MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet

Cardiovascular Diabetology

Volumn 14, Issue 1, 2015, Pages

  He, Jun ^a,b   Quintana, Megan T ^a   Sullivan, Jenyth ^c   Parry, Traci ^a   Grevengoed, Trisha ^d   Schisler, Jonathan C ^a   Hill, Joseph A ^e   Yates, Cecelia C ^f   Mapanga, Rudo F ^g   Essop, M Faadiel ^g   Stansfield, William E ^a   Bain, James R ^h,i   Newgard, Christopher B ^h,i   Muehlbauer, Michael J ^h   Han, Yipin ^j   Clarke, Brian A ^k   Willis, Monte S ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NINGXIA MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d IL   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f UNIVERSITY OF PITTSBURGH   (United States)

^g STELLENBOSCH UNIVERSITY   (South Africa)

^h DUKE UNIVERSITY   (United States)

ⁱ DUKE UNIVERSITY MEDICAL CENTER   (United States)

^j East Chapel High School   (United States)

^k NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

more..

Author keywords

Diabetic cardiomyopathy; Multi ubiquitin; MuRF2; Post translational modification; PPAR; Ubiquitin ligase

Indexed keywords

ALPHA ACTIN; BRAIN NATRIURETIC PEPTIDE; GLUCOSE; GLYCOGEN; MESSENGER RNA; MUSCLE RING FINGER 2; MYOSIN HEAVY CHAIN ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 1; TRIACYLGLYCEROL; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; MUSCLE PROTEIN; MUSCLE RING FINGER 2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SIZE; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DISEASE ASSOCIATION; ECHOCARDIOGRAPHY; FATTY ACID METABOLISM; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; HEART LEFT VENTRICLE MASS; HEART MUSCLE CELL; HEART PROTECTION; HEART WEIGHT; HISTOPATHOLOGY; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; INTRACELLULAR SIGNALING; LIPID DIET; MALE; METABOLOMICS; MOLECULAR DYNAMICS; MORPHOMETRICS; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROCESSING; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC DYSFUNCTION; UBIQUITINATION; WEIGHT GAIN; WILD TYPE; ANIMAL; CARDIAC MUSCLE; CARDIOMYOPATHIES; DEFICIENCY; DISEASE MODEL; ENZYMOLOGY; GENETICS; GENOTYPE; KNOCKOUT MOUSE; METABOLISM; OBESITY; PHENOTYPE; SIGNAL TRANSDUCTION; TIME FACTOR;

ANIMALS; CARDIOMYOPATHIES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; INSULIN RESISTANCE; MALE; MICE, KNOCKOUT; MUSCLE PROTEINS; MYOCARDIUM; OBESITY; PHENOTYPE; PPAR GAMMA; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; UBIQUITINATION; WEIGHT GAIN;

EID: 84939446945     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-015-0252-x     Document Type: Article

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