메뉴 건너뛰기




Volumn 8, Issue , 2015, Pages 2045-2051

Nivolumab in the treatment of malignant melanoma: Review of the literature

Author keywords

Monoclonal antibody; PD 1; PD L1

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBOPLATIN; DACARBAZINE; IPILIMUMAB; MELANOMA VACCINE; NIVOLUMAB; PACLITAXEL; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; PROGRAMMED DEATH 1 RECEPTOR; THYROTROPIN;

EID: 84939805890     PISSN: 11786930     EISSN: 11786930     Source Type: Journal    
DOI: 10.2147/OTT.S62102     Document Type: Review
Times cited : (33)

References (38)
  • 1
    • 84904628107 scopus 로고    scopus 로고
    • Nivolumab: A review of its use in patients with malignant melanoma
    • Deeks ED. Nivolumab: a review of its use in patients with malignant melanoma. Drugs. 2014;74(11):1233-1239.
    • (2014) Drugs , vol.74 , Issue.11 , pp. 1233-1239
    • Deeks, E.D.1
  • 4
    • 84255197842 scopus 로고    scopus 로고
    • Cancer immunotherapy comes of age
    • Mellman I, Coukos G, Dranoff G. Cancer immunotherapy comes of age. Nature. 2011;480(7378):480-489.
    • (2011) Nature , vol.480 , Issue.7378 , pp. 480-489
    • Mellman, I.1    Coukos, G.2    Dranoff, G.3
  • 5
    • 84887862839 scopus 로고    scopus 로고
    • A rheostat for immune responses: The unique properties of PD-1 and their advantages for clinical application
    • Okazaki T, Chikuma S, Iwai Y, Fagarasan S, Honjo T. A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application. Nat Immunol. 2013;14(12):1212-1218.
    • (2013) Nat Immunol , vol.14 , Issue.12 , pp. 1212-1218
    • Okazaki, T.1    Chikuma, S.2    Iwai, Y.3    Fagarasan, S.4    Honjo, T.5
  • 7
    • 0026700235 scopus 로고
    • Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
    • Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J. 1992;11(11):3887-3895.
    • (1992) EMBO J , vol.11 , Issue.11 , pp. 3887-3895
    • Ishida, Y.1    Agata, Y.2    Shibahara, K.3    Honjo, T.4
  • 8
    • 34547794178 scopus 로고    scopus 로고
    • PD-1 and PD-1 ligands: From discovery to clinical application
    • Okazaki T, Honjo T. PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol. 2007;19(7):813-824.
    • (2007) Int Immunol , vol.19 , Issue.7 , pp. 813-824
    • Okazaki, T.1    Honjo, T.2
  • 9
    • 0035923535 scopus 로고    scopus 로고
    • PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
    • Okazaki T, Maeda A, Nishimura H, Kurosaki T, Honjo T. PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine. Proc Natl Acad Sci U S A. 2001;98(24):13866-13871.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.24 , pp. 13866-13871
    • Okazaki, T.1    Maeda, A.2    Nishimura, H.3    Kurosaki, T.4    Honjo, T.5
  • 10
    • 0031685190 scopus 로고    scopus 로고
    • Immunological studies on PD-1 deficient mice: Implication of PD-1 as a negative regulator for B cell responses
    • Nishimura H, Minato N, Nakano T, Honjo T. Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. Int Immunol. 1998;10(10):1563-1572.
    • (1998) Int Immunol , vol.10 , Issue.10 , pp. 1563-1572
    • Nishimura, H.1    Minato, N.2    Nakano, T.3    Honjo, T.4
  • 11
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encod-ing an ITIM motif-carrying immunoreceptor
    • Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encod-ing an ITIM motif-carrying immunoreceptor. Immunity. 1999;11(2): 141-151.
    • (1999) Immunity , vol.11 , Issue.2 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 12
    • 0035846991 scopus 로고    scopus 로고
    • Autoimmune dilated cardio-myopathy in PD-1 receptor-deficient mice
    • Nishimura H, Okazaki T, Tanaka Y, et al. Autoimmune dilated cardio-myopathy in PD-1 receptor-deficient mice. Science. 2001;291(5502): 319-322.
    • (2001) Science , vol.291 , Issue.5502 , pp. 319-322
    • Nishimura, H.1    Okazaki, T.2    Tanaka, Y.3
  • 13
    • 10344220548 scopus 로고    scopus 로고
    • Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target
    • Thompson RH, Gillett MD, Cheville JC, et al. Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. Proc Natl Acad Sci U S A. 2004;101(49): 17174-17179.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.49 , pp. 17174-17179
    • Thompson, R.H.1    Gillett, M.D.2    Cheville, J.C.3
  • 14
    • 20244384862 scopus 로고    scopus 로고
    • Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer
    • Ohigashi Y, Sho M, Yamada Y, et al. Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer. Clin Cancer Res. 2005;11(8):2947-2953.
    • (2005) Clin Cancer Res , vol.11 , Issue.8 , pp. 2947-2953
    • Ohigashi, Y.1    Sho, M.2    Yamada, Y.3
  • 15
    • 33745491116 scopus 로고    scopus 로고
    • Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance
    • Wu C, Zhu Y, Jiang J, Zhao J, Zhang XG, Xu N. Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance. Acta Histochem. 2006;108(1): 19-24.
    • (2006) Acta Histochem , vol.108 , Issue.1 , pp. 19-24
    • Wu, C.1    Zhu, Y.2    Jiang, J.3    Zhao, J.4    Zhang, X.G.5    Xu, N.6
  • 16
    • 33847611968 scopus 로고    scopus 로고
    • Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer
    • Hamanishi J, Mandai M, Iwasaki M, et al. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer. Proc Natl Acad Sci U S A. 2007;104(9): 3360-3365.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.9 , pp. 3360-3365
    • Hamanishi, J.1    Mandai, M.2    Iwasaki, M.3
  • 17
    • 34248586083 scopus 로고    scopus 로고
    • Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers
    • Nakanishi J, Wada Y, Matsumoto K, Azuma M, Kikuchi K, Ueda S. Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers. Cancer Immunol Immunother. 2007;56(8):1173-1182.
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.8 , pp. 1173-1182
    • Nakanishi, J.1    Wada, Y.2    Matsumoto, K.3    Azuma, M.4    Kikuchi, K.5    Ueda, S.6
  • 18
    • 34247532726 scopus 로고    scopus 로고
    • Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer
    • Nomi T, Sho M, Akahori T, et al. Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer. Clin Cancer Res. 2007;13(7):2151-2157.
    • (2007) Clin Cancer Res , vol.13 , Issue.7 , pp. 2151-2157
    • Nomi, T.1    Sho, M.2    Akahori, T.3
  • 19
    • 77950283280 scopus 로고    scopus 로고
    • Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma
    • Hino R, Kabashima K, Kato Y, et al. Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. Cancer. 2010;116(7):1757-1766.
    • (2010) Cancer , vol.116 , Issue.7 , pp. 1757-1766
    • Hino, R.1    Kabashima, K.2    Kato, Y.3
  • 20
    • 84927613720 scopus 로고    scopus 로고
    • PD-L1 marks a subset of melanomas with a shorter overall survival and distinct genetic and morphological characteristics
    • Massi D, Brusa D, Merelli B, et al. PD-L1 marks a subset of melanomas with a shorter overall survival and distinct genetic and morphological characteristics. Ann Oncol. 2014;25(12):2433-2442.
    • (2014) Ann Oncol , vol.25 , Issue.12 , pp. 2433-2442
    • Massi, D.1    Brusa, D.2    Merelli, B.3
  • 21
    • 34250177269 scopus 로고    scopus 로고
    • PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
    • Thompson RH, Dong H, Lohse CM, et al. PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res. 2007;13(6):1757-1761.
    • (2007) Clin Cancer Res , vol.13 , Issue.6 , pp. 1757-1761
    • Thompson, R.H.1    Dong, H.2    Lohse, C.M.3
  • 22
    • 84879795618 scopus 로고    scopus 로고
    • The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer
    • Muenst S, Soysal SD, Gao F, Obermann EC, Oertli D, Gillanders WE. The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer. Breast Cancer Res Treat. 2013;139(3):667-676.
    • (2013) Breast Cancer Res Treat , vol.139 , Issue.3 , pp. 667-676
    • Muenst, S.1    Soysal, S.D.2    Gao, F.3    Obermann, E.C.4    Oertli, D.5    Gillanders, W.E.6
  • 23
    • 13844294372 scopus 로고    scopus 로고
    • PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells
    • Iwai Y, Terawaki S, Honjo T. PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells. Int Immunol. 2005;17(2):133-144.
    • (2005) Int Immunol , vol.17 , Issue.2 , pp. 133-144
    • Iwai, Y.1    Terawaki, S.2    Honjo, T.3
  • 24
    • 0037126021 scopus 로고    scopus 로고
    • Involve-ment of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involve-ment of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A. 2002;99(19):12293-12297.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.19 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 25
    • 34848900497 scopus 로고    scopus 로고
    • Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs
    • Wong RM, Scotland RR, Lau RL, et al. Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs. Int Immunol. 2007;19(10):1223-1234.
    • (2007) Int Immunol , vol.19 , Issue.10 , pp. 1223-1234
    • Wong, R.M.1    Scotland, R.R.2    Lau, R.L.3
  • 26
    • 84901602398 scopus 로고    scopus 로고
    • Nivolumab: Promising survival signal coupled with limited toxicity raises expectations
    • O’Sullivan Coyne G, Madan RA, Gulley JL. Nivolumab: promising survival signal coupled with limited toxicity raises expectations. J Clin Oncol. 2014;32(10):986-988.
    • (2014) J Clin Oncol , vol.32 , Issue.10 , pp. 986-988
    • O’Sullivan Coyne, G.1    Madan, R.A.2    Gulley, J.L.3
  • 27
    • 84893489025 scopus 로고    scopus 로고
    • PD-1 as a potential target in cancer therapy
    • McDermott DF, Atkins MB. PD-1 as a potential target in cancer therapy. Cancer Med. 2013;2(5):662-673.
    • (2013) Cancer Med , vol.2 , Issue.5 , pp. 662-673
    • McDermott, D.F.1    Atkins, M.B.2
  • 28
    • 77954899030 scopus 로고    scopus 로고
    • Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
    • Brahmer JR, Drake CG, Wollner I, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28(19):3167-3175.
    • (2010) J Clin Oncol , vol.28 , Issue.19 , pp. 3167-3175
    • Brahmer, J.R.1    Drake, C.G.2    Wollner, I.3
  • 29
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26): 2443-2454.
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 30
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O’Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711-723.
    • (2010) N Engl J Med , vol.363 , Issue.8 , pp. 711-723
    • Hodi, F.S.1    O’Day, S.J.2    McDermott, D.F.3
  • 31
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med. 2011;364(26):2517-2526.
    • (2011) N Engl J Med , vol.364 , Issue.26 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3
  • 32
    • 84879777241 scopus 로고    scopus 로고
    • Nivolumab plus ipilimumab in advanced melanoma
    • Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. 2013;369(2):122-133.
    • (2013) N Engl J Med , vol.369 , Issue.2 , pp. 122-133
    • Wolchok, J.D.1    Kluger, H.2    Callahan, M.K.3
  • 33
    • 84929481482 scopus 로고    scopus 로고
    • Nivolumab and ipilimumab versus ipilimumab in untreated melanoma
    • Postow MA, Chesney J, Pavlick AC, et al. Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. N Engl J Med. 2015;372(21): 2006-2017.
    • (2015) N Engl J Med , vol.372 , Issue.21 , pp. 2006-2017
    • Postow, M.A.1    Chesney, J.2    Pavlick, A.C.3
  • 34
    • 84892866206 scopus 로고    scopus 로고
    • Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or -naïve melanoma
    • Weber JS, Kudchadkar RR, Yu B, et al. Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or -naïve melanoma. J Clin Oncol. 2013;31(34):4311-4318.
    • (2013) J Clin Oncol , vol.31 , Issue.34 , pp. 4311-4318
    • Weber, J.S.1    Kudchadkar, R.R.2    Yu, B.3
  • 35
    • 84898973055 scopus 로고    scopus 로고
    • Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
    • Topalian SL, Sznol M, McDermott DF, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol. 2014;32(10):1020-1030.
    • (2014) J Clin Oncol , vol.32 , Issue.10 , pp. 1020-1030
    • Topalian, S.L.1    Sznol, M.2    McDermott, D.F.3
  • 36
    • 84925222119 scopus 로고    scopus 로고
    • Nivolumab in previously untreated melanoma without BRAF mutation
    • Robert C, Long GV, Brady B, et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med. 2015;372(4): 320-330.
    • (2015) N Engl J Med , vol.372 , Issue.4 , pp. 320-330
    • Robert, C.1    Long, G.V.2    Brady, B.3
  • 37
    • 84931083080 scopus 로고    scopus 로고
    • Nivolumab versus chemo-therapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomized, controlled, open-label, phase 3 trial
    • Weber JS, D’Angelo SP, Minor D, et al. Nivolumab versus chemo-therapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomized, controlled, open-label, phase 3 trial. Lancet Oncol. 2015;16(4):375-384.
    • (2015) Lancet Oncol , vol.16 , Issue.4 , pp. 375-384
    • Weber, J.S.1    D’Angelo, S.P.2    Minor, D.3
  • 38
    • 84929411847 scopus 로고    scopus 로고
    • Clinical applications of PD-1-based therapy: A focus on pembrolizumab (MK-3475) in the management of melanoma and other tumor types
    • Gangadhar TC, Salama AKS. Clinical applications of PD-1-based therapy: a focus on pembrolizumab (MK-3475) in the management of melanoma and other tumor types. Onco Targets Ther. 2015;8:929-937
    • (2015) Onco Targets Ther , vol.8 , pp. 929-937
    • Gangadhar, T.C.1    Salama, A.K.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.