Clinical associations of white matter damage in cART-treated HIV-positive children in South Africa

Journal of NeuroVirology

Volumn 21, Issue 2, 2015, Pages 120-128

  Hoare, Jacqueline ^a   Fouche, Jean Paul ^a   Phillips, Nicole ^a   Joska, John A ^a   Donald, Kirsten A ^a   Thomas, Kevin ^a   Stein, Dan J ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Cognitive impairment; Diffusion tensor; HIV AIDS; Imaging; Pediatric

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ADOLESCENT; BRAIN; CHILD; COMPUTER ASSISTED DIAGNOSIS; DIFFUSION TENSOR IMAGING; FEMALE; HIV INFECTIONS; HUMAN; MALE; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; SOUTH AFRICA; WHITE MATTER;

ADOLESCENT; ANTI-HIV AGENTS; BRAIN; CHILD; DIFFUSION TENSOR IMAGING; FEMALE; HIV INFECTIONS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MALE; NEUROPSYCHOLOGICAL TESTS; SOUTH AFRICA; WHITE MATTER;

EID: 84939982483     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-014-0311-1     Document Type: Article

References (35)

1. Angelini L, Zibordi F, Triulzi F et al (2000) Age-dependent neurologic manifestations of HIV infection in childhood. Neurol Sci 21:135–142. doi:10.1007/s100720070088
2. Bagga D, Sharma A, Kumari A et al (2013) Decreased white matter integrity in fronto-occipital fasciculus bundles: relation to visual information processing in alcohol-dependent subjects. Alcohol. doi:10.1016/j.alcohol.2013.10.009
3. Benjamini Y, Hochberg Y. (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B 57(1)289–300
4. Benton D, ILSI Europe a.i.s.b.l. (2008) Micronutrient status, cognition and behavioral problems in childhood. Eur J Nutr 47:38–50. doi:10.1007/s00394-008-3004-9
5. Bhowmik A, Bhandari S, De R, Guha SK (2012) Predictors of mortality among HIV-infected patients initiating anti retroviral therapy at a tertiary care hospital in eastern India. Asian Pac J Trop Med 5:986–990. doi:10.1016/S1995-7645(12)60187-4
6. Brouwers P, Civitello L, DeCarli C (2000) Cerebrospinal fluid viral load is related to cortical atrophy and not to intracerebral calcifications in children with symptomatic HIV disease. J Neurovirol 6(5):390–397
7. DeCarli C, Civitello L, Moss H, Wolters P (1995) Correlation between computed tomographic brain scan abnormalities and neuropsychological function in children with symptomatic human immunodeficiency. Arch Neurol 52(1):39–44. doi:10.1001/archneur.1995.00540250043011
8. Dusingize J-C, Hoover DR, Shi Q et al (2012) Association of serum albumin with markers of nutritional status among HIV-infected and uninfected Rwandan women. PLoS ONE 7:e35079. doi:10.1371/journal.pone.0035079
9. Feldman JG, Gange SJ, Bacchetti P et al (2003) Serum albumin is a powerful predictor of survival among HIV-1-infected women. J Acquir Immune Defic Syndr 33:66–73
10. Feldman HM, Yeatman JD, Lee ES et al (2010) Diffusion tensor imaging: a review for pediatric researchers and clinicians. J Dev Behav Pediatr 31:346–356. doi:10.1097/DBP.0b013e3181dcaa8b
11. Friis H (2006) Micronutrient interventions and HIV infection: a review of current evidence. Tropical Med Int Health 11:1849–1857. doi:10.1111/j.1365-3156.2006.01740.x
12. Govender R, Eley B, Walker K et al (2011) Neurologic and neurobehavioral sequelae in children with human immunodeficiency virus (HIV-1) infection. J Child Neurol 26:1355–1364. doi:10.1177/0883073811405203
13. Hoare J, Fouche J-P, Spottiswoode B et al (2011) White-matter damage in clade C HIV-positive subjects: a diffusion tensor imaging study. J Neuropsychiatry Clin Neurosci 23:308–315. doi:10.1176/appi.neuropsych.23.3.308
14. Hoare J, Fouche J-P, Spottiswoode B et al (2012) A diffusion tensor imaging and neurocognitive study of HIV-positive children who are HAART-naïve "slow progressors". J Neurovirol 18:205–212. doi:10.1007/s13365-012-0099-9
15. Kinnunen KM, Greenwood R, Powell JH et al (2011) White matter damage and cognitive impairment after traumatic brain injury. Brain 134:449–463. doi:10.1093/brain/awq347
16. Kosalaraksa P, Bunupuradah T, Vonthanak S et al (2012) Prevalence of anemia and underlying iron status in naive antiretroviral therapy HIV-infected children with moderate immune suppression. AIDS Res Hum Retrovir 28:1679–1686. doi:10.1089/AID.2011.0373
17. Mitchell W (2001) Neurological and developmental effects of HIV and AIDS in children and adolescents. Ment Retard Dev Disabil Res Rev 7:211–216. doi:10.1002/mrdd.1029
18. Mofenson LM, Harris DR, Moye J et al (2003) Alternatives to HIV-1 RNA concentration and CD4 count to predict mortality in HIV-1-infected children in resource-poor settings. Lancet 362:1625–1627. doi:10.1016/S0140-6736(03)14825-8
19. Mori S, Wakana S, Nagae-Poetscher L and van Zijl P (2005) MRI atlas of human white matter. Elsevier, Amsterdam
20. Pearson DA, McGrath NM, Nozyce M et al (2000) Predicting HIV disease progression in children using measures of neuropsychological and neurological functioning. PEDIATRICS 106:e76. doi:10.1542/peds.106.6.e76
21. Ruel TD, Boivin MJ, Boal HE et al (2012) Neurocognitive and motor deficits in HIV-infected Ugandan children with high CD4 cell counts. Clin Infect Dis 54:1001–1009. doi:10.1093/cid/cir1037
22. Schmithorst VJ, Wilke M, Dardzinski BJ, Holland SK (2001) Correlation of white matter diffusivity and anisotropy with age during childhood and adolescence: a cross-sectional diffusion-tensor MR imaging study. Radiology 222:212–218. doi:10.1148/radiol.2221010626
23. Schmithorst VJ, Wilke M, Dardzinski BJ, Holland SK (2005) Cognitive functions correlate with white matter architecture in a normal pediatric population: a diffusion tensor MRI study. Hum Brain Mapp 26:139–147. doi:10.1002/hbm.20149
24. Sebunya R, Musiime V, Kitaka S, Ndeezi G (2013) Incidence and risk factors for first line anti retroviral treatment failure among Ugandan children attending an urban HIV clinic. AIDS Res Ther 10:25. doi:10.1097/QAI.0b013e318183acae
25. Sigaloff KC, Calis JC, Geelen SP et al (2011) HIV-1-resistance-associated mutations after failure of first-line antiretroviral treatment among children in resource-poor regions: a systematic review. Lancet Infect Dis 11:769–779. doi:10.1016/S1473-3099(11)70141-4
26. Smith R (2006) Effects of perinatal HIV infection and associated risk factors on cognitive development among young children. PEDIATRICS 117:851–862. doi:10.1542/peds. 2005-0804
27. Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, Watkins KE, Ciccarelli O, Cader MZ, Matthews PM and Behrens TE (2006) Tract-based spatial statistics: voxelwise analysis of multisubject diffusion data. Neuroimage 31:1487–1505
28. Song S-K, Sun S-W, Ramsbottom MJ et al (2002) Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. NeuroImage 17:1429–1436. doi:10.1006/nimg.2002.1267
29. Stoodley CJ, Schmahmann JD (2010) Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processing. Cortex 46(7):831–844
30. Sutcliffe CG, van Dijk JH, Munsanje B et al (2011) Risk factors for pre-treatment mortality among HIV-infected children in rural Zambia: a cohort study. PLoS ONE 6:e29294. doi:10.1371/journal.pone.0029294
31. Tardieu M, Mayaux MJ, Seibel N (1995) Cognitive assessment of school-age children infected with maternally transmitted human immunodeficiency virus type 1. J Pediatr 126(3):375–379
32. Vishwas MS, Healy BC, Pienaar R et al (2013) Diffusion tensor analysis of pediatric multiple sclerosis and clinically isolated syndromes. AJNR Am J Neuroradiol 34:417–423. doi:10.3174/ajnr.A3216
33. Ward T, Powell RM, Evans DJ (1999) Serum albumin inhibits echovirus 7 uncoating. J Gen Virol 80(2):283–290
34. Willen EJ (2006) Neurocognitive outcomes in pediatric HIV. Ment Retard Dev Disabil Res Rev 12:223–228. doi:10.1002/mrdd.20112
35. Wu TC, Wilde EA, Bigler ED et al (2009) Longitudinal changes in the corpus callosum following pediatric traumatic brain injury. Dev Neurosci 32:361–373. doi:10.1159/000317058