Blood Cultures Are Not Useful in the Evaluation of Children with Uncomplicated Superficial Skin and Soft Tissue Infections

Pediatric Infectious Disease Journal

Volumn 34, Issue 9, 2015, Pages 924-927

  Trenchs, Victoria ^a   Hernandez Bou, Susanna ^a   Bianchi, Claudia ^a   Arnan, Mireia ^a   Gene, Amadeu ^a   Luaces, Carles ^a  

^a HOSPITAL SANT JOAN DE DÉU   (Spain)

Author keywords

abscess; bacteremia; blood culture; cellulitis

Indexed keywords

ANTIBIOTIC AGENT;

ABSCESS; ADULT; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BLOOD CULTURE; BURN; CELLULITIS; CHILD; CLINICAL EVALUATION; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; EMERGENCY WARD; ERYSIPELAS; FEMALE; HOSPITAL ADMISSION; HUMAN; IMPETIGO; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SOFT TISSUE INFECTION; STAPHYLOCOCCAL SKIN INFECTION; STREPTOCOCCUS PYOGENES; ULCER; WOUND INFECTION; BLOOD; EVALUATION STUDY; INFANT; ISOLATION AND PURIFICATION; LABORATORY DIAGNOSIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; PROCEDURES; SKIN DISEASES, BACTERIAL; SOFT TISSUE INFECTIONS;

BLOOD; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIOLOGICAL TECHNIQUES; RETROSPECTIVE STUDIES; SKIN DISEASES, BACTERIAL; SOFT TISSUE INFECTIONS; SPECIMEN HANDLING; STREPTOCOCCUS PYOGENES;

EID: 84940047149     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0000000000000768     Document Type: Article

References (26)

1. Sadow KB, Chamberlain JM. Blood cultures in the evaluation of children with cellulitis. Pediatrics. 1998;101:E4.
2. Doctor A, Harper MB, Fleisher GR. Group A beta-hemolytic streptococcal bacteremia: historical overview, changing incidence, and recent association with varicella. Pediatrics. 1995;96(3 Pt 1):428-433.
3. Malone JR, Durica SR, Thompson DM, et al. Blood cultures in the evaluation of uncomplicated skin and soft tissue infections. Pediatrics. 2013;132:454-459.
4. Wathen D, Halloran DR. Blood culture associations in children with a diagnosis of cellulitis in the era of methicillin-resistant Staphylococcus aureus. Hosp Pediatr. 2013;3:103-107.
5. Khangura S, Wallace J, Kissoon N, et al. Management of cellulitis in a pediatric emergency department. Pediatr Emerg Care. 2007;23:805-811.
6. Stevenson A, Hider P, Than M. The utility of blood cultures in the management of non-facial cellulitis appears to be low. N Z Med J. 2005;118:U1351.
7. Mistry RD, Shapiro DJ, Goyal MK, et al. Clinical management of skin and soft tissue infections in the U.S. emergency departments. West J Emerg Med. 2014;15:491-498.
8. Ray GT, Suaya JA, Baxter R. Microbiology of skin and soft tissue infections in the age of community-acquired methicillin-resistant Staphylococcus aureus. Diagn Microbiol Infect Dis. 2013;76:24-30.
9. Chira S, Miller LG. Staphylococcus aureus is the most common identified cause of cellulitis: a systematic review. Epidemiol Infect. 2010;138: 313-317.
10. Merritt C, Haran JP, Mintzer J, et al. All purulence is local-epidemiology and management of skin and soft tissue infections in three urban emergency departments. BMC Emerg Med. 2013;13:26.
11. Awad SS, Elhabash SI, Lee L, et al. Increasing incidence of methicillinresistant Staphylococcus aureus skin and soft-tissue infections: reconsideration of empiric antimicrobial therapy. Am J Surg. 2007;194:606-610.
12. Moet GJ, Jones RN, Biedenbach DJ, et al. Contemporary causes of skin and soft tissue infections in North America, Latin America, and Europe: report from the SENTRY Antimicrobial Surveillance Program (1998-2004). Diagn Microbiol Infect Dis. 2007;57:7-13.
13. Iwamoto M, Mu Y, Lynfield R, et al. Trends in invasive methicillin-resistant Staphylococcus aureus infections. Pediatrics. 2013;132:e817-e824
14. Astete JA, Batlle A, Hernandez-Bou S, et al. Blood culture diagnostic yield in a paediatric emergency department. Eur J Emerg Med. 2014;21:336-340.
15. Vindel A, Trincado P, Cuevas O, et al. Molecular epidemiology of community-associated methicillin-resistant Staphylococcus aureus in Spain: 2004-12. J Antimicrob Chemother. 2014;69:2913-2919.
16. Fricka MA, Moraga-Llop FA, Bartolomé R et al. Infecciones por Staphylococcus aureus resistente a meticilina adquirido en la comunidad en niños. Enferm Infecc Microbiol Clin. 2010;28:675-679.
17. Chaves F. Emergencia de infecciones pediátricas por Staphylococcus aureus resistente a meticilina asociadas a la comunidad: ¿debemos dar la alerta? Enferm Infecc Microbiol Clin. 2010;28:672-674.
18. Dieckmann RA, Brownstein D, Gausche-Hill M. The pediatric assessment triangle: a novel approach for the rapid evaluation of children. Pediatr Emerg Care. 2010;26:312-315.
19. Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59:e10-e52.
20. Saavedra Lozano J, Santos Sebastián M, González F, et al. Infecciones bacterianas de la piel y tejidos blandos. In: Asociación Española de Pediatría, Sociedad Española de Infectología Pediátrica, eds. Protocolos diagnósticoterapéuticos de la AEP: Infectología Pediátrica. Protocolos de Infectología. Serie: protocolos de la AEP. 3rd ed. Madrid: Ergon; 2011: 159-175. Available at: http://www.aeped.es/sites/default/files/documentos/piel.pdf. Accessed November 19, 2014.
21. Salgado Ordóñez F, Arroyo Nieto A, Lozano Serrano AB, et al. Infecciones de piel y partes blandas. Med Clin (Barc). 2009;133:552-564.
22. Kam AJ, Leal J, Freedman SB. Pediatric cellulitis: success of emergency department short-course intravenous antibiotics. Pediatr Emerg Care. 2010;26:171-176.
23. Bates DW, Goldman L, Lee TH. Contaminant blood cultures and resource utilization. The true consequences of false-positive results. JAMA. 1991;265:365-369.
24. Segal GS, Chamberlain JM. Resource utilization and contaminated blood cultures in children at risk for occult bacteremia. Arch Pediatr Adolesc Med. 2000;154:469-473.
25. Hernandez-Bou S, Trenchs V, Batlle A, et al. Occult bacteremia is uncommon in febrile infants who appear well, and close clinical follow-up is more appropriate than blood tests. Acta Paediatr. 2014;104:e76-e81.
26. Casado-Verrier B, Gómez-Fernández C, Pano-Pardo JR, et al. Prevalencia de infecciones de piel y tejidos blandos producidas por Staphylococcus aureus resistente a meticilina comunitario en Madrid. Enferm Infecc Microbiol Clin. 2012;30:300-306.