Neprilysin: Biotarget and Biomarker in Heart Failure

JACC: Heart Failure

Volumn 3, Issue 8, 2015, Pages 645-646

  Seronde, Marie France ^a,b,c,d,e   Mebazaa, Alexandre ^b,c,d,e  

^a UNIVERSITY HOSPITAL JEAN MINJOZ   (France)

^b Hôpitaux de Paris   (France)

^c HÔPITAL LARIBOISIÈRE   (France)

^d INSERM   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Acute heart failure; Neprilysin; Prognosis

Indexed keywords

ADRENOMEDULLIN; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; ATRIAL NATRIURETIC FACTOR; BRADYKININ; BRAIN NATRIURETIC PEPTIDE; ENALAPRIL; MEMBRANE METALLOENDOPEPTIDASE; SACUBITRIL PLUS VALSARTAN; TROPONIN; BIOLOGICAL MARKER;

CARDIOVASCULAR MORTALITY; CLINICAL TRIAL (TOPIC); DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG RESPONSE; EDITORIAL; ENZYME ACTIVITY; HEART FAILURE; HEART MUSCLE INJURY; HOSPITAL READMISSION; HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; WALL STRESS; BLOOD; FEMALE; MALE;

BIOMARKERS; FEMALE; HEART FAILURE; HUMANS; MALE; NEPRILYSIN;

EID: 84939441356     PISSN: 22131779     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchf.2015.04.006     Document Type: Editorial

References (6)

1. Braunwald E. The path to an angiotensin receptor antagonist-neprilysin inhibitor in the treatment of heart failure. J Am Coll Cardiol 2015, 65:1029-1041.
2. McMurray J.J., Packer M., Desai A.S., et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med 2014, 371:993-1004.
3. Packer M., McMurray J.J., Desai A.S., et al. Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure. Circulation 2015, 131:54-61.
4. Bayés-Genís A., Barallat J., Galan A., et al. Soluble neprilysin is predictive of cardiovascular death and heart failure hospitalization in heart failure patients. J Am Coll Cardiol 2015, 65:657-665.
5. Bayés-Genís A., Barallat J., Pascual D., et al. Prognostic value and kinetics of soluble neprilysin in acute heart failure: a pilot study. J Am Coll Cardiol HF 2015, 3:641-644.
6. Vodovar N., Séronde M.-F., Laribi S., et al. Elevated plasma B-Type natriuretic concentrations directly inhibit circulating neprilysin activity in heart failure. J Am Coll Cardiol HF 2015, 3:629-636.