Distribution of the blaOXA-23-containing transposons Tn2006 and Tn2008 in Australian carbapenem-resistant Acinetobacter baumannii isolates

Journal of Antimicrobial Chemotherapy

Volumn 70, Issue 8, 2015, Pages 2409-2411

  Nigro, Steven ^a   Hall, Ruth M ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

A. baumannii; Carbapenem resistance; ISAba1

Indexed keywords

BACTERIAL PROTEIN; BLA OXA 23 PROTEIN; CARBAPENEM; IMIPENEM; MEROPENEM; TN2006 PROTEIN; TN2008 PROTEIN; UNCLASSIFIED DRUG; BACTERIAL DNA; BETA LACTAMASE; BETA-LACTAMASE OXA-23; TRANSPOSON;

ACINETOBACTER BAUMANNII; AUSTRALIAN; BACTERIAL GENE; BACTERIUM ISOLATE; BLA OXA 23 GENE; CARBAPENEM RESISTANT ACINETOBACTER BAUMANNII; GENE DUPLICATION; GENE SEQUENCE; LETTER; NONHUMAN; TRANSPOSON; ACINETOBACTER INFECTION; ANTIBIOTIC RESISTANCE; AUSTRALIA; CHEMISTRY; DNA SEQUENCE; DRUG EFFECTS; ENZYMOLOGY; GENE ORDER; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MOLECULAR GENETICS; SECRETION (PROCESS); SEQUENCE HOMOLOGY;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; AUSTRALIA; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; GENE ORDER; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY;

EID: 84939498529     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkv102     Document Type: Letter

References (12)

1. ScaifeW, Young HK, Paton RH et al. Transferable imipenem resistance in Acinetobacter species from a clinical source. J Antimicrob Chemother 1995; 36: 585-6.
2. Mugnier PD, Poirel L, Naas T et al. Worldwide dissemination of the blaOXA-23 carbapenemase gene of Acinetobacter baumannii. Emerg Infect Dis 2010; 16: 35-40.
3. Nigro SJ, Post V, Hall RM. Aminoglycoside resistance in multiply antibiotic-resistant Acinetobacter baumannii belonging to global clone 2 from Australian hospitals. J Antimicrob Chemother 2011; 66: 1504-9.
4. Wang X, Zong Z, Lu X. Tn2008 is a major vehicle carrying blaOXA-23 in Acinetobacter baumannii from China. Diagn Microbiol Infect Dis 2011; 69: 218-22.
5. Poirel L, Figueiredo S, Cattoir V et al. Acinetobacter radioresistens as a silent source of carbapenem resistance for Acinetobacter spp. Antimicrob Agents Chemother 2008; 52: 1252-6.
6. Segal H, Jacobson RK, Garny S et al. Extended 210 promoter in ISAba-1 upstream of blaOXA-23 from Acinetobacter baumannii. Antimicrob Agents Chemother 2007; 51: 3040-1.
7. Mugnier PD, Poirel L, Nordmann P. Functional analysis of insertion sequence ISAba1, responsible for genomic plasticity of Acinetobacter baumannii. J Bacteriol 2009; 191: 2414-8.
8. Nigro SJ, Hall RM. Tn6167, an antibiotic resistance island in an Australian carbapenem-resistant Acinetobacter baumannii GC2, ST92 isolate. J Antimicrob Chemother 2012; 67: 1342-6.
9. Adams-Haduch JM, Paterson DL, Sidjabat HE et al. Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania. Antimicrob Agents Chemother 2008; 52: 3837-43.
10. Nigro SJ, Holt KE, Pickard D et al. Carbapenem and amikacin resistance on a large conjugative Acinetobacter baumannii plasmid. J Antimicrob Chemother 2015; 70: 1259-61.
11. Eijkelkamp BA, Stroeher UH, Hassan KA et al. Adherence and motility characteristics of clinical Acinetobacter baumannii isolates. FEMS Microbiol Lett 2011; 323: 44-51.
12. Gheorghe I, Novais Â, Grosso F et al. Snapshot on carbapenemaseproducing Pseudomonas aeruginosa and Acinetobacter baumannii in Bucharest hospitals reveals unusual clones and novel genetic surroundings for blaOXA-23. J Antimicrob Chemother 2015; 70: 1016-20.