Association between Plasma Levels of Macrophage Inhibitory Cytokine-1 before Diagnosis of Colorectal Cancer and Mortality

Gastroenterology

Volumn 149, Issue 3, 2015, Pages 614-622

  Mehta, Raaj S ^a,b   Chong, Dawn Q ^a,b,c   Song, Mingyang ^a,b,d   Meyerhardt, Jeffrey A ^b,e   Ng, Kimmie ^b,e   Nishihara, Reiko ^b,d,e   Qian, Zhirong ^b,e   Morikawa, Teppei ^b,e   Wu, Kana ^d   Giovannucci, Edward L ^d,f   Fuchs, Charles S ^b,e,f   Ogino, Shuji ^b,d,e,f   Chan, Andrew T ^a,b,f  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Colon Cancer Risk Factor; Cyclooxygenase; GDF15; Immunity

Indexed keywords

C REACTIVE PROTEIN; CYCLOOXYGENASE 2; GROWTH DIFFERENTIATION FACTOR 15; INTERLEUKIN 6; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE 2; UNCLASSIFIED DRUG; AUTACOID; GDF15 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; TUMOR MARKER;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CANCER DIAGNOSIS; CANCER MORTALITY; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RISK FACTOR; BLOOD; COLORECTAL NEOPLASMS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RISK ASSESSMENT; TIME FACTOR; UPREGULATION; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS, TUMOR; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; UP-REGULATION;

EID: 84939824714     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.05.038     Document Type: Article

References (29)

1. D. Wang, and R.N. DuBois The role of COX-2 in Intestinal Inflammation and colorectal cancer Oncogene 29 2010 781 788
2. A.T. Chan, S. Ogino, and C.S. Fuchs Aspirin and the risk of colorectal cancer in relation to the expression of COX-2 N Engl J Med 356 2007 2131 2142
3. A.T. Chan, S. Ogino, and C.S. Fuchs Aspirin use and survival after diagnosis of colorectal cancer JAMA 302 2009 649 658
4. X. Wang, S.J. Baek, and T.E. Eling The diverse roles of nonsteroidal anti-inflammatory drug activated gene (NAG-1/GDF15) in cancer Biochem Pharmacol 85 2013 597 606
5. X. Wang, P.J. Kingsley, L.J. Marnett, and et al. The role of NAG-1/GDF15 in the inhibition of intestinal polyps in APC/Min mice by sulindac Cancer Prev Res 4 2011 150 160
6. S.J. Baek, R. Okazaki, S.-H. Lee, and et al. Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia Gastroenterology 131 2006 1553 1560
7. S.N. Breit, H. Johnen, A.D. Cook, and et al. The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism Growth Factors 29 2011 187 195
8. T.A. Zimmers, J.C. Gutierrez, and L.G. Koniaris Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer J Cancer Res Clin Oncol 136 2010 571 576
9. R.S. Mehta, M. Song, N. Bezawada, and et al. A prospective study of macrophage inhibitory cytokine-1 (MIC-1/GDF15) and risk of colorectal cancer J Natl Cancer Inst 106 2014 dju016
10. J. Koopmann, P. Buckhaults, D.A. Brown, and et al. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers Clin Cancer Res 10 2004 2386 2392
11. S. Shnaper, I. Desbaillets, D.A. Brown, and et al. Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome Int J Cancer 125 2009 2624 2630
12. A. Staff, A. Bock, C. Becker, and et al. Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer Gynecol Oncol 118 2010 237 243
13. D.A. Brown, K.W. Hance, C.J. Rogers, and et al. Serum macrophage inhibitory cytokine-1 (MIC-1/GDF15): a potential screening tool for the prevention of colon cancer? Cancer Epidemiol Biomarkers Prev 21 2012 337 346
14. D.A. Brown, R.L. Ward, P. Buckhaults, and et al. MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma Clin Cancer Res 9 2003 2642 2650
15. D.A. Brown, F. Lindmark, P. Stattin, and et al. Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer Clin Cancer Res 15 2009 6658 6664
16. S.E. Hankinson, W.C. Willett, J.E. Manson, and et al. Alcohol, height, and adiposity in relation to estrogen and prolactin levels in postmenopausal women J Natl Cancer Inst 87 1995 1297 1302
17. E.K. Wei, J. Ma, M.N. Pollak, and et al. C-peptide, insulin-like growth factor binding protein-1, glycosylated hemoglobin, and the risk of distal colorectal adenoma in women Cancer Epidemiol Biomar Prev 15 2006 750 755
18. E.K. Wei, E. Giovannucci, C.S. Fuchs, and et al. Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study J Natl Cancer Inst 97 2005 1688 1694
19. A.T. Chan, S. Ogino, E.L. Giovannucci, and et al. Inflammatory markers are associated with risk of colorectal cancer and chemopreventive response to anti-inflammatory drugs Gastroenterology 140 2011 799 808
20. S. Ogino, M. Brahmandam, T. Kawasaki, and et al. Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer Neoplasia 6 2006 458 464
21. W.G. Cochran The combination of estimates from different experiments Biometrics 10 1954 101 129
22. D.G. Kleinbaum, and M. Klein Survival Analysis: A Self-Learning Text 3rd ed. 2010 Springer London 585 588
23. M. Mimeault, and S.K. Batra Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer J Cell Physiol 224 2010 626 635
24. S.H. Park, H.J. Choi, H. Yang, and et al. Two in-and-out modulation strategies for endoplasmic reticulum stress-linked gene expression of pro-apoptotic macrophage-inhibitory cytokine 1 J Biol Chem 287 2012 19841 19855
25. K.K. Kim, J.J. Lee, Y. Yang, and et al. Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells Carcinogenesis 29 2008 704 712
26. H. Johnen, S. Lin, T. Kuffner, and et al. Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1 Nat Med 13 2007 1333 1340
27. M. Yamauchi, P. Lochhead, Y. Imamura, A. Kuchiba, and et al. Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer Cancer Epidemiol Biomarkers Prev 22 2013 1142 1152
28. S. Ogino, A.T. Chan, C.S. Fuchs, and E. Giovannucci Molecular pathologic epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field Gut 60 2011 397 411
29. J.A. Meyerhardt, and R.J. Mayer Systemic therapy for colorectal cancer N Engl J Med 352 2005 476 487