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Volumn 28, Issue 2, 2015, Pages 91-99

miR-126 inhibits cell proliferation and induces cell apoptosis of hepatocellular carcinoma cells partially by targeting Sox2

Author keywords

Cell apoptosis; Cell cycle; Cell proliferation; Hepatocellular carcinoma; miR 126; Sox2

Indexed keywords

MICRORNA; MIRN126 MICRORNA, HUMAN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

EID: 84939966188     PISSN: 09147470     EISSN: 17490774     Source Type: Journal    
DOI: 10.1007/s13577-014-0105-z     Document Type: Article
Times cited : (54)

References (30)
  • 1
    • 77953776656 scopus 로고    scopus 로고
    • Future perspectives in hepatocellular carcinoma
    • PID: 2054731
    • Worns MA, Galle PR. Future perspectives in hepatocellular carcinoma. Dig Liver Dis. 2010;42(Suppl 3):S302–9. doi:10.1016/s1590-8658(10)60521-x.
    • (2010) Dig Liver Dis , vol.42 , pp. S302-S309
    • Worns, M.A.1    Galle, P.R.2
  • 2
    • 58849143425 scopus 로고    scopus 로고
    • The epidemiology of hepatocellular cancer: from the perspectives of public health problem to tumor biology
    • PID: 1914880
    • Caldwell S, Park SH. The epidemiology of hepatocellular cancer: from the perspectives of public health problem to tumor biology. J Gastroenterol. 2009;44(Suppl 19):96–101. doi:10.1007/s00535-008-2258-6.
    • (2009) J Gastroenterol , vol.44 , pp. 96-101
    • Caldwell, S.1    Park, S.H.2
  • 3
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • COI: 1:CAS:528:DC%2BD2cXhtVals7o%3D, PID: 1474443
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281–97.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 4
    • 33846283385 scopus 로고    scopus 로고
    • The evolution of gene regulation by transcription factors and microRNAs
    • COI: 1:CAS:528:DC%2BD2sXmt1OmsQ%3D%3D, PID: 1723019
    • Chen K, Rajewsky N. The evolution of gene regulation by transcription factors and microRNAs. Nat Rev Genet. 2007;8(2):93–103. doi:10.1038/nrg1990.
    • (2007) Nat Rev Genet , vol.8 , Issue.2 , pp. 93-103
    • Chen, K.1    Rajewsky, N.2
  • 5
    • 84861533055 scopus 로고    scopus 로고
    • microRNAs in cancer management
    • COI: 1:CAS:528:DC%2BC38XnvFOntbc%3D, PID: 2265223
    • Kong YW, Ferland-McCollough D, Jackson TJ, Bushell M. microRNAs in cancer management. Lancet Oncol. 2012;13(6):e249–58. doi:10.1016/s1470-2045(12)70073-6.
    • (2012) Lancet Oncol , vol.13 , Issue.6 , pp. e249-e258
    • Kong, Y.W.1    Ferland-McCollough, D.2    Jackson, T.J.3    Bushell, M.4
  • 6
    • 84885175599 scopus 로고    scopus 로고
    • Serum microRNA-1 and microRNA-122 are prognostic markers in patients with hepatocellular carcinoma. Eur J Cancer (Oxford
    • Koberle V, Kronenberger B, Pleli T, Trojan J, Imelmann E, Peveling-Oberhag J, et al. Serum microRNA-1 and microRNA-122 are prognostic markers in patients with hepatocellular carcinoma. Eur J Cancer (Oxford, England: 1990). 2013. doi:10.1016/j.ejca.2013.06.002.
    • (2013) England , pp. 1990
    • Koberle, V.1    Kronenberger, B.2    Pleli, T.3    Trojan, J.4    Imelmann, E.5    Peveling-Oberhag, J.6
  • 7
    • 84881224445 scopus 로고    scopus 로고
    • Meta-analysis of microRNA-183 family expression in human cancer studies comparing cancer tissues with noncancerous tissues
    • COI: 1:CAS:528:DC%2BC3sXhtFSqs7nN, PID: 2379165
    • Zhang QH, Sun HM, Zheng RZ, Li YC, Zhang Q, Cheng P, et al. Meta-analysis of microRNA-183 family expression in human cancer studies comparing cancer tissues with noncancerous tissues. Gene. 2013;527(1):26–32. doi:10.1016/j.gene.2013.06.006.
    • (2013) Gene , vol.527 , Issue.1 , pp. 26-32
    • Zhang, Q.H.1    Sun, H.M.2    Zheng, R.Z.3    Li, Y.C.4    Zhang, Q.5    Cheng, P.6
  • 8
    • 84891826425 scopus 로고    scopus 로고
    • Alterations of epigenetics and microRNA in hepatocellular carcinoma
    • Saito Y, Hibino S, Saito H. Alterations of epigenetics and microRNA in hepatocellular carcinoma. Hepatol Res. 2013;. doi:10.1111/hepr.12147.
    • (2013) Hepatol Res
    • Saito, Y.1    Hibino, S.2    Saito, H.3
  • 9
    • 77954527279 scopus 로고    scopus 로고
    • EGFL7 meets miRNA-126: an angiogenesis alliance
    • Nikolic I, Plate KH, Schmidt MH. EGFL7 meets miRNA-126: an angiogenesis alliance. J Angiogenesis Res. 2010;2(1):9. doi:10.1186/2040-2384-2-9.
    • (2010) J Angiogenesis Res , vol.2 , Issue.1 , pp. 9
    • Nikolic, I.1    Plate, K.H.2    Schmidt, M.H.3
  • 10
    • 40349103409 scopus 로고    scopus 로고
    • MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
    • COI: 1:CAS:528:DC%2BD1cXhvFCit7c%3D, PID: 1822751
    • Harris TA, Yamakuchi M, Ferlito M, Mendell JT, Lowenstein CJ. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci USA. 2008;105(5):1516–21. doi:10.1073/pnas.0707493105.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.5 , pp. 1516-1521
    • Harris, T.A.1    Yamakuchi, M.2    Ferlito, M.3    Mendell, J.T.4    Lowenstein, C.J.5
  • 11
    • 66049084202 scopus 로고    scopus 로고
    • MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo
    • Liu B, Peng XC, Zheng XL, Wang J, Qin YW. MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo. Lung Cancer (Amsterdam, Netherlands). 2009;66(2):169–75. doi:10.1016/j.lungcan.2009.01.010.
    • (2009) Lung Cancer (Amsterdam, Netherlands) , vol.66 , Issue.2 , pp. 169-175
    • Liu, B.1    Peng, X.C.2    Zheng, X.L.3    Wang, J.4    Qin, Y.W.5
  • 12
    • 46249125127 scopus 로고    scopus 로고
    • MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1
    • COI: 1:CAS:528:DC%2BD1cXps1Wltbg%3D, PID: 1855501
    • Wong QW, Lung RW, Law PT, Lai PB, Chan KY, To KF, et al. MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1. Gastroenterology. 2008;135(1):257–69. doi:10.1053/j.gastro.2008.04.003.
    • (2008) Gastroenterology , vol.135 , Issue.1 , pp. 257-269
    • Wong, Q.W.1    Lung, R.W.2    Law, P.T.3    Lai, P.B.4    Chan, K.Y.5    To, K.F.6
  • 13
    • 79551511687 scopus 로고    scopus 로고
    • MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis
    • COI: 1:CAS:528:DC%2BC3MXhslyiu70%3D, PID: 2130460
    • Otsubo T, Akiyama Y, Hashimoto Y, Shimada S, Goto K, Yuasa Y. MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis. PLoS One. 2011;6(1):e16617. doi:10.1371/journal.pone.0016617.
    • (2011) PLoS One , vol.6 , Issue.1 , pp. e16617
    • Otsubo, T.1    Akiyama, Y.2    Hashimoto, Y.3    Shimada, S.4    Goto, K.5    Yuasa, Y.6
  • 14
    • 84869002238 scopus 로고    scopus 로고
    • The functions of microRNAs in pluripotency and reprogramming
    • COI: 1:CAS:528:DC%2BC38Xhs1ajsbfF, PID: 2313191
    • Leonardo TR, Schultheisz HL, Loring JF, Laurent LC. The functions of microRNAs in pluripotency and reprogramming. Nat Cell Biol. 2012;14(11):1114–21. doi:10.1038/ncb2613.
    • (2012) Nat Cell Biol , vol.14 , Issue.11 , pp. 1114-1121
    • Leonardo, T.R.1    Schultheisz, H.L.2    Loring, J.F.3    Laurent, L.C.4
  • 16
    • 84894728095 scopus 로고    scopus 로고
    • MiR-494 within an oncogenic MicroRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of MCC. Hepatology (Baltimore
    • Lim L, Balakrishnan A, Huskey N, Jones KD, Jodari M, Ng R, et al. MiR-494 within an oncogenic MicroRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of MCC. Hepatology (Baltimore, MD). 2013. doi:10.1002/hep.26662.
    • (2013) MD)
    • Lim, L.1    Balakrishnan, A.2    Huskey, N.3    Jones, K.D.4    Jodari, M.5    Ng, R.6
  • 17
    • 84881478455 scopus 로고    scopus 로고
    • Let-7c inhibits A549 cell proliferation through oncogenic TRIB2 related factors
    • COI: 1:CAS:528:DC%2BC3sXhtFCqtrnP, PID: 2385089
    • Wang PY, Sun YX, Zhang S, Pang M, Zhang HH, Gao SY, et al. Let-7c inhibits A549 cell proliferation through oncogenic TRIB2 related factors. FEBS Lett. 2013;587(16):2675–81. doi:10.1016/j.febslet.2013.07.004.
    • (2013) FEBS Lett , vol.587 , Issue.16 , pp. 2675-2681
    • Wang, P.Y.1    Sun, Y.X.2    Zhang, S.3    Pang, M.4    Zhang, H.H.5    Gao, S.Y.6
  • 18
    • 84904747598 scopus 로고    scopus 로고
    • Involvement of miRNA-29a in epigenetic regulation of transforming growth factor-beta-induced epithelial–mesenchymal transition in hepatocellular carcinoma
    • Kogure T, Kondo Y, Kakazu E, Ninomiya M, Kimura O, Shimosegawa T. Involvement of miRNA-29a in epigenetic regulation of transforming growth factor-beta-induced epithelial–mesenchymal transition in hepatocellular carcinoma. Hepatol Res. 2013;. doi:10.1111/hepr.12188.
    • (2013) Hepatol Res
    • Kogure, T.1    Kondo, Y.2    Kakazu, E.3    Ninomiya, M.4    Kimura, O.5    Shimosegawa, T.6
  • 19
    • 84904260084 scopus 로고    scopus 로고
    • Crosstalk-induced loss of miR-126 promotes angiogenesis
    • PID: 2401322
    • de Giorgio A, Castellano L, Krell J, Stebbing J. Crosstalk-induced loss of miR-126 promotes angiogenesis. Oncogene. 2013;. doi:10.1038/onc.2013.317.
    • (2013) Oncogene
    • de Giorgio, A.1    Castellano, L.2    Krell, J.3    Stebbing, J.4
  • 20
    • 84874424011 scopus 로고    scopus 로고
    • The clinical and prognostic implications of pluripotent stem cell gene expression in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC3sXms1Kit7g%3D, PID: 2359975
    • Yin X, Li YW, Jin JJ, Zhou Y, Ren ZG, Qiu SJ, et al. The clinical and prognostic implications of pluripotent stem cell gene expression in hepatocellular carcinoma. Oncol Lett. 2013;5(4):1155–62. doi:10.3892/ol.2013.1151.
    • (2013) Oncol Lett , vol.5 , Issue.4 , pp. 1155-1162
    • Yin, X.1    Li, Y.W.2    Jin, J.J.3    Zhou, Y.4    Ren, Z.G.5    Qiu, S.J.6
  • 21
    • 79955860688 scopus 로고    scopus 로고
    • Role of Sox2 and Oct4 in predicting survival of hepatocellular carcinoma patients after hepatectomy
    • COI: 1:CAS:528:DC%2BC3MXmtFClsLs%3D, PID: 2137602
    • Huang P, Qiu J, Li B, Hong J, Lu C, Wang L, et al. Role of Sox2 and Oct4 in predicting survival of hepatocellular carcinoma patients after hepatectomy. Clin Biochem. 2011;44(8–9):582–9. doi:10.1016/j.clinbiochem.2011.02.012.
    • (2011) Clin Biochem , vol.44 , Issue.8-9 , pp. 582-589
    • Huang, P.1    Qiu, J.2    Li, B.3    Hong, J.4    Lu, C.5    Wang, L.6
  • 22
    • 0028808183 scopus 로고
    • Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3
    • COI: 1:CAS:528:DyaK2MXpt1OhtLk%3D, PID: 759024
    • Yuan H, Corbi N, Basilico C, Dailey L. Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev. 1995;9(21):2635–45.
    • (1995) Genes Dev , vol.9 , Issue.21 , pp. 2635-2645
    • Yuan, H.1    Corbi, N.2    Basilico, C.3    Dailey, L.4
  • 23
    • 0242353154 scopus 로고    scopus 로고
    • Vertebrate neurogenesis is counteracted by So1–3 activity
    • COI: 1:CAS:528:DC%2BD3sXosVOiur0%3D, PID: 1451754
    • Bylund M, Andersson E, Novitch BG, Muhr J. Vertebrate neurogenesis is counteracted by So1–3 activity. Nat Neurosci. 2003;6(11):1162–8. doi:10.1038/nn1131.
    • (2003) Nat Neurosci , vol.6 , Issue.11 , pp. 1162-1168
    • Bylund, M.1    Andersson, E.2    Novitch, B.G.3    Muhr, J.4
  • 24
    • 0033559518 scopus 로고    scopus 로고
    • From head to toes: the multiple facets of Sox proteins
    • COI: 1:CAS:528:DyaK1MXitFens7s%3D, PID: 1003780
    • Wegner M. From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res. 1999;27(6):1409–20.
    • (1999) Nucleic Acids Res , vol.27 , Issue.6 , pp. 1409-1420
    • Wegner, M.1
  • 25
    • 77952505658 scopus 로고    scopus 로고
    • SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas
    • PID: 2012641
    • Hussenet T, Dali S, Exinger J, Monga B, Jost B, Dembele D, et al. SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas. PLoS One. 2010;5(1):e8960. doi:10.1371/journal.pone.0008960.
    • (2010) PLoS One , vol.5 , Issue.1 , pp. e8960
    • Hussenet, T.1    Dali, S.2    Exinger, J.3    Monga, B.4    Jost, B.5    Dembele, D.6
  • 26
    • 71549155909 scopus 로고    scopus 로고
    • Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy
    • PID: 1965769
    • Saigusa S, Tanaka K, Toiyama Y, Yokoe T, Okugawa Y, Ioue Y, et al. Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. Ann Surg Oncol. 2009;16(12):3488–98. doi:10.1245/s10434-009-0617-z.
    • (2009) Ann Surg Oncol , vol.16 , Issue.12 , pp. 3488-3498
    • Saigusa, S.1    Tanaka, K.2    Toiyama, Y.3    Yokoe, T.4    Okugawa, Y.5    Ioue, Y.6
  • 27
    • 80051654241 scopus 로고    scopus 로고
    • SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell
    • COI: 1:CAS:528:DC%2BC3MXhtFCjtL%2FL, PID: 2141510
    • Jia X, Li X, Xu Y, Zhang S, Mou W, Liu Y, et al. SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell. J Mol Cell Biol. 2011;3(4):230–8. doi:10.1093/jmcb/mjr002.
    • (2011) J Mol Cell Biol , vol.3 , Issue.4 , pp. 230-238
    • Jia, X.1    Li, X.2    Xu, Y.3    Zhang, S.4    Mou, W.5    Liu, Y.6
  • 28
    • 84873951599 scopus 로고    scopus 로고
    • Sox2 expression predicts poor survival of hepatocellular carcinoma patients and it promotes liver cancer cell invasion by activating Slug
    • Sun C, Sun L, Li Y, Kang X, Zhang S, Liu Y. Sox2 expression predicts poor survival of hepatocellular carcinoma patients and it promotes liver cancer cell invasion by activating Slug. Med Oncol (Northwood, London, England). 2013;30(2):503. doi:10.1007/s12032-013-0503-1.
    • (2013) Med Oncol (Northwood, London, England) , vol.30 , Issue.2 , pp. 503
    • Sun, C.1    Sun, L.2    Li, Y.3    Kang, X.4    Zhang, S.5    Liu, Y.6
  • 29
    • 84859846404 scopus 로고    scopus 로고
    • Sox2 targets cyclinE, p27 and survivin to regulate androgen-independent human prostate cancer cell proliferation and apoptosis
    • COI: 1:CAS:528:DC%2BC38XpsVKntb0%3D, PID: 2246903
    • Lin F, Lin P, Zhao D, Chen Y, Xiao L, Qin W, et al. Sox2 targets cyclinE, p27 and survivin to regulate androgen-independent human prostate cancer cell proliferation and apoptosis. Cell Prolif. 2012;45(3):207–16. doi:10.1111/j.1365-2184.2012.00812.x.
    • (2012) Cell Prolif , vol.45 , Issue.3 , pp. 207-216
    • Lin, F.1    Lin, P.2    Zhao, D.3    Chen, Y.4    Xiao, L.5    Qin, W.6
  • 30
    • 84884990982 scopus 로고    scopus 로고
    • [miR-126 inhibits colon cancer proliferation and invasion through targeting IRS1, SLC7A5 and TOM1 gene]
    • COI: 1:CAS:528:DC%2BC2cXitVGltA%3D%3
    • Li N, Li X, Huang S, Shen S, Wang X. [miR-126 inhibits colon cancer proliferation and invasion through targeting IRS1, SLC7A5 and TOM1 gene]. Zhong nan da xue xue bao Yi xue ban = J Cent South Univ Med Sci. 2013;38(8):809–17. doi:10.3969/j.issn.1672-7347.08.009.
    • (2013) Zhong nan da xue xue bao Yi xue ban = J Cent South Univ Med Sci , vol.38 , Issue.8 , pp. 809-817
    • Li, N.1    Li, X.2    Huang, S.3    Shen, S.4    Wang, X.5


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