Epidural analgesia does not influence anastomotic leakage incidence after open colorectal surgery for cancer: A retrospective study on 1,474 patients

Journal of Surgical Oncology

Volumn 112, Issue 2, 2015, Pages 225-230

  Piccioni, Federico ^a   Mariani, Luigi ^a   Negri, Marta ^b   Casiraghi, Claudia ^c   Belli, Filiberto ^a   Leo, Ermanno ^a   Langer, Martin ^a,c  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b TREVIGLIO HOSPITAL   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

analgesia; anastomotic leak; cancer; colorectal; epidural; pain; postoperative

Indexed keywords

ANESTHETIC AGENT;

ADULT; AGED; ANASTOMOSIS LEAKAGE; ARTICLE; CANCER PATIENT; COLORECTAL CANCER; COLORECTAL SURGERY; ELECTIVE SURGERY; EPIDURAL ANESTHESIA; FEMALE; HUMAN; INCIDENCE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE ANALGESIA; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REOPERATION; RETROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; SURGICAL MORTALITY; TERTIARY CARE CENTER; ADVERSE EFFECTS; ANASTOMOTIC LEAK; COLON RESECTION; COLORECTAL NEOPLASMS; ITALY; MIDDLE AGED;

ADULT; AGED; ANALGESIA, EPIDURAL; ANASTOMOTIC LEAK; COLECTOMY; COLORECTAL NEOPLASMS; FEMALE; HUMANS; INCIDENCE; ITALY; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84940048666     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.23966     Document Type: Article

References (36)

1. Buchs NC, Gervaz P, Secic M, et al.,: Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: A prospective monocentric study. Int J Colorectal Dis 2008; 23: 265-270.
2. Nesbakken A, Nygaard K, Lunde OC,: Outcome and late functional results after anastomotic leakage following mesorectal excision for rectal cancer. Br J Surg 2001; 88: 400-404.
3. Rodgers A, Walker N, Schug S, et al.,: Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: Results of overview of randomized trials. Br Med J 2000; 321: 1-12.
4. Popping DM, Elia N, Marret E, et al.,: Protective effects of epidural analgesia on pulmonary complications after abdominal and thoracic surgery: A meta-analysis. Arch Surg 2008; 143: 990-999.
5. Freise H, Van Haken HK,: Risks and benefits of thoracic epidural anaesthesia. Br J Anaesth 2011; 107: 859-868.
6. Gustafsson UO, Scott MJ, Schwenk W, et al.,: Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. World J Surg 2013; 37: 259-284.
7. Nygren J, Thacker J, Carli F, et al.,: Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations. World J Surg 2013; 37: 285-305.
8. Sielenkamper AW, Eicker K, Van Aken H,: Thoracic epidural anaesthesia increases mucosal perfusion in ileum of rats. Anesthesiology 2000; 93: 844-851.
9. Bigler D, Hjortso NC, Kehelt H,: Disruption of colonic anastomosis during continuous epidural analgesia. Anaesthesia 1985; 40: 278-280.
10. Mann C, Pouzeratte Y, Boccara G, et al.,: Comparison of intravenous or epidural patient-controlled analgesia in the elderly after major abdominal surgery. Anesthesiology 2000; 92: 433-441.
11. Carli F, Mayo N, Trudel J,: Epidural analgesia enhances functional exercise capacity and health-related quality of life after colonic surgery. Anesthesiology 2002; 97: 540-549.
12. Rimaitis K, Marchertiene I, Pavalkis D,: Comparison of two different methods of analgesia. Postoperative course after colorectal cancer surgery. Medicina (Kaunas) 2003; 39: 129-137.
13. Warschkow R, Steffen T, Lüthi A, et al.,: Epidural analgesia in open resection of colorectal cancer: Is there a clinical benefit? A retrospective study on 1,470 patients. J Gastrointest Surg 2011; 15: 1386-1393.
14. Marret E, Remy C, Bonnet F,: Meta-analysis of epidural analgesia versus parenteral opioid analgesia after colorectal surgery. Br J Surg 2007; 94: 665-673.
15. Halabi WJ, Jafari MD, Nguyen VQ, et al.,: A nationwide analysis of the use and outcomes of epidural analgesia in open colorectal surgery. J Gastrointest Surg 2013; 17: 1130-1137.
16. Matthiessen P, Hallbook O, Andersson M, et al.,: Risk factors for anastomotic leakage after anterior resection of the rectum. Colorectal Dis 2004; 6: 462-469.
17. Rudinskaite G, Tamelis A, Saladzinskas Z, et al.,: Risk factors for clinical anastomotic leakage following the resection of sigmoid and rectal cancer. Medicina (Kaunas) 2005; 41: 741-746.
18. Konishi T, Watanabe T, Kishimoto J, et al.,: Risk factors for anastomotic leakage after surgery for colorectal cancer: Results of prospective surveillance. J Am Coll Surg 2006; 202: 439-444.
19. Lipska MA, Bissett IP, Parry BR, et al.,: Anastomotic leakage after lower gastrointestinal anastomosis: Men are at a higher risk. ANZ J Surg 2006; 76: 579-585.
20. Jestin P, Påhlman L, Gunnarsson U,: Risk factors for anastomotic leakage after rectal cancer surgery: A case-control study. Colorectal Dis 2008; 10: 715-721.
21. Yang L, Huang XE, Zhou JN,: Risk assessment on anastomotic leakage after rectal cancer surgery: An analysis of 753 patients. Asian Pac J Cancer Prev 2013; 14: 4447-4453.
22. Krarup PM, Jorgensen LN, Andreasen AH, et al.,: A nationwide study on anastomotic leakage after colonic cancer surgery. Colorectal Dis 2012; 14: 661-667.
23. Leichtle SW, Mouawad NJ, Welch KB, et al.,: Risk factors for anastomotic leakage after. Dis Colon Rectum 2012; 55: 569-575.
24. Post IL, Verheijen PM, Pronk A, et al.,: Intraoperative blood pressure changes as a risk factor for anastomotic leakage in colorectal surgery. Int J Colorectal Dis 2012; 27: 765-772.
25. Phitayakorn R, Delaney CP, Reynolds HL, et al.,: Standardized algorithms for management of anastomotic leaks and related abdominal and pelvic abscesses after colorectal surgery. World J Surg 2008; 43: 578-589.
26. Daams F, Luyer M, Lange JF,: Colorectal anastomotic leakage: Aspect of prevention, detection and treatment. World J Gastroent 2013; 19: 2293-2297.
27. Dindo D, Demartines N, Clavien PA,: Classification of surgical complications. A new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 2004; 240: 205-213.
28. Paulsen EK, Porter MG, Helmer SD, et al.,: Thoracic epidural versus patient-controlled analgesia in elective bowel resections. Am J Surg 2001; 182: 570-577.
29. Trencheva K, Morrissey KP, Wells M, et al.,: Identifying important predictors for anastomotic leak after colon and rectal resection: Prospective study on 616 patients. Ann Surg 2013; 257: 108-113.
30. Telem DA, Chin EH, Nguyen SQ, et al.,: Risk factors for anastomotic leak following colorectal surgery. Arch Surg 2010; 145: 371-376.
31. Charlson ME, Pompei P, Ales KL, et al.,: A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis 1987; 40: 373-383.
32. Montedori A, Cirocchi R, Farinella E, et al.,: Covering ileo- or colostomy in anterior resection for rectal carcinoma. Cochrane Database Syst Rev 2010; 12: 1-17.
33. Kang CY, Halabi WJ, Chaudhry OO, et al.,: Risk factors for anastomotic leakage after anterior resection for rectal cancer. JAMA Surg 2013; 148: 65-71.
34. Shi WZ, Miao YL, Yakoob MY, et al.,: Recovery of gastrointestinal function with thoracic epidural vs. systemic analgesia following gastrointestinal surgery. Acta Anaesthesiol Scand 2014; 58: 923-932.
35. Popping DM, Elia N, Van Aken HK, et al.,: Impact of epidural analgesia on mortality and morbidity after surgery: Systematic review and meta-analysis of randomized controlled trials. Ann Surg 2014; 259: 1056-1067.
36. Hugghes MJ, Ventham NT, McNally S, et al.,: Analgesia after open abdominal surgery in the setting of enhanced recovery surgery: A systematic review and meta-analysis. JAMA Surg 2014; 149: 1224-1230.