M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator

Acta Neuropathologica

Volumn 129, Issue 5, 2015, Pages 653-667

  Bahia El Idrissi, Nawal ^a   Das, Pranab K ^a,b,c   Fluiter, Kees ^a   Rosa, Patricia S ^c   Vreijling, Jeroen ^a   Troost, Dirk ^a   Morgan, B Paul ^d   Baas, Frank ^a   Ramaglia, Valeria ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c INSTITUTO LAURO DE SOUZA LIMA   (Brazil)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Complement; Leprosy; Neuropathy; Therapy

Indexed keywords

COMPLEMENT MEMBRANE ATTACK COMPLEX; LIPOARABINOMANNAN; LIPOPOLYSACCHARIDE;

ANIMAL; AXON; BIOPSY; CHEMISTRY; COMPLEMENT ACTIVATION; DRUG EFFECTS; FEMALE; HUMAN; IMMUNOLOGY; LEPROSY; METABOLISM; MICROBIOLOGY; MOUSE; MYCOBACTERIUM LEPRAE; MYELIN SHEATH; NERVOUS SYSTEM INJURY; OUTBRED STRAIN; PATHOGENICITY; PATHOLOGY;

ANIMALS; ANIMALS, OUTBRED STRAINS; AXONS; BIOPSY; COMPLEMENT ACTIVATION; COMPLEMENT MEMBRANE ATTACK COMPLEX; FEMALE; HUMANS; LEPROSY; LIPOPOLYSACCHARIDES; MICE; MYCOBACTERIUM LEPRAE; MYELIN SHEATH; TRAUMA, NERVOUS SYSTEM;

EID: 84939937973     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-015-1404-5     Document Type: Article

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