (Canada)

Author keywords

10.3402 ijch.v74.28952; Cathelicidin (LL 37); Genetics; Indigenous; Tuberculosis; Vitamin D

Indexed keywords

25-HYDROXYVITAMIN D; ANTIMICROBIAL CATIONIC PEPTIDE; CALCITRIOL RECEPTOR; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; GENETIC MARKER; VITAMIN D; VITAMIN D BINDING PROTEIN;

ADULT; ANALOGS AND DERIVATIVES; BLOOD; CANADA; COHORT ANALYSIS; COMPARATIVE STUDY; ENDEMIC DISEASE; FEMALE; GENETIC MARKER; GENETICS; HUMAN; INCIDENCE; MALE; MIDDLE AGED; POPULATION GROUP; PROSPECTIVE STUDY; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; TUBERCULOSIS;

ADULT; ANTIMICROBIAL CATIONIC PEPTIDES; CANADA; COHORT STUDIES; ENDEMIC DISEASES; FEMALE; GENETIC MARKERS; HUMANS; INCIDENCE; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; POPULATION GROUPS; PROSPECTIVE STUDIES; RECEPTORS, CALCITRIOL; RISK ASSESSMENT; TUBERCULOSIS; VITAMIN D; VITAMIN D-BINDING PROTEIN;

EID: 84940099548     PISSN: 12399736     EISSN: 22423982     Source Type: Journal    
DOI: 10.3402/ijch.v74.28952     Document Type: Article

References (36)

1. Lodge A, Orr P, Larcombe L, Denechezhe L, Oakley L, Martin B, editors. Tuberculosis in a remote Canadian Dené community: the impact of virulence, genetic and environmental factors on epidemiology and control. Congress on 13th International Circumpolar Health, Novosibirsk, Siberia; 2006.
2. Orr P. Tuberculosis in Nunavut: looking back, moving forward. CMAJ. 2013;185:287-8.
3. Roth DE, Jones AB, Prosser C, Robinson JL, Vohra S. Vitamin D receptor polymorphisms and the risk of acute lower respiratory tract infection in early childhood. J Infect Dis. 2008;197:676-80.
4. National Collaborating Centre for Aboriginal Health. The state of knowledge of Aboriginal health: a review of Aboriginal public health in Canada. 2013 [cited 2013 November 25]. Available from: http://www.activecircle.ca/files/resources/SOK_ report_EN_web.pdf
5. Larcombe L, Mookherjee N, Slater J, Slivinski C, Singer M, Whaley C, et al. Vitamin D in a northern Canadian First Nation population: dietary intake, serum concentrations and functional gene polymorphisms. PLoS One. 2012;7:e49872.
6. Slater J, Larcombe L, Green C, Slivinski C, Singer M, Denechezhe L, et al. Vitamin D and the nutrition transition in a northern Dene community. Int J Circumpolar Health. 2013;72:20723, doi: http://dx.doi.org/10.3402/ijch.v72i0.20723
7. Weiler HA, Leslie WD, Krahn J, Steiman PW, Metge CJ. Canadian Aboriginal women have a higher prevalence of vitamin D deficiency than non-Aboriginal women despite similar dietary vitamin D intakes. J Nutr. 2007;137:461-5.
8. Nnoaham KE, Clarke A. Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis. Int J Epidemiol. 2008;37:113-9.
9. Martineau AR, Wilkinson RJ, Wilkinson KA, Newton SM, Kampmann B, Hall BM, et al. A single dose of vitamin D enhances immunity to mycobacteria. Am J Respir Crit Care Med. 2007;176:208-13.
10. Wilkinson RJ, Llewelyn M, Toossi Z, Patel P, Pasvol G, Lalvani A, et al. Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case_control study. Lancet. 2000;355: 618-21.
11. Poliquin S, Joseph L, Gray-Donald K. Calcium and vitamin D intakes in an adult Canadian population. Can J Diet Pract Res. 2009;70:21-7.
12. Frost P. Vitamin D deficiency among northern Native Peoples: a real or apparent problem? Int J Circumpolar Health. 2012;71:18001, doi: http://dx/doi.org/10.3402/ijch.v71i0.18001
13. Hewison M. An update on vitamin D and human immunity. Clin Endocrinol (Oxf). 2012;76:315-25.
14. Olson L. A comparative study on the incidence of tuberculosis among status Indians and other selected groups in Manitoba, Canada. Winnipeg, MB: University of Manitoba; 1999.
15. Larcombe L, Orr P, Turner-Brannen E, Slivinski CR, Nickerson PW, Mookherjee N. Effect of vitamin D supplementation on Mycobacterium tuberculosis-induced innate immune responses in a Canadian Dene First Nations cohort. PLoS One. 2012; 7:e40692.
16. Adams JS, Hewison M. Update in vitamin D. J Clin Endocrinol Metab. 2010;95:471-8.
17. Gombart AF, Bhan I, Borregaard N, Tamez H, Camargo CA., Jr., Koeffler HP, et al. Low plasma level of cathelicidin antimicrobial peptide (hCAP18) predicts increased infectious disease mortality in patients undergoing hemodialysis. Clin Infect Dis. 2009;48:418-24.
18. Wang TT, Nestel FP, Bourdeau V, Nagai Y, Wang Q, Liao J, et al. Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol. 2004;173:2909-12.
19. Martineau AR, Wilkinson KA, Newton SM, Floto RA, Norman AW, Skolimowska K, et al. IFN-g and TNF-independent vitamin D-inducible human suppression of Mycobacteria: the role of cathelicidin LL-37. J Immunol. 2007;178:7190-8.
20. Gombart AF. The vitamin D-antimicrobial peptide pathway and its role in protection against infection. Future Microbiol. 2009;4:1151-65.
21. Choi KY, Chow LN, Mookherjee N. Cationic host defence peptides: multifaceted role in immune modulation and inflammation. J Innate Immun. 2012;4:361-70.
22. Chun RF, Lauridsen AL, Suon L, Zella LA, Pike JW, Modlin RL, et al. Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D. J Clin Endocrinol Metab. 2010;95:3368-76.
23. Janssens W, Bouillon R, Claes B, Carremans C, Lehouck A, Buysschaert I, et al. Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax. 2010;65:215-20.
24. Engelman CD, Fingerlin TE, Langefeld CD, Hicks PJ, Rich SS, Wagenknecht LE, et al. Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African Americans. J Clin Endocrinol Metab. 2008;93:3381-8.
25. Ahn J, Albanes D, Berndt SI, Peters U, Chatterjee N, Freedman ND, et al. Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk. Carcinogenesis. 2009;30: 769-76.
26. First Nations Centre. OCAP: Ownership, Control, Access and Possession. Sanctioned by the First Nations Information Governance Committee, Assembly of first Nations. Ottawa: National Aboriginal Health Organization; 2007.
27. Census Profiles [Internet]. 2006 [cited 2012 December 8]. Available from: http://www12.statcan.gc.ca/census-recensement/ index-eng.cfm
28. TheCanadianNutrient File [Internet]. 2007 [cited 2010 September 10]. Available from: http://www.hc-sc.gc.ca/fn-an/nutrition/fichenutri- data/cnf_aboutus-aproposdenous_fcen-eng.php
29. Statistics Canada. Vitamin D status of Canadians as measured in the 2007 to 2009. Canadian health measures survey. 2009 [cited 2011 November 6]. Available from: http://www.statcan. gc.ca/pub/82-625-x/2010001/article/11137-eng.htm
30. Lauridsen AL, Vestergaard P, Nexo E. Mean serum concentration of vitamin D-binding protein (Gc globulin) is related to the Gc phenotype in women. Clin Chem. 2001;47:753-6.
31. Arnaud J, Constans J. Affinity differences for vitamin D metabolites associated with the genetic isoforms of the human serum carrier protein (DBP). Hum Genet. 1993;92:183-8.
32. Bergman P, Norlin AC, Hansen S, Rekha RS, Agerberth B, Bjorkhem-Bergman L, et al. Vitamin D3 supplementation in patients with frequent respiratory tract infections: a randomised and double-blind intervention study. BMJ Open. 2012; 2:pii:e001663.
33. Das M, Tomar N, Sreenivas V, Gupta N, Goswami R. Effect of vitamin D supplementation on cathelicidin, IFN-gamma, IL-4 and Th1/Th2 transcription factors in young healthy females. Eur J Clin Nutr. 2014;68:338-43.
34. Dixon B, Barker T, McKinnon T, Cuomo J, Frei B, Borregaard N, et al. Postivie correlation between circulating cathelididin antimicrobial peptide (hCAP18/LL-37) and 25-hydroxyvitamin D levels in healthy adults. BMC Res Notes. 2012;5:575.
35. Bhan I, Camargo CA, Jr., Wenger J, Ricciardi C, Ye J, Borregaard N, et al. Circulating levels of 25-hydroxyvitamin D and human cathelicidin in healthy adults. J Allergy Clin Immunol. 2011;127:1302-4.e1.
36. Larcombe L, Nickerson P, Singer M, Robson R, Dantouze J, McKay L, et al. Housing conditions in 2 Canadian First Nations communities. Int J Circumpolar Health. 2011;70:141-53.