Factors associated with early relapse to insulin dependence in unprovoked A-β + ketosis-prone diabetes

Journal of Diabetes and its Complications

Volumn 29, Issue 7, 2015, Pages 918-922

  Gaba, Ruchi ^a,b   Gambhire, Dhiraj ^c   Uy, Natalie ^a   Gonzalez, Erica V ^a,b   Iyer, Dinakar ^a   Hampe, Christiane S ^d   Ram, Nalini ^a,b   Balasubramanyam, Ashok ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b BEN TAUB GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Beta cell; HLA; Insulin dependence; Ketoacidosis; Multivariate

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ACARBOSE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; MEGLITINIDE; METFORMIN; PANCREAS ISLET CELL ANTIBODY; SITAGLIPTIN; GLUCOSE BLOOD LEVEL; HLA ANTIGEN;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL FEATURE; CONTROLLED STUDY; DIABETIC KETOACIDOSIS; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; INSULIN DEPENDENCE; INSULIN TREATMENT; KETOSIS PRONE DIABETES; MALE; PANCREAS ISLET CELL FUNCTION; PERSONAL EXPERIENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RELAPSE; REMISSION; RISK FACTOR; ANALYSIS; ANALYSIS OF VARIANCE; BLOOD; COMPARATIVE STUDY; COMPLICATION; DIABETES MELLITUS, TYPE 1; FACTUAL DATABASE; LONGITUDINAL STUDY; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; RECURRENT DISEASE; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL; TIME FACTOR;

ADULT; ANALYSIS OF VARIANCE; BLOOD GLUCOSE; DATABASES, FACTUAL; DIABETES MELLITUS, TYPE 1; DIABETIC KETOACIDOSIS; FEMALE; FOLLOW-UP STUDIES; HLA ANTIGENS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PROSPECTIVE STUDIES; RECURRENCE; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 84939575580     PISSN: 10568727     EISSN: 1873460X     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2015.04.013     Document Type: Article

References (14)

1. A. Balasubramanyam, G. Garza, L. Rodriguez, C.S. Hampe, L. Gaur, A. Lenmark, and et al. Accuracy and predictive value of classification schemes for ketosis-prone diabetes Diabetes Care 29 12 2006 2575 2579 (Pubmed: 17130187)
2. A. Balasubramanyam, R. Nalini, C.S. Hampe, and M. Maldonado Syndromes of ketosis-prone diabetes mellitus Endocrine Reviews 29 2008 292 302
3. M.A. Banerji, R.L. Chaiken, H. Huey, T. Tuomi, A.J. Norm, I.R. Mackay, and et al. GAD antibody negative NIDDM in adult black subjects with diabetic ketoacidosis and increased frequency of human leukocyte antigen DR3 and DR4. Flatbush diabetes Diabetes 43 1994 741 745 (PMID: 8194658)
4. B.M. Brooks-Worrell, D. Iyer, I. Coraza, C.S. Hampe, R. Nalini, K. Ozer, and et al. Islet-specific T-cell responses and proinflammatory monocytes define subtypes of autoantibody-negative ketosis-prone diabetes Diabetes Care 36 12 2013 4098 4103 10.2337/dc12-2328 (Epub 2013 Oct)
5. M. Maldonado, C.S. Hampe, L.K. Gaur, S. D'Amico, D. Iyer, L.P. Hammerle, and et al. Ketosis-prone diabetes: Dissection of a heterogeneous syndrome using an immunogenetic and beta cell functional classification, prospective analysis, and clinical outcomes Journal of Clinical Endocrinology and Metabolism 88 11 2003 5090 5098 (PubMed: 14602731)
6. F. Mauvais-Jarvis, E. Sobngwi, R. Porcher, J.P. Riveline, J.P. Kevorkian, C. Vaisse, and et al. Ketosis-prone type 2 diabetes in patients of sub-Saharan African origin: Clinical pathophysiology and natural history of beta-cell dysfunction and insulin resistance Diabetes 53 2004 645 653 (PMID: 14988248)
7. R. Nalini, L.K. Gaur, M. Maldonado, C.S. Hampe, L. Rodriguez, G. Garza, and et al. HLA class II alleles specify phenotypes of ketosis-prone diabetes Diabetes Care 31 2008 1195 1200 (PubMed: 18316396)
8. R. Nalini, K. Ozer, M. Maldanado, S. Patel, C.S. Hampe, A. Guthikonda, and et al. Presence or absence of a known DKA precipitant defines distinct syndromes of A-β + KPD based on long term beta cell function, HLA class II alleles, and gender predilection Metabolism 59 10 2010 1448 1455 10.1016/j.metabol.2010.01.009
9. S.G. Patel, J.W. Hsu, F. Jahoor, I. Coraza, J.R. Bain, R.D. Stevens, and et al. Pathogenesis of ketosis-prone diabetes Diabetes 62 3 2013 912 922 10.23337/db12-0624 (Epub 2012 Nov 16)
10. A. Pinero-Pilona, and P. Raskin Idiopathic type 1 diabetes Journal of Diabetes and its Complications 15 2001 328 335 (PMID: 11711327)
11. E. Sobngwi, and J.F. Gautier Adult-onset idiopathic type I or ketosis-prone type II diabetes: Evidence to revisit diabetes classification Diabetologia 45 2 2002 283 285
12. E. Sobngwi, F. Mauvais-Jarvis, P. Vexiau, J.C. Mbanya, and J.F. Gautier Diabetes in Africans. Part 2: Ketosis-prone atypical diabetes mellitus Diabetes & Metabolism 28 2002 5 12 (PMID: 11938022)
13. G.E. Umpierrez, D. Smiley, and A.E. Kitabchi Narrative review: Ketosis-prone type 2 diabetes mellitus Annals of Internal Medicine 144 5 2006 350 357 (PubMed: 16520476)
14. G.E. Umpierrez, W. Woo, W.A. Hagopian, S.D. Isaacs, J.P. Palmer, L.K. Gaur, and et al. Immunogenetic analysis suggests different pathogenesis for obese and lean African-Americans with diabetic ketoacidosis Diabetes Care 22 1999 1517 1523 (PMID: 10480519)