The use of Design of Experiments and Response Surface Methodology to optimize biomass and lipid production by the oleaginous marine green alga, Nannochloropsis gaditana in response to light intensity, inoculum size and CO2

Bioresource Technology

Volumn 184, Issue , 2015, Pages 161-168

  Hallenbeck, Patrick C ^a   Grogger, Melanie ^a   Mraz, Megan ^a   Veverka, Donald ^a  

^a UNITED STATES AIR FORCE ACADEMY   (United States)

Author keywords

Algae; Biofuels; Lipid production; Medium optimization; Response Surface Methodology

Indexed keywords

ALGAE; BIOFUELS; BIOMASS; DESIGN OF EXPERIMENTS; GALLIUM ALLOYS; LIPIDS; SURFACE PROPERTIES;

BIOMASS PRODUCTIONS; CELLULAR POPULATIONS; LIPID PRODUCTIONS; MEDIUM OPTIMIZATION; MICROALGAL LIPIDS; RENEWABLE ENERGIES; RESPONSE SURFACE METHODOLOGY; VOLUMETRIC PRODUCTION;

CARBON DIOXIDE;

CARBON DIOXIDE; LIPID;

AGE; BIOFUEL; BIOMASS; BIOTECHNOLOGY; CARBON MONOXIDE; FLOW CYTOMETRY; GREEN ALGA; LIGHT INTENSITY; LIPID; METHODOLOGY; OPTIMIZATION;

ARTICLE; BIOMASS; BIOMASS PRODUCTION; CELL SIZE; DRY WEIGHT; FLOW CYTOMETRY; INOCULATION; LIGHT INTENSITY; LIPID STORAGE; NANNOCHLOROPSIS GADITANA; NONHUMAN; PRIORITY JOURNAL; RESPONSE SURFACE METHOD; BIOSYNTHESIS; BIOTECHNOLOGY; CELL CULTURE; DRUG EFFECTS; GREEN ALGA; LIGHT; METABOLISM; METHODOLOGY; PROCEDURES; RADIATION RESPONSE; STRAMENOPILE; TIME;

ALGAE; CHLOROPHYTA; NANNOCHLOROPSIS GADITANA;

BIOMASS; BIOTECHNOLOGY; CARBON DIOXIDE; CELL SIZE; CELLS, CULTURED; CHLOROPHYTA; FLOW CYTOMETRY; LIGHT; LIPIDS; RESEARCH DESIGN; STRAMENOPILES; TIME FACTORS;

EID: 84939980348     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2014.09.022     Document Type: Article

References (31)

1. Abdelaziz A.E.M., Leite G.B., Hallenbeck P.C. Addressing the challenges for sustainable production of algal biofuels: I. Algal strains and nutrient supply. Environ. Technol. 2013, 34:1783-1805.
2. Abdelaziz A.E.M., Leite G.B., Hallenbeck P.C. Addressing the challenges for sustainable production of algal biofuels: II. Harvesting and conversion to biofuels. Environ. Technol. 2013, 34:1807-1836.
3. Abdelaziz A.E.M., Leite G.B., Belhaj M.A., Hallenbeck P.C. Screening microalgae native to Quebec for wastewater treatment and biodiesel production. Bioresour. Technol. 2014, 157:140-148.
4. Anandarajah K., Mahendraperumal G., Sommerfeld M., Hu Q. Characterization of microalga Nannochloropsis sp mutants for improved production of biofuels. Appl. Energy 2012, 96:371-377.
5. Chen Y., Wang J., Liu T., Gao L. Effects of initial population density (IPD) on growth and lipid composition of Nannochloropsis sp. J. Appl. Phycol. 2012, 24:1623-1627.
6. Chi Y., Yasuyuki T., Feng C. Growth performance of two oleaginous microalgae, Nannochloropsis oceanica IMETI and N. gaditana CCMP526 under different cultivation conditions. Phycologia 2013, 52. 17-17.
7. 2 aeration. Bioresour. Technol. 2009, 100:833-838.
8. Corteggiani Carpinelli E., Telatin A., Vitulo N., Forcato C., D'Angelo M., Schiavon R., Vezzi A., Giacometti G.M., Morosinotto T., Valle G. Chromosome scale genome assembly and transcriptome profiling of Nannochloropsis gaditana in nitrogen depletion. Mol. Plant 2014, 7:323-335.
9. Green R.E., Sosik H.M., Olson R.J., DuRand M.D. Flow cytometric determination of size and complex refractive index for marine particles: comparison with independent and bulk estimates. Appl. Opt. 2003, 42:526-541.
10. Hu Q., Sommerfeld M., Jarvis E., Ghirardi M., Posewitz M., Seibert M., Darzins A. Microalgal triacylglycerols as feedstocks for biofuel production: perspectives and advances. Plant J. 2008, 54:621-639.
11. Huang X., Huang Z., Wen W., Yan J. Effects of nitrogen supplementation of the culture medium on the growth, total lipid content and fatty acid profiles of three microalgae (Tetraselmis subcordiformis, Nannochloropsis oculata and Pavlova viridis). J. Appl. Phycol. 2013, 25:129-137.
12. Jinkerson R.E., Radakovits R., Posewitz M.C. Genomic insights from the oleaginous model alga Nannochloropsis gaditana. Bioengineered 2013, 4:37-43.
13. Kilian O., Benemann C.S.E., Niyogi K.K., Vick B. High-efficiency homologous recombination in the oil-producing alga Nannochloropsis sp. Proc. Natl. Acad. Sci. USA 2011, 108:20859-20860.
14. Leite G.B., Abdelaziz A.E.M., Hallenbeck P.C. Algal biofuels: challenges and opportunities. Bioresour. Technol. 2013, 145:134-141.
15. Liang C., Cao S., Zhang X., Zhu B., Su Z., Xu D., Guang X., Ye N. De novo sequencing and global transcriptome analysis of Nannochloropsis sp. (Eustigmatophyceae) following nitrogen starvation. Bioenergy Res. 2013, 6:494-505.
16. Lin Q., Gu N., Li G., Lin J., Huang L., Tan L. Effects of inorganic carbon concentration on carbon formation, nitrate utilization, biomass and oil accumulation of Nannochloropsis oculata CS 179. Bioresour. Technol. 2012, 111:353-359.
17. Olofsson M., Lamela T., Nilsson E., Berge J.P., del Pino V., Uronen P., Legrand C. Seasonal variation of lipids and fatty acids of the microalgae Nannochloropsis oculata grown in outdoor large-scale photobioreactors. Energies 2012, 5:1577-1592.
18. Pal D., Khozin-Goldberg I., Cohen Z., Boussiba S. The effect of light, salinity, and nitrogen availability on lipid production by Nannochloropsis sp. Appl. Microbiol. Biotechnol. 2011, 90:1429-1441.
19. Quinn J.C., Yates T., Douglas N., Weyer K., Butler J., Bradley T.H., Lammers P.J. Nannochloropsis production metrics in a scalable outdoor photobioreactor for commercial applications. Bioresour. Technol. 2012, 117:164-171.
20. Radakovits R., Jinkerson R.E., Fuerstenberg S.I., Tae H., Settlage R.E., Boore J.L., Posewitz M.C. Draft genome sequence and genetic transformation of the oleaginous alga Nannochloropsis gaditana. Nat. Commun. 2012, 3:686.
21. Ren M., Ogden K. Cultivation of Nannochloropsis gaditana on mixtures of nitrogen sources. Environ. Prog. Sustain. Energy 2014, 33:551-555.
22. Ren M., Ogden K., Lian B. Effect of culture conditions on the growth rate and lipid production of microalgae Nannochloropsis gaditana. J. Renew. Sustain. Energy 2013, 5.
23. Sforza E., Bertucco A., Morosinotto T., Giacometti G.M. Photobioreactors for microalgal growth and oil production with Nannochloropsis salina: from lab-scale experiments to large-scale design. Chem. Eng. Res. Des. 2012, 90:1151-1158.
24. Silva C., Soliman E., Cameron G., Fabiano L.A., Seider W.D., Dunlop E.H., Coaldrake A.K. Commercial-scale biodiesel production from algae. Ind. Eng. Chem. Res. 2014, 53:5311-5324.
25. Simionato D., Block M.A., La Rocca N., Jouhet J., Marechal E., Finazzi G., Morosinotto T. The response of Nannochloropsis gaditana to nitrogen starvation includes de novo biosynthesis of triacylglycerols, a decrease of chloroplast galactolipids, and reorganization of the photosynthetic apparatus. Eukaryot. Cell 2013, 12:665-676.
26. Solovchenko A., Lukyanov A., Solovchenko O., Didi-Cohen S., Boussiba S., Khozin-Goldberg I. Interactive effects of salinity, high light, and nitrogen starvation on fatty acid and carotenoid profiles in Nannochloropsis oceanica CCALA 804. Eur. J. Lipid Sci. Technol. 2014, 116:635-644.
27. Tamburic B., Guruprasad S., Radford D.T., Szabo M., Lilley R.M., Larkum A.W.D., Franklin J.B., Kramer D.M., Blackburn S.I., Raven J.A., Schliep M., Ralph P.J. The effect of diel temperature and light cycles on the growth of Nannochloropsis oculata in a photobioreactor matrix. PLoS One 2014, 9(1).
28. Van Wagenen J., Miller T.W., Hobbs S., Hook P., Crowe B., Huesemann M. Effects of light and temperature on fatty acid production in Nannochloropsis salina. Energies 2012, 5:731-740.
29. Wahidin S., Idris A., Shaleh S.R.M. The influence of light intensity and photoperiod on the growth and lipid content of microalgae Nannochloropsis sp. Bioresour. Technol. 2013, 129:7-11.
30. Wang D., Ning K., Li J., Hu J., Han D., Wang H., Zeng X., Jing X., Zhou Q., Su X., Chang X., Wang A., Wang W., Jia J., Wei L., Xin Y., Qiao Y., Huang R., Chen J., Han B., Yoon K., Hill R.T., Zohar Y., Chen F., Hu Q., Xu J. Nannochloropsis genomes reveal evolution of microalgal oleaginous traits. PLoS Genet. 2014, 10(1). e1004094-e1004094.
31. Wei L., Huang X., Huang Z., Zhou Z. Orthogonal test design for optimization of lipid accumulation and lipid property in Nannochloropsis oculata for biodiesel production. Bioresour. Technol. 2013, 147:534-538.