-
1
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A et al (2009) Finding the missing heritability of complex diseases. Nature 461(7265):747-753.
-
(2009)
Nature
, vol.461
, Issue.7265
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
McCarthy, M.I.7
Ramos, E.M.8
Cardon, L.R.9
Chakravarti, A.10
-
2
-
-
79957604678
-
Principles for the post-GWAS functional characterization of cancer risk loci
-
Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D et al (2011) Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet 43(6):513-518.
-
(2011)
Nat Genet
, vol.43
, Issue.6
, pp. 513-518
-
-
Freedman, M.L.1
Monteiro, A.N.2
Gayther, S.A.3
Coetzee, G.A.4
Risch, A.5
Plass, C.6
Casey, G.7
De Biasi, M.8
Carlson, C.9
Duggan, D.10
-
4
-
-
83055180602
-
Phenomics-technologies to relieve the phenotyping bottleneck
-
Furbank RT, Tester M (2011) Phenomics-technologies to relieve the phenotyping bottleneck. Trends Plant Sci 16(12):635-644.
-
(2011)
Trends Plant Sci
, vol.16
, Issue.12
, pp. 635-644
-
-
Furbank, R.T.1
Tester, M.2
-
5
-
-
0019302053
-
Construction of a genetic linkage map in man using restriction fragment length polymorphisms
-
Botstein D, White RL, Skolnick M, Davis RW (1980) Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet 32:314-331.
-
(1980)
Am J Hum Genet
, vol.32
, pp. 314-331
-
-
Botstein, D.1
White, R.L.2
Skolnick, M.3
Davis, R.W.4
-
6
-
-
0007758208
-
Polymorphism of DNA sequence adjacent to human beta-globin structural gene: Relationship to sickle mutation
-
Kan YW, Dozy AM (1978) Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation. Proc Natl Acad Sci U S A 75(11):5631-5635.
-
(1978)
Proc Natl Acad Sci U S A
, vol.75
, Issue.11
, pp. 5631-5635
-
-
Kan, Y.W.1
Dozy, A.M.2
-
7
-
-
0028834605
-
AFLP: A new technique for DNA fingerprinting
-
Vos P, Hogers R, Bleeker M, Reijans M, van de Lee T, Hornes M, Frijters A, Pot J, Peleman J, Kuiper M et al (1995) AFLP: a new technique for DNA fingerprinting. Nucleic Acids Res 23(21):4407-4414.
-
(1995)
Nucleic Acids Res
, vol.23
, Issue.21
, pp. 4407-4414
-
-
Vos, P.1
Hogers, R.2
Bleeker, M.3
Reijans, M.4
Van De Lee, T.5
Hornes, M.6
Frijters, A.7
Pot, J.8
Peleman, J.9
Kuiper, M.10
-
9
-
-
0030861903
-
The use of a genetic map of biallelic markers in linkage studies
-
Kruglyak L (1997) The use of a genetic map of biallelic markers in linkage studies. Nat Genet 17(1):21-24.
-
(1997)
Nat Genet
, vol.17
, Issue.1
, pp. 21-24
-
-
Kruglyak, L.1
-
10
-
-
0032524383
-
Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome
-
Wang DG, Fan JB, Siao CJ, Berno A, Young P, Sapolsky R, Ghandour G, Perkins N, Winchester E, Spencer J et al (1998) Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science 280(5366):1077-1082.
-
(1998)
Science
, vol.280
, Issue.5366
, pp. 1077-1082
-
-
Wang, D.G.1
Fan, J.B.2
Siao, C.J.3
Berno, A.4
Young, P.5
Sapolsky, R.6
Ghandour, G.7
Perkins, N.8
Winchester, E.9
Spencer, J.10
-
11
-
-
18144425478
-
A genome-wide scalable SNP genotyping assay using microarray technology
-
Gunderson KL, Steemers FJ, Lee G, Mendoza LG, Chee MS (2005) A genome-wide scalable SNP genotyping assay using microarray technology. Nat Genet 37(5):549-554.
-
(2005)
Nat Genet
, vol.37
, Issue.5
, pp. 549-554
-
-
Gunderson, K.L.1
Steemers, F.J.2
Lee, G.3
Mendoza, L.G.4
Chee, M.S.5
-
12
-
-
20044369371
-
Toward genome-wide SNP genotyping
-
Syvanen AC (2005) Toward genome-wide SNP genotyping. Nat Genet 37(Suppl):S5-S10.
-
(2005)
Nat Genet
, vol.37
-
-
Syvanen, A.C.1
-
13
-
-
79959435199
-
Genomewide genetic marker discovery and genotyping using next-generation sequencing
-
Davey JW, Hohenlohe PA, Etter PD, Boone JQ, Catchen JM, Blaxter ML (2011) Genomewide genetic marker discovery and genotyping using next-generation sequencing. Nat Rev Genet 12(7):499-510.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.7
, pp. 499-510
-
-
Davey, J.W.1
Hohenlohe, P.A.2
Etter, P.D.3
Boone, J.Q.4
Catchen, J.M.5
Blaxter, M.L.6
-
14
-
-
79956314887
-
Genotype and SNP calling from nextgeneration sequencing data
-
Nielsen R, Paul JS, Albrechtsen A, Song YS (2011) Genotype and SNP calling from nextgeneration sequencing data. Nat Rev Genet 12(6):443-451.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.6
, pp. 443-451
-
-
Nielsen, R.1
Paul, J.S.2
Albrechtsen, A.3
Song, Y.S.4
-
15
-
-
40149098690
-
SNP discovery and allele frequency estimation by deep sequencing of reduced representation libraries
-
Van Tassell CP, Smith TP, Matukumalli LK, Taylor JF, Schnabel RD, Lawley CT, Haudenschild CD, Moore SS, Warren WC, Sonstegard TS (2008) SNP discovery and allele frequency estimation by deep sequencing of reduced representation libraries. NatMethods 5(3):247-252.
-
(2008)
Natmethods
, vol.5
, Issue.3
, pp. 247-252
-
-
Van Tassell, C.P.1
Smith, T.P.2
Matukumalli, L.K.3
Taylor, J.F.4
Schnabel, R.D.5
Lawley, C.T.6
Haudenschild, C.D.7
Moore, S.S.8
Warren, W.C.9
Sonstegard, T.S.10
-
16
-
-
43149110423
-
Complexity reduction of polymorphic sequences (CRoPS): A novel approach for large-scale polymorphism discovery in complex genomes
-
van Orsouw NJ, Hogers RC, Janssen A, Yalcin F, Snoeijers S, Verstege E, Schneiders H, van der Poel H, van Oeveren J, Verstegen H et al (2007) Complexity reduction of polymorphic sequences (CRoPS): a novel approach for large-scale polymorphism discovery in complex genomes. PLoS One 2(11):e1172.
-
(2007)
Plos One
, vol.2
, Issue.11
-
-
Van Orsouw, N.J.1
Hogers, R.C.2
Janssen, A.3
Yalcin, F.4
Snoeijers, S.5
Verstege, E.6
Schneiders, H.7
Van Der Poel, H.8
Van Oeveren, J.9
Verstegen, H.10
-
17
-
-
54449098752
-
Rapid SNP discovery and genetic mapping using sequenced RAD markers
-
Baird NA, Etter PD, Atwood TS, Currey MC, Shiver AL, Lewis ZA, Selker EU, Cresko WA, Johnson EA (2008) Rapid SNP discovery and genetic mapping using sequenced RAD markers. PLoS One 3(10):e3376.
-
(2008)
Plos One
, vol.3
, Issue.10
-
-
Baird, N.A.1
Etter, P.D.2
Atwood, T.S.3
Currey, M.C.4
Shiver, A.L.5
Lewis, Z.A.6
Selker, E.U.7
Cresko, W.A.8
Johnson, E.A.9
-
18
-
-
79953304894
-
Multiplexed shotgun genotyping for rapid and efficient genetic mapping
-
Andolfatto P, Davison D, Erezyilmaz D, Hu TT, Mast J, Sunayama-Morita T, Stern DL (2011) Multiplexed shotgun genotyping for rapid and efficient genetic mapping. Genome Res 21(4):610-617.
-
(2011)
Genome Res
, vol.21
, Issue.4
, pp. 610-617
-
-
Andolfatto, P.1
Davison, D.2
Erezyilmaz, D.3
Hu, T.T.4
Mast, J.5
Sunayama-Morita, T.6
Stern, D.L.7
-
19
-
-
79955783956
-
A robust, simple genotyping-by-sequencing (GBS) approach for high diversity species
-
Elshire RJ, Glaubitz JC, Sun Q, Poland JA, Kawamoto K, Buckler ES, Mitchell SE (2011) A robust, simple genotyping-by-sequencing (GBS) approach for high diversity species. PLoS One 6(5):e19379.
-
(2011)
Plos One
, vol.6
, Issue.5
-
-
Elshire, R.J.1
Glaubitz, J.C.2
Sun, Q.3
Poland, J.A.4
Kawamoto, K.5
Buckler, E.S.6
Mitchell, S.E.7
-
20
-
-
62549085618
-
Human genetic variation and its contribution to complex traits
-
Frazer KA, Murray SS, Schork NJ, Topol EJ (2009) Human genetic variation and its contribution to complex traits. Nat Rev Genet 10(4):241-251.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.4
, pp. 241-251
-
-
Frazer, K.A.1
Murray, S.S.2
Schork, N.J.3
Topol, E.J.4
-
21
-
-
0037250403
-
The SNP Consortium website: Past, present and future
-
Thorisson GA, Stein LD (2003) The SNP Consortium website: past, present and future. Nucleic Acids Res 31(1):124-127.
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.1
, pp. 124-127
-
-
Thorisson, G.A.1
Stein, L.D.2
-
22
-
-
79959503826
-
The International HapMap project
-
International HapMap C (2003) The International HapMap project. Nature 426(6968): 789-796.
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 789-796
-
-
-
24
-
-
84975742565
-
A map of human genome variation from populationscale sequencing
-
Genomes Project C, Abecasis GR, Altshuler D, Auton A, Brooks LD, Durbin RM, Gibbs RA, Hurles ME, McVean GA (2010) A map of human genome variation from populationscale sequencing. Nature 467(7319):1061-1073.
-
(2010)
Nature
, vol.467
, Issue.7319
, pp. 1061-1073
-
-
Genomes Project, C.1
Abecasis, G.R.2
Altshuler, D.3
Auton, A.4
Brooks, L.D.5
Durbin, R.M.6
Gibbs, R.A.7
Hurles, M.E.8
McVean, G.A.9
-
25
-
-
77954319020
-
Sequencing of 50 human exomes reveals adaptation to high altitude
-
Yi X, Liang Y, Huerta-Sanchez E, Jin X, Cuo ZX, Pool JE, Xu X, Jiang H, Vinckenbosch N, Korneliussen TS et al (2010) Sequencing of 50 human exomes reveals adaptation to high altitude. Science 329(5987):75-78.
-
(2010)
Science
, vol.329
, Issue.5987
, pp. 75-78
-
-
Yi, X.1
Liang, Y.2
Huerta-Sanchez, E.3
Jin, X.4
Cuo, Z.X.5
Pool, J.E.6
Xu, X.7
Jiang, H.8
Vinckenbosch, N.9
Korneliussen, T.S.10
-
26
-
-
84975795680
-
An integrated map of genetic variation from 1,092 human genomes
-
Genomes Project C, Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, Kang HM, Marth GT, McVean GA (2012) An integrated map of genetic variation from 1,092 human genomes. Nature 491(7422):56-65.
-
(2012)
Nature
, vol.491
, Issue.7422
, pp. 56-65
-
-
Genomes Project, C.1
Abecasis, G.R.2
Auton, A.3
Brooks, L.D.4
Depristo, M.A.5
Durbin, R.M.6
Handsaker, R.E.7
Kang, H.M.8
Marth, G.T.9
McVean, G.A.10
-
27
-
-
77953233453
-
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines
-
Atwell S, Huang YS, Vilhjalmsson BJ, Willems G, Horton M, Li Y, Meng D, Platt A, Tarone AM, Hu TT et al (2010) Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature 465(7298):627-631.
-
(2010)
Nature
, vol.465
, Issue.7298
, pp. 627-631
-
-
Atwell, S.1
Huang, Y.S.2
Vilhjalmsson, B.J.3
Willems, G.4
Horton, M.5
Li, Y.6
Meng, D.7
Platt, A.8
Tarone, A.M.9
Hu, T.T.10
-
28
-
-
78049332150
-
Genome-wide association studies of 14 agronomic traits in rice landraces
-
Huang X, Wei X, Sang T, Zhao Q, Feng Q, Zhao Y, Li C, Zhu C, Lu T, Zhang Z et al (2010) Genome-wide association studies of 14 agronomic traits in rice landraces. Nat Genet 42(11):961-967.
-
(2010)
Nat Genet
, vol.42
, Issue.11
, pp. 961-967
-
-
Huang, X.1
Wei, X.2
Sang, T.3
Zhao, Q.4
Feng, Q.5
Zhao, Y.6
Li, C.7
Zhu, C.8
Lu, T.9
Zhang, Z.10
-
29
-
-
70450204614
-
A first-generation haplotype map of maize
-
Gore MA, Chia JM, Elshire RJ, Sun Q, Ersoz ES, Hurwitz BL, Peiffer JA, McMullen MD, Grills GS, Ross-Ibarra J et al (2009) A first-generation haplotype map of maize. Science 326(5956):1115-1117.
-
(2009)
Science
, vol.326
, Issue.5956
, pp. 1115-1117
-
-
Gore, M.A.1
Chia, J.M.2
Elshire, R.J.3
Sun, Q.4
Ersoz, E.S.5
Hurwitz, B.L.6
Peiffer, J.A.7
McMullen, M.D.8
Grills, G.S.9
Ross-Ibarra, J.10
-
30
-
-
78049338441
-
Genome-wide patterns of genetic variation among elite maize inbred lines
-
Lai J, Li R, Xu X, Jin W, Xu M, Zhao H, Xiang Z, Song W, Ying K, Zhang M et al (2010) Genome-wide patterns of genetic variation among elite maize inbred lines. Nat Genet 42(11):1027-1030.
-
(2010)
Nat Genet
, vol.42
, Issue.11
, pp. 1027-1030
-
-
Lai, J.1
Li, R.2
Xu, X.3
Jin, W.4
Xu, M.5
Zhao, H.6
Xiang, Z.7
Song, W.8
Ying, K.9
Zhang, M.10
-
31
-
-
81355147024
-
Genome-wide patterns of genetic variation in sweet and grain sorghum (Sorghum bicolor)
-
Zheng LY, Guo XS, He B, Sun LJ, Peng Y, Dong SS, Liu TF, Jiang S, Ramachandran S, Liu CM et al (2011) Genome-wide patterns of genetic variation in sweet and grain sorghum (Sorghum bicolor). Genome Biol 12(11):R114.
-
(2011)
Genome Biol
, vol.12
, Issue.11
-
-
Zheng, L.Y.1
Guo, X.S.2
He, B.3
Sun, L.J.4
Peng, Y.5
Dong, S.S.6
Liu, T.F.7
Jiang, S.8
Ramachandran, S.9
Liu, C.M.10
-
32
-
-
78650727753
-
Genome-wide association mapping to candidate polymorphism resolution in the unsequenced barley genome
-
Cockram J, White J, Zuluaga DL, Smith D, Comadran J, Macaulay M, Luo Z, Kearsey MJ, Werner P, Harrap D et al (2010) Genome-wide association mapping to candidate polymorphism resolution in the unsequenced barley genome. Proc Natl Acad Sci U S A 107(50):21611-21616.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.50
, pp. 21611-21616
-
-
Cockram, J.1
White, J.2
Zuluaga, D.L.3
Smith, D.4
Comadran, J.5
MacAulay, M.6
Luo, Z.7
Kearsey, M.J.8
Werner, P.9
Harrap, D.10
-
33
-
-
0014410839
-
Towards a theoretical biology
-
Waddington CH (1968) Towards a theoretical biology. Nature 218(5141):525-527.
-
(1968)
Nature
, vol.218
, Issue.5141
, pp. 525-527
-
-
Waddington, C.H.1
-
34
-
-
77649266028
-
Visualization of image data from cells to organisms
-
Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S et al (2010) Visualization of image data from cells to organisms. Nat Methods 7(3 Suppl):S26-S41.
-
(2010)
Nat Methods
, vol.7
, Issue.3
, pp. S26-S41
-
-
Walter, T.1
Shattuck, D.W.2
Baldock, R.3
Bastin, M.E.4
Carpenter, A.E.5
Duce, S.6
Ellenberg, J.7
Fraser, A.8
Hamilton, N.9
Pieper, S.10
-
35
-
-
8444223104
-
Multidimensional drug profiling by automated microscopy
-
Perlman ZE, Slack MD, Feng Y, Mitchison TJ, Wu LF, Altschuler SJ (2004) Multidimensional drug profiling by automated microscopy. Science 306(5699):1194-1198.
-
(2004)
Science
, vol.306
, Issue.5699
, pp. 1194-1198
-
-
Perlman, Z.E.1
Slack, M.D.2
Feng, Y.3
Mitchison, T.J.4
Wu, L.F.5
Altschuler, S.J.6
-
36
-
-
33646057010
-
High-throughput RNAi screening by time-lapse imaging of live human cells
-
Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J (2006) High-throughput RNAi screening by time-lapse imaging of live human cells. Nat Methods 3(5):385-390.
-
(2006)
Nat Methods
, vol.3
, Issue.5
, pp. 385-390
-
-
Neumann, B.1
Held, M.2
Liebel, U.3
Erfle, H.4
Rogers, P.5
Pepperkok, R.6
Ellenberg, J.7
-
37
-
-
34250882643
-
Quantitative morphological signatures define local signaling networks regulating cell morphology
-
Bakal C, Aach J, Church G, Perrimon N (2007) Quantitative morphological signatures define local signaling networks regulating cell morphology. Science 316(5832):1753-1756.
-
(2007)
Science
, vol.316
, Issue.5832
, pp. 1753-1756
-
-
Bakal, C.1
Aach, J.2
Church, G.3
Perrimon, N.4
-
38
-
-
34250216344
-
Image-based multivariate profiling of drug responses from single cells
-
Loo LH, Wu LF, Altschuler SJ (2007) Image-based multivariate profiling of drug responses from single cells. Nat Methods 4(5):445-453.
-
(2007)
Nat Methods
, vol.4
, Issue.5
, pp. 445-453
-
-
Loo, L.H.1
Wu, L.F.2
Altschuler, S.J.3
-
39
-
-
60549104030
-
Scoring diverse cellular morphologies in imagebased screens with iterative feedback and machine learning
-
Jones TR, Carpenter AE, Lamprecht MR, Moffat J, Silver SJ, Grenier JK, Castoreno AB, Eggert US, Root DE, Golland P et al (2009) Scoring diverse cellular morphologies in imagebased screens with iterative feedback and machine learning. Proc Natl Acad Sci U S A 106(6):1826-1831.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.6
, pp. 1826-1831
-
-
Jones, T.R.1
Carpenter, A.E.2
Lamprecht, M.R.3
Moffat, J.4
Silver, S.J.5
Grenier, J.K.6
Castoreno, A.B.7
Eggert, U.S.8
Root, D.E.9
Golland, P.10
-
40
-
-
77949424084
-
Systems survey of endocytosis by multiparametric image analysis
-
Collinet C, Stoter M, Bradshaw CR, Samusik N, Rink JC, Kenski D, Habermann B, Buchholz F, Henschel R, Mueller MS et al (2010) Systems survey of endocytosis by multiparametric image analysis. Nature 464(7286):243-249.
-
(2010)
Nature
, vol.464
, Issue.7286
, pp. 243-249
-
-
Collinet, C.1
Stoter, M.2
Bradshaw, C.R.3
Samusik, N.4
Rink, J.C.5
Kenski, D.6
Habermann, B.7
Buchholz, F.8
Henschel, R.9
Mueller, M.S.10
-
41
-
-
77953276042
-
Clustering phenotype populations by genome-wide RNAi and multiparametric imaging
-
Fuchs F, Pau G, Kranz D, Sklyar O, Budjan C, Steinbrink S, Horn T, Pedal A, Huber W, Boutros M (2010) Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Mol Syst Biol 6:370.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 370
-
-
Fuchs, F.1
Pau, G.2
Kranz, D.3
Sklyar, O.4
Budjan, C.5
Steinbrink, S.6
Horn, T.7
Pedal, A.8
Huber, W.9
Boutros, M.10
-
42
-
-
33749537857
-
Genome-wide functional analysis of human cell-cycle regulators
-
Mukherji M, Bell R, Supekova L, Wang Y, Orth AP, Batalov S, Miraglia L, Huesken D, Lange J, Martin C et al (2006) Genome-wide functional analysis of human cell-cycle regulators. Proc Natl Acad Sci U S A 103(40):14819-14824.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.40
, pp. 14819-14824
-
-
Mukherji, M.1
Bell, R.2
Supekova, L.3
Wang, Y.4
Orth, A.P.5
Batalov, S.6
Miraglia, L.7
Huesken, D.8
Lange, J.9
Martin, C.10
-
43
-
-
0346728473
-
Systematic genome-wide screens of gene function
-
Carpenter AE, Sabatini DM (2004) Systematic genome-wide screens of gene function. Nat Rev Genet 5(1):11-22.
-
(2004)
Nat Rev Genet
, vol.5
, Issue.1
, pp. 11-22
-
-
Carpenter, A.E.1
Sabatini, D.M.2
-
44
-
-
33747624926
-
High-throughput fluorescence microscopy for systems biology
-
Pepperkok R, Ellenberg J (2006) High-throughput fluorescence microscopy for systems biology. Nat Rev Mol Cell Biol 7(9):690-696.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.9
, pp. 690-696
-
-
Pepperkok, R.1
Ellenberg, J.2
-
46
-
-
77951959633
-
EBImage-an R package for image processing with applications to cellular phenotypes
-
Pau G, Fuchs F, Sklyar O, Boutros M, Huber W (2010) EBImage-an R package for image processing with applications to cellular phenotypes. Bioinformatics 26(7):979-981.
-
(2010)
Bioinformatics
, vol.26
, Issue.7
, pp. 979-981
-
-
Pau, G.1
Fuchs, F.2
Sklyar, O.3
Boutros, M.4
Huber, W.5
-
47
-
-
33845792555
-
Cell Profiler: Image analysis software for identifying and quantifying cell phenotypes
-
Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, Guertin DA, Chang JH, Lindquist RA, Moffat J et al (2006) Cell Profiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 7(10):R100.
-
(2006)
Genome Biol
, vol.7
, Issue.10
-
-
Carpenter, A.E.1
Jones, T.R.2
Lamprecht, M.R.3
Clarke, C.4
Kang, I.H.5
Friman, O.6
Guertin, D.A.7
Chang, J.H.8
Lindquist, R.A.9
Moffat, J.10
-
48
-
-
84863192185
-
PhenoRipper: Software for rapidly profiling microscopy images
-
Rajaram S, Pavie B, Wu LF, Altschuler SJ (2012) PhenoRipper: software for rapidly profiling microscopy images. Nat Methods 9(7):635-637.
-
(2012)
Nat Methods
, vol.9
, Issue.7
, pp. 635-637
-
-
Rajaram, S.1
Pavie, B.2
Wu, L.F.3
Altschuler, S.J.4
-
49
-
-
84877682482
-
Future scenarios for plant phenotyping
-
Fiorani F, Schurr U (2013) Future scenarios for plant phenotyping. Annu Rev Plant Biol 64(1):267-291.
-
(2013)
Annu Rev Plant Biol
, vol.64
, Issue.1
, pp. 267-291
-
-
Fiorani, F.1
Schurr, U.2
-
50
-
-
79952816408
-
TraitMill: A discovery engine for identifying yield-enhancement genes in cereals
-
Reuzeau C, Pen J, Frankard V, de Wolf J, Peerbolte R, Broekaert W (2005) TraitMill: a discovery engine for identifying yield-enhancement genes in cereals. Fenzi Zhiwu Yuzhong (Mol Plant Breed) 3:7534.
-
(2005)
Fenzi Zhiwu Yuzhong (Mol Plant Breed)
, vol.3
, pp. 7534
-
-
Reuzeau, C.1
Pen, J.2
Frankard, V.3
De Wolf, J.4
Peerbolte, R.5
Broekaert, W.6
-
51
-
-
33645051449
-
PHENOPSIS, an automated platform for reproducible phenotyping of plant responses to soil water deficit in Arabidopsis thaliana permitted the identification of an accession with low sensitivity to soil water deficit
-
Granier C, Aguirrezabal L, Chenu K, Cookson SJ, Dauzat M, Hamard P, Thioux JJ, Rolland G, Bouchier-Combaud S, Lebaudy A et al (2006) PHENOPSIS, an automated platform for reproducible phenotyping of plant responses to soil water deficit in Arabidopsis thaliana permitted the identification of an accession with low sensitivity to soil water deficit. New Phytol 169(3):623-635.
-
(2006)
New Phytol
, vol.169
, Issue.3
, pp. 623-635
-
-
Granier, C.1
Aguirrezabal, L.2
Chenu, K.3
Cookson, S.J.4
Dauzat, M.5
Hamard, P.6
Thioux, J.J.7
Rolland, G.8
Bouchier-Combaud, S.9
Lebaudy, A.10
-
52
-
-
33646592893
-
Traitmill™: A functional genomics platform for the phenotypic analysis of cereals
-
Reuzeau C, Frankard V, Hatzfeld Y, Sanz A, Van Camp W, Lejeune P, De Wilde C, Lievens K, de Wolf J, Vranken E et al (2006) Traitmill™: a functional genomics platform for the phenotypic analysis of cereals. Plant Genet Resour 4(01):20-24.
-
(2006)
Plant Genet Resour
, vol.4
, Issue.1
, pp. 20-24
-
-
Reuzeau, C.1
Frankard, V.2
Hatzfeld, Y.3
Sanz, A.4
Van Camp, W.5
Lejeune, P.6
De Wilde, C.7
Lievens, K.8
De Wolf, J.9
Vranken, E.10
-
53
-
-
33947418028
-
Dynamics of seedling growth acclimation towards altered light conditions can be quantified via GROWSCREEN: A setup and procedure designed for rapid optical phenotyping of different plant species
-
Walter A, Scharr H, Gilmer F, Zierer R, Nagel KA, Ernst M, Wiese A, Virnich O, Christ MM, Uhlig B et al (2007) Dynamics of seedling growth acclimation towards altered light conditions can be quantified via GROWSCREEN: a setup and procedure designed for rapid optical phenotyping of different plant species. New Phytol 174(2):447-455.
-
(2007)
New Phytol
, vol.174
, Issue.2
, pp. 447-455
-
-
Walter, A.1
Scharr, H.2
Gilmer, F.3
Zierer, R.4
Nagel, K.A.5
Ernst, M.6
Wiese, A.7
Virnich, O.8
Christ, M.M.9
Uhlig, B.10
-
54
-
-
49249101759
-
LAMINA: A tool for rapid quantification of leaf size and shape parameters
-
Bylesjo M, Segura V, Soolanayakanahally RY, Rae AM, Trygg J, Gustafsson P, Jansson S, Street NR (2008) LAMINA: a tool for rapid quantification of leaf size and shape parameters. BMC Plant Biol 8:82.
-
(2008)
BMC Plant Biol
, vol.8
, pp. 82
-
-
Bylesjo, M.1
Segura, V.2
Soolanayakanahally, R.Y.3
Rae, A.M.4
Trygg, J.5
Gustafsson, P.6
Jansson, S.7
Street, N.R.8
-
55
-
-
70449686674
-
Simultaneous phenotyping of leaf growth and chlorophyll fluorescence via GROWSCREEN FLUORO allows detection of stress tolerance in Arabidopsis thaliana and other rosette plants
-
Jansen M, Gilmer F, Biskup B, Nagel KA, Rascher U, Fischbach A, Briem S, Dreissen G, Tittmann S, Braun S et al (2009) Simultaneous phenotyping of leaf growth and chlorophyll fluorescence via GROWSCREEN FLUORO allows detection of stress tolerance in Arabidopsis thaliana and other rosette plants. Funct Plant Biol 36(10-11):902-914.
-
(2009)
Funct Plant Biol
, vol.36
, Issue.10-11
, pp. 902-914
-
-
Jansen, M.1
Gilmer, F.2
Biskup, B.3
Nagel, K.A.4
Rascher, U.5
Fischbach, A.6
Briem, S.7
Dreissen, G.8
Tittmann, S.9
Braun, S.10
-
56
-
-
65249097704
-
HYPOTrace: Image analysis software for measuring hypocotyl growth and shape demonstrated on Arabidopsis seedlings undergoing photomorphogenesis
-
Wang L, Uilecan IV, Assadi AH, Kozmik CA, Spalding EP (2009) HYPOTrace: image analysis software for measuring hypocotyl growth and shape demonstrated on Arabidopsis seedlings undergoing photomorphogenesis. Plant Physiol 149(4):1632-1637.
-
(2009)
Plant Physiol
, vol.149
, Issue.4
, pp. 1632-1637
-
-
Wang, L.1
Uilecan, I.V.2
Assadi, A.H.3
Kozmik, C.A.4
Spalding, E.P.5
-
57
-
-
79955830859
-
HTPheno: An image analysis pipeline for high-throughput plant phenotyping
-
Hartmann A, Czauderna T, Hoffmann R, Stein N, Schreiber F (2011) HTPheno: an image analysis pipeline for high-throughput plant phenotyping. BMC Bioinform 12:148.
-
(2011)
BMC Bioinform
, vol.12
, pp. 148
-
-
Hartmann, A.1
Czauderna, T.2
Hoffmann, R.3
Stein, N.4
Schreiber, F.5
-
58
-
-
38649136254
-
LeafAnalyser: A computational method for rapid and large-scale analyses of leaf shape variation
-
Weight C, Parnham D, Waites R (2008) LeafAnalyser: a computational method for rapid and large-scale analyses of leaf shape variation. Plant J 53(3):578-586.
-
(2008)
Plant J
, vol.53
, Issue.3
, pp. 578-586
-
-
Weight, C.1
Parnham, D.2
Waites, R.3
-
59
-
-
75849142760
-
QTL analysis of early stage heterosis for biomass in Arabidopsis
-
Meyer RC, Kusterer B, Lisec J, Steinfath M, Becher M, Scharr H, Melchinger AE, Selbig J, Schurr U, Willmitzer L et al (2010) QTL analysis of early stage heterosis for biomass in Arabidopsis. Theor Appl Genet Theoretische und angewandte Genetik 120(2):227-237.
-
(2010)
Theor Appl Genet Theoretische Und Angewandte Genetik
, vol.120
, Issue.2
, pp. 227-237
-
-
Meyer, R.C.1
Kusterer, B.2
Lisec, J.3
Steinfath, M.4
Becher, M.5
Scharr, H.6
Melchinger, A.E.7
Selbig, J.8
Schurr, U.9
Willmitzer, L.10
-
60
-
-
63549105207
-
Diel growth cycle of isolated leaf discs analyzed with a novel, high-throughput three-dimensional imaging method is identical to that of intact leaves
-
Biskup B, Scharr H, Fischbach A, Wiese-Klinkenberg A, Schurr U, Walter A (2009) Diel growth cycle of isolated leaf discs analyzed with a novel, high-throughput three-dimensional imaging method is identical to that of intact leaves. Plant Physiol 149(3):1452-1461.
-
(2009)
Plant Physiol
, vol.149
, Issue.3
, pp. 1452-1461
-
-
Biskup, B.1
Scharr, H.2
Fischbach, A.3
Wiese-Klinkenberg, A.4
Schurr, U.5
Walter, A.6
-
61
-
-
79958074246
-
Three-dimensional root phenotyping with a novel imaging and software platform
-
Clark RT, MacCurdy RB, Jung JK, Shaff JE, McCouch SR, Aneshansley DJ, Kochian LV (2011) Three-dimensional root phenotyping with a novel imaging and software platform. Plant Physiol 156(2):455-465.
-
(2011)
Plant Physiol
, vol.156
, Issue.2
, pp. 455-465
-
-
Clark, R.T.1
MacCurdy, R.B.2
Jung, J.K.3
Shaff, J.E.4
McCouch, S.R.5
Aneshansley, D.J.6
Kochian, L.V.7
-
62
-
-
80052424959
-
A novel image-analysis toolbox enabling quantitative analysis of root system architecture
-
Lobet G, Pages L, Draye X (2011) A novel image-analysis toolbox enabling quantitative analysis of root system architecture. Plant Physiol 157(1):29-39.
-
(2011)
Plant Physiol
, vol.157
, Issue.1
, pp. 29-39
-
-
Lobet, G.1
Pages, L.2
Draye, X.3
-
63
-
-
84860363173
-
A novel mesh processing based technique for 3D plant analysis
-
Paproki A, Sirault X, Berry S, Furbank R, Fripp J (2012) A novel mesh processing based technique for 3D plant analysis. BMC Plant Biol 12:63.
-
(2012)
BMC Plant Biol
, vol.12
, pp. 63
-
-
Paproki, A.1
Sirault, X.2
Berry, S.3
Furbank, R.4
Fripp, J.5
-
64
-
-
77954073619
-
High-contrast three-dimensional imaging of the Arabidopsis leaf enables the analysis of cell dimensions in the epidermis and mesophyll
-
Wuyts N, Palauqui JC, Conejero G, Verdeil JL, Granier C, Massonnet C (2010) High-contrast three-dimensional imaging of the Arabidopsis leaf enables the analysis of cell dimensions in the epidermis and mesophyll. Plant Methods 6:17.
-
(2010)
Plant Methods
, vol.6
, pp. 17
-
-
Wuyts, N.1
Palauqui, J.C.2
Conejero, G.3
Verdeil, J.L.4
Granier, C.5
Massonnet, C.6
-
65
-
-
79953039351
-
High-throughput phenotyping of multicellular organisms: Finding the link between genotype and phenotype
-
Sozzani R, Benfey PN (2011) High-throughput phenotyping of multicellular organisms: finding the link between genotype and phenotype. Genome Biol 12(3):219.
-
(2011)
Genome Biol
, vol.12
, Issue.3
, pp. 219
-
-
Sozzani, R.1
Benfey, P.N.2
-
66
-
-
79960559167
-
A growth phenotyping pipeline for Arabidopsis thaliana integrating image analysis and rosette area modeling for robust quantification of genotype effects
-
Arvidsson S, Perez-Rodriguez P, Mueller-Roeber B (2011) A growth phenotyping pipeline for Arabidopsis thaliana integrating image analysis and rosette area modeling for robust quantification of genotype effects. New Phytol 191(3):895-907.
-
(2011)
New Phytol
, vol.191
, Issue.3
, pp. 895-907
-
-
Arvidsson, S.1
Perez-Rodriguez, P.2
Mueller-Roeber, B.3
-
67
-
-
79351470088
-
Accurate inference of shoot biomass from high-throughput images of cereal plants
-
Golzarian MR, Frick RA, Rajendran K, Berger B, Roy S, Tester M, Lun DS (2011) Accurate inference of shoot biomass from high-throughput images of cereal plants. Plant Methods 7:2.
-
(2011)
Plant Methods
, vol.7
, pp. 2
-
-
Golzarian, M.R.1
Frick, R.A.2
Rajendran, K.3
Berger, B.4
Roy, S.5
Tester, M.6
Lun, D.S.7
-
68
-
-
77951204515
-
Dissection and modelling of abiotic stress tolerance in plants
-
Tardieu F, Tuberosa R (2010) Dissection and modelling of abiotic stress tolerance in plants. Curr Opin Plant Biol 13(2):206-212.
-
(2010)
Curr Opin Plant Biol
, vol.13
, Issue.2
, pp. 206-212
-
-
Tardieu, F.1
Tuberosa, R.2
-
69
-
-
84868699333
-
SPICY: Towards automated phenotyping of large pepper plants in the greenhouse
-
van der Heijden G, Song Y, Horgan G, Polder G, Dieleman A, Bink M, Palloix A, van Eeuwijk F, Glasbey C (2012) SPICY: towards automated phenotyping of large pepper plants in the greenhouse. Funct Plant Biol 39(10-11):870-877.
-
(2012)
Funct Plant Biol
, vol.39
, Issue.10-11
, pp. 870-877
-
-
Van Der Heijden, G.1
Song, Y.2
Horgan, G.3
Polder, G.4
Dieleman, A.5
Bink, M.6
Palloix, A.7
Van Eeuwijk, F.8
Glasbey, C.9
-
70
-
-
84867661862
-
Analysis of high-throughput plant image data with the information system IAP
-
Klukas C, Pape JM, Entzian A (2012) Analysis of high-throughput plant image data with the information system IAP. J Integr Bioinform 9(2):191.
-
(2012)
J Integr Bioinform
, vol.9
, Issue.2
, pp. 191
-
-
Klukas, C.1
Pape, J.M.2
Entzian, A.3
-
71
-
-
79960556965
-
Epigenome-wide association studies for common human diseases
-
Rakyan VK, Down TA, Balding DJ, Beck S (2011) Epigenome-wide association studies for common human diseases. Nat Rev Genet 12(8):529-541.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.8
, pp. 529-541
-
-
Rakyan, V.K.1
Down, T.A.2
Balding, D.J.3
Beck, S.4
-
72
-
-
76749109506
-
Breeding technologies to increase crop production in a changing world
-
Tester M, Langridge P (2010) Breeding technologies to increase crop production in a changing world. Science 327(5967):818-822.
-
(2010)
Science
, vol.327
, Issue.5967
, pp. 818-822
-
-
Tester, M.1
Langridge, P.2
-
73
-
-
84874189972
-
Genotype to phenotype: Lessons from model organisms for human genetics
-
Lehner B (2013) Genotype to phenotype: lessons from model organisms for human genetics. Nat Rev Genet 14(3):168-178.
-
(2013)
Nat Rev Genet
, vol.14
, Issue.3
, pp. 168-178
-
-
Lehner, B.1
-
74
-
-
17444403604
-
Phenotypic differences in genetically identical organisms: The epigenetic perspective
-
Wong AH, Gottesman II, Petronis A (2005) Phenotypic differences in genetically identical organisms: the epigenetic perspective. Hum Mol Genet 14(1):R11-R18.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.1
-
-
Wong, A.H.1
Gottesman, I.I.2
Petronis, A.3
-
76
-
-
84870911330
-
Deciphering and prediction of transcriptome dynamics under fluctuating field conditions
-
Nagano AJ, Sato Y, Mihara M, Antonio BA, Motoyama R, Itoh H, Nagamura Y, Izawa T (2012) Deciphering and prediction of transcriptome dynamics under fluctuating field conditions. Cell 151(6):1358-1369.
-
(2012)
Cell
, vol.151
, Issue.6
, pp. 1358-1369
-
-
Nagano, A.J.1
Sato, Y.2
Mihara, M.3
Antonio, B.A.4
Motoyama, R.5
Itoh, H.6
Nagamura, Y.7
Izawa, T.8
-
77
-
-
84870915654
-
Modeling transcriptome dynamics in a complex world
-
Jaeger PA, Doherty C, Ideker T (2012)Modeling transcriptome dynamics in a complex world. Cell 151(6):1161-1162.
-
(2012)
Cell
, vol.151
, Issue.6
, pp. 1161-1162
-
-
Jaeger, P.A.1
Doherty, C.2
Ideker, T.3
-
78
-
-
84871699802
-
Genetic analysis of metabolomephenotype interactions: From model to crop species
-
Carreno-Quintero N, Bouwmeester HJ, Keurentjes JJ (2013) Genetic analysis of metabolomephenotype interactions: from model to crop species. Trends Genet 29(1):41-50.
-
(2013)
Trends Genet
, vol.29
, Issue.1
, pp. 41-50
-
-
Carreno-Quintero, N.1
Bouwmeester, H.J.2
Keurentjes, J.J.3
-
79
-
-
55449120805
-
Genetic mapping in human disease
-
Altshuler D, Daly MJ, Lander ES (2008) Genetic mapping in human disease. Science 322(5903):881-888.
-
(2008)
Science
, vol.322
, Issue.5903
, pp. 881-888
-
-
Altshuler, D.1
Daly, M.J.2
Lander, E.S.3
-
80
-
-
57649136554
-
Progress and challenges in genome-wide association studies in humans
-
Donnelly P (2008) Progress and challenges in genome-wide association studies in humans. Nature 456(7223):728-731.
-
(2008)
Nature
, vol.456
, Issue.7223
, pp. 728-731
-
-
Donnelly, P.1
-
81
-
-
43749116419
-
Genetic approaches to crop improvement: Responding to environmental and population changes
-
Takeda S, Matsuoka M (2008) Genetic approaches to crop improvement: responding to environmental and population changes. Nat Rev Genet 9(6):444-457.
-
(2008)
Nat Rev Genet
, vol.9
, Issue.6
, pp. 444-457
-
-
Takeda, S.1
Matsuoka, M.2
-
82
-
-
79959378465
-
Family-based designs for genome-wide association studies
-
Ott J, Kamatani Y, Lathrop M (2011) Family-based designs for genome-wide association studies. Nat Rev Genet 12(7):465-474.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.7
, pp. 465-474
-
-
Ott, J.1
Kamatani, Y.2
Lathrop, M.3
-
83
-
-
45149105926
-
Efficient control of population structure in model organism association mapping
-
Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, Daly MJ, Eskin E (2008) Efficient control of population structure in model organism association mapping. Genetics 178(3):1709-1723.
-
(2008)
Genetics
, vol.178
, Issue.3
, pp. 1709-1723
-
-
Kang, H.M.1
Zaitlen, N.A.2
Wade, C.M.3
Kirby, A.4
Heckerman, D.5
Daly, M.J.6
Eskin, E.7
-
84
-
-
77950301214
-
Variance component model to account for sample structure in genome-wide association studies
-
Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E (2010) Variance component model to account for sample structure in genome-wide association studies. Nat Genet 42(4):348-354.
-
(2010)
Nat Genet
, vol.42
, Issue.4
, pp. 348-354
-
-
Kang, H.M.1
Sul, J.H.2
Service, S.K.3
Zaitlen, N.A.4
Kong, S.Y.5
Freimer, N.B.6
Sabatti, C.7
Eskin, E.8
-
85
-
-
84863003734
-
Genome-wide efficient mixed-model analysis for association studies
-
Zhou X, Stephens M (2012) Genome-wide efficient mixed-model analysis for association studies. Nat Genet 44(7):821-824.
-
(2012)
Nat Genet
, vol.44
, Issue.7
, pp. 821-824
-
-
Zhou, X.1
Stephens, M.2
-
86
-
-
34447324105
-
GenABEL: An R library for genomewide association analysis
-
Aulchenko YS, Ripke S, Isaacs A, van Duijn CM (2007) GenABEL: an R library for genomewide association analysis. Bioinformatics 23(10):1294-1296.
-
(2007)
Bioinformatics
, vol.23
, Issue.10
, pp. 1294-1296
-
-
Aulchenko, Y.S.1
Ripke, S.2
Isaacs, A.3
Van Duijn, C.M.4
-
87
-
-
80053372166
-
FaST linear mixed models for genome-wide association studies
-
Lippert C, Listgarten J, Liu Y, Kadie CM, Davidson RI, Heckerman D (2011) FaST linear mixed models for genome-wide association studies. Nat Methods 8(10):833-835.
-
(2011)
Nat Methods
, vol.8
, Issue.10
, pp. 833-835
-
-
Lippert, C.1
Listgarten, J.2
Liu, Y.3
Kadie, C.M.4
Davidson, R.I.5
Heckerman, D.6
-
88
-
-
35748946021
-
TASSEL: Software for association mapping of complex traits in diverse samples
-
Bradbury PJ, Zhang Z, Kroon DE, Casstevens TM, Ramdoss Y, Buckler ES (2007) TASSEL: software for association mapping of complex traits in diverse samples. Bioinformatics 23(19):2633-2635.
-
(2007)
Bioinformatics
, vol.23
, Issue.19
, pp. 2633-2635
-
-
Bradbury, P.J.1
Zhang, Z.2
Kroon, D.E.3
Casstevens, T.M.4
Ramdoss, Y.5
Buckler, E.S.6
-
89
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38(8):904-909.
-
(2006)
Nat Genet
, vol.38
, Issue.8
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
90
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A 106(23):9362-9367.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.23
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
91
-
-
77952557918
-
Missing heritability and strategies for finding the underlying causes of complex disease
-
Eichler EE, Flint J, Gibson G, Kong A, Leal SM, Moore JH, Nadeau JH (2010) Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet 11(6):446-450.
-
(2010)
Nat Rev Genet
, vol.11
, Issue.6
, pp. 446-450
-
-
Eichler, E.E.1
Flint, J.2
Gibson, G.3
Kong, A.4
Leal, S.M.5
Moore, J.H.6
Nadeau, J.H.7
-
92
-
-
55549147191
-
Personal genomes: The case of the missing heritability
-
Maher B (2008) Personal genomes: the case of the missing heritability. Nature 456(7218): 18-21.
-
(2008)
Nature
, vol.456
, Issue.7218
, pp. 18-21
-
-
Maher, B.1
-
93
-
-
80055004691
-
Genome-wide association studies in plants: The missing heritability is in the field
-
Brachi B, Morris GP, Borevitz JO (2011) Genome-wide association studies in plants: the missing heritability is in the field. Genome Biol 12(10):232.
-
(2011)
Genome Biol
, vol.12
, Issue.10
, pp. 232
-
-
Brachi, B.1
Morris, G.P.2
Borevitz, J.O.3
-
94
-
-
78650470891
-
Association mapping of local climate-sensitive quantitative trait loci in Arabidopsis thaliana
-
Li Y, Huang Y, Bergelson J, Nordborg M, Borevitz JO (2010) Association mapping of local climate-sensitive quantitative trait loci in Arabidopsis thaliana. Proc Natl Acad Sci U S A 107(49):21199-21204.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.49
, pp. 21199-21204
-
-
Li, Y.1
Huang, Y.2
Bergelson, J.3
Nordborg, M.4
Borevitz, J.O.5
-
95
-
-
68449083317
-
The genetic architecture of maize flowering time
-
Buckler ES, Holland JB, Bradbury PJ, Acharya CB, Brown PJ, Browne C, Ersoz E, Flint-Garcia S, Garcia A, Glaubitz JC et al (2009) The genetic architecture of maize flowering time. Science 325(5941):714-718.
-
(2009)
Science
, vol.325
, Issue.5941
, pp. 714-718
-
-
Buckler, E.S.1
Holland, J.B.2
Bradbury, P.J.3
Acharya, C.B.4
Brown, P.J.5
Browne, C.6
Ersoz, E.7
Flint-Garcia, S.8
Garcia, A.9
Glaubitz, J.C.10
-
96
-
-
84871996129
-
Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels
-
Li H, Peng Z, Yang X, Wang W, Fu J, Wang J, Han Y, Chai Y, Guo T, Yang N et al (2013) Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels. Nat Genet 45(1):43-50.
-
(2013)
Nat Genet
, vol.45
, Issue.1
, pp. 43-50
-
-
Li, H.1
Peng, Z.2
Yang, X.3
Wang, W.4
Fu, J.5
Wang, J.6
Han, Y.7
Chai, Y.8
Guo, T.9
Yang, N.10
-
98
-
-
67651108806
-
The genetics of quantitative traits: Challenges and prospects
-
Mackay TF, Stone EA, Ayroles JF (2009) The genetics of quantitative traits: challenges and prospects. Nat Rev Genet 10(8):565-577.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.8
, pp. 565-577
-
-
MacKay, T.F.1
Stone, E.A.2
Ayroles, J.F.3
-
99
-
-
40849089396
-
Genetic design and statistical power of nested association mapping in maize
-
Yu J, Holland JB, McMullen MD, Buckler ES (2008) Genetic design and statistical power of nested association mapping in maize. Genetics 178(1):539-551.
-
(2008)
Genetics
, vol.178
, Issue.1
, pp. 539-551
-
-
Yu, J.1
Holland, J.B.2
McMullen, M.D.3
Buckler, E.S.4
-
100
-
-
79251575784
-
Genome-wide association study of quantitative resistance to southern leaf blight in the maize nested association mapping population
-
Kump KL, Bradbury PJ, Wisser RJ, Buckler ES, Belcher AR, Oropeza-Rosas MA, Zwonitzer JC, Kresovich S, McMullen MD, Ware D et al (2011) Genome-wide association study of quantitative resistance to southern leaf blight in the maize nested association mapping population. Nat Genet 43(2):163-168.
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 163-168
-
-
Kump, K.L.1
Bradbury, P.J.2
Wisser, R.J.3
Buckler, E.S.4
Belcher, A.R.5
Oropeza-Rosas, M.A.6
Zwonitzer, J.C.7
Kresovich, S.8
McMullen, M.D.9
Ware, D.10
-
101
-
-
41149121474
-
From mutations toMAGIC: Resources for gene discovery, validation and delivery in crop plants
-
Cavanagh C, Morell M, Mackay I, Powell W(2008) From mutations toMAGIC: resources for gene discovery, validation and delivery in crop plants. Curr Opin Plant Biol 11(2):215-221.
-
(2008)
Curr Opin Plant Biol
, vol.11
, Issue.2
, pp. 215-221
-
-
Cavanagh, C.1
Morell, M.2
MacKay, I.3
Powell, W.4
-
102
-
-
68249120152
-
A multiparent advanced generation inter-cross to fine-map quantitative traits in Arabidopsis thaliana
-
Kover PX, Valdar W, Trakalo J, Scarcelli N, Ehrenreich IM, Purugganan MD, Durrant C, Mott R (2009) A multiparent advanced generation inter-cross to fine-map quantitative traits in Arabidopsis thaliana. PLoS Genet 5(7):e1000551.
-
(2009)
Plos Genet
, vol.5
, Issue.7
-
-
Kover, P.X.1
Valdar, W.2
Trakalo, J.3
Scarcelli, N.4
Ehrenreich, I.M.5
Purugganan, M.D.6
Durrant, C.7
Mott, R.8
-
103
-
-
49849087040
-
Breeding designs for recombinant inbred advanced intercross lines
-
Rockman MV, Kruglyak L (2008) Breeding designs for recombinant inbred advanced intercross lines. Genetics 179(2):1069-1078.
-
(2008)
Genetics
, vol.179
, Issue.2
, pp. 1069-1078
-
-
Rockman, M.V.1
Kruglyak, L.2
-
104
-
-
84887212422
-
QTL mapping in new Arabidopsis thaliana advanced intercross-recombinant inbred lines
-
Balasubramanian S, Schwartz C, Singh A, Warthmann N, Kim MC, Maloof JN, Loudet O, Trainer GT, Dabi T, Borevitz JO et al (2009) QTL mapping in new Arabidopsis thaliana advanced intercross-recombinant inbred lines. PLoS One 4(2):e4318.
-
(2009)
Plos One
, vol.4
, Issue.2
-
-
Balasubramanian, S.1
Schwartz, C.2
Singh, A.3
Warthmann, N.4
Kim, M.C.5
Maloof, J.N.6
Loudet, O.7
Trainer, G.T.8
Dabi, T.9
Borevitz, J.O.10
-
105
-
-
77951987956
-
Genomic selection in plant breeding: From theory to practice
-
Jannink JL, Lorenz AJ, Iwata H (2010) Genomic selection in plant breeding: from theory to practice. Brief Funct Genomics 9(2):166-177.
-
(2010)
Brief Funct Genomics
, vol.9
, Issue.2
, pp. 166-177
-
-
Jannink, J.L.1
Lorenz, A.J.2
Iwata, H.3
-
106
-
-
79952102682
-
Population genetics of genomics-based crop improvement methods
-
Hamblin MT, Buckler ES, Jannink JL (2011) Population genetics of genomics-based crop improvement methods. Trends Genet 27(3):98-106.
-
(2011)
Trends Genet
, vol.27
, Issue.3
, pp. 98-106
-
-
Hamblin, M.T.1
Buckler, E.S.2
Jannink, J.L.3
-
107
-
-
20044390368
-
DNA methylation profiling of the human major histocompatibility complex: A pilot study for the human epigenome project
-
Rakyan VK, Hildmann T, Novik KL, Lewin J, Tost J, Cox AV, Andrews TD, Howe KL, Otto T, Olek A et al (2004) DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project. PLoS Biol 2(12):e405.
-
(2004)
Plos Biol
, vol.2
, Issue.12
-
-
Rakyan, V.K.1
Hildmann, T.2
Novik, K.L.3
Lewin, J.4
Tost, J.5
Cox, A.V.6
Rews, T.D.7
Howe, K.L.8
Otto, T.9
Olek, A.10
-
108
-
-
77953469917
-
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
-
Petronis A (2010) Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature 465(7299):721-727.
-
(2010)
Nature
, vol.465
, Issue.7299
, pp. 721-727
-
-
Petronis, A.1
-
109
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, Heine-Suner D, Cigudosa JC, Urioste M, Benitez J et al (2005) Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A 102(30):10604-10609.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.30
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
Ropero, S.4
Setien, F.5
Ballestar, M.L.6
Heine-Suner, D.7
Cigudosa, J.C.8
Urioste, M.9
Benitez, J.10
-
110
-
-
75649151209
-
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
-
Javierre BM, Fernandez AF, Richter J, Al-Shahrour F, Martin-Subero JI, Rodriguez-Ubreva J, Berdasco M, Fraga MF, O’Hanlon TP, Rider LG et al (2010) Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res 20(2):170-179.
-
(2010)
Genome Res
, vol.20
, Issue.2
, pp. 170-179
-
-
Javierre, B.M.1
Fernandez, A.F.2
Richter, J.3
Al-Shahrour, F.4
Martin-Subero, J.I.5
Rodriguez-Ubreva, J.6
Berdasco, M.7
Fraga, M.F.8
O’Hanlon, T.P.9
Rider, L.G.10
-
111
-
-
77955803943
-
Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain
-
Nguyen A, Rauch TA, Pfeifer GP, Hu VW(2010) Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain. Fed Am Soc Exp Biol 24(8):3036-3051.
-
(2010)
Fed am Soc Exp Biol
, vol.24
, Issue.8
, pp. 3036-3051
-
-
Nguyen, A.1
Rauch, T.A.2
Pfeifer, G.P.3
Hu, V.W.4
-
112
-
-
77953223693
-
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
-
Gibbs JR, van der Brug MP, Hernandez DG, Traynor BJ, Nalls MA, Lai SL, Arepalli S, Dillman A, Rafferty IP, Troncoso J et al (2010) Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet 6(5):e1000952.
-
(2010)
Plos Genet
, vol.6
, Issue.5
-
-
Gibbs, J.R.1
Van Der Brug, M.P.2
Hernandez, D.G.3
Traynor, B.J.4
Nalls, M.A.5
Lai, S.L.6
Arepalli, S.7
Dillman, A.8
Rafferty, I.P.9
Troncoso, J.10
-
113
-
-
77954238686
-
Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome
-
Shoemaker R, Deng J, Wang W, Zhang K (2010) Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome. Genome Res 20(7):883-889.
-
(2010)
Genome Res
, vol.20
, Issue.7
, pp. 883-889
-
-
Shoemaker, R.1
Deng, J.2
Wang, W.3
Zhang, K.4
-
114
-
-
78651552406
-
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
-
Bell JT, Pai AA, Pickrell JK, Gaffney DJ, Pique-Regi R, Degner JF, Gilad Y, Pritchard JK (2011) DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol 12(1):R10.
-
(2011)
Genome Biol
, vol.12
, Issue.1
-
-
Bell, J.T.1
Pai, A.A.2
Pickrell, J.K.3
Gaffney, D.J.4
Pique-Regi, R.5
Degner, J.F.6
Gilad, Y.7
Pritchard, J.K.8
-
115
-
-
84860572791
-
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
-
Bell JT, Tsai PC, Yang TP, Pidsley R, Nisbet J, Glass D, Mangino M, Zhai G, Zhang F, Valdes A et al (2012) Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet 8(4):e1002629.
-
(2012)
Plos Genet 8(4)
-
-
Bell, J.T.1
Tsai, P.C.2
Yang, T.P.3
Pidsley, R.4
Nisbet, J.5
Glass, D.6
Mangino, M.7
Zhai, G.8
Zhang, F.9
Valdes, A.10
-
116
-
-
77649204292
-
Genetic control of individual differences in gene-specific methylation in human brain
-
Zhang D, Cheng L, Badner JA, Chen C, Chen Q, Luo W, Craig DW, Redman M, Gershon ES, Liu C (2010) Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet 86(3):411-419.
-
(2010)
Am J Hum Genet
, vol.86
, Issue.3
, pp. 411-419
-
-
Zhang, D.1
Cheng, L.2
Badner, J.A.3
Chen, C.4
Chen, Q.5
Luo, W.6
Craig, D.W.7
Redman, M.8
Gershon, E.S.9
Liu, C.10
-
117
-
-
84867133601
-
Genetic and epigenetic contribution to complex traits
-
Kilpinen H, Dermitzakis ET (2012) Genetic and epigenetic contribution to complex traits. Hum Mol Genet 21(R1):R24-R28.
-
(2012)
Hum Mol Genet
, vol.21
, Issue.R1
-
-
Kilpinen, H.1
Dermitzakis, E.T.2
-
118
-
-
34347327677
-
Epigenetic natural variation in Arabidopsis thaliana
-
Vaughn MW, Tanurdzic M, Lippman Z, Jiang H, Carrasquillo R, Rabinowicz PD, Dedhia N, McCombie WR, Agier N, Bulski A et al (2007) Epigenetic natural variation in Arabidopsis thaliana. PLoS Biol 5(7):e174.
-
(2007)
Plos Biol
, vol.5
, Issue.7
-
-
Vaughn, M.W.1
Tanurdzic, M.2
Lippman, Z.3
Jiang, H.4
Carrasquillo, R.5
Rabinowicz, P.D.6
Dedhia, N.7
McCombie, W.R.8
Agier, N.9
Bulski, A.10
-
119
-
-
80054718602
-
Spontaneous epigenetic variation in the Arabidopsis thaliana methylome
-
Becker C, Hagmann J, Muller J, Koenig D, Stegle O, Borgwardt K, Weigel D (2011) Spontaneous epigenetic variation in the Arabidopsis thaliana methylome. Nature 480(7376):245-249.
-
(2011)
Nature
, vol.480
, Issue.7376
, pp. 245-249
-
-
Becker, C.1
Hagmann, J.2
Muller, J.3
Koenig, D.4
Stegle, O.5
Borgwardt, K.6
Weigel, D.7
-
120
-
-
81755163109
-
Heritable epigenetic variation among maize inbreds
-
Eichten SR, Swanson-Wagner RA, Schnable JC, Waters AJ, Hermanson PJ, Liu S, Yeh CT, Jia Y, Gendler K, Freeling M et al (2011) Heritable epigenetic variation among maize inbreds. PLoS Genet 7(11):e1002372.
-
(2011)
Plos Genet
, vol.7
, Issue.11
-
-
Eichten, S.R.1
Swanson-Wagner, R.A.2
Schnable, J.C.3
Waters, A.J.4
Hermanson, P.J.5
Liu, S.6
Yeh, C.T.7
Jia, Y.8
Gendler, K.9
Freeling, M.10
-
121
-
-
84864353941
-
Transcriptome and methylome interactions in rice hybrids
-
Chodavarapu RK, Feng S, Ding B, Simon SA, Lopez D, Jia Y, Wang GL, Meyers BC, Jacobsen SE, Pellegrini M (2012) Transcriptome and methylome interactions in rice hybrids. Proc Natl Acad Sci U S A 109(30):12040-12045.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.30
, pp. 12040-12045
-
-
Chodavarapu, R.K.1
Feng, S.2
Ding, B.3
Simon, S.A.4
Lopez, D.5
Jia, Y.6
Wang, G.L.7
Meyers, B.C.8
Jacobsen, S.E.9
Pellegrini, M.10
-
122
-
-
84855268714
-
Natural variation in Arabidopsis: From molecular genetics to ecological genomics
-
Weigel D (2012) Natural variation in Arabidopsis: from molecular genetics to ecological genomics. Plant Physiol 158(1):2-22.
-
(2012)
Plant Physiol
, vol.158
, Issue.1
, pp. 2-22
-
-
Weigel, D.1
-
123
-
-
60349092402
-
Mapping complex disease traits with global gene expression
-
Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M (2009) Mapping complex disease traits with global gene expression. Nat Rev Genet 10(3):184-194.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.3
, pp. 184-194
-
-
Cookson, W.1
Liang, L.2
Abecasis, G.3
Moffatt, M.4
Lathrop, M.5
-
124
-
-
19544378364
-
Methodological aspects of the genetic dissection of gene expression
-
Carlborg O, De Koning DJ, Manly KF, Chesler E, Williams RW, Haley CS (2005) Methodological aspects of the genetic dissection of gene expression. Bioinformatics 21(10):2383-2393.
-
(2005)
Bioinformatics
, vol.21
, Issue.10
, pp. 2383-2393
-
-
Carlborg, O.1
De Koning, D.J.2
Manly, K.F.3
Chesler, E.4
Williams, R.W.5
Haley, C.S.6
-
125
-
-
34548805282
-
A genome-wide association study of global gene expression
-
Dixon AL, Liang L, Moffatt MF, Chen W, Heath S, Wong KC, Taylor J, Burnett E, Gut I, Farrall M et al (2007) A genome-wide association study of global gene expression. Nat Genet 39(10):1202-1207.
-
(2007)
Nat Genet
, vol.39
, Issue.10
, pp. 1202-1207
-
-
Dixon, A.L.1
Liang, L.2
Moffatt, M.F.3
Chen, W.4
Heath, S.5
Wong, K.C.6
Taylor, J.7
Burnett, E.8
Gut, I.9
Farrall, M.10
-
126
-
-
55449112450
-
High-resolution mapping of expression-QTLs yields insight into human gene regulation
-
Veyrieras JB, Kudaravalli S, Kim SY, Dermitzakis ET, Gilad Y, Stephens M, Pritchard JK (2008) High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet 4(10):e1000214.
-
(2008)
Plos Genet
, vol.4
, Issue.10
-
-
Veyrieras, J.B.1
Kudaravalli, S.2
Kim, S.Y.3
Dermitzakis, E.T.4
Gilad, Y.5
Stephens, M.6
Pritchard, J.K.7
-
127
-
-
77952918274
-
Genetic variation in microRNA networks: The implications for cancer research
-
Ryan BM, Robles AI, Harris CC (2010) Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 10(6):389-402.
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.6
, pp. 389-402
-
-
Ryan, B.M.1
Robles, A.I.2
Harris, C.C.3
-
128
-
-
84876394432
-
Patterns of methylation heritability in a genome-wide analysis of four brain regions
-
Quon G, Lippert C, Heckerman D, Listgarten J (2013) Patterns of methylation heritability in a genome-wide analysis of four brain regions. Nucleic Acids Res 41(4):2095-2104.
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.4
, pp. 2095-2104
-
-
Quon, G.1
Lippert, C.2
Heckerman, D.3
Listgarten, J.4
-
129
-
-
41349095280
-
Genetics of gene expression and its effect on disease
-
Emilsson V, Thorleifsson G, Zhang B, Leonardson AS, Zink F, Zhu J, Carlson S, Helgason A, Walters GB, Gunnarsdottir S et al (2008) Genetics of gene expression and its effect on disease. Nature 452(7186):423-428.
-
(2008)
Nature
, vol.452
, Issue.7186
, pp. 423-428
-
-
Emilsson, V.1
Thorleifsson, G.2
Zhang, B.3
Leonardson, A.S.4
Zink, F.5
Zhu, J.6
Carlson, S.7
Helgason, A.8
Walters, G.B.9
Gunnarsdottir, S.10
-
130
-
-
35648969195
-
Genetic basis of proteome variation in yeast
-
Foss EJ, Radulovic D, Shaffer SA, Ruderfer DM, Bedalov A, Goodlett DR, Kruglyak L (2007) Genetic basis of proteome variation in yeast. Nat Genet 39(11):1369-1375.
-
(2007)
Nat Genet
, vol.39
, Issue.11
, pp. 1369-1375
-
-
Foss, E.J.1
Radulovic, D.2
Shaffer, S.A.3
Ruderfer, D.M.4
Bedalov, A.5
Goodlett, D.R.6
Kruglyak, L.7
-
131
-
-
0028285005
-
Quantitative trait loci underlying gene product variation: A novel perspective for analyzing regulation of genome expression
-
Damerval C, Maurice A, Josse JM, de Vienne D (1994) Quantitative trait loci underlying gene product variation: a novel perspective for analyzing regulation of genome expression. Genetics 137(1):289-301.
-
(1994)
Genetics
, vol.137
, Issue.1
, pp. 289-301
-
-
Damerval, C.1
Maurice, A.2
Josse, J.M.3
De Vienne, D.4
-
132
-
-
84873724658
-
A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis
-
Picotti P, Clement-Ziza M, Lam H, Campbell DS, Schmidt A, Deutsch EW, Rost H, Sun Z, Rinner O, Reiter L et al (2013) A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis. Nature 494(7436):266-270.
-
(2013)
Nature
, vol.494
, Issue.7436
, pp. 266-270
-
-
Picotti, P.1
Clement-Ziza, M.2
Lam, H.3
Campbell, D.S.4
Schmidt, A.5
Deutsch, E.W.6
Rost, H.7
Sun, Z.8
Rinner, O.9
Reiter, L.10
-
133
-
-
68949206409
-
Applying mass spectrometry-based proteomics to genetics, genomics and network biology
-
Gstaiger M, Aebersold R (2009) Applying mass spectrometry-based proteomics to genetics, genomics and network biology. Nat Rev Genet 10(9):617-627.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.9
, pp. 617-627
-
-
Gstaiger, M.1
Aebersold, R.2
-
134
-
-
79959812980
-
Comparative analysis of proteome and transcriptome variation in mouse
-
Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N et al (2011) Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet 7(6):e1001393.
-
(2011)
Plos Genet 7(6)
-
-
Ghazalpour, A.1
Bennett, B.2
Petyuk, V.A.3
Orozco, L.4
Hagopian, R.5
Mungrue, I.N.6
Farber, C.R.7
Sinsheimer, J.8
Kang, H.M.9
Furlotte, N.10
-
135
-
-
62349101060
-
Genetical metabolomics: Closing in on phenotypes
-
Keurentjes JJ (2009) Genetical metabolomics: closing in on phenotypes. Curr Opin Plant Biol 12(2):223-230.
-
(2009)
Curr Opin Plant Biol
, vol.12
, Issue.2
, pp. 223-230
-
-
Keurentjes, J.J.1
-
136
-
-
84867744660
-
Genetic variation in metabolic phenotypes: Study designs and applications
-
Suhre K, Gieger C (2012) Genetic variation in metabolic phenotypes: study designs and applications. Nat Rev Genet 13(11):759-769.
-
(2012)
Nat Rev Genet
, vol.13
, Issue.11
, pp. 759-769
-
-
Suhre, K.1
Gieger, C.2
-
138
-
-
84861875050
-
Genome-wide association mapping of leaf metabolic profiles for dissecting complex traits in maize
-
Riedelsheimer C, Lisec J, Czedik-Eysenberg A, Sulpice R, Flis A, Grieder C, Altmann T, Stitt M, Willmitzer L, Melchinger AE (2012) Genome-wide association mapping of leaf metabolic profiles for dissecting complex traits in maize. Proc Natl Acad Sci U S A 109(23):8872-8877.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.23
, pp. 8872-8877
-
-
Riedelsheimer, C.1
Lisec, J.2
Czedik-Eysenberg, A.3
Sulpice, R.4
Flis, A.5
Grieder, C.6
Altmann, T.7
Stitt, M.8
Willmitzer, L.9
Melchinger, A.E.10
-
139
-
-
33645746673
-
Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement
-
Schauer N, Semel Y, Roessner U, Gur A, Balbo I, Carrari F, Pleban T, Perez-Melis A, Bruedigam C, Kopka J et al (2006) Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement. Nat Biotechnol 24(4):447-454.
-
(2006)
Nat Biotechnol
, vol.24
, Issue.4
, pp. 447-454
-
-
Schauer, N.1
Semel, Y.2
Roessner, U.3
Gur, A.4
Balbo, I.5
Carrari, F.6
Pleban, T.7
Perez-Melis, A.8
Bruedigam, C.9
Kopka, J.10
-
140
-
-
33644915864
-
Identification of loci affecting flavour volatile emissions in tomato fruits
-
Tieman DM, Zeigler M, Schmelz EA, Taylor MG, Bliss P, Kirst M, Klee HJ (2006) Identification of loci affecting flavour volatile emissions in tomato fruits. J Exp Bot 57(4):887-896.
-
(2006)
J Exp Bot
, vol.57
, Issue.4
, pp. 887-896
-
-
Tieman, D.M.1
Zeigler, M.2
Schmelz, E.A.3
Taylor, M.G.4
Bliss, P.5
Kirst, M.6
Klee, H.J.7
-
141
-
-
48249152281
-
Mode of inheritance of primary metabolic traits in tomato
-
Schauer N, Semel Y, Balbo I, Steinfath M, Repsilber D, Selbig J, Pleban T, Zamir D, Fernie AR (2008) Mode of inheritance of primary metabolic traits in tomato. Plant Cell 20(3): 509-523.
-
(2008)
Plant Cell
, vol.20
, Issue.3
, pp. 509-523
-
-
Schauer, N.1
Semel, Y.2
Balbo, I.3
Steinfath, M.4
Repsilber, D.5
Selbig, J.6
Pleban, T.7
Zamir, D.8
Fernie, A.R.9
-
142
-
-
77956429710
-
Discovering plant metabolic biomarkers for phenotype prediction using an untargeted approach
-
Steinfath M, Strehmel N, Peters R, Schauer N, Groth D, Hummel J, Steup M, Selbig J, Kopka J, Geigenberger P et al (2010) Discovering plant metabolic biomarkers for phenotype prediction using an untargeted approach. Plant Biotechnol J 8(8):900-911.
-
(2010)
Plant Biotechnol J
, vol.8
, Issue.8
, pp. 900-911
-
-
Steinfath, M.1
Strehmel, N.2
Peters, R.3
Schauer, N.4
Groth, D.5
Hummel, J.6
Steup, M.7
Selbig, J.8
Kopka, J.9
Geigenberger, P.10
-
143
-
-
34248377833
-
The metabolic signature related to high plant growth rate in Arabidopsis thaliana
-
Meyer RC, Steinfath M, Lisec J, Becher M, Witucka-Wall H, Torjek O, Fiehn O, Eckardt A, Willmitzer L, Selbig J et al (2007) The metabolic signature related to high plant growth rate in Arabidopsis thaliana. Proc Natl Acad Sci U S A 104(11):4759-4764.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.11
, pp. 4759-4764
-
-
Meyer, R.C.1
Steinfath, M.2
Lisec, J.3
Becher, M.4
Witucka-Wall, H.5
Torjek, O.6
Fiehn, O.7
Eckardt, A.8
Willmitzer, L.9
Selbig, J.10
-
144
-
-
33745580270
-
The genetics of plant metabolism
-
Keurentjes JJ, Fu J, de Vos CH, Lommen A, Hall RD, Bino RJ, van der Plas LH, Jansen RC, Vreugdenhil D, Koornneef M(2006) The genetics of plant metabolism. Nat Genet 38(7): 842-849.
-
(2006)
Nat Genet
, vol.38
, Issue.7
, pp. 842-849
-
-
Keurentjes, J.J.1
Fu, J.2
De Vos, C.H.3
Lommen, A.4
Hall, R.D.5
Bino, R.J.6
Van Der Plas, L.H.7
Jansen, R.C.8
Vreugdenhil, D.9
Koornneef, M.10
-
145
-
-
40549123412
-
Identification of metabolic and biomass QTL in Arabidopsis thaliana in a parallel analysis of RIL and IL populations
-
Lisec J, Meyer RC, Steinfath M, Redestig H, Becher M, Witucka-Wall H, Fiehn O, Torjek O, Selbig J, Altmann T et al (2008) Identification of metabolic and biomass QTL in Arabidopsis thaliana in a parallel analysis of RIL and IL populations. Plant J Cell Mol Biol 53(6):960-972.
-
(2008)
Plant J Cell Mol Biol
, vol.53
, Issue.6
, pp. 960-972
-
-
Lisec, J.1
Meyer, R.C.2
Steinfath, M.3
Redestig, H.4
Becher, M.5
Witucka-Wall, H.6
Fiehn, O.7
Torjek, O.8
Selbig, J.9
Altmann, T.10
-
146
-
-
69249145607
-
Identification of heterotic metabolite QTL in Arabidopsis thaliana RIL and IL populations
-
Lisec J, Steinfath M, Meyer RC, Selbig J, Melchinger AE, Willmitzer L, Altmann T (2009) Identification of heterotic metabolite QTL in Arabidopsis thaliana RIL and IL populations. Plant J Cell Mol Biol 59(5):777-788.
-
(2009)
Plant J Cell Mol Biol
, vol.59
, Issue.5
, pp. 777-788
-
-
Lisec, J.1
Steinfath, M.2
Meyer, R.C.3
Selbig, J.4
Melchinger, A.E.5
Willmitzer, L.6
Altmann, T.7
-
147
-
-
54149090305
-
Biochemical networks and epistasis shape the Arabidopsis thaliana metabolome
-
Rowe HC, Hansen BG, Halkier BA, Kliebenstein DJ (2008) Biochemical networks and epistasis shape the Arabidopsis thaliana metabolome. Plant Cell 20(5):1199-1216.
-
(2008)
Plant Cell
, vol.20
, Issue.5
, pp. 1199-1216
-
-
Rowe, H.C.1
Hansen, B.G.2
Halkier, B.A.3
Kliebenstein, D.J.4
-
148
-
-
44949175103
-
KoornneefM, Bonnema G
-
Lou P, Zhao J, He H, Hanhart C, Del Carpio DP, Verkerk R, Custers J, KoornneefM, Bonnema G (2008) Quantitative trait loci for glucosinolate accumulation in Brassica rapa leaves. New Phytol 179(4):1017-1032.
-
(2008)
Quantitative Trait Loci for Glucosinolate Accumulation in Brassica Rapa Leaves. New Phytol
, vol.179
, Issue.4
, pp. 1017-1032
-
-
Lou, P.1
Zhao, J.2
He, H.3
Hanhart, C.4
Del Carpio, D.P.5
Verkerk, R.6
Custers, J.7
-
149
-
-
82955237367
-
Characterization of metabolite quantitative trait loci and metabolic networks that control glucosinolate concentration in the seeds and leaves of Brassica napus
-
Feng J, Long Y, Shi L, Shi J, Barker G, Meng J (2012) Characterization of metabolite quantitative trait loci and metabolic networks that control glucosinolate concentration in the seeds and leaves of Brassica napus. New Phytol 193(1):96-108.
-
(2012)
New Phytol
, vol.193
, Issue.1
, pp. 96-108
-
-
Feng, J.1
Long, Y.2
Shi, L.3
Shi, J.4
Barker, G.5
Meng, J.6
-
150
-
-
84857966782
-
Untargeted metabolic quantitative trait loci analyses reveal a relationship between primary metabolism and potato tuber quality
-
Carreno-Quintero N, Acharjee A, Maliepaard C, Bachem CW, Mumm R, Bouwmeester H, Visser RG, Keurentjes JJ (2012) Untargeted metabolic quantitative trait loci analyses reveal a relationship between primary metabolism and potato tuber quality. Plant Physiol 158(3):1306-1318.
-
(2012)
Plant Physiol
, vol.158
, Issue.3
, pp. 1306-1318
-
-
Carreno-Quintero, N.1
Acharjee, A.2
Maliepaard, C.3
Bachem, C.W.4
Mumm, R.5
Bouwmeester, H.6
Visser, R.G.7
Keurentjes, J.J.8
-
151
-
-
84861337100
-
Dissection of genotype-phenotype associations in rice grains using metabolome quantitative trait loci analysis
-
Matsuda F, Okazaki Y, Oikawa A, Kusano M, Nakabayashi R, Kikuchi J, Yonemaru J, Ebana K, Yano M, Saito K (2012) Dissection of genotype-phenotype associations in rice grains using metabolome quantitative trait loci analysis. Plant J Cell Mol Biol 70(4):624-636.
-
(2012)
Plant J Cell Mol Biol
, vol.70
, Issue.4
, pp. 624-636
-
-
Matsuda, F.1
Okazaki, Y.2
Oikawa, A.3
Kusano, M.4
Nakabayashi, R.5
Kikuchi, J.6
Yonemaru, J.7
Ebana, K.8
Yano, M.9
Saito, K.10
-
152
-
-
84856283792
-
Genomic and metabolic prediction of complex heterotic traits in hybrid maize
-
Riedelsheimer C, Czedik-Eysenberg A, Grieder C, Lisec J, Technow F, Sulpice R, Altmann T, Stitt M, Willmitzer L, Melchinger AE (2012) Genomic and metabolic prediction of complex heterotic traits in hybrid maize. Nat Genet 44(2):217-220.
-
(2012)
Nat Genet
, vol.44
, Issue.2
, pp. 217-220
-
-
Riedelsheimer, C.1
Czedik-Eysenberg, A.2
Grieder, C.3
Lisec, J.4
Technow, F.5
Sulpice, R.6
Altmann, T.7
Stitt, M.8
Willmitzer, L.9
Melchinger, A.E.10
-
153
-
-
58149330201
-
Metabolomics-assisted breeding: A viable option for crop improvement?
-
Fernie AR, Schauer N (2009) Metabolomics-assisted breeding: a viable option for crop improvement? Trends Genet 25(1):39-48.
-
(2009)
Trends Genet
, vol.25
, Issue.1
, pp. 39-48
-
-
Fernie, A.R.1
Schauer, N.2
-
154
-
-
57149114936
-
Genetics meets metabolomics: A genome-wide association study of metabolite profiles in human serum
-
Gieger C, Geistlinger L, Altmaier E, Hrabe de Angelis M, Kronenberg F, Meitinger T, Mewes HW, Wichmann HE, Weinberger KM, Adamski J et al (2008) Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet 4(11):e1000282.
-
(2008)
Plos Genet
, vol.4
, Issue.11
-
-
Gieger, C.1
Geistlinger, L.2
Altmaier, E.3
De Hrabe Angelis, M.4
Kronenberg, F.5
Meitinger, T.6
Mewes, H.W.7
Wichmann, H.E.8
Weinberger, K.M.9
Adamski, J.10
-
155
-
-
75749134031
-
A genome-wide perspective of genetic variation in human metabolism
-
Illig T, Gieger C, Zhai G, Romisch-Margl W, Wang-Sattler R, Prehn C, Altmaier E, Kastenmuller G, Kato BS, Mewes HW et al (2010) A genome-wide perspective of genetic variation in human metabolism. Nat Genet 42(2):137-141.
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 137-141
-
-
Illig, T.1
Gieger, C.2
Zhai, G.3
Romisch-Margl, W.4
Wang-Sattler, R.5
Prehn, C.6
Altmaier, E.7
Kastenmuller, G.8
Kato, B.S.9
Mewes, H.W.10
-
156
-
-
80052398214
-
Human metabolic individuality in biomedical and pharmaceutical research
-
Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wagele B, Altmaier E, Cardio-Gram, Deloukas P, Erdmann J et al (2011) Human metabolic individuality in biomedical and pharmaceutical research. Nature 477(7362):54-60.
-
(2011)
Nature
, vol.477
, Issue.7362
, pp. 54-60
-
-
Suhre, K.1
Shin, S.Y.2
Petersen, A.K.3
Mohney, R.P.4
Meredith, D.5
Wagele, B.6
Altmaier, E.7
Cardio-Gram, D.P.8
Erdmann, J.9
-
157
-
-
84857648463
-
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
-
Kettunen J, Tukiainen T, Sarin AP, Ortega-Alonso A, Tikkanen E, Lyytikainen LP, Kangas AJ, Soininen P, Wurtz P, Silander K et al (2012) Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat Genet 44(3):269-276.
-
(2012)
Nat Genet
, vol.44
, Issue.3
, pp. 269-276
-
-
Kettunen, J.1
Tukiainen, T.2
Sarin, A.P.3
Ortega-Alonso, A.4
Tikkanen, E.5
Lyytikainen, L.P.6
Kangas, A.J.7
Soininen, P.8
Wurtz, P.9
Silander, K.10
-
158
-
-
43749087841
-
Human metabolic phenotype diversity and its association with diet and blood pressure
-
Holmes E, Loo RL, Stamler J, Bictash M, Yap IK, Chan Q, Ebbels T, De Iorio M, Brown IJ, Veselkov KA et al (2008) Human metabolic phenotype diversity and its association with diet and blood pressure. Nature 453(7193):396-400.
-
(2008)
Nature
, vol.453
, Issue.7193
, pp. 396-400
-
-
Holmes, E.1
Loo, R.L.2
Stamler, J.3
Bictash, M.4
Yap, I.K.5
Chan, Q.6
Ebbels, T.7
De Iorio, M.8
Brown, I.J.9
Veselkov, K.A.10
-
159
-
-
77953667219
-
Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events
-
Shah SH, Bain JR, Muehlbauer MJ, Stevens RD, Crosslin DR, Haynes C, Dungan J, Newby LK, Hauser ER, Ginsburg GS et al (2010) Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet 3(2):207-214.
-
(2010)
Circ Cardiovasc Genet
, vol.3
, Issue.2
, pp. 207-214
-
-
Shah, S.H.1
Bain, J.R.2
Muehlbauer, M.J.3
Stevens, R.D.4
Crosslin, D.R.5
Haynes, C.6
Dungan, J.7
Newby, L.K.8
Hauser, E.R.9
Ginsburg, G.S.10
-
160
-
-
0035400051
-
Genetical genomics: The added value from segregation
-
Jansen RC, Nap JP (2001) Genetical genomics: the added value from segregation. Trends Genet 17(7):388-391.
-
(2001)
Trends Genet
, vol.17
, Issue.7
, pp. 388-391
-
-
Jansen, R.C.1
Nap, J.P.2
-
161
-
-
20644454887
-
Genetical genomics in humans and model organisms
-
de Koning DJ, Haley CS (2005) Genetical genomics in humans and model organisms. Trends Genet 21(7):377-381.
-
(2005)
Trends Genet
, vol.21
, Issue.7
, pp. 377-381
-
-
De Koning, D.J.1
Haley, C.S.2
-
162
-
-
59149100506
-
System-wide molecular evidence for phenotypic buffering in Arabidopsis
-
Fu J, Keurentjes JJ, Bouwmeester H, America T, Verstappen FW, Ward JL, Beale MH, de Vos RC, Dijkstra M, Scheltema RA et al (2009) System-wide molecular evidence for phenotypic buffering in Arabidopsis. Nat Genet 41(2):166-167.
-
(2009)
Nat Genet
, vol.41
, Issue.2
, pp. 166-167
-
-
Fu, J.1
Keurentjes, J.J.2
Bouwmeester, H.3
America, T.4
Verstappen, F.W.5
Ward, J.L.6
Beale, M.H.7
De Vos, R.C.8
Dijkstra, M.9
Scheltema, R.A.10
-
164
-
-
84858433310
-
Personal omics profiling reveals dynamic molecular and medical phenotypes
-
Chen R, Mias GI, Li-Pook-Than J, Jiang L, Lam HY, Chen R, Miriami E, Karczewski KJ, Hariharan M, Dewey FE et al (2012) Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell 148(6):1293-1307.
-
(2012)
Cell
, vol.148
, Issue.6
, pp. 1293-1307
-
-
Chen, R.1
Mias, G.I.2
Li-Pook-than, J.3
Jiang, L.4
Lam, H.Y.5
Chen, R.6
Miriami, E.7
Karczewski, K.J.8
Hariharan, M.9
Dewey, F.E.10
-
165
-
-
34547140875
-
The human disease network
-
Goh KI, Cusick ME, Valle D, Childs B, Vidal M, Barabasi AL (2007) The human disease network. Proc Natl Acad Sci U S A 104(21):8685-8690.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.21
, pp. 8685-8690
-
-
Goh, K.I.1
Cusick, M.E.2
Valle, D.3
Childs, B.4
Vidal, M.5
Barabasi, A.L.6
-
166
-
-
43249114206
-
Network-based global inference of human disease genes
-
Wu X, Jiang R, Zhang MQ, Li S (2008) Network-based global inference of human disease genes. Mol Syst Biol 4:189.
-
(2008)
Mol Syst Biol
, vol.4
, pp. 189
-
-
Wu, X.1
Jiang, R.2
Zhang, M.Q.3
Li, S.4
-
167
-
-
33749335282
-
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
-
Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet JP, Subramanian A, Ross KN et al (2006) The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313(5795):1929-1935.
-
(2006)
Science
, vol.313
, Issue.5795
, pp. 1929-1935
-
-
Lamb, J.1
Crawford, E.D.2
Peck, D.3
Modell, J.W.4
Blat, I.C.5
Wrobel, M.J.6
Lerner, J.7
Brunet, J.P.8
Subramanian, A.9
Ross, K.N.10
-
168
-
-
45949108954
-
Protein interactions in human genetic diseases
-
Schuster-Bockler B, Bateman A (2008) Protein interactions in human genetic diseases. Genome Biol 9(1):R9.
-
(2008)
Genome Biol
, vol.9
, Issue.1
-
-
Schuster-Bockler, B.1
Bateman, A.2
-
169
-
-
77953681096
-
A systems biology approach to understanding atherosclerosis
-
Ramsey SA, Gold ES, Aderem A (2010) A systems biology approach to understanding atherosclerosis. EMBO Mol Med 2(3):79-89.
-
(2010)
EMBO Mol Med
, vol.2
, Issue.3
, pp. 79-89
-
-
Ramsey, S.A.1
Gold, E.S.2
Aderem, A.3
-
170
-
-
78650665228
-
Metabonomic, transcriptomic, and genomic variation of a population cohort
-
Inouye M, Kettunen J, Soininen P, Silander K, Ripatti S, Kumpula LS, Hamalainen E, Jousilahti P, Kangas AJ, Mannisto S et al (2010) Metabonomic, transcriptomic, and genomic variation of a population cohort. Mol Syst Biol 6:441.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 441
-
-
Inouye, M.1
Kettunen, J.2
Soininen, P.3
Silander, K.4
Ripatti, S.5
Kumpula, L.S.6
Hamalainen, E.7
Jousilahti, P.8
Kangas, A.J.9
Mannisto, S.10
-
171
-
-
48249158278
-
The implications of human metabolic network topology for disease comorbidity
-
Lee DS, Park J, Kay KA, Christakis NA, Oltvai ZN, Barabasi AL (2008) The implications of human metabolic network topology for disease comorbidity. Proc Natl Acad Sci U S A 105(29):9880-9885.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.29
, pp. 9880-9885
-
-
Lee, D.S.1
Park, J.2
Kay, K.A.3
Christakis, N.A.4
Oltvai, Z.N.5
Barabasi, A.L.6
-
173
-
-
77953888015
-
Prioritization of disease microRNAs through a human phenome-microRNAome network
-
Jiang Q, Hao Y, Wang G, Juan L, Zhang T, Teng M, Liu Y, Wang Y (2010) Prioritization of disease microRNAs through a human phenome-microRNAome network. BMC Syst Biol 4(Suppl 1):S2.
-
(2010)
BMC Syst Biol
, vol.4
-
-
Jiang, Q.1
Hao, Y.2
Wang, G.3
Juan, L.4
Zhang, T.5
Teng, M.6
Liu, Y.7
Wang, Y.8
-
174
-
-
30544439504
-
Creation and implications of a phenome-genome network
-
Butte AJ, Kohane IS (2006) Creation and implications of a phenome-genome network. Nat Biotechnol 24(1):55-62.
-
(2006)
Nat Biotechnol
, vol.24
, Issue.1
, pp. 55-62
-
-
Butte, A.J.1
Kohane, I.S.2
-
175
-
-
84884594782
-
A global map for dissecting phenotypic variants in human lincRNAs
-
Ning S, Wang P, Ye J, Li X, Li R, Zhao Z, Huo X, Wang L, Li F, Li X (2013) A global map for dissecting phenotypic variants in human lincRNAs. Eur J Hum Genet 21(10):1128-1133.
-
(2013)
Eur J Hum Genet
, vol.21
, Issue.10
, pp. 1128-1133
-
-
Ning, S.1
Wang, P.2
Ye, J.3
Li, X.4
Li, R.5
Zhao, Z.6
Huo, X.7
Wang, L.8
Li, F.9
Li, X.10
-
176
-
-
79959898376
-
Prioritizing candidate disease genes by network-based boosting of genome-wide association data
-
Lee I, Blom UM, Wang PI, Shim JE, Marcotte EM (2011) Prioritizing candidate disease genes by network-based boosting of genome-wide association data. Genome Res 21(7):1109-1121.
-
(2011)
Genome Res
, vol.21
, Issue.7
, pp. 1109-1121
-
-
Lee, I.1
Blom, U.M.2
Wang, P.I.3
Shim, J.E.4
Marcotte, E.M.5
-
177
-
-
33947095027
-
A human phenome-interactome network of protein complexes implicated in genetic disorders
-
Lage K, Karlberg EO, Storling ZM, Olason PI, Pedersen AG, Rigina O, Hinsby AM, Tumer Z, Pociot F, Tommerup N et al (2007) A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol 25(3):309-316.
-
(2007)
Nat Biotechnol
, vol.25
, Issue.3
, pp. 309-316
-
-
Lage, K.1
Karlberg, E.O.2
Storling, Z.M.3
Olason, P.I.4
Pedersen, A.G.5
Rigina, O.6
Hinsby, A.M.7
Tumer, Z.8
Pociot, F.9
Tommerup, N.10
-
178
-
-
56649084972
-
Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks
-
Iliopoulos D, Malizos KN, Oikonomou P, Tsezou A (2008) Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One 3(11):e3740.
-
(2008)
Plos One
, vol.3
, Issue.11
-
-
Iliopoulos, D.1
Malizos, K.N.2
Oikonomou, P.3
Tsezou, A.4
-
179
-
-
35349024501
-
Network modeling links breast cancer susceptibility and centrosome dysfunction
-
Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B et al (2007) Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat Genet 39(11):1338-1349.
-
(2007)
Nat Genet
, vol.39
, Issue.11
, pp. 1338-1349
-
-
Pujana, M.A.1
Han, J.D.2
Starita, L.M.3
Stevens, K.N.4
Tewari, M.5
Ahn, J.S.6
Rennert, G.7
Moreno, V.8
Kirchhoff, T.9
Gold, B.10
-
180
-
-
78650373804
-
Network medicine: A network-based approach to human disease
-
Barabasi AL, Gulbahce N, Loscalzo J (2011) Network medicine: a network-based approach to human disease. Nat Rev Genet 12(1):56-68.
-
(2011)
Nat Rev Genet
, vol.12
, Issue.1
, pp. 56-68
-
-
Barabasi, A.L.1
Gulbahce, N.2
Loscalzo, J.3
-
181
-
-
54849408182
-
An analysis of human microRNA and disease associations
-
Lu M, Zhang Q, Deng M, Miao J, Guo Y, Gao W, Cui Q (2008) An analysis of human microRNA and disease associations. PLoS One 3(10):e3420.
-
(2008)
Plos One
, vol.3
, Issue.10
-
-
Lu, M.1
Zhang, Q.2
Deng, M.3
Miao, J.4
Guo, Y.5
Gao, W.6
Cui, Q.7
-
182
-
-
33747035889
-
Predicting disease genes using proteinprotein interactions
-
Oti M, Snel B, Huynen MA, Brunner HG (2006) Predicting disease genes using proteinprotein interactions. J Med Genet 43(8):691-698.
-
(2006)
J Med Genet
, vol.43
, Issue.8
, pp. 691-698
-
-
Oti, M.1
Snel, B.2
Huynen, M.A.3
Brunner, H.G.4
-
183
-
-
41549139527
-
Walking the interactome for prioritization of candidate disease genes
-
Kohler S, Bauer S, Horn D, Robinson PN (2008) Walking the interactome for prioritization of candidate disease genes. Am J Hum Genet 82(4):949-958.
-
(2008)
Am J Hum Genet
, vol.82
, Issue.4
, pp. 949-958
-
-
Kohler, S.1
Bauer, S.2
Horn, D.3
Robinson, P.N.4
-
184
-
-
76749134818
-
Associating genes and protein complexes with disease via network propagation
-
Vanunu O, Magger O, Ruppin E, Shlomi T, Sharan R (2010) Associating genes and protein complexes with disease via network propagation. PLoS Comput Biol 6(1):e1000641.
-
(2010)
Plos Comput Biol
, vol.6
, Issue.1
-
-
Vanunu, O.1
Magger, O.2
Ruppin, E.3
Shlomi, T.4
Sharan, R.5
-
185
-
-
77950900465
-
Systematic discovery of nonobvious human disease models through orthologous phenotypes
-
McGary KL, Park TJ, Woods JO, Cha HJ, Wallingford JB, Marcotte EM (2010) Systematic discovery of nonobvious human disease models through orthologous phenotypes. Proc Natl Acad Sci U S A 107(14):6544-6549.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.14
, pp. 6544-6549
-
-
McGary, K.L.1
Park, T.J.2
Woods, J.O.3
Cha, H.J.4
Wallingford, J.B.5
Marcotte, E.M.6
-
186
-
-
84870724279
-
Systems analysis of plant functional, transcriptional, physical interaction, and metabolic networks
-
Bassel GW, Gaudinier A, Brady SM, Hennig L, Rhee SY, De Smet I (2012) Systems analysis of plant functional, transcriptional, physical interaction, and metabolic networks. Plant Cell 24(10):3859-3875.
-
(2012)
Plant Cell
, vol.24
, Issue.10
, pp. 3859-3875
-
-
Bassel, G.W.1
Gaudinier, A.2
Brady, S.M.3
Hennig, L.4
Rhee, S.Y.5
De Smet, I.6
-
187
-
-
76349125292
-
Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana
-
Lee I, Ambaru B, Thakkar P, Marcotte EM, Rhee SY (2010) Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana. Nat Biotechnol 28(2):149-156.
-
(2010)
Nat Biotechnol
, vol.28
, Issue.2
, pp. 149-156
-
-
Lee, I.1
Ambaru, B.2
Thakkar, P.3
Marcotte, E.M.4
Rhee, S.Y.5
-
188
-
-
81055126078
-
Genetic dissection of the biotic stress response using a genome-scale gene network for rice
-
Lee I, Seo YS, Coltrane D, Hwang S, Oh T, Marcotte EM, Ronald PC (2011) Genetic dissection of the biotic stress response using a genome-scale gene network for rice. Proc Natl Acad Sci U S A 108(45):18548-18553.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.45
, pp. 18548-18553
-
-
Lee, I.1
Seo, Y.S.2
Coltrane, D.3
Hwang, S.4
Oh, T.5
Marcotte, E.M.6
Ronald, P.C.7
-
189
-
-
79959995342
-
Gene coexpression network alignment and conservation of gene modules between two grass species: Maize and rice
-
Ficklin SP, Feltus FA (2011) Gene coexpression network alignment and conservation of gene modules between two grass species: maize and rice. Plant Physiol 156(3):1244-1256.
-
(2011)
Plant Physiol
, vol.156
, Issue.3
, pp. 1244-1256
-
-
Ficklin, S.P.1
Feltus, F.A.2
-
190
-
-
79960642108
-
Molecular mechanisms of epistasis within and between genes
-
Lehner B (2011) Molecular mechanisms of epistasis within and between genes. Trends Genet 27(8):323-331.
-
(2011)
Trends Genet
, vol.27
, Issue.8
, pp. 323-331
-
-
Lehner, B.1
-
191
-
-
77949772292
-
Gene-environment-wide association studies: Emerging approaches
-
Thomas D (2010) Gene-environment-wide association studies: emerging approaches. Nat Rev Genet 11(4):259-272.
-
(2010)
Nat Rev Genet
, vol.11
, Issue.4
, pp. 259-272
-
-
Thomas, D.1
|