Selective Analysis of Dopamine Receptor Antagonist LE300 and its N-Methyl Metabolite in Mouse Sera at the Trace Level by HPLC–Fluorescence Detection

Chromatographia

Volumn 78, Issue 9-10, 2015, Pages 655-661

  Hefnawy, Mohamed ^a   Alanazi, Amer ^a   Abounassif, Mohammed ^a   Mohammed, Mostafa ^a   Al Swaidan, Ibrahim ^a   Attia, Sabry ^a   Mostafa, Gamal ^a   El Subbagh, Hussein ^b   Lehmann, Jochen ^c  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b MANSOURA UNIVERSITY   (Egypt)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Fluorescence detection; HPLC; LE300; Pharmacokinetics; Trace analysis

Indexed keywords

EID: 84939984346     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1007/s10337-015-2879-x     Document Type: Article

References (14)

1. Decker M, Schleifer KJ, Nieger M, Lehmann J (2004) Eur J Med Chem 39:481–489
2. Hoefgen B, Decker M, Mohr P, Schramm AM, Rostom SAF, El-Subbagh H, Schweikert PM, Rudolf, Kassack MU, Lehmann J (2006) J Med Chem 49:760–769
3. Kassack MU, Höfgen B, Decker M, Eckstein N, Lehmann J (2002) NauSchmi Arch Pharm 366:543–550
4. Emilien G, Maloteaux JM, Geurts M, Hoogenberg K, Cragg S (1999) Pharmacol Ther 84:133–156
5. Robaa D, Kretschmer R, Siol O, AbulAzm S, Elkhawass E, Lehmann J, Enzensperger C (2011) Arch Pharm Chem Life Sci 1:28–36
6. Hubert P, Nguyen-Huu JJ, Boulanger B, Chapuzet E, Chiap P, Cohen N, Compagnon PA, Dewe W, Feinberg M, Lallier M, Laurentie M, Mercier N, Muzard G, Nivet C, Valat L, Rozet E (2007) J Pharm Biomed 45:70–81
7. Sennbro CJ, Knutsson M, Timmerman P, van Amsterdam P (2011) Bioanalysis 3:2389–2399
8. González O, Blanco ME, Iriarte G, Bartolomé L, Maguregui MI, Alonso RM (2014) J Chromatogr A 1353:10–27
9. ISO (2005) ISO/IEC17025: General requirements for the competence of testing and calibration laboratories. International Organisation for Standardisation, Geneva
10. ISO (2012) ISO/IEC15819: Medical laboratories—particular requirements for quality and competence. International Organisation for Standardisation, Geneva
11. US FDA (1999) Draft guidance for industry: bioanalytical method validation. US Food and Drug Administration, Rockville
12. Gibson GG, Skett P (2001) Introduction to drug metabolism. Nelson Thornes, Cheltenham
13. ICH (1996) Q2B validation of analytical procedures: methodology. International Conference on Harmonization (ICH), Geneva
14. Miller JC, Miller JN (2005) 2nd edn. Ellis Horwood, Chichester