-
1
-
-
33646852746
-
The prevalence of hepatitis C virus infection in the United States, 1999 through 2002
-
Armstrong GL, et al. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Inter Med 2006; 144:705–714.
-
(2006)
Ann Inter Med
, vol.144
, pp. 705-714
-
-
Armstrong, GL1
-
2
-
-
34250679750
-
Epidemiology of hepatitis C virus infection
-
Alter MJ. Epidemiology of hepatitis C virus infection. World J Gastroenterol 2007; 13:2436–2441.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 2436-2441
-
-
Alter, MJ.1
-
3
-
-
23944506014
-
Global epidemiology of hepatitis C virus infection
-
Shepard CW, Finelli L, Alter MJ. Global epidemiology of hepatitis C virus infection. Lancet Infect Dis 2005; 5:558–567.
-
(2005)
Lancet Infect Dis
, vol.5
, pp. 558-567
-
-
Shepard, CW1
Finelli, L2
Alter, MJ.3
-
4
-
-
84877280092
-
Evolving frequency and outcomes of liver transplantation based on etiology of liver disease
-
Singal AK, et al. Evolving frequency and outcomes of liver transplantation based on etiology of liver disease. Transplantation 2013; 95:755–760.
-
(2013)
Transplantation
, vol.95
, pp. 755-760
-
-
Singal, AK1
-
5
-
-
0029999878
-
Distribution of hepatitis C virus genotypes determined by line probe assay in patients with chronic hepatitis C seen at tertiary referral centers in the United States
-
Lau JYN, et al. Distribution of hepatitis C virus genotypes determined by line probe assay in patients with chronic hepatitis C seen at tertiary referral centers in the United States. Ann Inter Med 1996; 124:868–876.
-
(1996)
Ann Inter Med
, vol.124
, pp. 868-876
-
-
Lau, JYN1
-
6
-
-
0028945033
-
Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes
-
Bukh J, Miller RH, Purcell RH. Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes. Semin Liver Dis 1995; 15:41–63.
-
(1995)
Semin Liver Dis
, vol.15
, pp. 41-63
-
-
Bukh, J1
Miller, RH2
Purcell, RH.3
-
7
-
-
0036829816
-
Natural history of chronic hepatitis C
-
Seeff LB. Natural history of chronic hepatitis C. Hepatology 2002; 36:S35–S46.
-
(2002)
Hepatology
, vol.36
, pp. S35-S46
-
-
Seeff, LB.1
-
8
-
-
84897373608
-
Benefit–risk assessment of new and emerging treatments for & hepatitis C: focus on simeprevir and sofosbuvir
-
Gaetano JN. Benefit–risk assessment of new and emerging treatments for & hepatitis C: focus on simeprevir and sofosbuvir. Drug Healthc Patient Saf 2014; 6:37–45.
-
(2014)
Drug Healthc Patient Saf
, vol.6
, pp. 37-45
-
-
Gaetano, JN.1
-
9
-
-
79953176289
-
Boceprevir for previously treated chronic HCV genotype 1 infection
-
Bacon BR, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364:1207–1217.
-
(2011)
N Engl J Med
, vol.364
, pp. 1207-1217
-
-
Bacon, BR1
-
10
-
-
68249154875
-
Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection
-
McHutchison JG, et al. Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection. N Engl J Med 2009; 361:580–593.
-
(2009)
N Engl J Med
, vol.361
, pp. 580-593
-
-
McHutchison, JG1
-
11
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
Poordad F, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364:1195–1206.
-
(2011)
N Engl J Med
, vol.364
, pp. 1195-1206
-
-
Poordad, F1
-
12
-
-
77956268467
-
Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial
-
Kwo PY, et al. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial. Lancet 2010; 376:705–716.
-
(2010)
Lancet
, vol.376
, pp. 705-716
-
-
Kwo, PY1
-
13
-
-
84859955001
-
Review and management of drug interactions with boceprevir and telaprevir
-
Kiser JJ, et al. Review and management of drug interactions with boceprevir and telaprevir. Hepatology 2012; 55:1620–1628.
-
(2012)
Hepatology
, vol.55
, pp. 1620-1628
-
-
Kiser, JJ1
-
15
-
-
84921409702
-
Simeprevir for the treatment of hepatitis C virus infection
-
Reviews pharmacokinetics of simeprevir
-
Izquierdo L, et al. Simeprevir for the treatment of hepatitis C virus infection. & Pharmacogenomics Per Med 2014; 7:241–249. Reviews pharmacokinetics of simeprevir.
-
(2014)
& Pharmacogenomics Per Med
, vol.7
, pp. 241-249
-
-
Izquierdo, L1
-
16
-
-
84887865879
-
Simeprevir for the treatment of chronic hepatitis C
-
You DM, Pockros PJ. Simeprevir for the treatment of chronic hepatitis C. Expert Opin Pharmacother 2013; 14:2581–2589.
-
(2013)
Expert Opin Pharmacother
, vol.14
, pp. 2581-2589
-
-
You, DM1
Pockros, PJ.2
-
17
-
-
79960390342
-
Distinct functions of NS5A in hepatitis C virus RNA replication uncovered by studies with the NS5A inhibitor BMS-790052
-
Fridell RA, et al. Distinct functions of NS5A in hepatitis C virus RNA replication uncovered by studies with the NS5A inhibitor BMS-790052. J Virol 2011; 85:7312–7320.
-
(2011)
J Virol
, vol.85
, pp. 7312-7320
-
-
Fridell, RA1
-
18
-
-
84870441080
-
Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein
-
Belda O, Targett-Adams P. Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein. Virus Res 2012; 170:1–14.
-
(2012)
Virus Res
, vol.170
, pp. 1-14
-
-
Belda, O1
Targett-Adams, P.2
-
19
-
-
79955532870
-
The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A nonstructural viral protein
-
Lee C, et al. The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A nonstructural viral protein. Virology 2011; 414:10–18.
-
(2011)
Virology
, vol.414
, pp. 10-18
-
-
Lee, C1
-
20
-
-
77952035218
-
Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
-
Gao M, et al. Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect. Nature 2010; 465:96–100.
-
(2010)
Nature
, vol.465
, pp. 96-100
-
-
Gao, M1
-
21
-
-
84906811945
-
Daclatasvirþ asunaprevir: first global approval
-
Discusses the important aspects of pharmacokinetics and metabolism of this regimen
-
Poole RM. Daclatasvirþ asunaprevir: first global approval. Drugs 2014; & 74:1559–1571. Discusses the important aspects of pharmacokinetics and metabolism of this regimen.
-
(2014)
Drugs
, vol.74
, pp. 1559-1571
-
-
Poole, RM.1
-
22
-
-
84878475234
-
Sofosbuvir and daclatasvir combination therapy in a liver transplant recipient with severe recurrent cholestatic hepatitis C
-
Fontana R, et al. Sofosbuvir and daclatasvir combination therapy in a liver transplant recipient with severe recurrent cholestatic hepatitis C. Am J Transplant 2013; 13:1601–1605.
-
(2013)
Am J Transplant
, vol.13
, pp. 1601-1605
-
-
Fontana, R1
-
23
-
-
84938310727
-
Effect of food and acid reducing agents on the relative bioavailability and pharmacokinetics of ledipasvir/sofosbuvir fixed dose combination tablet [Abstract P_15]
-
19–21 May
-
German P YJ, West S, et al. Effect of food and acid reducing agents on the relative bioavailability and pharmacokinetics of ledipasvir/sofosbuvir fixed dose combination tablet [Abstract P_15]. In: 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy. 19–21 May 2014.
-
(2014)
15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy
-
-
German, P YJ1
West, S2
-
24
-
-
84896138890
-
Ledipasvir: a novel synthetic antiviral for the treatment of HCV & infection
-
Highlights some key pharmacokinetics of LDV
-
Gentile I, et al. Ledipasvir: a novel synthetic antiviral for the treatment of HCV & infection. Expert Opin Investig Drugs 2014; 23:561–571.. Highlights some key pharmacokinetics of LDV.
-
(2014)
Expert Opin Investig Drugs
, vol.23
, pp. 561-571
-
-
Gentile, I1
-
26
-
-
84922987262
-
Pharmacokinetics and safety of co-administered ABT-450 plus ritonavir (ABT 450/r), ABT-267 and ABT-333 as a single dose in subjects with normal hepatic function and in subjects with mild, moderate and severe hepatic impairment
-
[Abstract 758] 9–13 November Boston. Hepatology
-
Khatri A, Gaultier I, Menon R, et al. Pharmacokinetics and safety of co-administered ABT-450 plus ritonavir (ABT 450/r), ABT-267 and ABT-333 as a single dose in subjects with normal hepatic function and in subjects with mild, moderate and severe hepatic impairment. [Abstract 758]. In: 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); 9–13 November 2012; Boston. Hepatology vol. 56.
-
(2012)
63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
, vol.56
-
-
Khatri, A1
Gaultier, I2
Menon, R3
-
27
-
-
77958487999
-
New insights into structure and replication of the hepatitis C virus and clinical implications
-
Poenisch M, Bartenschlager R. New insights into structure and replication of the hepatitis C virus and clinical implications. Semin Liver Dis 2010; 30:333–347.
-
(2010)
Semin Liver Dis
, vol.30
, pp. 333-347
-
-
Poenisch, M1
Bartenschlager, R.2
-
28
-
-
33744465036
-
Allosteric inhibition of the hepatitis C virus NS5B RNA dependent RNA polymerase
-
Koch U, Narjes F. Allosteric inhibition of the hepatitis C virus NS5B RNA dependent RNA polymerase. Infect Disord Drug Targets 2006; 6:31–41.
-
(2006)
Infect Disord Drug Targets
, vol.6
, pp. 31-41
-
-
Koch, U1
Narjes, F.2
-
29
-
-
79959572824
-
Antiviral activity of the hepatitis C virus polymerase inhibitor filibuvir in genotype 1–infected patients
-
Wagner F, et al. Antiviral activity of the hepatitis C virus polymerase inhibitor filibuvir in genotype 1–infected patients. Hepatology 2011; 54: 50–59.
-
(2011)
Hepatology
, vol.54
, pp. 50-59
-
-
Wagner, F1
-
30
-
-
34547618419
-
Nonnucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections
-
Beaulieu PL. Nonnucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections. Curr Opin Investig Drugs 2007; 8:614–634.
-
(2007)
Curr Opin Investig Drugs
, vol.8
, pp. 614-634
-
-
Beaulieu, PL.1
-
31
-
-
84862696759
-
Rapid and strong antiviral activity of the nonnucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin
-
Larrey D, et al. Rapid and strong antiviral activity of the nonnucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin. J Hepatol 2012; 57:39–46.
-
(2012)
J Hepatol
, vol.57
, pp. 39-46
-
-
Larrey, D1
-
32
-
-
84923340638
-
Population pharmacokinetics of sofosbuvir and Its major metabolite (GS-331007) in healthy and HCV-Infected adult subjects. [Abstract]
-
1–4 November Washington, DC, USA. Hepatology
-
Kirby B, Gordi T, Symonds W, et al. Population pharmacokinetics of sofosbuvir and Its major metabolite (GS-331007) in healthy and HCV-Infected adult subjects. [Abstract]. In: 64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); 1–4 November 2013; Washington, DC, USA. Hepatology vol. 58.
-
(2013)
64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
, vol.58
-
-
Kirby, B1
Gordi, T2
Symonds, W3
-
34
-
-
84922879130
-
Sofosbuvir and ribavirin for treatment of compensated && recurrent hepatitis C virus infection after liver transplantation
-
Discusses the efficacy of SOF along with ribavirin in liver transplant patients and demonstrates th interactions with tacrolimus, mycophenolate, prednisone, cyclosporine, or azathioprine
-
Charlton M, et al. Sofosbuvir and ribavirin for treatment of compensated && recurrent hepatitis C virus infection after liver transplantation. Gastroenterology 2015; 148:108–117. Discusses the efficacy of SOF along with ribavirin in liver transplant patients and demonstrates the no interactions with tacrolimus, mycophenolate, prednisone, cyclosporine, or azathioprine.
-
(2015)
Gastroenterology
, vol.148
, pp. 108-117
-
-
Charlton, M1
-
35
-
-
84919360641
-
An interferon-free antiviral regimen for HCV after liver trans- && plantation
-
Describes why tacrolimus should be dosed weekly with the paritaprevir, ombitasvir, and dasabuvir with ribavirin regimen for genotype 1 hepatitis C in the post-transplant setting
-
Kwo PY, et al. An interferon-free antiviral regimen for HCV after liver trans- && plantation. N Engl J Med 2014; 371:2375–2382. Describes why tacrolimus should be dosed weekly with the paritaprevir, ombitasvir, and dasabuvir with ribavirin regimen for genotype 1 hepatitis C in the post-transplant setting.
-
(2014)
N Engl J Med
, vol.371
, pp. 2375-2382
-
-
Kwo, PY1
-
36
-
-
84870862182
-
Telaprevir-based triple therapy in liver transplant patients with hepatitis C virus: a 12-week pilot study providing safety and efficacy data
-
Werner CR, et al. Telaprevir-based triple therapy in liver transplant patients with hepatitis C virus: a 12-week pilot study providing safety and efficacy data. Liver Transpl 2012; 18:1464–1470.
-
(2012)
Liver Transpl
, vol.18
, pp. 1464-1470
-
-
Werner, CR1
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